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DK2952513T3 - Azolbenzenderivat - Google Patents

Azolbenzenderivat Download PDF

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Publication number
DK2952513T3
DK2952513T3 DK14746209.7T DK14746209T DK2952513T3 DK 2952513 T3 DK2952513 T3 DK 2952513T3 DK 14746209 T DK14746209 T DK 14746209T DK 2952513 T3 DK2952513 T3 DK 2952513T3
Authority
DK
Denmark
Prior art keywords
azolbenzender
derivative
azolbenzender derivative
Prior art date
Application number
DK14746209.7T
Other languages
English (en)
Inventor
Asahi Kawana
Chikashi Kanazawa
Yoshimasa Takahashi
Takashi Shirakura
Original Assignee
Teijin Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51262388&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2952513(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd
Application granted granted Critical
Publication of DK2952513T3 publication Critical patent/DK2952513T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/04Drugs for disorders of the urinary system for urolithiasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK14746209.7T 2013-01-31 2014-01-30 Azolbenzenderivat DK2952513T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013017167 2013-01-31
PCT/JP2014/052154 WO2014119681A1 (ja) 2013-01-31 2014-01-30 アゾールベンゼン誘導体

Publications (1)

Publication Number Publication Date
DK2952513T3 true DK2952513T3 (da) 2019-09-02

Family

ID=51262388

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14746209.7T DK2952513T3 (da) 2013-01-31 2014-01-30 Azolbenzenderivat

Country Status (36)

Country Link
US (1) US9388174B2 (da)
EP (1) EP2952513B1 (da)
JP (1) JP5734532B2 (da)
KR (1) KR102199258B1 (da)
CN (1) CN104968662B (da)
AR (1) AR095098A1 (da)
AU (1) AU2014213396B2 (da)
BR (1) BR112015018033B1 (da)
CA (1) CA2897928C (da)
CL (1) CL2015002117A1 (da)
CY (1) CY1122015T1 (da)
DK (1) DK2952513T3 (da)
ES (1) ES2744817T3 (da)
HR (1) HRP20191554T1 (da)
HU (1) HUE047028T2 (da)
IL (2) IL239940B (da)
LT (1) LT2952513T (da)
MA (1) MA38295B1 (da)
ME (1) ME03516B (da)
MX (1) MX364483B (da)
MY (1) MY181731A (da)
NZ (1) NZ709407A (da)
PE (1) PE20151329A1 (da)
PH (2) PH12015501640A1 (da)
PL (1) PL2952513T3 (da)
PT (1) PT2952513T (da)
RS (1) RS59371B1 (da)
RU (1) RU2641891C2 (da)
SA (1) SA515360829B1 (da)
SG (1) SG11201505993PA (da)
SI (1) SI2952513T1 (da)
SM (1) SMT201900577T1 (da)
TW (1) TWI606048B (da)
UA (1) UA117124C2 (da)
WO (1) WO2014119681A1 (da)
ZA (1) ZA201505240B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2953931T3 (pl) 2013-01-31 2017-09-29 Vertex Pharmaceuticals Incorporated Pirydonoamidy jako modulatory kanałów sodowych
SMT201800521T1 (it) 2013-12-13 2018-11-09 Vertex Pharma Profarmaci di piridonammidi utili come modulatori di canali del sodio
KR102259713B1 (ko) 2014-07-30 2021-06-01 데이진 화-마 가부시키가이샤 크산틴옥시다아제 저해약
SMT201900110T1 (it) 2014-07-30 2019-02-28 Teijin Pharma Ltd Derivato di benzene e azolo e relativo cristallo
BR112017001659A2 (pt) 2014-07-30 2018-01-30 Teijin Pharma Limited cristal, composição farmacêutica, inibidor de xantina oxidase, e, agente terapêutico ou profilático para uma ou mais doenças.
AR107661A1 (es) 2016-02-19 2018-05-23 Nat Univ Corp Tottori Univ Agente terapéutico o profiláctico para la demencia
JP6861726B2 (ja) 2016-11-28 2021-04-21 帝人ファーマ株式会社 糖尿病性腎症の治療薬または予防薬
WO2018213426A1 (en) 2017-05-16 2018-11-22 Vertex Pharmaceuticals Incorporated Deuterated pyridone amides and prodrugs thereof as modulators of sodium channels
JP2021512935A (ja) 2018-02-12 2021-05-20 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated 疼痛を処置する方法
PH12022551379A1 (en) 2019-12-06 2023-05-03 Vertex Pharma Substituted tetrahydrofurans as modulators of sodium channels
DK4347031T3 (da) 2021-06-04 2025-12-01 Vertex Pharma N-(hydroxyalkyl-(hetero)aryl)-tetrahydrofuran-carboxamider som modulatorer af natriumkanaler

