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DK3068747T3 - Dobbeltkørselskassette til syntese af 18f-mærkede forbindelser - Google Patents

Dobbeltkørselskassette til syntese af 18f-mærkede forbindelser Download PDF

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Publication number
DK3068747T3
DK3068747T3 DK14796762.4T DK14796762T DK3068747T3 DK 3068747 T3 DK3068747 T3 DK 3068747T3 DK 14796762 T DK14796762 T DK 14796762T DK 3068747 T3 DK3068747 T3 DK 3068747T3
Authority
DK
Denmark
Prior art keywords
synthesis
double
labeled compounds
run cassette
cassette
Prior art date
Application number
DK14796762.4T
Other languages
English (en)
Inventor
Xavier Franci
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Application granted granted Critical
Publication of DK3068747T3 publication Critical patent/DK3068747T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/005Sugars; Derivatives thereof; Nucleosides; Nucleotides; Nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0491Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00495Means for heating or cooling the reaction vessels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00709Type of synthesis
    • B01J2219/00716Heat activated synthesis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00731Saccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DK14796762.4T 2013-11-13 2014-11-12 Dobbeltkørselskassette til syntese af 18f-mærkede forbindelser DK3068747T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361903486P 2013-11-13 2013-11-13
PCT/EP2014/074330 WO2015071288A1 (en) 2013-11-13 2014-11-12 Dual run cassette for the synthesis of 18f-labelled compounds

Publications (1)

Publication Number Publication Date
DK3068747T3 true DK3068747T3 (da) 2025-01-13

Family

ID=51897262

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14796762.4T DK3068747T3 (da) 2013-11-13 2014-11-12 Dobbeltkørselskassette til syntese af 18f-mærkede forbindelser

Country Status (18)

Country Link
US (1) US10584078B2 (da)
EP (1) EP3068747B1 (da)
JP (1) JP6496726B2 (da)
KR (1) KR102335535B1 (da)
CN (2) CN113564722A (da)
BE (1) BE1022357A9 (da)
CA (1) CA2930479C (da)
DE (2) DE202014010612U1 (da)
DK (1) DK3068747T3 (da)
ES (1) ES3005832T3 (da)
FI (1) FI3068747T3 (da)
HR (1) HRP20250050T1 (da)
HU (1) HUE069777T2 (da)
IL (1) IL235650B (da)
PL (1) PL3068747T3 (da)
PT (1) PT3068747T (da)
RS (1) RS66442B1 (da)
WO (1) WO2015071288A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201420094D0 (en) * 2014-11-12 2014-12-24 Ge Healthcare Ltd Flouride trapping arrangement
US10109385B2 (en) 2009-09-23 2018-10-23 Abt Molecular Imaging, Inc. Dose synthesis card for use with automated biomarker production system
HRP20250050T1 (hr) * 2013-11-13 2025-04-11 Ge Healthcare Limited Kaseta za dvostruku obradu za sintezu spojeva obilježenih radioizotopom 18f
GB201420093D0 (en) 2014-11-12 2014-12-24 Ge Healthcare Ltd Pet tracer purification system
CN107530455A (zh) * 2015-02-10 2018-01-02 Abt分子成像公司 与自动化生物标记物生产系统联用的剂量合成卡
GB201504287D0 (en) 2015-03-13 2015-04-29 Ge Healthcare Ltd Piercing device
NL2014828B1 (en) 2015-05-20 2017-01-31 Out And Out Chemistry S P R L Method of performing a plurality of synthesis processes of preparing a radiopharmaceutical in series, a device and cassette for performing this method.
WO2018236115A1 (ko) 2017-06-19 2018-12-27 (주)퓨쳐켐 전립선암 진단을 위한 18f-표지된 화합물 및 그의 용도
EP3643707B1 (en) 2017-06-19 2022-02-23 Futurechem Co., Ltd. 18f-labelled compound for prostate cancer diagnosis, and use thereof
WO2019058947A1 (ja) * 2017-09-19 2019-03-28 株式会社村田製作所 濾過装置及び濾過方法
JP6927314B2 (ja) 2017-09-25 2021-08-25 株式会社村田製作所 濾過装置
CN108126648A (zh) * 2018-01-04 2018-06-08 江苏华益科技有限公司 一种放射性药物的自动传输装置及方法
CN113413840A (zh) * 2021-06-04 2021-09-21 四川玖谊源粒子科技有限公司 一种用于制备多核素放射性药物的合成系统
BE1032491B1 (fr) 2024-03-27 2025-10-27 Trasis S A Synthèse de traceurs à plusieurs passages sur cassette

