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DK3104814T3 - Apparat til suprachoroidal indgivelse af terapeutisk middel - Google Patents

Apparat til suprachoroidal indgivelse af terapeutisk middel Download PDF

Info

Publication number
DK3104814T3
DK3104814T3 DK15708368.4T DK15708368T DK3104814T3 DK 3104814 T3 DK3104814 T3 DK 3104814T3 DK 15708368 T DK15708368 T DK 15708368T DK 3104814 T3 DK3104814 T3 DK 3104814T3
Authority
DK
Denmark
Prior art keywords
therapevice
suprachoroidal administration
suprachoroidal
administration
Prior art date
Application number
DK15708368.4T
Other languages
English (en)
Inventor
Brendan J Oberkircher
Daniel W Price
Michael F Keane
Saeed Sokhanvar
Daniel J Yasevac
Michel G Bruehwiler
Leah R Soffer
Isaac J Khan
Benjamin L Ko
Christopher D Riemann
Nathan D Grubbs
Original Assignee
Gyroscope Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyroscope Therapeutics Ltd filed Critical Gyroscope Therapeutics Ltd
Application granted granted Critical
Publication of DK3104814T3 publication Critical patent/DK3104814T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1585—Needle inserters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DK15708368.4T 2014-02-12 2015-02-11 Apparat til suprachoroidal indgivelse af terapeutisk middel DK3104814T3 (da)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201461938956P 2014-02-12 2014-02-12
US201462049089P 2014-09-11 2014-09-11
US201462049056P 2014-09-11 2014-09-11
US201462049100P 2014-09-11 2014-09-11
US201462049128P 2014-09-11 2014-09-11
US201562104295P 2015-01-16 2015-01-16
PCT/US2015/015362 WO2015126694A1 (en) 2014-02-12 2015-02-11 Method and apparatus for suprachoroidal administration of therapeutic agent

Publications (1)

Publication Number Publication Date
DK3104814T3 true DK3104814T3 (da) 2021-05-31

Family

ID=53773957

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15708368.4T DK3104814T3 (da) 2014-02-12 2015-02-11 Apparat til suprachoroidal indgivelse af terapeutisk middel
DK20200019.6T DK3797742T3 (da) 2014-02-12 2015-02-11 Indretning til suprakoroidal indgivelse af terapeutisk middel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK20200019.6T DK3797742T3 (da) 2014-02-12 2015-02-11 Indretning til suprakoroidal indgivelse af terapeutisk middel

Country Status (11)

