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DK2771696T3 - Fremgangsmåder med anvendelse af metabolitpaneler til diagnosticering og differentiering af neonatal encefalopati - Google Patents

Fremgangsmåder med anvendelse af metabolitpaneler til diagnosticering og differentiering af neonatal encefalopati Download PDF

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Publication number
DK2771696T3
DK2771696T3 DK12778117.7T DK12778117T DK2771696T3 DK 2771696 T3 DK2771696 T3 DK 2771696T3 DK 12778117 T DK12778117 T DK 12778117T DK 2771696 T3 DK2771696 T3 DK 2771696T3
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DK
Denmark
Prior art keywords
differentiation
diagnosis
methods
neonatal encephalopathy
metabolite panels
Prior art date
Application number
DK12778117.7T
Other languages
English (en)
Inventor
David Enot
Matthias Keller
Original Assignee
Infandx Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infandx Ag filed Critical Infandx Ag
Application granted granted Critical
Publication of DK2771696T3 publication Critical patent/DK2771696T3/da

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/38Pediatrics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/70Machine learning, data mining or chemometrics

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK12778117.7T 2011-10-25 2012-10-25 Fremgangsmåder med anvendelse af metabolitpaneler til diagnosticering og differentiering af neonatal encefalopati DK2771696T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11008563.6A EP2587264A1 (en) 2011-10-25 2011-10-25 Method and use of metabolites for the diagnosis and differentiation of neonatal encephalopathy
PCT/EP2012/071174 WO2013060788A2 (en) 2011-10-25 2012-10-25 Method and use of metabolites for the diagnosis and differentiation of neonatal encephalopathy

Publications (1)

Publication Number Publication Date
DK2771696T3 true DK2771696T3 (da) 2022-10-03

Family

ID=47074734

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12778117.7T DK2771696T3 (da) 2011-10-25 2012-10-25 Fremgangsmåder med anvendelse af metabolitpaneler til diagnosticering og differentiering af neonatal encefalopati

Country Status (6)

Country Link
US (1) US10514383B2 (da)
EP (2) EP2587264A1 (da)
CA (1) CA2886644A1 (da)
DK (1) DK2771696T3 (da)
ES (1) ES2927921T3 (da)
WO (1) WO2013060788A2 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2587264A1 (en) 2011-10-25 2013-05-01 InfanDx AG Method and use of metabolites for the diagnosis and differentiation of neonatal encephalopathy
US11096619B2 (en) * 2013-07-12 2021-08-24 Innara Health, Inc. Neural analysis and treatment system
WO2016007762A1 (en) 2014-07-09 2016-01-14 Duke University Compositions and methods for the repair of myelin
RU2568914C1 (ru) * 2014-07-31 2015-11-20 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский институт акушерства и педиатрии" Министерства здравоохранения Российской Федерации Способ прогнозирования перинатального поражения цнс у недоношенных новорожденных
WO2016149808A1 (en) * 2015-03-20 2016-09-29 London Health Sciences Centre Research Inc. Metabolomics profiling of central nervous system injury
AU2017305520B2 (en) * 2016-08-04 2022-07-28 The General Hospital Corporation System and method for detecting acute brain function impairment
WO2018115427A1 (en) * 2016-12-23 2018-06-28 Pangratz Fuehrer Susanne Alpha-b crystallin in the diagnosis of neonatal brain damage
EP4537847A3 (en) 2017-01-13 2025-07-30 Duke University Compositions and methods for the treatment of myelin related and inflammation related diseases or disorders
EP3546938A1 (en) * 2018-03-30 2019-10-02 Université d'Angers Metabolic signature and use thereof for the diagnosis of glaucoma
CN114839298B (zh) * 2019-12-28 2024-06-07 中精普康(北京)医药科技有限公司 一种用于检测结直肠癌或腺瘤的生物标志物及其方法
WO2022213201A1 (en) * 2021-04-09 2022-10-13 Uti Limited Partnership Apparatus and methodologies for detection, diagnosis, and prognosis of brain injury
CN119534676B (zh) * 2024-10-15 2025-08-15 中日友好医院(中日友好临床医学研究所) 代谢标志物在制备监测pb神经毒性产品中的应用及制品

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1875401T3 (da) 2005-06-30 2014-04-07 Biocrates Life Sciences Ag Indretning til kvantitativ analyse af en metabolitprofil
EP2249161B1 (en) 2009-05-05 2020-05-13 InfanDx AG Method of diagnosing asphyxia
EP2284540A1 (en) 2009-07-31 2011-02-16 BIOCRATES Life Sciences AG Method of diagnosing organ failure
EP2587264A1 (en) 2011-10-25 2013-05-01 InfanDx AG Method and use of metabolites for the diagnosis and differentiation of neonatal encephalopathy

Also Published As

Publication number Publication date
WO2013060788A2 (en) 2013-05-02
EP2587264A1 (en) 2013-05-01
CA2886644A1 (en) 2013-05-02
US10514383B2 (en) 2019-12-24
EP2771696A2 (en) 2014-09-03
ES2927921T3 (es) 2022-11-14
US20140308687A1 (en) 2014-10-16
WO2013060788A3 (en) 2013-07-25
EP2771696B1 (en) 2022-09-14

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