DK2433637T5 - Anvendelse af quinazolin derivater til neurodegenerative sygdomme - Google Patents
Anvendelse af quinazolin derivater til neurodegenerative sygdomme Download PDFInfo
- Publication number
- DK2433637T5 DK2433637T5 DK10732398.2T DK10732398T DK2433637T5 DK 2433637 T5 DK2433637 T5 DK 2433637T5 DK 10732398 T DK10732398 T DK 10732398T DK 2433637 T5 DK2433637 T5 DK 2433637T5
- Authority
- DK
- Denmark
- Prior art keywords
- neurodegenerative diseases
- quinazoline derivatives
- quinazoline
- derivatives
- neurodegenerative
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200930189A ES2353093B1 (es) | 2009-05-20 | 2009-05-20 | Uso de derivados de quinazolinas y sus composiciones farmacéuticas en enfermedades neurodegenerativas. |
| PCT/ES2010/070338 WO2010133742A1 (es) | 2009-05-20 | 2010-05-20 | Uso de derivados de quinazolinas en enfermedades neurodegenerativas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK2433637T3 DK2433637T3 (da) | 2014-08-18 |
| DK2433637T5 true DK2433637T5 (da) | 2015-08-31 |
Family
ID=42732572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10732398.2T DK2433637T5 (da) | 2009-05-20 | 2010-05-20 | Anvendelse af quinazolin derivater til neurodegenerative sygdomme |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9192610B2 (da) |
| EP (1) | EP2433637B9 (da) |
| JP (1) | JP5563068B2 (da) |
| AU (1) | AU2010251044B2 (da) |
| DK (1) | DK2433637T5 (da) |
| ES (2) | ES2353093B1 (da) |
| PL (1) | PL2433637T3 (da) |
| PT (1) | PT2433637E (da) |
| SI (1) | SI2433637T1 (da) |
| WO (1) | WO2010133742A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5236664B2 (ja) | 2007-02-01 | 2013-07-17 | レスバーロジックス コーポレイション | 心血管疾患を予防および治療するための化合物 |
| MX392179B (es) | 2009-03-18 | 2025-03-21 | Resverlogix Corp | Nuevos agentes anti-inflamatorios. |
| JP6903585B2 (ja) | 2015-03-13 | 2021-07-14 | レスバーロジックス コーポレイション | 補体関連疾患の治療のための組成物および治療方法 |
| ES2544519B1 (es) * | 2015-05-22 | 2016-03-04 | Consejo Superior De Investigaciones Científicas (Csic) | Quinazolinas S-sustituidas y sus aplicaciones terapéuticas para el tratamiento de enfermedades mediadas por PDE7 |
| KR20180019234A (ko) | 2015-06-26 | 2018-02-23 | 다케다 야쿠힌 고교 가부시키가이샤 | 콜린성 무스카린 m1 수용체의 조절제로서의 2,3-디히드로-4h-1,3-벤족사진-4-온 유도체 |
| JP6740354B2 (ja) * | 2015-10-05 | 2020-08-12 | ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク | オートファジーの流れ及びホスホリパーゼｄ及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法 |
| US10548899B2 (en) | 2015-10-20 | 2020-02-04 | Takeda Pharmaceutical Company Limited | Quinazolinone and benzotriazinone compounds with cholinergic muscarinin M1 receptor positive allosteric modulator activity |
| WO2021050913A1 (en) * | 2019-09-12 | 2021-03-18 | Disarm Therapeutics, Inc. | Inhibitors of sarm1 |
| KR20250048344A (ko) | 2022-08-18 | 2025-04-08 | 미토디큐어 게엠베하 | 만성 피로, 탈진 및/또는 운동 불내성과 연관된 질환의 치료 및 예방을 위한 포스포디에스테라제-7 억제 활성을 갖는 치료제의 용도 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07107056B2 (ja) * | 1987-01-30 | 1995-11-15 | 日清製粉株式会社 | ４（３ｈ）−キナゾリノン誘導体、その製造方法およびそれを有効成分とする抗潰瘍剤 |
| FR2828693B1 (fr) * | 2001-08-14 | 2004-06-18 | Exonhit Therapeutics Sa | Nouvelle cible moleculaire de la neurotoxicite |
| WO2005051974A2 (en) * | 2003-06-09 | 2005-06-09 | The Regents Of The University Of California | Novel molecules for regulating cell death |
| ES2308916B1 (es) * | 2007-03-22 | 2009-10-29 | Consejo Superior De Investigaciones Cientificas | Compuesto inhibidor dual de las enzimas pde7 y/o pde4, composiciones farmaceuticas y sus aplicaciones. |
| AU2008230710B2 (en) | 2007-03-27 | 2014-04-10 | Omeros Corporation | The use of PDE7 inhibitors for the treatment of movement disorders |
| US20100179158A1 (en) * | 2007-04-20 | 2010-07-15 | Hoffman Charles S | Inhibitors of cyclic amp phosphodiesterases |
-
2009
- 2009-05-20 ES ES200930189A patent/ES2353093B1/es not_active Expired - Fee Related
-
2010
- 2010-05-20 PL PL10732398T patent/PL2433637T3/pl unknown
- 2010-05-20 DK DK10732398.2T patent/DK2433637T5/da active
- 2010-05-20 AU AU2010251044A patent/AU2010251044B2/en not_active Ceased
- 2010-05-20 JP JP2012511311A patent/JP5563068B2/ja not_active Expired - Fee Related
- 2010-05-20 EP EP10732398.2A patent/EP2433637B9/en active Active
- 2010-05-20 PT PT107323982T patent/PT2433637E/pt unknown
- 2010-05-20 US US13/321,046 patent/US9192610B2/en not_active Expired - Fee Related
- 2010-05-20 ES ES10732398.2T patent/ES2498828T3/es active Active
- 2010-05-20 WO PCT/ES2010/070338 patent/WO2010133742A1/es not_active Ceased
- 2010-05-20 SI SI201030690T patent/SI2433637T1/sl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI2433637T1 (sl) | 2014-09-30 |
| ES2353093A1 (es) | 2011-02-25 |
| WO2010133742A1 (es) | 2010-11-25 |
| JP5563068B2 (ja) | 2014-07-30 |
| PL2433637T3 (pl) | 2014-12-31 |
| US9192610B2 (en) | 2015-11-24 |
| ES2498828T3 (es) | 2014-09-25 |
| JP2012527434A (ja) | 2012-11-08 |
| US20120129877A1 (en) | 2012-05-24 |
| AU2010251044A1 (en) | 2012-03-01 |
| ES2353093B1 (es) | 2012-01-03 |
| AU2010251044B2 (en) | 2014-08-28 |
| EP2433637B1 (en) | 2014-06-11 |
| EP2433637B9 (en) | 2015-06-10 |
| EP2433637A1 (en) | 2012-03-28 |
| PT2433637E (pt) | 2014-09-09 |
| DK2433637T3 (da) | 2014-08-18 |
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