[go: up one dir, main page]

EP2035005A4 - Therapy using cytokine inhibitors - Google Patents

Therapy using cytokine inhibitors

Info

Publication number
EP2035005A4
EP2035005A4 EP07798190A EP07798190A EP2035005A4 EP 2035005 A4 EP2035005 A4 EP 2035005A4 EP 07798190 A EP07798190 A EP 07798190A EP 07798190 A EP07798190 A EP 07798190A EP 2035005 A4 EP2035005 A4 EP 2035005A4
Authority
EP
European Patent Office
Prior art keywords
therapy
cytokine inhibitors
cytokine
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07798190A
Other languages
German (de)
French (fr)
Other versions
EP2035005A2 (en
Inventor
Constance A Crowley
Nancy G J Delaet
Justin Ernst
Carrie Gail Grove
Bonnie Hepburn
Bernard King
Christopher J Larson
Stephen Miller
Kent Pryor
Lewis J Shuster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kemia Inc
Original Assignee
Kemia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kemia Inc filed Critical Kemia Inc
Publication of EP2035005A2 publication Critical patent/EP2035005A2/en
Publication of EP2035005A4 publication Critical patent/EP2035005A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP07798190A 2006-06-09 2007-06-06 Therapy using cytokine inhibitors Withdrawn EP2035005A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US81226806P 2006-06-09 2006-06-09
US83307806P 2006-07-24 2006-07-24
US83527006P 2006-08-03 2006-08-03
PCT/US2007/070547 WO2007146712A2 (en) 2006-06-09 2007-06-06 Therapy using cytokine inhibitors

Publications (2)

Publication Number Publication Date
EP2035005A2 EP2035005A2 (en) 2009-03-18
EP2035005A4 true EP2035005A4 (en) 2011-07-06

Family

ID=38832677

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07798190A Withdrawn EP2035005A4 (en) 2006-06-09 2007-06-06 Therapy using cytokine inhibitors

Country Status (8)

