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DK2972238T3 - Anvendelse af raman-spektroskopi til monitorering af dyrkningsmedium - Google Patents

Anvendelse af raman-spektroskopi til monitorering af dyrkningsmedium Download PDF

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Publication number
DK2972238T3
DK2972238T3 DK14765091.5T DK14765091T DK2972238T3 DK 2972238 T3 DK2972238 T3 DK 2972238T3 DK 14765091 T DK14765091 T DK 14765091T DK 2972238 T3 DK2972238 T3 DK 2972238T3
Authority
DK
Denmark
Prior art keywords
application
culture medium
raman spectroscopy
monitoring culture
monitoring
Prior art date
Application number
DK14765091.5T
Other languages
English (en)
Inventor
Justin Moretto
Alex Doane
Brandon Berry
Original Assignee
Biogen Ma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51537857&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2972238(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Ma Inc filed Critical Biogen Ma Inc
Application granted granted Critical
Publication of DK2972238T3 publication Critical patent/DK2972238T3/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/04—Batch operation; multisample devices
    • G01N2201/0446—Multicell plate, sequential
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DK14765091.5T 2013-03-15 2014-03-14 Anvendelse af raman-spektroskopi til monitorering af dyrkningsmedium DK2972238T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361798187P 2013-03-15 2013-03-15
PCT/US2014/029633 WO2014144999A1 (en) 2013-03-15 2014-03-14 Use of raman spectroscopy to monitor culture medium

Publications (1)

Publication Number Publication Date
DK2972238T3 true DK2972238T3 (da) 2023-06-19

Family

ID=51537857

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14765091.5T DK2972238T3 (da) 2013-03-15 2014-03-14 Anvendelse af raman-spektroskopi til monitorering af dyrkningsmedium

Country Status (4)

Country Link
US (2) US11249026B2 (da)
EP (1) EP2972238B1 (da)
DK (1) DK2972238T3 (da)
WO (1) WO2014144999A1 (da)

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US9506867B2 (en) 2012-12-11 2016-11-29 Biogen Ma Inc. Spectroscopic analysis of nutrient materials for use in a cell culture process
WO2014144999A1 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Use of raman spectroscopy to monitor culture medium
EP3164481A4 (en) 2014-07-02 2018-03-21 Biogen MA Inc. Cross-scale modeling of bioreactor cultures using raman spectroscopy
US20180291329A1 (en) * 2015-05-29 2018-10-11 Biogen Ma Inc. Cell culture methods and systems
IL273549B2 (en) * 2017-10-06 2023-10-01 Lonza Ag Automated control of cell culture using Raman spectroscopy
CN118580927A (zh) * 2017-10-16 2024-09-03 里珍纳龙药品有限公司 灌注生物反应器及相关使用方法
US11627895B2 (en) * 2018-08-10 2023-04-18 Samsung Electronics Co., Ltd. Apparatus and method for estimating analyte concentration, and apparatus and method for generating analyte concentration estimation model
EA202092684A1 (ru) 2018-08-27 2021-03-11 Ридженерон Фармасьютикалз, Инк. Применение рамановской спектроскопии для последующей очистки
GB201820282D0 (en) * 2018-12-13 2019-01-30 Ge Healthcare Bio Sciences Ab Method for control of a bioprocess
US20220220430A1 (en) * 2019-05-23 2022-07-14 Bristol-Myers Squibb Company Methods of monitoring cell culture media
US11774287B2 (en) * 2019-05-28 2023-10-03 WuXi Biologics Ireland Limited Raman spectroscopy integrated perfusion cell culture system for monitoring and auto-controlling perfusion cell culture
GB201909082D0 (en) * 2019-06-25 2019-08-07 Ge Healthcare Bio Sciences Ab Methods for control of a bioprocess
CN110361373A (zh) * 2019-07-29 2019-10-22 西安石油大学 一种基于拉曼-近红外光谱融合技术快速检测甲醇汽油甲醇含量的方法
FR3122735B1 (fr) * 2021-05-04 2024-02-23 Centralesupelec Installation de détection d’au moins un paramètre caractéristique d’un milieu et procédé de détection d’au moins un tel paramètre caractéristique.
CN114441506B (zh) * 2022-04-08 2022-06-21 港湾之星健康生物(深圳)有限公司 量子磁光传感器
CN120655650B (zh) * 2025-08-20 2025-10-17 湖南大学 基于红外-拉曼图像恢复模型的细胞培养监测方法及系统

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US6350367B1 (en) 1996-03-01 2002-02-26 Orion Research, Inc. Calibration method using a stable and safe redox standard solution
WO1998041611A1 (en) 1997-03-20 1998-09-24 Regents Of The University Of Minnesota Process for the continuous culture of cells
US6574501B2 (en) 1998-07-13 2003-06-03 Childrens Hospital Los Angeles Assessing blood brain barrier dynamics or identifying or measuring selected substances or toxins in a subject by analyzing Raman spectrum signals of selected regions in the eye
US6608678B1 (en) 2000-10-19 2003-08-19 General Electric Company Situ determination of DPC and BPA in polycarbonate by Raman spectroscopy
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US20060281068A1 (en) 2005-06-09 2006-12-14 Chemimage Corp. Cytological methods for detecting a disease condition such as malignancy by Raman spectroscopic imaging
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GB201018628D0 (en) 2010-11-04 2010-12-22 Univ Nottingham Method, apparatus and software for identifying cells
US20120316446A1 (en) 2011-06-07 2012-12-13 Sinisa Vukelic Raman spectral analysis for disease detection and monitoring
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US10101209B2 (en) * 2012-04-30 2018-10-16 Finesse Solutions, Inc. Method and apparatus for quantifying solutions comprised of multiple analytes
US9506867B2 (en) 2012-12-11 2016-11-29 Biogen Ma Inc. Spectroscopic analysis of nutrient materials for use in a cell culture process
WO2014144999A1 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Use of raman spectroscopy to monitor culture medium
EP3164481A4 (en) 2014-07-02 2018-03-21 Biogen MA Inc. Cross-scale modeling of bioreactor cultures using raman spectroscopy
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US20180291329A1 (en) 2015-05-29 2018-10-11 Biogen Ma Inc. Cell culture methods and systems

Also Published As

Publication number Publication date
US20230175967A1 (en) 2023-06-08
EP2972238A4 (en) 2016-11-16
US11249026B2 (en) 2022-02-15
EP2972238A1 (en) 2016-01-20
EP2972238B1 (en) 2023-04-26
US20160025633A1 (en) 2016-01-28
US12372470B2 (en) 2025-07-29
WO2014144999A1 (en) 2014-09-18

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