Country Link
US (6) US10226379B2 (da)
EP (3) EP3104814B1 (da)
JP (5) JP6548229B2 (da)
CN (3) CN110680606B (da)
BR (2) BR112016018570B1 (da)
DK (2) DK3104814T3 (da)
ES (2) ES2871138T3 (da)
FI (1) FI3797742T3 (da)
PL (2) PL3797742T3 (da)
PT (2) PT3104814T (da)
WO (1) WO2015126694A1 (da)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
EP2627292B1 (en) * 2010-10-15 2018-10-10 Clearside Biomedical, Inc. Device for ocular access
MX372859B (es) 2013-05-03 2020-07-07 Clearside Biomedical Inc Aparatos y métodos para inyección ocular.
US10226379B2 (en) * 2014-02-12 2019-03-12 Orbit Biomedical Limited Method and apparatus for subretinal administration of therapeutic agent
US9949874B2 (en) 2014-06-06 2018-04-24 Janssen Biotech, Inc. Therapeutic agent delivery device with convergent lumen
US9925088B2 (en) * 2014-06-06 2018-03-27 Janssen Biotech, Inc. Sub-retinal tangential needle catheter guide and introducer
US10064752B2 (en) 2014-09-11 2018-09-04 Orbit Biomedical Limited Motorized suprachoroidal injection of therapeutic agent
US10322028B2 (en) 2014-09-11 2019-06-18 Orbit Biomedical Limited Method and apparatus for sensing position between layers of an eye
US10219936B2 (en) 2014-09-11 2019-03-05 Orbit Biomedical Limited Therapeutic agent delivery device with advanceable cannula and needle
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
AU2015401840B2 (en) * 2015-07-03 2019-05-09 Ophthorobotics Ag Intraocular injection system and methods for controlling such a system
ES2954983T3 (es) * 2015-09-17 2023-11-28 Oxular Ltd Dispositivo de inyección oftálmica
US11357912B2 (en) * 2016-01-19 2022-06-14 Unomedical A/S Cannula and infusion devices
US10478553B2 (en) * 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle
CN109640899B (zh) * 2016-03-16 2022-04-08 奥叙拉尔有限公司 眼科递送装置和眼科药物组合物
WO2017192565A1 (en) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
US10806629B2 (en) * 2016-06-17 2020-10-20 Gyroscope Therapeutics Limited Injection device for subretinal delivery of therapeutic agent
US11000410B2 (en) 2016-06-17 2021-05-11 Gyroscope Therapeutics Limited Guide apparatus for tangential entry into suprachoroidal space
US10646374B2 (en) 2016-06-17 2020-05-12 Orbit Biomedical Limited Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent
US10973681B2 (en) 2016-08-12 2021-04-13 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
CN109890333A (zh) * 2016-09-02 2019-06-14 爱瑞制药公司 植入物涂敷器
US20190216645A1 (en) * 2016-09-23 2019-07-18 The Regents Of The University Of California Surgical device for ab-externo sub-retinal fluid drainage
US20180092772A1 (en) * 2016-10-04 2018-04-05 Firas Emad Mosalam Automated Eye Drop Dispenser
CN114848286A (zh) 2016-12-19 2022-08-05 新世界医学有限公司 眼部治疗装置和相关使用方法
US11273072B2 (en) * 2017-01-13 2022-03-15 Gyroscope Therapeutics Limited Suprachoroidal injection device
CA3053750A1 (en) * 2017-02-16 2018-08-23 Neomedix Corporation Devices, systems and methods for minimally invasive glaucoma surgery
US11076984B2 (en) 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
US11033427B2 (en) 2017-04-13 2021-06-15 Alcon Inc. Vitreoretinal instruments for fluid aspiration
CN110072495B (zh) * 2017-06-15 2022-06-03 新加坡全国眼科中心有限公司 用于滴注滴眼剂的滴眼剂引导装置
KR20250004925A (ko) * 2017-09-15 2025-01-08 옥슬러 리미티드 안과용 약물 조성물
US11576816B2 (en) * 2017-10-18 2023-02-14 Jesus Moreno Opthalmic microsurgical instrument
TWI734958B (zh) 2018-03-19 2021-08-01 日商泰爾茂股份有限公司 穿刺針及導管組合體
CN112165923B (zh) * 2018-04-19 2023-07-21 埃弗拉兹疗法有限公司 用于将物质注射到身体组织或器官的夹层中的装置
US11338113B2 (en) 2018-06-07 2022-05-24 Becton, Dickinson And Company Needle position indicator
US11351354B2 (en) 2019-02-20 2022-06-07 Becton, Dickinson And Company Extension tube clamp providing positive displacement
US11759355B1 (en) 2019-02-26 2023-09-19 Gyroscope Therapeutics Limited Method of delivering leading blebs and agent to subretinal space
JP7179670B2 (ja) * 2019-04-18 2022-11-29 株式会社日本製鋼所 延伸装置および延伸装置の部品交換方法
USD974561S1 (en) 2019-05-17 2023-01-03 Boston Scientific Scimed Inc. Radial ultrasound needle biopsy device
US12318343B2 (en) * 2019-05-29 2025-06-03 Alcon Inc. Retina massage and smoothing device
AU2020362958A1 (en) 2019-10-11 2022-04-14 Genentech, Inc. Dose clip assembly for syringe
CN115551438A (zh) * 2020-05-21 2022-12-30 瑞德医疗机器股份有限公司 手术器具退避机构
US20240000443A1 (en) * 2020-11-30 2024-01-04 Visionaire Products, Inc. Needle and collection device for ocular biopsy and methods of use
WO2022136913A1 (en) 2020-12-22 2022-06-30 Gyroscope Therapeutics Limited Ocular cannula guide
WO2022150650A1 (en) * 2021-01-11 2022-07-14 New World Medical, Inc. Ophthalmic device
EP4291144A1 (en) 2021-02-09 2023-12-20 Gyroscope Therapeutics Limited Suprachoroidal injection device
USD1037439S1 (en) 2022-01-17 2024-07-30 EyePoint Pharamaceuticals, Inc. Ocular injector
KR102460395B1 (ko) * 2022-06-23 2022-10-27 이성헌 코 성형 또는 얼굴 리프팅용 리프팅 실의 삽입 장치
CN119562797A (zh) 2022-07-11 2025-03-04 基因泰克公司 经玻璃体视网膜下注射器
IL319330A (en) 2022-09-06 2025-05-01 Genentech Inc A device for subretinal administration of a therapeutic agent using a double curved needle
WO2024150069A2 (en) 2023-01-13 2024-07-18 Gyroscope Therapeutics Limited Dose dock for syringe
AU2024314616A1 (en) * 2023-06-22 2025-11-13 Alcon Inc. Methods and apparatus for subretinal delivery
WO2024261600A1 (en) * 2023-06-22 2024-12-26 Alcon Inc. Methods and apparatus for subretinal delivery
US20240423833A1 (en) * 2023-06-22 2024-12-26 Alcon Inc. Methods and apparatus for subretinal delivery
WO2024261624A1 (en) * 2023-06-22 2024-12-26 Alcon Inc. Methods and apparatus for subretinal delivery
WO2025072590A1 (en) 2023-09-29 2025-04-03 Genentech, Inc. Ocular cannula guide, applicator, and marking instrument
WO2025179248A1 (en) * 2024-02-23 2025-08-28 Oculogenex Inc. Microneedle device for intraocular injections and methods of using the same
WO2025207699A1 (en) 2024-03-27 2025-10-02 Genentech, Inc. Torque ring for subretinal injection device
WO2025217230A1 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Vectorized anti-complement antibodies and complement agents and administration thereof
WO2025217214A2 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Recombinant adeno-associated viruses and uses thereof
WO2025213282A1 (en) * 2024-04-12 2025-10-16 Dragonfleye Therapeutics Corp. Devices and methods for precision advancing needle with sensing

