DK2854907T3 - Drivmekanisme til en lægemiddeladministrationsanordning og lægemiddeladministrationsanordning - Google Patents
Drivmekanisme til en lægemiddeladministrationsanordning og lægemiddeladministrationsanordning Download PDFInfo
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- DK2854907T3 DK2854907T3 DK13725368.8T DK13725368T DK2854907T3 DK 2854907 T3 DK2854907 T3 DK 2854907T3 DK 13725368 T DK13725368 T DK 13725368T DK 2854907 T3 DK2854907 T3 DK 2854907T3
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- piston rod
- drive
- housing
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- 229940055729 papain Drugs 0.000 description 1
- 235000019834 papain Nutrition 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 description 1
- 230000002797 proteolythic effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 229960004532 somatropin Drugs 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 241001223854 teleost fish Species 0.000 description 1
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- BENFXAYNYRLAIU-QSVFAHTRSA-N terlipressin Chemical compound NCCCC[C@@H](C(=O)NCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC=2C=CC(O)=CC=2)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)CN)CSSC1 BENFXAYNYRLAIU-QSVFAHTRSA-N 0.000 description 1
- CIJQTPFWFXOSEO-NDMITSJXSA-J tetrasodium;(2r,3r,4s)-2-[(2r,3s,4r,5r,6s)-5-acetamido-6-[(1r,2r,3r,4r)-4-[(2r,3s,4r,5r,6r)-5-acetamido-6-[(4r,5r,6r)-2-carboxylato-4,5-dihydroxy-6-[[(1r,3r,4r,5r)-3-hydroxy-4-(sulfonatoamino)-6,8-dioxabicyclo[3.2.1]octan-2-yl]oxy]oxan-3-yl]oxy-2-(hydroxy Chemical compound [Na+].[Na+].[Na+].[Na+].O([C@@H]1[C@@H](COS(O)(=O)=O)O[C@@H]([C@@H]([C@H]1O)NC(C)=O)O[C@@H]1C(C[C@H]([C@@H]([C@H]1O)O)O[C@@H]1[C@@H](CO)O[C@H](OC2C(O[C@@H](OC3[C@@H]([C@@H](NS([O-])(=O)=O)[C@@H]4OC[C@H]3O4)O)[C@H](O)[C@H]2O)C([O-])=O)[C@H](NC(C)=O)[C@H]1C)C([O-])=O)[C@@H]1OC(C([O-])=O)=C[C@H](O)[C@H]1O CIJQTPFWFXOSEO-NDMITSJXSA-J 0.000 description 1
- 229960004824 triptorelin Drugs 0.000 description 1
- VXKHXGOKWPXYNA-PGBVPBMZSA-N triptorelin Chemical compound C([C@@H](C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 VXKHXGOKWPXYNA-PGBVPBMZSA-N 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
- A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Claims (8)
1. Drivmekanisme til en lægemiddeladministrationsanordning (1) , som omfatter: - en stempelstang (11), der forskydes i distal retning (25) til dispensering af en dosis og i proksimal retning (26) til nulstilling, og - en elastisk del (20), der virker på stempelstangen (11) under nulstilling og tenderer mod at begrænse bevægelsen af stempelstangen (11) i den proksimale retning (26), hvor - den elastiske del (20) er en påvirkningsdel (20) beregnet til automatisk nulstilling, hvor drivmekanismen yderligere omfatter: en roterbar drivdel (16), der er i gevindindgreb med stempelstangen (11), - et hus (2) - en låsemøtrik (13), der er frigørligt rotationslåst til huset (2) og i gevindindgreb med stempelstangen (11), og - en patronholder (3), der kan påmonteres eller afmonteres, idet låsemøtrikken (13) er rotationslåst til huset (2), når patronholderen (3) er påmonteret, og ikke er rotationslåst til huset (2), når patronholderen (3) er afmonteret, der er kendetegnet ved, at - drivdelen (16) roterer under dispensering af dosen, hvor påvirkningsdelen belastes ved rotation af drivdelen (16) under dispensering af dosen og tenderer mod at rotere stempelstangen (11) i forhold til drivdelen (16) på en sådan måde, at stempelstangen (11) skrues ind i drivdelen (16) og derved fremføres i den proksimale retning (26), indtil påvirkningsdelen (20) er relakseret, og bevægelsen af stempelstangen (11) i den proksimale retning (26) er stoppet, - påvirkningsdelen (20) er i klinkeindgreb med låsemøtrikken (13) og med drivdelen (16), således at påvirkningsdelen (20) belastes, når drivdelen (16) roterer i forhold til huset (2) under dispensering af dosen, og - påvirkningsdelen (20) relakserer, når rotationslåsningen af låsemøtrikken (13) fjernes, hvilket resulterer i en rotation af låsemøtrikken (13) og en tilsvarende rotation af stempelstangen (11) i forhold til drivdelen (16).
2. Drivmekanisme ifølge krav 1, hvor påvirkningsdelen (20) er en spiralformet fjeder, der er anbragt coaksialt med stempelstangen (11).
3. Drivmekanisme ifølge krav 1 eller 2, hvor den elastiske del (20) belastes ved rotation af drivdelen (16) i forhold til huset (2) .
4. Drivmekanisme ifølge et af kravene 1 til 3, hvor den elastiske del (20) er beregnet til at drive stempelstangen (11) i den distale retning (25) til en start- eller foraktiveret position.
