DK2114531T3 - Punktpropper og fremgangsmåder til indgivelse af terapeutiske midler - Google Patents
Punktpropper og fremgangsmåder til indgivelse af terapeutiske midlerInfo
- Publication number
- DK2114531T3 DK2114531T3 DK08728546.6T DK08728546T DK2114531T3 DK 2114531 T3 DK2114531 T3 DK 2114531T3 DK 08728546 T DK08728546 T DK 08728546T DK 2114531 T3 DK2114531 T3 DK 2114531T3
- Authority
- DK
- Denmark
- Prior art keywords
- plugs
- dot
- methods
- therapeutic agents
- administering therapeutic
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Prostheses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89859907P | 2007-01-31 | 2007-01-31 | |
| PCT/US2008/052439 WO2008094989A2 (en) | 2007-01-31 | 2008-01-30 | Punctal plugs and methods of delivering therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2114531T3 true DK2114531T3 (da) | 2012-07-30 |
Family
ID=39313204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK08728546.6T DK2114531T3 (da) | 2007-01-31 | 2008-01-30 | Punktpropper og fremgangsmåder til indgivelse af terapeutiske midler |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8753666B2 (da) |
| EP (1) | EP2114531B1 (da) |
| JP (1) | JP2010517630A (da) |
| KR (1) | KR20090104099A (da) |
| CN (1) | CN101600476B (da) |
| AR (1) | AR065235A1 (da) |
| AU (1) | AU2008210541B2 (da) |
| BR (1) | BRPI0807340A2 (da) |
| CA (1) | CA2674913A1 (da) |
| CL (1) | CL2008000306A1 (da) |
| CY (1) | CY1113075T1 (da) |
| DK (1) | DK2114531T3 (da) |
| ES (1) | ES2390991T3 (da) |
| HR (1) | HRP20120608T1 (da) |
| MX (1) | MX2009007394A (da) |
| PL (1) | PL2114531T3 (da) |
| PT (1) | PT2114531E (da) |
| RU (1) | RU2459646C2 (da) |
| SI (1) | SI2114531T1 (da) |
| TW (1) | TW200838485A (da) |
| UY (1) | UY30883A1 (da) |
| WO (1) | WO2008094989A2 (da) |
| ZA (1) | ZA200904713B (da) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050232972A1 (en) | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
| CN101052435B (zh) | 2004-07-02 | 2010-12-08 | Qlt塞子传递公司 | 治疗介质递送装置 |
| EP1998829B1 (en) | 2006-03-14 | 2011-02-09 | University Of Southern California | Mems device for delivery of therapeutic agents |
| ES2640458T3 (es) | 2006-03-31 | 2017-11-03 | Mati Therapeutics Inc. | Implantes del sistema de drenaje nasolagrimal para terapia medicamentosa |
| EP3372205A1 (en) | 2007-09-07 | 2018-09-12 | Mati Therapeutics Inc. | Lacrimal implant detection |
| NZ598483A (en) | 2007-09-07 | 2013-08-30 | Quadra Logic Tech Inc | Drug cores for sustained release of therapeutic agents |
| CA2698508C (en) * | 2007-09-07 | 2017-06-06 | Alan R. Rapacki | Lacrimal implants and related methods |
| US9308124B2 (en) | 2007-12-20 | 2016-04-12 | University Of Southern California | Apparatus and methods for delivering therapeutic agents |
| US20090192493A1 (en) | 2008-01-03 | 2009-07-30 | University Of Southern California | Implantable drug-delivery devices, and apparatus and methods for refilling the devices |
| JP5552482B2 (ja) | 2008-04-30 | 2014-07-16 | キュー エル ティー インク． | 複合涙管挿入物および関連する方法 |
| EP2898911A1 (en) | 2008-05-08 | 2015-07-29 | MiniPumps, LLC | Implantable pumps and cannulas therefor |
| CN102202708B (zh) | 2008-05-08 | 2015-01-21 | 迷你泵有限责任公司 | 药物输送泵及其制造方法 |