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2760483A (en) * 1953-10-29 1956-08-28 Tassicker Graham Edward Retinal stimulator
US5273530A (en) 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
US5312361A (en) * 1991-09-13 1994-05-17 Zadini Filiberto P Automatic cannulation device
US5653715A (en) * 1993-03-09 1997-08-05 Chiron Vision Corporation Apparatus for preparing an intraocular lens for insertion
US5964740A (en) 1996-07-09 1999-10-12 Asahi Kogaku Kogyo Kabushiki Kaisha Treatment accessory for an endoscope
US6283951B1 (en) * 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
DE69633411T2 (de) 1995-10-13 2005-10-20 Transvascular, Inc., Menlo Park Verfahren und vorrichtung zur umgehung von arteriellen verengungen und/oder zur ausführung anderer transvaskularer eingriffe
DE19741487C2 (de) 1997-09-19 2000-08-31 Univ Eberhard Karls Vorrichtung für einen Zugang in den Subretinalraum eines Auges
US6378526B1 (en) 1998-08-03 2002-04-30 Insite Vision, Incorporated Methods of ophthalmic administration
US6309374B1 (en) 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
US6143004A (en) * 1998-08-18 2000-11-07 Atrion Medical Products, Inc. Suturing device
KR100312659B1 (ko) 1998-09-18 2002-02-19 하권익 망막하주사기
US6162197A (en) * 1998-12-22 2000-12-19 Mohammad; Owais Retractable needle assembly and method of making the same
US6368315B1 (en) 1999-06-23 2002-04-09 Durect Corporation Composite drug delivery catheter
ES2240180T3 (es) 1999-10-21 2005-10-16 Alcon Inc. Administracion sub-tenon de medicamentos.
US8574146B2 (en) * 2000-04-14 2013-11-05 Attenuex Technologies, Inc. Implant with high vapor pressure medium
US7357794B2 (en) 2002-01-17 2008-04-15 Medtronic Vascular, Inc. Devices, systems and methods for acute or chronic delivery of substances or apparatus to extravascular treatment sites
US6989004B2 (en) 2001-02-28 2006-01-24 Rex Medical, L.P. Apparatus for delivering ablation fluid to treat lesions
US7122042B2 (en) * 2001-03-15 2006-10-17 Lorusso Frank J Apparatuses and methods for transcleral cautery and subretinal drainage
US7431710B2 (en) * 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US7485113B2 (en) 2001-06-22 2009-02-03 Johns Hopkins University Method for drug delivery through the vitreous humor
KR100431454B1 (ko) 2001-10-15 2004-05-14 사회복지법인삼성생명공익재단(삼성서울병원) 망막하 주사기
AU2003213075A1 (en) 2002-02-14 2003-09-04 Henry J. Kaplan Subretinal implantation device and surgical cannulas for use therewith
US7316676B2 (en) 2002-08-20 2008-01-08 Gholam A. Peyman Treatment of retinal detachment
CA2689424A1 (en) 2002-09-29 2004-04-08 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
WO2004066871A2 (en) 2003-01-24 2004-08-12 Doheny Retina Institute Reservoirs with subretinal cannula for subretinal drug delivery
US20040199130A1 (en) * 2003-04-03 2004-10-07 Chornenky Victor I. Apparatus and method for treatment of macular degeneration
JP4289919B2 (ja) 2003-05-06 2009-07-01 朝日インテック株式会社 薬液注入装置
US7510873B2 (en) 2003-06-27 2009-03-31 Ethicon, Incorporated Postpartum cells isolated from umbilical cord tissue, and methods of making and using the same
JP2005176919A (ja) 2003-12-16 2005-07-07 Daikyu:Kk 安全注射針
DK1715827T3 (da) 2004-01-23 2011-04-18 Iscience Interventional Corp Sammensat ophthalmisk mikrokanyle
AU2005214040B2 (en) * 2004-02-12 2011-03-31 Neo Vista, Inc. Methods and apparatus for intraocular brachytherapy
US20100173866A1 (en) * 2004-04-29 2010-07-08 Iscience Interventional Corporation Apparatus and method for ocular treatment
BRPI0510380A (pt) * 2004-04-29 2007-11-06 Iscience Surgical Corp dispositivo de micro-cánula compósito, e, métodos para tratar o espaço supracoroideano de um olho, para tratar a região posterior de um olho e para tratar os tecidos dentro ou adjacentes ao espaço supracoroideano de um olho
US20080058704A1 (en) 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
US20060047250A1 (en) * 2004-08-30 2006-03-02 Hickingbotham Dyson W Fluid delivery device
US8465451B2 (en) 2005-06-22 2013-06-18 Covidien Lp Methods and apparatus for introducing tumescent fluid to body tissue
US9084662B2 (en) 2006-01-17 2015-07-21 Transcend Medical, Inc. Drug delivery treatment device