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5082980A (en) * 1990-06-13 1992-01-21 Case Western Reserve University Process and apparatus for synthesizing oxygen-15 labelled butanol for positron emission tomography
US7413714B1 (en) 2000-07-16 2008-08-19 Ymc Co. Ltd. Sequential reaction system
CN100374453C (zh) * 2005-11-18 2008-03-12 南方医科大学南方医院 2-18f-2-脱氧-d-葡萄糖的合成工艺
CA2632553A1 (en) * 2005-12-02 2007-06-07 Nihon Medi-Physics Co., Ltd. Process for production of compound labeled with radioactive fluorine
JP4926546B2 (ja) * 2006-05-30 2012-05-09 住友重機械工業株式会社 放射性薬液合成装置の使用方法、及び放射性薬液合成装置
EP2379757A2 (en) * 2008-12-22 2011-10-26 Bayer Pharma Aktiengesellschaft A method for the synthesis of a radionuclide-labeled compound
CN101830937B (zh) * 2009-03-12 2012-06-06 张锦明 可视化、双反应管氟-18多功能自动化合成模块
JP2012532164A (ja) * 2009-07-10 2012-12-13 バイエル ファーマ アクチエンゲゼルシャフト 放射性トレーサーの精製のための低‐中圧液体クロマトグラフィーの使用
US10639608B2 (en) 2010-04-08 2020-05-05 Siemens Medical Solutions Usa, Inc. System, device and method for preparing tracers and transferring materials during radiosynthesis
DE102010036356A1 (de) * 2010-07-12 2012-01-12 Abx Advanced Biochemical Compounds Gmbh Vorrichtung zur Synthese radioaktiv markierter Verbindungen
US20120108858A1 (en) * 2010-10-28 2012-05-03 Maxim Kiselev Method and device for manufacturing of radiopharmaceuticals
BR112013015396B1 (pt) 2010-12-29 2021-11-03 Ge Healthcare Limited Método para a preparação de 18f para uso em uma reação de radiofluoração, reação de radiofluoração e cassete para a realização da reação de radiofluoração
US20130060017A1 (en) * 2011-07-15 2013-03-07 Cardinal Health 414, Llc Methods for synthesizing labeled compounds
GB201117785D0 (en) 2011-10-14 2011-11-30 Ge Healthcare Ltd Improved radiosynthesis method
GB201117786D0 (en) 2011-10-14 2011-11-30 Ge Healthcare Ltd Eluent vial
GB201120586D0 (en) * 2011-11-30 2012-01-11 Ge Healthcare Ltd Solid phase extraction neutralisation
HRP20250050T1 (hr) * 2013-11-13 2025-04-11 Ge Healthcare Limited Kaseta za dvostruku obradu za sintezu spojeva obilježenih radioizotopom 18f

Also Published As

Publication number Publication date
ES3005832T3 (en) 2025-03-17
PT3068747T (pt) 2025-01-24
HUE069777T2 (hu) 2025-04-28
FI3068747T3 (fi) 2024-12-30
KR20160085769A (ko) 2016-07-18
DE202015007501U1 (de) 2015-12-17
BE1022357A9 (fr) 2017-02-02
HRP20250050T1 (hr) 2025-04-11
US20160257622A1 (en) 2016-09-08
IL235650A0 (en) 2015-02-26
EP3068747B1 (en) 2024-10-30
WO2015071288A1 (en) 2015-05-21
BE1022357B1 (fr) 2016-03-24
CN113564722A (zh) 2021-10-29
PL3068747T3 (pl) 2025-03-10
JP6496726B2 (ja) 2019-04-03
JP2017503752A (ja) 2017-02-02
RS66442B1 (sr) 2025-02-28
KR102335535B1 (ko) 2021-12-08
CA2930479A1 (en) 2015-05-21
CA2930479C (en) 2023-03-28
DE202014010612U1 (de) 2016-04-19
CN104762666A (zh) 2015-07-08
US10584078B2 (en) 2020-03-10
IL235650B (en) 2019-10-31
EP3068747A1 (en) 2016-09-21

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