DK2819667T3 - Retinalderivater til anvendelse til forbedring af synsfunktionen - Google Patents
Retinalderivater til anvendelse til forbedring af synsfunktionen Download PDFInfo
- Publication number
- DK2819667T3 DK2819667T3 DK13760943.4T DK13760943T DK2819667T3 DK 2819667 T3 DK2819667 T3 DK 2819667T3 DK 13760943 T DK13760943 T DK 13760943T DK 2819667 T3 DK2819667 T3 DK 2819667T3
- Authority
- DK
- Denmark
- Prior art keywords
- improve
- vision function
- retinal derivatives
- retinal
- derivatives
- Prior art date
Links
- 150000003726 retinal derivatives Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261605729P | 2012-03-01 | 2012-03-01 | |
| US201261642212P | 2012-05-03 | 2012-05-03 | |
| US201261644360P | 2012-05-08 | 2012-05-08 | |
| PCT/CA2013/050155 WO2013134867A1 (en) | 2012-03-01 | 2013-03-01 | Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2819667T3 true DK2819667T3 (da) | 2020-03-30 |
Family
ID=49160185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13760943.4T DK2819667T3 (da) | 2012-03-01 | 2013-03-01 | Retinalderivater til anvendelse til forbedring af synsfunktionen |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20160296478A1 (da) |
| EP (1) | EP2819667B8 (da) |
| JP (3) | JP6576636B2 (da) |
| KR (1) | KR102133608B1 (da) |
| CN (2) | CN104470511A (da) |
| AU (3) | AU2013232697B2 (da) |
| BR (1) | BR112014021602A2 (da) |
| CA (1) | CA2865935C (da) |
| DK (1) | DK2819667T3 (da) |
| ES (1) | ES2780357T3 (da) |
| IL (1) | IL234306B (da) |
| MX (2) | MX370928B (da) |
| NZ (1) | NZ629267A (da) |
| PT (1) | PT2819667T (da) |
| RU (1) | RU2635536C2 (da) |
| WO (1) | WO2013134867A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201507819VA (en) | 2010-04-19 | 2015-10-29 | Quadra Logic Tech Inc | Therapeutic Regimen And Methods For Treating Or Ameliorating Visual Disorders Associated With An Endogenous Retinoid Deficiency |
| CA2865935C (en) | 2012-03-01 | 2021-12-14 | Qlt Inc. | Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency |
| WO2015164419A1 (en) * | 2014-04-22 | 2015-10-29 | Acucela Inc. | Pupillometric assessment of retinal pharmacodynamics and responses therefrom |
| US12029715B2 (en) * | 2015-05-08 | 2024-07-09 | University Of Debrecen | Precursor compounds for providing retinoids of the vitamin A5 pathway and uses thereof |
| EP3294711B1 (en) * | 2015-05-08 | 2020-01-08 | University of Debrecen | Stereoselective synthesis of 9-cis-13,14-dihydroretinoic acid and its ethyl esters |
| JP7266247B6 (ja) | 2016-11-17 | 2024-02-15 | ユニバーシティー オブ デブレツェン | ビタミンa5経路のレチノイド類を提供するための前駆体化合物及びその使用 |
| RU186184U1 (ru) * | 2018-06-06 | 2019-01-11 | Федеральное государственное бюджетное учреждение "33 Центральный научно-исследовательский испытательный институт" Министерства обороны Российской Федерации | Устройство для оценки углов обзора и поля зрения испытателей в противогазе |
| WO2021252421A1 (en) * | 2020-06-09 | 2021-12-16 | Retinagenix Holdings Llc | Methods of treating visual disorders using daily low dosing of a retinoid compound |
| WO2024110625A1 (en) | 2022-11-24 | 2024-05-30 | Universität Bern | Cralbp based therapeutics for retinal disorders |
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| US3196078A (en) | 1962-01-30 | 1965-07-20 | Ortho Pharma Corp | Process for combating retinits pigmentosa |
| US3517067A (en) | 1964-02-11 | 1970-06-23 | Eastman Kodak Co | Syntheses of quaternary phosphonium salts |