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20080004596A1 (en) 2006-05-25 2008-01-03 Palo Alto Institute Delivery of agents by microneedle catheter
US20080281292A1 (en) 2006-10-16 2008-11-13 Hickingbotham Dyson W Retractable Injection Port
JP2008142533A (ja) * 2006-11-16 2008-06-26 Manii Kk トロカール
US8353862B2 (en) * 2007-11-02 2013-01-15 Allergan, Inc. Drug delivery systems and methods
DK2227257T3 (da) 2008-01-07 2013-09-30 Salutaris Medical Devices Inc Anordninger til minimal-invasiv ekstraokular afgivelse af stråling til den posteriore del af øjet
US20100305514A1 (en) 2008-01-10 2010-12-02 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
US20100081707A1 (en) * 2008-02-21 2010-04-01 Ali Robin R Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea
WO2010019719A2 (en) * 2008-08-13 2010-02-18 Silk Road Medical, Inc. Suture delivery device
US8425473B2 (en) 2009-01-23 2013-04-23 Iscience Interventional Corporation Subretinal access device
US8192408B2 (en) * 2009-02-10 2012-06-05 Psivida Us, Inc. Ocular trocar assembly
AU2010248912A1 (en) 2009-05-15 2011-12-08 Iscience Interventional Corporation Methods and apparatus for sub-retinal catheterization
WO2010141837A1 (en) 2009-06-05 2010-12-09 Vance Products Incorporated, D/B/A/ Cook Urological Incorporated Access sheath and needle assembly for delivering therapeutic material
EP2496304A4 (en) * 2009-11-02 2013-04-17 Salutaris Medical Devices Inc METHOD AND DEVICES FOR THE ADMINISTRATION OF MINIMALLY INVASIVE EXTRACOLAR RADIATION
RS62540B1 (sr) * 2010-08-05 2021-12-31 Forsight Vision4 Inc Aparat za lečenje oka
EP2627292B1 (en) * 2010-10-15 2018-10-10 Clearside Biomedical, Inc. Device for ocular access
US8535268B2 (en) * 2010-12-22 2013-09-17 Alcon Research, Ltd. Device for at least one of injection or aspiration
US8852165B2 (en) 2011-06-16 2014-10-07 II Edward G. Mackay Endoluminal drug delivery devices and methods
US9629675B2 (en) 2011-10-19 2017-04-25 Confluent Medical Technologies, Inc. Tissue treatment device and related methods
WO2013059668A1 (en) * 2011-10-21 2013-04-25 Synergetics, Inc. Trocar system
US9138530B2 (en) 2012-02-15 2015-09-22 The Cleveland Clinic Foundation Catheter assembly and method of treating a vascular disease
ES2842454T3 (es) * 2012-03-20 2021-07-14 Sight Sciences Inc Sistemas de entrega ocular
WO2014036009A1 (en) 2012-08-27 2014-03-06 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using microneedles
US9301795B2 (en) 2012-10-29 2016-04-05 Ablative Solutions, Inc. Transvascular catheter for extravascular delivery
MX373894B (es) 2012-11-08 2020-07-09 Clearside Biomedical Inc Métodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos.
WO2015015467A1 (en) * 2013-08-02 2015-02-05 Tel Hashomer Medical Research Infrastructure And Services Ltd. A device for delivery of compositions to the eye
US10226379B2 (en) * 2014-02-12 2019-03-12 Orbit Biomedical Limited Method and apparatus for subretinal administration of therapeutic agent
US9949874B2 (en) 2014-06-06 2018-04-24 Janssen Biotech, Inc. Therapeutic agent delivery device with convergent lumen
US9925088B2 (en) 2014-06-06 2018-03-27 Janssen Biotech, Inc. Sub-retinal tangential needle catheter guide and introducer
BR112016029864A2 (pt) 2014-06-17 2017-08-22 Clearside Biomedical Inc métodos e dispositivos para tratamento de desordens oculares posteriores.
CN106794321A (zh) 2014-06-20 2017-05-31 科尼尔赛德生物医学公司 可变直径插管以及用于控制对药剂递送的插入深度的方法
US10219936B2 (en) 2014-09-11 2019-03-05 Orbit Biomedical Limited Therapeutic agent delivery device with advanceable cannula and needle
US10064752B2 (en) 2014-09-11 2018-09-04 Orbit Biomedical Limited Motorized suprachoroidal injection of therapeutic agent
US10322028B2 (en) 2014-09-11 2019-06-18 Orbit Biomedical Limited Method and apparatus for sensing position between layers of an eye
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
CN107847670B (zh) * 2015-07-30 2020-09-04 泰尔茂株式会社 医疗用穿刺针和穿刺针的制造方法
GB201516066D0 (en) 2015-09-10 2015-10-28 Young & Co Llp D Treatment of retinitis pigmentosa
US11273072B2 (en) * 2017-01-13 2022-03-15 Gyroscope Therapeutics Limited Suprachoroidal injection device
US10765843B2 (en) * 2018-12-31 2020-09-08 J.D. Franco & Co., Llc Intravascular devices, systems, and methods to address eye disorders

