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DK3167044T3 - Mikrofluidindretning - Google Patents

Mikrofluidindretning Download PDF

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Publication number
DK3167044T3
DK3167044T3 DK15818165T DK15818165T DK3167044T3 DK 3167044 T3 DK3167044 T3 DK 3167044T3 DK 15818165 T DK15818165 T DK 15818165T DK 15818165 T DK15818165 T DK 15818165T DK 3167044 T3 DK3167044 T3 DK 3167044T3
Authority
DK
Denmark
Prior art keywords
microfluidic
Prior art date
Application number
DK15818165T
Other languages
English (en)
Inventor
Özden Baltekin
Dan I Andersson
Johan Elf
Original Assignee
Astrego Diagnostics Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrego Diagnostics Ab filed Critical Astrego Diagnostics Ab
Application granted granted Critical
Publication of DK3167044T3 publication Critical patent/DK3167044T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18Testing for antimicrobial activity of a material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6874Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/4833Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Toxicology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Fluid Mechanics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Optical Measuring Cells (AREA)
DK15818165T 2014-07-07 2015-06-12 Mikrofluidindretning DK3167044T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1450860 2014-07-07
PCT/SE2015/050227 WO2016007063A1 (en) 2014-07-07 2015-02-27 Phenotypic characterization and in situ genotyping of a library of genetically different cells
PCT/SE2015/050685 WO2016007068A1 (en) 2014-07-07 2015-06-12 Microfluidic device

Publications (1)

Publication Number Publication Date
DK3167044T3 true DK3167044T3 (da) 2019-12-02

Family

ID=55064558

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15818165T DK3167044T3 (da) 2014-07-07 2015-06-12 Mikrofluidindretning

Country Status (11)

Country Link
US (3) US10570437B2 (da)
EP (2) EP3167061B1 (da)
JP (3) JP6600349B2 (da)
CN (2) CN106471122B (da)
AU (2) AU2015288389B2 (da)
BR (2) BR112017000168B1 (da)
CA (2) CA2954360C (da)
DK (1) DK3167044T3 (da)
ES (1) ES2762914T3 (da)
PL (1) PL3167044T3 (da)
WO (2) WO2016007063A1 (da)

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* Cited by examiner, † Cited by third party
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CA2954360C (en) * 2014-07-07 2022-11-22 Johan ELF Phenotypic characterization and in situ genotyping of a library of genetically different cells
WO2016149422A1 (en) 2015-03-16 2016-09-22 The Broad Institute, Inc. Encoding of dna vector identity via iterative hybridization detection of a barcode transcript
CA2983932C (en) * 2015-05-11 2023-07-25 Illumina, Inc. Platform for discovery and analysis of therapeutic agents
EP3472359B1 (en) * 2016-06-21 2022-03-16 10X Genomics, Inc. Nucleic acid sequencing
DK3601588T3 (da) 2017-03-22 2023-08-28 Astrego Diagnostics Ab Fænotypisk karakterisering af celler
EP3704058A4 (en) 2017-10-31 2021-11-10 Astrego Diagnostics AB MICROFLUIDIC DEVICE FOR CELLULAR CHARACTERIZATION
US11200986B2 (en) 2017-11-10 2021-12-14 Reliant Immune Diagnostics, Inc. Database and machine learning in response to parallel serial dual microfluidic chip
US10930381B2 (en) 2017-11-10 2021-02-23 Reliant Immune Diagnostics, Inc. Microfluidic testing system for mobile veterinary applications
US11527324B2 (en) 2017-11-10 2022-12-13 Reliant Immune Diagnostics, Inc. Artificial intelligence response system based on testing with parallel/serial dual microfluidic chip
US11124821B2 (en) 2017-11-10 2021-09-21 Reliant Immune Diagnostics, Inc. Microfluidic testing system with cell capture/analysis regions for processing in a parallel and serial manner
US10930380B2 (en) 2017-11-10 2021-02-23 Reliant Immune Diagnostics, Inc. Communication loop and record loop system for parallel/serial dual microfluidic chip
US11041185B2 (en) 2017-11-10 2021-06-22 Reliant Immune Diagnostics, Inc. Modular parallel/serial dual microfluidic chip
JP7335249B2 (ja) * 2018-02-16 2023-08-29 アストレゴ ダイアグノスティクス エービー 微小流体装置での細胞捕捉
JP7341148B2 (ja) 2018-02-16 2023-09-08 アストレゴ ダイアグノスティクス エービー 微小流体装置
JP7282327B2 (ja) * 2018-08-23 2023-05-29 株式会社デンソー 細胞固定デバイス、細胞固定方法、及び細胞操作方法
SE542462C2 (en) 2018-09-20 2020-05-12 Astrego Diagnostics Ab Sample loading cartridge for a microfluidic device
US11421273B2 (en) * 2018-12-03 2022-08-23 California Institute Of Technology In situ readout of DNA barcodes
CN109580485A (zh) * 2019-01-18 2019-04-05 大连理工大学 一种用于红细胞超分辨成像的固定装置和使用方法
EP3953044A4 (en) * 2019-04-08 2022-06-01 Technion Research & Development Foundation Limited MULTIPLEXED NETWORK OF NANOLITER DROPLET NETWORK DEVICES
US20220333186A1 (en) * 2019-09-26 2022-10-20 Jumpcode Genomics, Inc. Method and system for targeted nucleic acid sequencing
WO2022197490A1 (en) * 2021-03-16 2022-09-22 Scale Biosciences Inc. Method for adding spatially-addressable barcodes to nucleic acids of a cellular sample in situ
EP4234087B1 (en) 2022-02-24 2024-07-03 Sysmex Astrego AB Cartridge and method of analysing a biological sample
EP4481054A1 (en) 2023-06-23 2024-12-25 Sysmex Astrego AB Bacteria classification and analysis
SE2450459A1 (en) 2024-04-26 2025-10-27 Ab Burill A microfluidic device with valves