| DE2300107C2 (de) | 1973-01-03 | 1982-03-11 | Basf Ag, 6700 Ludwigshafen | Vitamin A-Säureanilid-4-carbonsäureäthylester, Verfahren zu seiner Herstellung und diesen enthaltende Zubereitungen |
| CH590222A5 (da) | 1973-08-21 | 1977-07-29 | Hoffmann La Roche | |
| US4022913A (en) | 1973-09-13 | 1977-05-10 | Hoffmann-La Roche Inc. | High potency vitamin A compositions |
| DE2456959A1 (de) | 1974-12-03 | 1976-06-16 | Basf Ag | 4-(e)- und 4-(z)-7-methyl-9-(2,6,6trimethyl-1-cyclohexen-1-yl)-nona-2,4,6,8tetraencarbonsaeure, ihre derivate und diese enthaltende zubereitungen |
| CA1198859A (en) | 1982-04-21 | 1986-01-07 | Chester L. O'neal | Disposable toothbrush with cap |
| US4532133A (en) | 1983-05-24 | 1985-07-30 | Basf Wyandotte Corporation | Low temperature stable, emulsifiable vitamin A concentrates |
| CA1282326C (en) | 1984-12-14 | 1991-04-02 | Paul J. Jarosz | Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient |
| JPS61275266A (ja) | 1985-05-28 | 1986-12-05 | Taisho Pharmaceut Co Ltd | レチノイド誘導体 |
| CZ282548B6 (cs) | 1992-01-22 | 1997-08-13 | F. Hoffmann-La Roche Ag | Farmaceutický přípravek |
| US5310764A (en) | 1992-05-08 | 1994-05-10 | Steven Baranowitz | Treatment of age related macular degeneration with beta-carotene |
| JPH06340525A (ja) | 1993-06-02 | 1994-12-13 | Lion Corp | 安定な低眼刺激性ビタミンa類可溶化点眼剤 |
| WO1995026734A1 (en) | 1994-04-04 | 1995-10-12 | Freeman William R | Use of phosphonylmethoxyalkyl nucleosides for the treatment of raised intraocular pressure |
| RU2106843C1 (ru) | 1994-06-29 | 1998-03-20 | Красноярская государственная медицинская академия | Способ лечения близорукости |
| JPH08198746A (ja) | 1995-01-18 | 1996-08-06 | Lion Corp | 可溶化点眼剤 |
| US5837728A (en) | 1995-01-27 | 1998-11-17 | Molecular Design International | 9-cis retinoic acid esters and amides and uses thereof |
| US5489611A (en) | 1995-02-10 | 1996-02-06 | Warner-Lambert Company | Method for lowering plasma levels of lipoprotein (a) |
| US5620970A (en) | 1995-06-05 | 1997-04-15 | Alcon Laboratories, Inc. | Topical ophthalmic carbonic anhydrase inhibitor formulations |
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| US6391924B1 (en) | 1997-12-10 | 2002-05-21 | Hampar Karageozian | Taurine derivatives useable in the treatment of ophthalmic disorders |
| US6552009B2 (en) | 1998-07-16 | 2003-04-22 | Gentrix Llc | Compositions and methods of treating abnormal cell proliferation |
| US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| US6372463B1 (en) | 1999-05-06 | 2002-04-16 | The President & Fellows Of Harvard College | Mutations in nucleic acid molecules encoding 11-CIS retinol dehydrogenase, the mutated proteins, and uses thereof |
| US6300328B1 (en) | 1999-08-06 | 2001-10-09 | Alcon Universal Ltd. | Selective inhibitors of adenosine monophosphate deaminase for the treatment of optic nerve and retinal damage |
| US20020028849A1 (en) | 2000-04-18 | 2002-03-07 | Godkin James D. | Use of retinol in assisted-reproduction protocols |
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| JP4210115B2 (ja) | 2001-01-11 | 2009-01-14 | チェビジェン・インコーポレイテッド | 新規レチノール誘導体および製造方法および用途 |
| WO2002082904A2 (en) | 2001-04-13 | 2002-10-24 | The Trustees Of The University Of Pennsylvania | Method of treating or retarding the development of blindness |