| US9849238B2 (en) | 2008-05-08 | 2017-12-26 | Minipumps, Llc | Drug-delivery pump with intelligent control |
| CN102202706A (zh) * | 2008-05-08 | 2011-09-28 | 迷你泵有限责任公司 | 可植入药物传送装置与用于填充该装置的设备和方法 |
| BRPI0912182A2 (pt) * | 2008-05-09 | 2015-10-06 | Qlt Plug Delivery Inc | distribuição de liberação prolongada de agentes ativos pára tratar glaucoma e hipertensão ocular |
| TW201012469A (en) * | 2008-06-24 | 2010-04-01 | Qlt Plug Delivery Inc | Combination treatment of glaucoma |
| US20100104654A1 (en) * | 2008-10-27 | 2010-04-29 | Allergan, Inc. | Prostaglandin and prostamide drug delivery systems and intraocular therapeutic uses thereof |
| WO2010071844A1 (en) * | 2008-12-19 | 2010-06-24 | Qlt Plug Delivery, Inc | Substance delivering punctum implants and methods |
| SG173069A1 (en) * | 2009-01-23 | 2011-08-29 | Quadra Logic Tech Inc | Sustained released delivery of one or more agents |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| CA3045436C (en) | 2009-01-29 | 2025-10-07 | Forsight Vision4 Inc | Posterior segment drug delivery |
| KR20110132369A (ko) * | 2009-02-23 | 2011-12-07 | 큐엘티 인코포레이티드 | 눈물 임플란트 및 관련 방법 |
| US20100226962A1 (en) * | 2009-03-03 | 2010-09-09 | Rodstrom Theron R | Peri-corneal drug delivery device |
| US9421127B2 (en) | 2009-03-31 | 2016-08-23 | Johnson & Johnson Vision Care, Inc. | Punctal plugs |
| TWI495459B (zh) * | 2009-03-31 | 2015-08-11 | Johnson & Johnson Vision Care | 淚管塞（二） |
| JP5937004B2 (ja) | 2009-05-18 | 2016-06-22 | ドーズ メディカル コーポレーションＤｏｓｅ Ｍｅｄｉｃａｌ Ｃｏｒｐｏｒａｔｉｏｎ | 薬剤溶出眼内インプラント |
| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| WO2012071476A2 (en) | 2010-11-24 | 2012-05-31 | David Haffner | Drug eluting ocular implant |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| JP5695035B2 (ja) | 2009-06-03 | 2015-04-01 | フォーサイト・ビジョン５・インコーポレイテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ５，Ｉｎｃ． | 前眼部薬物供給 |
| US8709467B2 (en) | 2009-06-26 | 2014-04-29 | Cute Lovable Teddy Bear, Llc. | Para-xylylene based microfilm elution devices |
| CN102576385B (zh) | 2009-08-18 | 2016-02-24 | 迷你泵有限责任公司 | 具有自适应控制的电解药物输送泵 |
| US8469934B2 (en) * | 2010-01-27 | 2013-06-25 | Alcon Research, Ltd. | Pulsatile peri-corneal drug delivery device |
| US10166142B2 (en) | 2010-01-29 | 2019-01-01 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
| US9259352B2 (en) * | 2010-03-29 | 2016-02-16 | Johnson & Johnson Vision Care, Inc. | Punctal plugs |
| US9259351B2 (en) * | 2010-03-29 | 2016-02-16 | Johnson & Johnson Vision Care, Inc. | Punctal plugs |
| RU2012146630A (ru) * | 2010-04-06 | 2014-05-20 | Аллерган, Инк. | Имплантаты в виде резервуаров с замедленным высвобождением для внутрикамерной доставки лекарственных средств |
| HUE054113T2 (hu) | 2010-08-05 | 2021-08-30 | Forsight Vision4 Inc | Injekciós készülék gyógyszerbejuttatáshoz |
| HUE057267T2 (hu) * | 2010-08-05 | 2022-05-28 | Forsight Vision4 Inc | Berendezés szem kezelésére |
| CN103153316B (zh) | 2010-08-05 | 2015-08-19 | 弗赛特影像4股份有限公司 | 组合药物递送方法和设备 |
| US8591484B2 (en) | 2010-09-15 | 2013-11-26 | AlphaMed, Inc. | Lacrimal punctum measurement and occlusion |
| EP2640360A2 (en) | 2010-11-19 | 2013-09-25 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