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US20190142635A1 (en) 2019-05-16
PL3797742T3 (pl) 2025-04-14
EP3797742B1 (en) 2025-01-01
PT3797742T (pt) 2025-03-10
CN113855385B (zh) 2024-06-25
BR122020011529B1 (pt) 2022-11-29
JP7483826B2 (ja) 2024-05-15
US20150223977A1 (en) 2015-08-13
US20210298951A1 (en) 2021-09-30
PL3104814T3 (pl) 2021-10-11
US20240277518A1 (en) 2024-08-22
JP2019147052A (ja) 2019-09-05
PT3104814T (pt) 2021-06-17
EP3104814B1 (en) 2021-04-07
JP2022186880A (ja) 2022-12-15
DK3797742T3 (da) 2025-01-20
EP3104814A1 (en) 2016-12-21
US12409064B2 (en) 2025-09-09
JP7167197B2 (ja) 2022-11-08
CN106687078A (zh) 2017-05-17
US11554042B2 (en) 2023-01-17
ES3013632T3 (en) 2025-04-14
US10226379B2 (en) 2019-03-12
JP2021058723A (ja) 2021-04-15
US20190142634A1 (en) 2019-05-16
FI3797742T3 (fi) 2025-03-04
BR112016018570A2 (pt) 2018-06-26
JP6995800B2 (ja) 2022-01-17
US20250295522A1 (en) 2025-09-25
EP3797742A1 (en) 2021-03-31
US11998482B2 (en) 2024-06-04
JP2024096296A (ja) 2024-07-12
WO2015126694A1 (en) 2015-08-27
US11058576B2 (en) 2021-07-13
JP6548229B2 (ja) 2019-07-24
JP2017505686A (ja) 2017-02-23
BR112016018570B1 (pt) 2022-08-30
CN110680606B (zh) 2023-07-21
CN106687078B (zh) 2019-10-25
CN110680606A (zh) 2020-01-14
CN113855385A (zh) 2021-12-31
EP4555981A2 (en) 2025-05-21
ES2871138T3 (es) 2021-10-28
EP4555981A3 (en) 2025-08-06

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