5. Lægemiddeladministrationsanordning (1), der omfatter en drivmekanisme ifølge et af kravene 1 til 4.
6. Lægemiddeladministrationsanordning (1) ifølge krav 5, hvor den aftagelige patronholder (3) er beregnet til isætning af en patron (8).
7. Lægemiddeladministrationsanordning (1) ifølge krav 5 eller 6, hvor anordningen (1) er en pentype anordning.
8. Lægemiddeladministrationsanordning (1) ifølge et af kravene 5 til 7, hvor anordningen (1) er beregnet til administration af faste doser.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12170066 | 2012-05-30 | ||
| PCT/EP2013/060911 WO2013178599A1 (en) | 2012-05-30 | 2013-05-28 | Drive mechanism for a drug delivery device and drug delivery device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2854907T3 true DK2854907T3 (da) | 2019-04-23 |
Family
ID=48534390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13725368.8T DK2854907T3 (da) | 2012-05-30 | 2013-05-28 | Drivmekanisme til en lægemiddeladministrationsanordning og lægemiddeladministrationsanordning |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9700679B2 (da) |
| EP (1) | EP2854907B1 (da) |
| JP (1) | JP6310451B2 (da) |
| CN (1) | CN104349807B (da) |
| DK (1) | DK2854907T3 (da) |
| HK (1) | HK1203865A1 (da) |
| TR (1) | TR201904548T4 (da) |
| WO (1) | WO2013178599A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6342815B2 (ja) * | 2013-01-15 | 2018-06-13 | テルモ株式会社 | 液体投与具 |
| EP3071265B1 (en) * | 2013-11-22 | 2023-04-26 | Sanofi-Aventis Deutschland GmbH | Spring assisted drug delivery device |
| TW201726197A (zh) | 2015-11-27 | 2017-08-01 | 賽諾菲阿凡提斯德意志有限公司 | 注射裝置（四） |
| GB201616709D0 (en) * | 2016-09-30 | 2016-11-16 | Owen Mumford Ltd | Injection device |
| GB2556091A (en) * | 2016-11-18 | 2018-05-23 | Owen Mumford Ltd | Medicament delivery device and system |
| WO2018166985A1 (en) * | 2017-03-13 | 2018-09-20 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
| US11612698B2 (en) * | 2017-08-31 | 2023-03-28 | Eli Lilly And Company | Dose detection with piezoelectric sensing for a medication delivery device |
| EP3708206A1 (de) * | 2019-03-15 | 2020-09-16 | Tecpharma Licensing AG | Dosiereinrichtung für eine injektionsvorrichtung |
| WO2025153305A1 (en) * | 2024-01-19 | 2025-07-24 | Shl Medical Ag | Medicament delivery assembly with end of delivery signaling |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6277099B1 (en) | 1999-08-06 | 2001-08-21 | Becton, Dickinson And Company | Medication delivery pen |
| CA2689020C (en) * | 2001-05-16 | 2011-11-08 | Eli Lilly And Company | Medication injector apparatus with drive assembly that facilitates reset |
| WO2006058061A1 (en) * | 2004-11-24 | 2006-06-01 | Becton Dickinson And Company | Automatic reconstitution injector device |
| WO2009097934A1 (en) | 2008-02-05 | 2009-08-13 | Shl Group Ab | Injection device with pre-activation means |
| GB2461694A (en) * | 2008-07-08 | 2010-01-13 | Weston Terence E | Side-loaded pen injector |
| EP2196232A1 (en) | 2008-12-12 | 2010-06-16 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for a medication delivery device and medication delivery device |
| BRPI1012730A2 (pt) * | 2009-03-31 | 2016-05-03 | Sanofi Aventis Deutschland | dispositivo de distribuição de fármaco |
| CA2801635A1 (en) | 2010-06-11 | 2011-12-15 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
-
2013
- 2013-05-28 EP EP13725368.8A patent/EP2854907B1/en not_active Not-in-force
- 2013-05-28 WO PCT/EP2013/060911 patent/WO2013178599A1/en not_active Ceased
- 2013-05-28 JP JP2015514453A patent/JP6310451B2/ja not_active Expired - Fee Related
- 2013-05-28 TR TR2019/04548T patent/TR201904548T4/tr unknown
- 2013-05-28 DK DK13725368.8T patent/DK2854907T3/da active
- 2013-05-28 US US14/401,942 patent/US9700679B2/en not_active Expired - Fee Related
- 2013-05-28 CN CN201380026645.6A patent/CN104349807B/zh not_active Expired - Fee Related
- 2013-05-28 HK HK15104690.8A patent/HK1203865A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013178599A1 (en) | 2013-12-05 |
| US20150088079A1 (en) | 2015-03-26 |
| HK1203865A1 (en) | 2015-11-06 |
| JP6310451B2 (ja) | 2018-04-11 |
| TR201904548T4 (tr) | 2019-04-22 |
| JP2015517857A (ja) | 2015-06-25 |
| EP2854907A1 (en) | 2015-04-08 |
| US9700679B2 (en) | 2017-07-11 |
| CN104349807A (zh) | 2015-02-11 |
| EP2854907B1 (en) | 2019-01-16 |
| CN104349807B (zh) | 2017-10-27 |
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