| US9603997B2 (en) | 2011-03-14 | 2017-03-28 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
| US9919099B2 (en) | 2011-03-14 | 2018-03-20 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
| US10286146B2 (en) | 2011-03-14 | 2019-05-14 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
| WO2012149278A1 (en) | 2011-04-29 | 2012-11-01 | Allergan, Inc. | Sustained release latanoprost implant |
| US10398592B2 (en) | 2011-06-28 | 2019-09-03 | Forsight Vision4, Inc. | Diagnostic methods and apparatus |
| US20130018360A1 (en) * | 2011-07-13 | 2013-01-17 | Marissa Dockendorf | Method for delivering ophthalmic drugs |
| DK3290024T3 (da) | 2011-08-29 | 2019-06-03 | Mati Therapeutics Inc | Vedvarende indgivelse af aktive midler til behandling af glaukom og okulær hypertension |
| US9974685B2 (en) | 2011-08-29 | 2018-05-22 | Mati Therapeutics | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
| ES2912370T3 (es) | 2011-09-14 | 2022-05-25 | Forsight Vision5 Inc | Aparato para inserción ocular |
| SI2755600T1 (sl) | 2011-09-16 | 2021-08-31 | Forsight Vision4, Inc. | Naprava za izmenjavo tekočine |
| US8911227B2 (en) * | 2012-01-11 | 2014-12-16 | Johnson & Johnson Vision Care, Inc. | Device for injection molding silicone rubber |
| US10010448B2 (en) | 2012-02-03 | 2018-07-03 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| FR2986703B1 (fr) * | 2012-02-09 | 2015-01-16 | Horus Pharma | Dispositif de conditionnement et de distribution d'un produit a usage ophtalmique |
| WO2013164671A1 (en) | 2012-05-03 | 2013-11-07 | Qlt Inc. | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
| RU2520834C2 (ru) * | 2012-09-11 | 2014-06-27 | Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Дагестанский Государственный Технический Университет" (Дгту) | Способ профилактики и лечения синдрома сухих глаз |
| CN104884006B (zh) | 2012-10-26 | 2017-12-15 | 弗赛特影像5股份有限公司 | 用于持续释放药物到眼睛的眼科系统 |
| CN105142710A (zh) | 2013-01-15 | 2015-12-09 | 科罗拉多州立大学董事会,公司实体 | 泪腺系统给药装置 |
| AU2014236455B2 (en) | 2013-03-14 | 2018-07-12 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
| EP2978406A1 (en) * | 2013-03-27 | 2016-02-03 | Forsight Vision5, Inc. | Bimatoprost ocular silicone inserts and methods of use thereof |
| ES2972168T3 (es) | 2013-03-28 | 2024-06-11 | Forsight Vision4 Inc | Implante oftálmico para administración de sustancias terapéuticas |
| CA2927321A1 (en) * | 2013-10-15 | 2015-04-23 | Forsight Vision5, Inc. | Formulations and methods for increasing or reducing mucus |
| EP3148491B1 (en) | 2014-05-29 | 2020-07-01 | Glaukos Corporation | Implants with controlled drug delivery features and manufacturing method for said implants |
| RU2557423C1 (ru) * | 2014-06-25 | 2015-07-20 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт глазных болезней" (ФГБНУ "НИИ глазных болезней") | Способ лечения частичного дакриостеноза |
| WO2016011191A1 (en) | 2014-07-15 | 2016-01-21 | Forsight Vision4, Inc. | Ocular implant delivery device and method |
| CA2957548A1 (en) | 2014-08-08 | 2016-02-11 | Forsight Vision4, Inc. | Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof |
| BR112017009660A2 (pt) | 2014-11-10 | 2017-12-19 | Forsight Vision4 Inc | dispositivos de administração de fármacos expansíveis e métodos de utilização |