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG86971A1 (en) 1990-11-30 2002-03-19 Teijin Ltd 2-arylthiazole derivatives and pharmaceutical composition thereof
JP3194964B2 (ja) 1995-04-07 2001-08-06 帝人株式会社 臓器または組織保護剤
CN1072669C (zh) * 1995-04-21 2001-10-10 纽罗研究公司 苯并咪唑化合物及其用作gabaa受体复合物调节器的用途
JP2002105067A (ja) 2000-09-28 2002-04-10 Teijin Ltd 2−フェニルチアゾール誘導体、およびそれを有効成分とする医薬組成物
EP1932833B1 (en) 2005-10-07 2012-08-01 Kissei Pharmaceutical Co., Ltd. Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same
WO2008126770A1 (ja) 2007-04-05 2008-10-23 Astellas Pharma Inc. トリアリールカルボン酸誘導体の製造方法
RU2515968C2 (ru) 2007-04-11 2014-05-20 Киссеи Фармасьютикал Ко., Лтд. 5-членное гетероциклическое соединение и его применение для лекарственных целей
WO2010018458A2 (en) 2008-08-12 2010-02-18 Crystalgenomics, Inc. Phenol derivatives and methods of use thereof
WO2010128163A2 (en) 2009-05-08 2010-11-11 Pike Pharma Gmbh Small molecule inhibitors of influenza a and b virus and respiratory syncytial virus replication
EP2536699A2 (en) 2010-02-19 2012-12-26 Cadila Healthcare Limited Substantially pure salts of febuxostat and processes for preparation thereof
WO2011139886A2 (en) 2010-04-29 2011-11-10 Dr. Reddy's Laboratories Ltd. Preparation of febuxostat

Also Published As

Publication number Publication date
PH12018500261A1 (en) 2018-09-10
SG11201505993PA (en) 2015-08-28
PL2952513T3 (pl) 2020-01-31
ZA201505240B (en) 2016-08-31
HRP20191554T1 (hr) 2019-11-29
PH12018500261B1 (en) 2018-09-10
BR112015018033B1 (pt) 2023-02-14
CN104968662B (zh) 2018-03-30
KR20150112955A (ko) 2015-10-07
CA2897928A1 (en) 2014-08-07
AU2014213396B2 (en) 2017-05-11
MX2015009655A (es) 2015-12-07
SA515360829B1 (ar) 2018-10-11
PE20151329A1 (es) 2015-10-12
UA117124C2 (uk) 2018-06-25
PH12015501640B1 (en) 2015-10-12
CY1122015T1 (el) 2020-10-14
RU2015132105A (ru) 2017-02-03
CA2897928C (en) 2021-02-16
AU2014213396A1 (en) 2015-07-23
SMT201900577T1 (it) 2019-11-13
IL259824A (en) 2018-07-31
ME03516B (me) 2020-04-20
JPWO2014119681A1 (ja) 2017-01-26
PH12015501640A1 (en) 2015-10-12
EP2952513B1 (en) 2019-07-10
MA38295A1 (fr) 2017-12-29
WO2014119681A1 (ja) 2014-08-07
MX364483B (es) 2019-04-26
NZ709407A (en) 2019-09-27
EP2952513A1 (en) 2015-12-09
CL2015002117A1 (es) 2015-10-30
IL239940A0 (en) 2015-08-31
AR095098A1 (es) 2015-09-30
BR112015018033A2 (pt) 2017-07-11
CN104968662A (zh) 2015-10-07
LT2952513T (lt) 2019-10-25
ES2744817T3 (es) 2020-02-26
TWI606048B (zh) 2017-11-21
EP2952513A4 (en) 2015-12-09
JP5734532B2 (ja) 2015-06-17
HUE047028T2 (hu) 2020-04-28
IL259824B (en) 2020-04-30
SI2952513T1 (sl) 2019-08-30
RS59371B1 (sr) 2019-11-29
PT2952513T (pt) 2019-09-27
BR112015018033A8 (pt) 2019-11-05
MA38295B1 (fr) 2018-04-30
RU2641891C2 (ru) 2018-01-23
US20150376174A1 (en) 2015-12-31
HK1215806A1 (zh) 2016-09-15
KR102199258B1 (ko) 2021-01-06
TW201443047A (zh) 2014-11-16
IL239940B (en) 2018-07-31
US9388174B2 (en) 2016-07-12
MY181731A (en) 2021-01-05

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