DK3110947T3 - Diacylglycerolacyltransferase (dga1)-polynukleotider og fremgangsmåder til forøgelse af gærcellelipidfremstilling ved hjælp af overekspression af heterolog dga1 - Google Patents
Diacylglycerolacyltransferase (dga1)-polynukleotider og fremgangsmåder til forøgelse af gærcellelipidfremstilling ved hjælp af overekspression af heterolog dga1 Download PDFInfo
- Publication number
- DK3110947T3 DK3110947T3 DK15751487T DK15751487T DK3110947T3 DK 3110947 T3 DK3110947 T3 DK 3110947T3 DK 15751487 T DK15751487 T DK 15751487T DK 15751487 T DK15751487 T DK 15751487T DK 3110947 T3 DK3110947 T3 DK 3110947T3
- Authority
- DK
- Denmark
- Prior art keywords
- dga1
- transpherase
- glycerolacyl
- heterologic
- diacyl
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000002018 overexpression Effects 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 210000005253 yeast cell Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/0102—Diacylglycerol O-acyltransferase (2.3.1.20)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461943664P | 2014-02-24 | 2014-02-24 | |
| PCT/US2015/017227 WO2015127421A1 (en) | 2014-02-24 | 2015-02-24 | Diacylglycerol acyl transferase (dga1) polynucleotides, and methods of increasing yeast cell lipid production by overexpression of heterologous dga1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3110947T3 true DK3110947T3 (da) | 2019-11-04 |
Family
ID=53879132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15751487T DK3110947T3 (da) | 2014-02-24 | 2015-02-24 | Diacylglycerolacyltransferase (dga1)-polynukleotider og fremgangsmåder til forøgelse af gærcellelipidfremstilling ved hjælp af overekspression af heterolog dga1 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US10260052B2 (da) |
| EP (1) | EP3110947B1 (da) |
| CN (2) | CN106574257B (da) |
| AU (2) | AU2015218647B2 (da) |
| DK (1) | DK3110947T3 (da) |
| WO (1) | WO2015127421A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015218647B2 (en) * | 2014-02-24 | 2021-10-21 | Ginkgo Bioworks, Inc. | Diacylglycerol acyl transferase (DGA1) polynucleotides, and methods of increasing yeast cell lipid production by overexpression of heterologous DGA1 |
| WO2015184303A1 (en) | 2014-05-29 | 2015-12-03 | Novogy, Inc. | Increasing lipid production in oleaginous yeast |
| US11208649B2 (en) | 2015-12-07 | 2021-12-28 | Zymergen Inc. | HTP genomic engineering platform |
| US9988624B2 (en) | 2015-12-07 | 2018-06-05 | Zymergen Inc. | Microbial strain improvement by a HTP genomic engineering platform |
| CN113337410A (zh) * | 2021-06-04 | 2021-09-03 | 广西壮族自治区亚热带作物研究所(广西亚热带农产品加工研究所) | 一种防治百香果黑斑病的药剂及其制备方法 |
| CN116555362A (zh) * | 2022-01-29 | 2023-08-08 | 罗盖特公司 | 使用解脂耶氏酵母生产脂质的方法 |
| CN116396875A (zh) * | 2022-12-20 | 2023-07-07 | 华东理工大学 | 一种解脂耶氏酵母基因工程菌及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6791008B1 (en) * | 1999-11-12 | 2004-09-14 | Scandinavian Biotechnology Research (Scanbi) Ab | Use of a class of enzymes and their encoding genes to increase the oil content in transgenic organisms |
| KR20020026053A (ko) * | 2000-09-30 | 2002-04-06 | 노승권 | 음료용 식물성 스테롤의 분산방법 및 이를 함유하는 음료 |
| CA2492205A1 (en) * | 2002-07-31 | 2004-02-05 | Monsanto Technology, Llc | Diacylglycerol acyltransferase nucleic acid sequences and associated products |
| US7550286B2 (en) * | 2004-11-04 | 2009-06-23 | E. I. Du Pont De Nemours And Company | Docosahexaenoic acid producing strains of Yarrowia lipolytica |
| US7273746B2 (en) * | 2004-11-04 | 2007-09-25 | E.I. Dupont De Nemours And Company | Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
| EP2730656A1 (en) * | 2007-05-24 | 2014-05-14 | E. I. du Pont de Nemours and Company | Soybean meal from beans having DGAT genes from yarrowia lipolytica for increased seed storage lipid production and altered fatty acid profiles in soybean |
| EP2620501A3 (en) * | 2008-05-23 | 2013-10-02 | E. I. du Pont de Nemours and Company | DGAT genes from oleaginous organisms for increased seed storage lipid production and altered fatty acid profiles in oilseed plants |
| US8502026B2 (en) * | 2009-08-24 | 2013-08-06 | Monsanto Technology Llc | Transgenic plants with enhanced agronomic traits |
| BR112012011980A2 (pt) * | 2009-11-19 | 2021-09-08 | Oxyrane Uk Limited | Métodos de produzir células transformadas de yarrowia lipolytica e proteínas-alvocompreendendo n-glicanos, células transformadas de yarrowia lipolytica e suas culturas, bem como composição compreendendo glicoproteínas |
| CA2804025C (en) * | 2010-06-28 | 2023-02-21 | Commonwealth Scientific And Industrial Research Organisation | Methods of producing lipids |
| EP2714724A1 (en) | 2011-05-26 | 2014-04-09 | E. I. Du Pont de Nemours and Company | Expression of caleosin in recombinant oleaginous microorganisms to increase oil content therein |
| AU2015218647B2 (en) * | 2014-02-24 | 2021-10-21 | Ginkgo Bioworks, Inc. | Diacylglycerol acyl transferase (DGA1) polynucleotides, and methods of increasing yeast cell lipid production by overexpression of heterologous DGA1 |
-
2015
- 2015-02-24 AU AU2015218647A patent/AU2015218647B2/en not_active Ceased
- 2015-02-24 US US15/120,952 patent/US10260052B2/en active Active
- 2015-02-24 DK DK15751487T patent/DK3110947T3/da active
- 2015-02-24 CN CN201580021065.7A patent/CN106574257B/zh not_active Expired - Fee Related
- 2015-02-24 WO PCT/US2015/017227 patent/WO2015127421A1/en not_active Ceased
- 2015-02-24 CN CN202110290143.0A patent/CN113151319A/zh active Pending
- 2015-02-24 EP EP15751487.8A patent/EP3110947B1/en active Active
-
2019
- 2019-02-28 US US16/288,544 patent/US11352610B2/en active Active
-
2022
- 2022-01-11 AU AU2022200122A patent/AU2022200122A1/en not_active Abandoned
- 2022-06-06 US US17/833,453 patent/US20220380737A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN113151319A (zh) | 2021-07-23 |
| US20160362663A1 (en) | 2016-12-15 |
| CN106574257A (zh) | 2017-04-19 |
| US20220380737A1 (en) | 2022-12-01 |
| AU2022200122A1 (en) | 2022-02-10 |
| US10260052B2 (en) | 2019-04-16 |
| EP3110947A1 (en) | 2017-01-04 |
| AU2015218647A1 (en) | 2016-09-08 |
| US20190316098A1 (en) | 2019-10-17 |
| US11352610B2 (en) | 2022-06-07 |
| EP3110947A4 (en) | 2017-11-01 |
| AU2015218647B2 (en) | 2021-10-21 |
| WO2015127421A1 (en) | 2015-08-27 |
| EP3110947B1 (en) | 2019-09-04 |
| CN106574257B (zh) | 2021-06-04 |
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