| KR102511830B1 (ko) | 2014-11-25 | 2023-03-17 | 엑시모어 엘티디. | 단일 및 다수 생체활성제를 전달하기 위한 조성물 및 방법 |
| WO2016168141A1 (en) | 2015-04-13 | 2016-10-20 | Forsight Vision5, Inc. | Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent |
| CN106264777A (zh) * | 2015-06-08 | 2017-01-04 | 三鼎生物科技股份有限公司 | 辅助排泪管 |
| US11925578B2 (en) | 2015-09-02 | 2024-03-12 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
| WO2017053751A1 (en) * | 2015-09-24 | 2017-03-30 | California Institute Of Technology | Implantable device for retaining live cells and providing nutrients thereto |
| US11564833B2 (en) | 2015-09-25 | 2023-01-31 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
| JP6912475B2 (ja) | 2015-11-20 | 2021-08-04 | フォーサイト・ビジョン フォー・インコーポレーテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ４， Ｉｎｃ． | 持続放出性薬物送達機器用の多孔質構造体 |
| EP3380040B1 (en) | 2015-11-23 | 2023-04-19 | The Regents of The University of Colorado, A Body Corporate | Lacrimal system for drug delivery |
| AR108177A1 (es) | 2016-04-05 | 2018-07-25 | Forsight Vision4 Inc | Dispositivos de suministro de fármacos oculares implantables |
| JP7003110B2 (ja) | 2016-04-20 | 2022-01-20 | ドーズ メディカル コーポレーション | 生体吸収性眼球薬物送達デバイス |
| US11207211B2 (en) | 2016-05-20 | 2021-12-28 | The Regents Of The University Of Colorado, A Body Corporate | Lacrimal drug delivery device |
| CN106667656A (zh) * | 2016-06-30 | 2017-05-17 | 广州聚明生物科技有限公司 | 生物可降解泪道栓及其制备方法和应用 |
| JP7278969B2 (ja) * | 2017-05-30 | 2023-05-22 | エキシモア・リミテッド | ドライアイ症候群を治療するための抗生物質マクロライドを送達する組成物および方法 |
| CN115607358A (zh) | 2017-11-21 | 2023-01-17 | 弗赛特影像4股份有限公司 | 用于可扩展端口递送系统的流体交换装置及使用方法 |
| EP3893721A4 (en) * | 2019-01-18 | 2022-10-12 | Avisi Technologies, Inc. | Method and device for treating eye disease |
| KR102414314B1 (ko) * | 2019-02-27 | 2022-06-30 | 사회복지법인 삼성생명공익재단 | 코팅층을 포함하는 안질환용 임플란트 |
| CN111643269B (zh) * | 2020-05-14 | 2024-09-13 | 海思盖德(苏州)生物医学科技有限公司 | 一种植入体的多次植入装置及植入方法 |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
Family Cites Families (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3949750A (en) | 1974-10-07 | 1976-04-13 | Freeman Jerre M | Punctum plug and method for treating keratoconjunctivitis sicca (dry eye) and other ophthalmic aliments using same |
| US3992518A (en) | 1974-10-24 | 1976-11-16 | G. D. Searle & Co. | Method for making a microsealed delivery device |
| US4053580A (en) | 1975-01-01 | 1977-10-11 | G. D. Searle & Co. | Microsealed pharmaceutical delivery device |
| FR2534580A1 (fr) | 1982-10-13 | 1984-04-20 | Synthelabo | Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent |
| US4660546A (en) | 1984-11-07 | 1987-04-28 | Robert S. Herrick | Method for treating for deficiency of tears |
| US5049142A (en) | 1984-11-07 | 1991-09-17 | Herrick Robert S | Intracanalicular implant for horizontal canalicular blockade treatment of the eye |
| US5053030A (en) | 1984-11-07 | 1991-10-01 | Herrick Robert S | Intracanalicular implant for horizontal canalicular blockade treatment of the eye |
| US5151444B1 (en) | 1987-09-18 | 1999-07-06 | R Tech Ueno Ltd | Ocular hypotensive agents |
| US4923699A (en) | 1988-06-03 | 1990-05-08 | Kaufman Herbert E | Eye treatment suspension |
