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DK3129779T3 - Fremgangsmåder og sammensætninger til påvisning af fejlfoldede proteiner - Google Patents

Fremgangsmåder og sammensætninger til påvisning af fejlfoldede proteiner Download PDF

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Publication number
DK3129779T3
DK3129779T3 DK15776737.7T DK15776737T DK3129779T3 DK 3129779 T3 DK3129779 T3 DK 3129779T3 DK 15776737 T DK15776737 T DK 15776737T DK 3129779 T3 DK3129779 T3 DK 3129779T3
Authority
DK
Denmark
Prior art keywords
proteins
procedures
compositions
professional
detecting
Prior art date
Application number
DK15776737.7T
Other languages
English (en)
Inventor
Irina Buhimschi
Catalin S Buhimschi
Michael Choma
Hemant Tagare
Stephan Michael Jonas
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale filed Critical Univ Yale
Application granted granted Critical
Publication of DK3129779T3 publication Critical patent/DK3129779T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6827Total protein determination, e.g. albumin in urine
    • G01N33/6839Total protein determination, e.g. albumin in urine involving dyes, e.g. Coomassie blue, bromcresol green
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00Dyes not provided for by a single group of this subclass
    • C09B69/10Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
    • C09B69/106Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing an azo dye
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • G01N2800/368Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK15776737.7T 2014-04-10 2015-04-10 Fremgangsmåder og sammensætninger til påvisning af fejlfoldede proteiner DK3129779T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461978158P 2014-04-10 2014-04-10
PCT/US2015/025432 WO2015157704A2 (en) 2014-04-10 2015-04-10 Methods and compositions for detecting misfolded proteins

Publications (1)

Publication Number Publication Date
DK3129779T3 true DK3129779T3 (da) 2020-09-07

Family

ID=54264908

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15776737.7T DK3129779T3 (da) 2014-04-10 2015-04-10 Fremgangsmåder og sammensætninger til påvisning af fejlfoldede proteiner

Country Status (11)

Country Link
US (3) US10324094B2 (da)
EP (2) EP3745127B1 (da)
JP (1) JP6697394B2 (da)
CN (2) CN116027043A (da)
AU (3) AU2015243171B2 (da)
CA (2) CA2945058C (da)
DK (1) DK3129779T3 (da)
ES (1) ES2817417T3 (da)
MX (2) MX383381B (da)
WO (1) WO2015157704A2 (da)
ZA (1) ZA201606987B (da)

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WO2010062377A2 (en) 2008-10-31 2010-06-03 Yale University Methods and compositions for the detection and treatment of preeclampsia
ES2817417T3 (es) 2014-04-10 2021-04-07 Univ Yale Métodos y composiciones para la detección de proteínas mal plegadas
PL3322985T3 (pl) 2015-07-15 2022-02-21 GestVision, Inc. Urządzenie do wykrywania nieprawidłowo pofałdowanych białek i sposoby jego wykorzystania
US11344121B2 (en) 2016-04-14 2022-05-31 The Texas A&M University System Methods of predicting preeclampsia using biomarkers
US10345244B2 (en) * 2016-06-03 2019-07-09 International Business Machines Corporation Diagnostic test device with patterned material spots
US10335045B2 (en) 2016-06-24 2019-07-02 Universita Degli Studi Di Trento Self-adaptive matrix completion for heart rate estimation from face videos under realistic conditions
US10269107B2 (en) * 2017-02-23 2019-04-23 Global Neighbor Inc Selective plant detection and treatment using green luminance photometric machine vision scan with real time chromaticity operations and image parameter floors for low processing load
AU2018345841A1 (en) 2017-10-06 2020-05-21 The Research Foundation For The State University For The State Of New York Selective optical aqueous and non-aqueous detection of free sulfites
CN210123442U (zh) * 2017-12-28 2020-03-03 浙江数问生物技术有限公司 一种检测错误折叠蛋白质的装置
US11255844B2 (en) * 2018-03-06 2022-02-22 Fresenius Medical Care Holdings, Inc. Peritoneal dialysis systems and related methods
CN109659011A (zh) * 2018-12-29 2019-04-19 杭州脉流科技有限公司 利用移动设备采集处理十二导联ecg图像的方法以及移动设备和计算机可读存储介质
WO2022099319A1 (en) * 2020-11-06 2022-05-12 The Board Of Trustees Of The Leland Stanford Junior Universityan Systems and methods for evaluating gestational progress and applications thereof
MX2023006026A (es) * 2020-11-21 2023-07-04 Shuwen Biotech Co Ltd Aparato y metodo para detectar una proteina mal plegada en una muestra biologica.
WO2022235564A1 (en) * 2021-05-03 2022-11-10 Memorial Sloan Kettering Cancer Center Detection of labels in biomedical images
CN119522366A (zh) * 2022-05-20 2025-02-25 数问生物技术(宣城)有限公司 用于检测生物样本中的错误折叠蛋白质的装置和系统
WO2024249849A2 (en) * 2023-05-31 2024-12-05 Northwestern University Scalable platform for single cell proteomics via digitized detection of proteins and their proteoforms
CN117236201B (zh) * 2023-11-16 2024-02-23 南京信息工程大学 一种基于Diffusion和ViT的降尺度方法
CN120761295A (zh) * 2025-08-21 2025-10-10 赛克赛斯生物科技股份有限公司 三苯甲烷类化合物在检测阿尔茨海默症中的应用