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DE60328392D1 (de) * 2002-04-30 2009-08-27 Gyros Patent Ab Mittels einer integrierten mikrofluidischen vorrichtung
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CN101165161B (zh) * 2007-07-27 2013-10-30 中国科学院上海微系统与信息技术研究所 一种微流体浓度梯度细胞培养芯片及其制备方法和应用
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WO2014152048A2 (en) * 2013-03-14 2014-09-25 Cytonome/St, Llc Assemblies and methods for reducing optical crosstalk in particle processing systems
CA2954360C (en) 2014-07-07 2022-11-22 Johan ELF Phenotypic characterization and in situ genotyping of a library of genetically different cells

Also Published As

Publication number Publication date
US20170137861A1 (en) 2017-05-18
AU2015288329B2 (en) 2020-07-23
US20170159048A1 (en) 2017-06-08
ES2762914T3 (es) 2020-05-26
CN106661530A (zh) 2017-05-10
BR112017000168A2 (pt) 2018-01-16
PL3167044T3 (pl) 2020-08-24
CA2954360C (en) 2022-11-22
EP3167061A4 (en) 2018-02-28
EP3167044A4 (en) 2018-06-20
BR112017000167A2 (pt) 2018-01-16
JP6629287B2 (ja) 2020-01-15
BR112017000168B1 (pt) 2023-04-18
JP2017520262A (ja) 2017-07-27
EP3167044B1 (en) 2019-10-09
CA2954378C (en) 2022-11-22
CA2954360A1 (en) 2016-01-14
CA2954378A1 (en) 2016-01-14
AU2015288389A1 (en) 2017-01-12
EP3167044A1 (en) 2017-05-17
US20180320216A1 (en) 2018-11-08
AU2015288389B2 (en) 2021-05-13
BR112017000167B1 (pt) 2021-08-24
JP6600349B2 (ja) 2019-10-30
JP2017519517A (ja) 2017-07-20
CN106471122A (zh) 2017-03-01
CN106471122B (zh) 2020-07-03
CN106661530B (zh) 2021-06-04
US10570437B2 (en) 2020-02-25
AU2015288329A1 (en) 2017-01-12
JP2020054365A (ja) 2020-04-09
US10041104B2 (en) 2018-08-07
US10913969B2 (en) 2021-02-09
JP7066206B2 (ja) 2022-05-13
EP3167061B1 (en) 2019-02-20
EP3167061A1 (en) 2017-05-17
WO2016007063A1 (en) 2016-01-14
WO2016007068A1 (en) 2016-01-14

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