| US4915684A (en) | 1988-06-21 | 1990-04-10 | Mackeen Donald L | Method and apparatus for modulating the flow of lacrimal fluid through a punctum and associated canaliculus |
| ATE420857T1 (de) | 1988-09-06 | 2009-01-15 | Pfizer Health Ab | Prostaglandin-derivate zur behandlung von glaukom und ocularer hypertension |
| US5296504A (en) | 1988-09-06 | 1994-03-22 | Kabi Pharmacia | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| SU1671295A1 (ru) * | 1988-10-24 | 1991-08-23 | Туркменский государственный медицинский институт | Устройство дл регулировани внутриглазного давлени при глаукоме |
| US4959048A (en) | 1989-01-17 | 1990-09-25 | Helix Medical, Inc. | Lacrimal duct occluder |
| US5067491A (en) * | 1989-12-08 | 1991-11-26 | Becton, Dickinson And Company | Barrier coating on blood contacting devices |
| US5171270A (en) | 1990-03-29 | 1992-12-15 | Herrick Robert S | Canalicular implant having a collapsible flared section and method |
| US5163959A (en) | 1990-03-29 | 1992-11-17 | Herrick Robert S | Method for treating an eye with a canalicular implant having a collapsible flared section |
| US5378475A (en) | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
| US5283063A (en) | 1992-01-31 | 1994-02-01 | Eagle Vision | Punctum plug method and apparatus |
| ES2166353T3 (es) | 1992-03-19 | 2002-04-16 | R Tech Ueno Ltd | Tratamiento de la hipertension ocular con beta-bloqueantes y derivados del acido prostanoico. |
| US5469867A (en) | 1992-09-02 | 1995-11-28 | Landec Corporation | Cast-in place thermoplastic channel occluder |
| US5352708A (en) | 1992-09-21 | 1994-10-04 | Allergan, Inc. | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US5922773A (en) | 1992-12-04 | 1999-07-13 | The Children's Medical Center Corp. | Glaucoma treatment |
| US5417651A (en) | 1993-07-01 | 1995-05-23 | Guena; Nicolas | Punctum plug and monocanalicular probe for lacrimal pathology |
| US5510383A (en) | 1993-08-03 | 1996-04-23 | Alcon Laboratories, Inc. | Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension |
| WO1995005161A1 (en) | 1993-08-13 | 1995-02-23 | Vitaphore Corporation | Hydrogel-based microsphere drug delivery systems |
| US5423777A (en) | 1993-10-27 | 1995-06-13 | Tajiri; Akira | Punctum plug |
| JP3486758B2 (ja) | 1994-06-24 | 2004-01-13 | 株式会社高研 | 注入可能な涙小管閉鎖剤 |
| US6149684A (en) | 1995-06-07 | 2000-11-21 | Herrick; Robert S. | Punctum plug having a thin elongated lip and a distal starting tip and method of using |
| US5723005A (en) | 1995-06-07 | 1998-03-03 | Herrick Family Limited Partnership | Punctum plug having a collapsible flared section and method |
| US5773019A (en) | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
| US5741292A (en) | 1995-10-26 | 1998-04-21 | Eagle Vision | Punctum dilating and plug inserting instrument with push-button plug release |
| JP3792775B2 (ja) | 1996-04-08 | 2006-07-05 | 有限会社エム・エル・シー | 涙道挿管器具 |
| JPH1033584A (ja) | 1996-07-26 | 1998-02-10 | M L C:Kk | 涙道挿管器具 |
| US6016806A (en) | 1997-03-27 | 2000-01-25 | Eaglevision, Inc | Punctum plug |
| US6041785A (en) | 1997-03-27 | 2000-03-28 | Eaglevision, Inc. | Punctum plug |
| US6027470A (en) | 1998-06-10 | 2000-02-22 | Eagle Vision, Inc. | Punctum plug and method for inserting the same into the punctual opening |