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US234610A (en) * 1880-11-16 Robert o
US4444879A (en) 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
WO1992017769A1 (en) * 1991-03-28 1992-10-15 Micro Research Inc. Controlled-release solid phase assay device including encapsulated reagents for detecting chemical substances
US5998216A (en) 1996-10-01 1999-12-07 Beth Israel Deaconess Medical Center Stabilizing formulation for preserving the integrity of proteins present in a body fluid sampled ex-vivo for evaluation as a specimen
CA2275708A1 (en) 1996-12-23 1998-07-02 Cambridge University Technical Services Limited Diagnosis and treatment of pathological pregnancies
US6444435B1 (en) * 2000-11-30 2002-09-03 Serim Research Corporation Test strip for determining dialysate composition
US7355044B2 (en) 2001-10-25 2008-04-08 Agfa-Gevaert N.V. Self-assembling dyes
DK2305301T3 (da) 2002-07-19 2015-04-13 Beth Israel Hospital Fremgangsmåder til behandling af præeklampsi
US8871447B2 (en) 2002-09-12 2014-10-28 The Regents Of The University Of California Immunogens and corresponding antibodies specific for high molecular weight aggregation intermediates common to amyloids formed from proteins of differing sequence
BRPI0519096A2 (pt) 2004-12-15 2008-12-23 Beth Israel Hospital Ácidos nuclÉicos e polipeptÍdeos éteis para o diagnàstico e tratamento de complicaÇÕes na gravidez
US7727733B2 (en) 2004-12-21 2010-06-01 Yale University Diagnosis of preeclampsia
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WO2010062377A2 (en) * 2008-10-31 2010-06-03 Yale University Methods and compositions for the detection and treatment of preeclampsia
CN103012599B (zh) * 2012-11-28 2015-04-29 龙岩九健生物芯片技术研究所 一种调节硝酸纤维素硝化取代度的方法
ES2817417T3 (es) 2014-04-10 2021-04-07 Univ Yale Métodos y composiciones para la detección de proteínas mal plegadas

Also Published As

Publication number Publication date
CN106461644A (zh) 2017-02-22
MX2016013255A (es) 2017-05-03
CA2945058C (en) 2022-07-12
ZA201606987B (en) 2020-01-29
EP3745127B1 (en) 2024-08-28
MX2021006791A (es) 2021-07-15
ES2817417T3 (es) 2021-04-07
US20190353662A1 (en) 2019-11-21
US20220043001A1 (en) 2022-02-10
US11953505B2 (en) 2024-04-09
EP3745127A1 (en) 2020-12-02
US11079392B2 (en) 2021-08-03
CN116027043A (zh) 2023-04-28
AU2020244572B2 (en) 2022-12-15
CA2945058A1 (en) 2015-10-15
AU2020244572A1 (en) 2020-11-05
US10324094B2 (en) 2019-06-18
EP3129779A2 (en) 2017-02-15
US20150293115A1 (en) 2015-10-15
AU2015243171A1 (en) 2016-10-27
WO2015157704A3 (en) 2016-04-28
AU2022291625A1 (en) 2023-02-16
MX383381B (es) 2025-03-13
EP3129779B1 (en) 2020-06-03
AU2015243171B2 (en) 2020-10-15
JP6697394B2 (ja) 2020-05-20
CN106461644B (zh) 2022-05-13
AU2022291625B2 (en) 2024-09-12
JP2017518483A (ja) 2017-07-06
WO2015157704A2 (en) 2015-10-15
CA3157573A1 (en) 2015-10-15

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