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DK3131920T3 - Msp-nanoporer og anvendelser deraf - Google Patents

Msp-nanoporer og anvendelser deraf Download PDF

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Publication number
DK3131920T3
DK3131920T3 DK15779198.9T DK15779198T DK3131920T3 DK 3131920 T3 DK3131920 T3 DK 3131920T3 DK 15779198 T DK15779198 T DK 15779198T DK 3131920 T3 DK3131920 T3 DK 3131920T3
Authority
DK
Denmark
Prior art keywords
nanopores
msp
msp nanopores
Prior art date
Application number
DK15779198.9T
Other languages
English (en)
Inventor
Michael Niederweis
Mikhail Pavlenok
Original Assignee
Uab Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab Res Found filed Critical Uab Res Found
Application granted granted Critical
Publication of DK3131920T3 publication Critical patent/DK3131920T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44743Introducing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721Investigating individual macromolecules, e.g. by translocation through nanopores

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nanotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK15779198.9T 2014-04-16 2015-04-16 Msp-nanoporer og anvendelser deraf DK3131920T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461980393P 2014-04-16 2014-04-16
US201461980415P 2014-04-16 2014-04-16
PCT/US2015/026239 WO2015161117A2 (en) 2014-04-16 2015-04-16 Msp nanopores and uses thereof

Publications (1)

Publication Number Publication Date
DK3131920T3 true DK3131920T3 (da) 2021-11-22

Family

ID=54324710

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15779198.9T DK3131920T3 (da) 2014-04-16 2015-04-16 Msp-nanoporer og anvendelser deraf

Country Status (7)

Country Link
US (5) US10781237B2 (da)
EP (2) EP3978516A1 (da)
CN (1) CN107207571A (da)
CA (2) CA3207570A1 (da)
DK (1) DK3131920T3 (da)
ES (1) ES2895625T3 (da)
WO (1) WO2015161117A2 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3131920T3 (da) 2014-04-16 2021-11-22 Uab Res Found Msp-nanoporer og anvendelser deraf
GB201502810D0 (en) * 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Method
US20210325406A1 (en) * 2018-08-28 2021-10-21 Nanjing University Protein nanopore for identifying an analyte
WO2021056599A1 (zh) * 2019-09-29 2021-04-01 北京齐碳科技有限公司 一种Mnep单体变体及其应用
WO2021056598A1 (zh) * 2019-09-29 2021-04-01 北京齐碳科技有限公司 一种Mmup单体变体及其应用
NL2024579B1 (en) 2019-12-24 2021-09-06 Univ Delft Tech Protein and peptide fingerprinting and sequencing by nanopore translocation of peptide-oligonucleotide complexes
WO2023049357A2 (en) * 2021-09-24 2023-03-30 The Uab Research Foundation Control of subunit stoichiometry in single-chain msp nanopores

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07248329A (ja) 1994-03-11 1995-09-26 Nippon Bio Ratsudo Lab Kk 結核感染症検査用膜およびこれを用いる結核感染症関連抗体の検出方法
US5795782A (en) 1995-03-17 1998-08-18 President & Fellows Of Harvard College Characterization of individual polymer molecules based on monomer-interface interactions
US6362002B1 (en) 1995-03-17 2002-03-26 President And Fellows Of Harvard College Characterization of individual polymer molecules based on monomer-interface interactions
US6406880B1 (en) 1997-05-02 2002-06-18 Integrated Research Technology, Llc Betaines as adjuvants to susceptibility testing and antimicrobial therapy
US6267872B1 (en) 1998-11-06 2001-07-31 The Regents Of The University Of California Miniature support for thin films containing single channels or nanopores and methods for using same
WO2001016327A2 (de) 1999-08-31 2001-03-08 Michael Niederweis Verfahren zur herstellung eines kanalbildenden proteins
DE19941448A1 (de) 1999-08-31 2001-03-01 Stefan Bossmann Verfahren zur Herstellung von regelmäßigen Nanostrukturen
DE60025739T2 (de) 1999-09-07 2006-08-31 The Regents Of The University Of California, Oakland Verfahren um die anwesenheit von doppelsträngiger dns in einer probe nachzuweisen
JP2004512062A (ja) 2000-07-28 2004-04-22 エモリー ユニバーシテイ 人工膜から成る生物学的構成要素
AU2002239284A1 (en) 2000-11-27 2002-06-03 The Regents Of The University Of California Methods and devices for characterizing duplex nucleic acid molecules
ITMI20022096A1 (it) 2002-10-03 2004-04-04 Garden Ventures S R L Sistema di registrazione di un programma tv impostabile
US7444053B2 (en) 2003-06-16 2008-10-28 The Regents Of The University Of California Integrated electrical and optical sensor for biomolecule analysis with single molecule sensitivity
WO2006028508A2 (en) 2004-03-23 2006-03-16 President And Fellows Of Harvard College Methods and apparatus for characterizing polynucleotides
US20070269843A1 (en) 2004-04-28 2007-11-22 Integrated Research Technology, Llc. Diagnostic Assays That Use Mycobacteriophages
WO2007041621A2 (en) 2005-10-03 2007-04-12 Xingsheng Sean Ling Hybridization assisted nanopore sequencing
WO2007146158A1 (en) 2006-06-07 2007-12-21 The Trustees Of Columbia University In The City Of New York Dna sequencing by nanopore using modified nucleotides
GB2453377A (en) 2007-10-05 2009-04-08 Isis Innovation Transmembrane protein pores and molecular adapters therefore.
EP3029467B1 (en) 2008-09-22 2020-01-08 University of Washington Msp nanopores and related methods
CA2790672C (en) * 2010-02-23 2018-05-29 University Of Washington Artificial mycolic acid membranes
ES2598500T3 (es) 2010-02-24 2017-01-27 Relypsa, Inc. Poliimidazoles para su uso como secuestrantes de ácidos biliares
KR101939420B1 (ko) 2011-02-11 2019-01-16 옥스포드 나노포어 테크놀로지즈 리미티드 돌연변이체 세공
DK3131920T3 (da) 2014-04-16 2021-11-22 Uab Res Found Msp-nanoporer og anvendelser deraf
EP3137490B1 (en) 2014-05-02 2021-01-27 Oxford Nanopore Technologies Limited Mutant pores

Also Published As

Publication number Publication date
US20250230201A1 (en) 2025-07-17
US11292817B2 (en) 2022-04-05
US20170029475A1 (en) 2017-02-02
CA2945788A1 (en) 2015-10-22
EP3131920A2 (en) 2017-02-22
US20210040163A1 (en) 2021-02-11
EP3131920A4 (en) 2017-10-25
US20240174721A1 (en) 2024-05-30
EP3131920B1 (en) 2021-09-01
WO2015161117A3 (en) 2016-12-08
US12312385B2 (en) 2025-05-27
EP3978516A1 (en) 2022-04-06
CA3207570A1 (en) 2015-10-22
WO2015161117A2 (en) 2015-10-22
ES2895625T3 (es) 2022-02-22
CA2945788C (en) 2023-09-26
US20220169683A1 (en) 2022-06-02
CN107207571A (zh) 2017-09-26
US10781237B2 (en) 2020-09-22
US11858966B2 (en) 2024-01-02

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