| US5830171A (en) | 1997-08-12 | 1998-11-03 | Odyssey Medical, Inc. | Punctal occluder |
| NL1008090C2 (nl) | 1998-01-22 | 1999-07-26 | Lubberman Bernardus H M | Plug voor het afsluiten van een traanbuis. |
| US6290684B1 (en) | 1998-03-02 | 2001-09-18 | Herrick Family Limited Partnership | Punctum plug having a collapsible expanded section and distal tip extending substantially perpendicular thereto and method of inserting same |
| US6196993B1 (en) | 1998-04-20 | 2001-03-06 | Eyelab Group, Llc | Ophthalmic insert and method for sustained release of medication to the eye |
| US6306114B1 (en) | 1998-06-16 | 2001-10-23 | Eagle Vision, Inc. | Valved canalicular plug for lacrimal duct occlusion |
| ES2243232T3 (es) | 1999-02-23 | 2005-12-01 | Angiotech International Ag | Composiciones y metodos para mejorar la integridad de cavidades y vias corporales comprometidas. |
| US6234175B1 (en) | 1999-03-23 | 2001-05-22 | Medennium, Inc. | Smart ocular plug design and method of insertion for punctal and intracanalicular implants |
| US6383192B1 (en) | 1999-04-28 | 2002-05-07 | Mlc Limited Company | Apparatus for intubation of lacrimal duct |
| US6344047B1 (en) | 2000-02-02 | 2002-02-05 | Eagle Vision | Instrument for inserting a punctum plug and method for manufacturing the instrument |
| AU2001234337A1 (en) | 2000-08-04 | 2002-02-18 | Medennium, Inc. | Ocular plug for punctal and intracanalicular implants |
| EP1372602B1 (en) | 2001-01-09 | 2007-04-18 | Microchips, Inc. | Flexible microchip devices for ophthalmic and other applications |
| US6827738B2 (en) * | 2001-01-30 | 2004-12-07 | Timothy R. Willis | Refractive intraocular implant lens and method |
| US6685626B2 (en) | 2001-02-02 | 2004-02-03 | Regeneration Technologies, Inc. | Compositions, devices, methods, and kits for induction of adhesions |
| JP2002263124A (ja) | 2001-03-12 | 2002-09-17 | Masashige Nakayama | 動物の眼病治療方法及びそれに用いる人工涙管 |
| US6605108B2 (en) * | 2001-04-13 | 2003-08-12 | Eagle Vision, Inc. | Monocanalicular stent |
| US20040022853A1 (en) | 2001-04-26 | 2004-02-05 | Control Delivery Systems, Inc. | Polymer-based, sustained release drug delivery system |
| US7404825B2 (en) | 2001-06-11 | 2008-07-29 | Herrick Ii Robert S | Implant capable of forming a differential image in an eye |
| DE10133870A1 (de) | 2001-07-12 | 2003-02-06 | Chris P Lohmann | Ophthalmisches Mittel, Verwendung von EGF zur Behandlung von Dry Eye-Syndrom und Insert zur Verabreichung von EGF am Auge |
| US7204995B2 (en) | 2002-01-31 | 2007-04-17 | El-Sherif Dalia M | Treatment and control of dry eye by use of biodegradable polymer capsules |
| US20040043067A1 (en) * | 2002-06-19 | 2004-03-04 | Salamone Joseph C. | Fluorosiloxane matrix controlled diffusion drug delivery systems |
| WO2004006890A1 (en) | 2002-07-15 | 2004-01-22 | Alcon, Inc. | Non-polymeric lipophilic pharmaceutical implant compositions for intraocular use |
| FR2844182B1 (fr) | 2002-09-11 | 2004-12-03 | Humanoptics Ag | Bouchon d'obturation d'un canalicule lacrymal |
| DE60325240D1 (de) | 2002-09-26 | 2009-01-22 | Angiotech Int Ag | Perivaskuläre hüllen |
| AU2004207523A1 (en) | 2003-01-24 | 2004-08-12 | Control Delivery Systems, Inc. | Controlled release of highly soluble agents |