| ITMI20012366A1 (it) | 2001-11-09 | 2003-05-09 | Farmatron Ltd | Sistemi terapeutici stabilizzati a rilascio immediato e/o modificato per la somministrazione orale di principi attivi e/o eccipienti e/o ali |
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| WO2006039551A2 (en) * | 2004-09-30 | 2006-04-13 | The Regents Of The University Of California | Local administration of retinoids to treat deficiencies in dark adaptation |
| US20060177392A1 (en) | 2005-02-10 | 2006-08-10 | William Walden | Oil-based composition for acne |
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| CN101605754B (zh) | 2007-01-15 | 2015-09-16 | 于崇曦 | 具有快速皮肤穿透速度的带正电荷的水溶性的维生素a酸类和类维生素a酸化合物的前药 |
| US8877809B2 (en) | 2007-09-12 | 2014-11-04 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for treating macular degeneration |
| NZ587376A (en) | 2008-02-11 | 2012-06-29 | Univ Washington | Methods for the treatment and prevention of age-related retinal dysfunction |
| CA2774168C (en) * | 2009-09-15 | 2021-02-23 | Ronald Erwin Boch | Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle |
| FR2955459B1 (fr) | 2010-01-28 | 2013-11-22 | Polaris | Composition huileuse riche en monoglycerides de dha |
| SG10201507819VA (en) | 2010-04-19 | 2015-10-29 | Quadra Logic Tech Inc | Therapeutic Regimen And Methods For Treating Or Ameliorating Visual Disorders Associated With An Endogenous Retinoid Deficiency |
| CA2865935C (en) | 2012-03-01 | 2021-12-14 | Qlt Inc. | Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency |
| US20150038582A1 (en) | 2012-03-01 | 2015-02-05 | Qlt Inc. | Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency |
| JP6340525B2 (ja) | 2013-11-25 | 2018-06-13 | 株式会社デンソー | モータアクチュエータ |
-
2013
- 2013-03-01 CA CA2865935A patent/CA2865935C/en active Active
- 2013-03-01 EP EP13760943.4A patent/EP2819667B8/en active Active
- 2013-03-01 ES ES13760943T patent/ES2780357T3/es active Active
- 2013-03-01 MX MX2014010457A patent/MX370928B/es active IP Right Grant
- 2013-03-01 JP JP2014559050A patent/JP6576636B2/ja active Active
- 2013-03-01 NZ NZ629267A patent/NZ629267A/en not_active IP Right Cessation
- 2013-03-01 BR BR112014021602A patent/BR112014021602A2/pt not_active Application Discontinuation
- 2013-03-01 KR KR1020147027749A patent/KR102133608B1/ko active Active
- 2013-03-01 PT PT137609434T patent/PT2819667T/pt unknown
- 2013-03-01 CN CN201380022484.3A patent/CN104470511A/zh active Pending
- 2013-03-01 WO PCT/CA2013/050155 patent/WO2013134867A1/en not_active Ceased
- 2013-03-01 AU AU2013232697A patent/AU2013232697B2/en active Active
- 2013-03-01 DK DK13760943.4T patent/DK2819667T3/da active
- 2013-03-01 CN CN201811054761.XA patent/CN109248163A/zh active Pending
- 2013-03-01 MX MX2020000225A patent/MX389866B/es unknown
- 2013-03-01 RU RU2014139666A patent/RU2635536C2/ru active
-
2014
- 2014-08-26 IL IL234306A patent/IL234306B/en unknown
-
2016
- 2016-04-11 US US15/096,048 patent/US20160296478A1/en not_active Abandoned
-
2017
- 2017-08-15 JP JP2017156807A patent/JP2017197588A/ja active Pending
-
2018
- 2018-01-18 AU AU2018200415A patent/AU2018200415B2/en not_active Expired - Fee Related
- 2018-06-11 US US16/005,155 patent/US10828267B2/en active Active
-
2019
- 2019-12-20 AU AU2019283995A patent/AU2019283995B2/en not_active Ceased
-
2020
- 2020-02-10 JP JP2020020391A patent/JP2020073597A/ja active Pending
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