| AR043356A1 (es) | 2003-01-24 | 2005-07-27 | Control Delivery Sys Inc | Dispositvo de liberacion sostenida para la administracion ocular de inhibidores de la anhidrasa carbonica y uso de inhibidores de la anhidrasa carbonica para su preparacion |
| AU2004237774B2 (en) | 2003-05-02 | 2009-09-10 | Surmodics, Inc. | Implantable controlled release bioactive agent delivery device |
| WO2005049105A2 (en) * | 2003-11-10 | 2005-06-02 | Angiotech International Ag | Medical implants and anti-scarring agents |
| US20050232972A1 (en) | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
| US7799336B2 (en) * | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
| US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
| WO2005121735A2 (en) * | 2004-06-07 | 2005-12-22 | California Institute Of Technology | Implantable mechanical pressure sensor and method of manufacturing the same |
| CN101052435B (zh) | 2004-07-02 | 2010-12-08 | Qlt塞子传递公司 | 治疗介质递送装置 |
| US7117870B2 (en) | 2004-07-26 | 2006-10-10 | Clarity Corporation | Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same |
| US7575781B2 (en) * | 2004-08-03 | 2009-08-18 | Sur Modics, Inc. | Method for depositing a polymeric coating on a substrate |
| US20080038317A1 (en) | 2004-09-10 | 2008-02-14 | Chin-Ming Chang | Therapeutic Lacrimal Canalicular Inserts And Related Methods |
| ES2640458T3 (es) | 2006-03-31 | 2017-11-03 | Mati Therapeutics Inc. | Implantes del sistema de drenaje nasolagrimal para terapia medicamentosa |
| US20080045911A1 (en) | 2006-06-21 | 2008-02-21 | Borgia Maureen J | Punctal plugs for the delivery of active agents |
| US9173773B2 (en) | 2006-06-21 | 2015-11-03 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
| US9474645B2 (en) | 2006-06-21 | 2016-10-25 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
| US20080086101A1 (en) | 2006-08-25 | 2008-04-10 | David Freilich | Ophthalmic insert |
-
2008
- 2008-01-28 UY UY30883A patent/UY30883A1/es not_active Application Discontinuation
- 2008-01-29 AR ARP080100354A patent/AR065235A1/es not_active Application Discontinuation
- 2008-01-30 PT PT08728546T patent/PT2114531E/pt unknown
- 2008-01-30 JP JP2009548415A patent/JP2010517630A/ja active Pending
- 2008-01-30 RU RU2009132493/15A patent/RU2459646C2/ru not_active IP Right Cessation
- 2008-01-30 BR BRPI0807340A patent/BRPI0807340A2/pt not_active IP Right Cessation
- 2008-01-30 CA CA002674913A patent/CA2674913A1/en not_active Abandoned
- 2008-01-30 HR HRP20120608AT patent/HRP20120608T1/hr unknown
- 2008-01-30 US US12/022,520 patent/US8753666B2/en active Active
- 2008-01-30 ES ES08728546T patent/ES2390991T3/es active Active
- 2008-01-30 EP EP08728546A patent/EP2114531B1/en not_active Not-in-force
- 2008-01-30 PL PL08728546T patent/PL2114531T3/pl unknown
- 2008-01-30 DK DK08728546.6T patent/DK2114531T3/da active
- 2008-01-30 ZA ZA200904713A patent/ZA200904713B/xx unknown
- 2008-01-30 KR KR1020097016725A patent/KR20090104099A/ko not_active Ceased
- 2008-01-30 SI SI200830714T patent/SI2114531T1/sl unknown
- 2008-01-30 WO PCT/US2008/052439 patent/WO2008094989A2/en not_active Ceased
- 2008-01-30 MX MX2009007394A patent/MX2009007394A/es active IP Right Grant
- 2008-01-30 AU AU2008210541A patent/AU2008210541B2/en not_active Ceased
- 2008-01-30 TW TW097103499A patent/TW200838485A/zh unknown
- 2008-01-30 CN CN200880003681XA patent/CN101600476B/zh not_active Expired - Fee Related
- 2008-01-31 CL CL200800306A patent/CL2008000306A1/es unknown
-
2012
- 2012-08-24 CY CY20121100764T patent/CY1113075T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20120608T1 (hr) | 2012-08-31 |
| AU2008210541A1 (en) | 2008-08-07 |
| RU2459646C2 (ru) | 2012-08-27 |
| EP2114531A2 (en) | 2009-11-11 |
| CA2674913A1 (en) | 2008-08-07 |
| US20080181930A1 (en) | 2008-07-31 |
| PT2114531E (pt) | 2012-10-09 |
| RU2009132493A (ru) | 2011-03-10 |
| MX2009007394A (es) | 2009-08-12 |
| SI2114531T1 (sl) | 2012-09-28 |
| CN101600476B (zh) | 2013-08-21 |
| CY1113075T1 (el) | 2016-04-13 |
| CN101600476A (zh) | 2009-12-09 |
| KR20090104099A (ko) | 2009-10-05 |
| JP2010517630A (ja) | 2010-05-27 |
| AR065235A1 (es) | 2009-05-27 |
| PL2114531T3 (pl) | 2012-10-31 |
| WO2008094989A2 (en) | 2008-08-07 |
| EP2114531B1 (en) | 2012-07-11 |
| TW200838485A (en) | 2008-10-01 |
| US8753666B2 (en) | 2014-06-17 |
| ES2390991T3 (es) | 2012-11-20 |
| UY30883A1 (es) | 2008-05-31 |
| ZA200904713B (en) | 2010-09-29 |
| CL2008000306A1 (es) | 2008-09-05 |
| AU2008210541B2 (en) | 2013-09-26 |
| HK1133218A1 (en) | 2010-03-19 |
| WO2008094989A3 (en) | 2009-04-30 |
| BRPI0807340A2 (pt) | 2017-05-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK2114531T3 (da) | Punktpropper og fremgangsmåder til indgivelse af terapeutiske midler | |
| DK2185164T3 (da) | Sammensætning og terapeutisk antitumorvaccine | |
| DK2222675T3 (da) | 5-anilinoimidazopyridiner og fremgangsmåder til deres anvendelse | |
| IL250734A0 (en) | Transdermal therapeutic system | |
| DK3424932T3 (da) | Bronophthalider til terapeutisk anvendelse | |
| DK2320911T3 (da) | Vasokonstriktionspræparater og fremgangsmåder til anvendelse deraf | |
| DK3092901T3 (da) | Quinolonanaloger og fremgangsmåder relateret dertil | |
| BRPI0812562A2 (pt) | composições terapêuticas anti-cd20 e métodos | |
| DK2147315T3 (da) | Diabetesrelaterede biomarkører og fremgangsmåder til anvendelse deraf | |
| EP2035005A4 (en) | THERAPY BASED ON CYTOKINE INHIBITORS | |
| BRPI0916931A2 (pt) | agentes terapêuticos | |
| DK2337568T3 (da) | Fremgangsmåder og midler til blødvævsteknologi | |
| EP2212350A4 (en) | THERAPEUTIC AND DIAGNOSTIC PROCEDURES USING TIM-3 | |
| DK2058020T3 (da) | Indretning til indgivelse af lægemiddel | |
| DK2209375T3 (da) | Parp-inhibitorforbindelser, præparater og fremgangsmåder til anvendelse deraf | |
| DK2144905T3 (da) | Terapeutiske midler | |
| ES2398124T8 (es) | Procedimiento y dispositivos para la modificación de sesión de terceros | |
| DK2035369T3 (da) | Terapeutiske | |
| DK2356093T3 (da) | Carbazolforbindelser og terapeutiske anvendelser af forbindelserne | |
| DK2229360T3 (da) | Indolinonderivater og fremgangsmåde til deres fremstilling | |
| CR10571A (es) | Vacuna virica recombinante | |
| DK2340042T3 (da) | Fremgangsmåder og præparater til behandling af cancer | |
| DK2170827T3 (da) | Indolin-2-oner og aza-indolin-2-oner | |
| HUE036071T2 (hu) | Macitentánt tartalmazó terápiás készítmények | |
| EP2373658A4 (en) | STAT3 INHIBITORS AND THERAPEUTIC PROCEDURES WHERE THEREOF ARE USED |