Country Link
EP (1) EP2035005A4 (en)
AR (1) AR061273A1 (en)
AU (1) AU2007257959A1 (en)
CA (1) CA2691214A1 (en)
CL (1) CL2007001670A1 (en)
PE (1) PE20080935A1 (en)
TW (1) TW200814998A (en)
WO (1) WO2007146712A2 (en)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ570625A (en) 2006-02-10 2011-10-28 Biomarin Iga Ltd Treatment of duchenne muscular dystrophy
US7989459B2 (en) 2006-02-17 2011-08-02 Pharmacopeia, Llc Purinones and 1H-imidazopyridinones as PKC-theta inhibitors
TW200831104A (en) 2006-10-04 2008-08-01 Pharmacopeia Inc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
WO2008043019A1 (en) 2006-10-04 2008-04-10 Pharmacopeia, Inc 8-substituted 2-(benzimidazolyl) purine derivatives for immunosuppression
US7902187B2 (en) 2006-10-04 2011-03-08 Wyeth Llc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
US7902248B2 (en) 2006-12-14 2011-03-08 Hoffmann-La Roche Inc. Oxime glucokinase activators
US8440832B2 (en) * 2007-07-13 2013-05-14 Board Of Regents, The University Of Texas System Heterocyclic modulators of cannabinoid receptors
PL2170396T3 (en) 2007-08-03 2017-07-31 Summit (Oxford) Limited Drug combinations for the treatment of duchenne muscular dystrophy
JP5627574B2 (en) 2008-06-03 2014-11-19 インターミューン, インコーポレイテッド Compounds and methods for treating inflammatory and fibrotic diseases
EP2352730A4 (en) * 2008-11-07 2012-04-25 Lundbeck & Co As H BIOLOGICALLY ACTIVE AMIDES
JP2012529432A (en) 2009-06-05 2012-11-22 リンク・メディスン・コーポレーション Aminopyrrolidinone derivatives and uses thereof
WO2011063076A1 (en) * 2009-11-19 2011-05-26 Itherx Pharmaceuticals, Inc. Methods of treating hepatitis c virus with oxoacetamide compounds
US8663661B2 (en) * 2009-12-23 2014-03-04 Ratiopharm Gmbh Solid pharmaceutical dosage form of ticagrelor
US8802868B2 (en) 2010-03-25 2014-08-12 Vertex Pharmaceuticals Incorporated Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
RU2639876C2 (en) 2010-03-30 2017-12-25 Версеон Корпорейшн Multi-substituted aromatic compounds as thrombin inhibitors
CA2797118C (en) 2010-04-22 2021-03-30 Vertex Pharmaceuticals Incorporated Process of producing cycloalkylcarboxamido-indole compounds
AR081331A1 (en) 2010-04-23 2012-08-08 Cytokinetics Inc AMINO- PYRIMIDINES COMPOSITIONS OF THE SAME AND METHODS FOR THE USE OF THE SAME
EP2560488B1 (en) 2010-04-23 2015-10-28 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
AR081626A1 (en) 2010-04-23 2012-10-10 Cytokinetics Inc AMINO-PYRIDAZINIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND USE OF THE SAME TO TREAT CARDIAC AND SKELETIC MUSCULAR DISORDERS
US8759380B2 (en) 2011-04-22 2014-06-24 Cytokinetics, Inc. Certain heterocycles, compositions thereof, and methods for their use
CH707030B1 (en) 2011-10-21 2015-03-13 Abbvie Inc Combination treatment of DAAs for use in the treatment of HCV
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
ES2529143B1 (en) 2011-10-21 2015-10-26 Abbvie Inc. COMBINATION OF AT LEAST TWO DIRECT ACTION ANTIVIRAL AGENTS, RIBAVIRINE BUT NOT INTERFERONED FOR THE USE OF HCV TREATMENT
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
AR092742A1 (en) 2012-10-02 2015-04-29 Intermune Inc ANTIFIBROTIC PYRIDINONES
MX373964B (en) 2013-03-15 2020-07-13 Verseon Corp MULTI-SUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS.
MX382781B (en) 2014-04-02 2025-03-13 Intermune Inc ANTI-FIBROTIC PYRIDINONES.
CA2944140C (en) 2014-04-15 2022-10-04 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases
US10189810B2 (en) 2014-09-17 2019-01-29 Verseon Corporation Pyrazolyl-substituted pyridone compounds as serine protease inhibitors
EP3230279A1 (en) 2014-12-10 2017-10-18 Massachusetts Institute of Technology Fused 1,3-azole derivatives useful for the treatment of proliferative diseases
SI3261639T1 (en) 2015-02-27 2023-01-31 Verseon International Corporation Substituted pyrazole compounds as serine protease inhibitors
ES2858750T3 (en) * 2015-06-12 2021-09-30 Univ Greenwich Triazine derivatives as gamma interferon inhibitors
MA52119A (en) 2015-10-19 2018-08-29 Ncyte Corp HETEROCYCLIC COMPOUNDS USED AS IMMUNOMODULATORS
MY199220A (en) 2015-11-19 2023-10-20 Incyte Corp Heterocyclic compounds as immunomodulators
TWI728017B (en) 2015-12-15 2021-05-21 瑞典商阿斯特捷利康公司 Isoindole compounds, pharmaceutical composition comprising the same, and uses thereof
JP6911031B2 (en) 2015-12-22 2021-07-28 インサイト・コーポレイションIncyte Corporation Heterocyclic compounds as immunomodulators
CA3012846A1 (en) 2016-02-16 2017-08-24 Massachusetts Institute Of Technology Max binders as myc modulators and uses thereof
EP3448392A4 (en) 2016-04-28 2020-01-15 Emory University ALCYNE-CONTAINING NUCLEOTIDES AND NUCLEOSIDES THERAPEUTIC COMPOSITIONS AND USES THEREOF
TW201808950A (en) 2016-05-06 2018-03-16 英塞特公司 Heterocyclic compounds as immunomodulators
US20170342060A1 (en) 2016-05-26 2017-11-30 Incyte Corporation Heterocyclic compounds as immunomodulators
JP7349790B2 (en) * 2016-06-08 2023-09-25 サポート-ヴェンチャー ゲゼルシャフト ミット ベシュレンクター ハフトゥング Pharmaceutical combinations to treat cancer
MY197280A (en) 2016-06-20 2023-06-09 Incyte Corp Heterocyclic compounds as immunomodulators
EP3484866B1 (en) 2016-07-14 2022-09-07 Incyte Corporation Heterocyclic compounds as immunomodulators
MA46045A (en) 2016-08-29 2021-04-28 Incyte Corp HETEROCYCLIC COMPOUNDS USED AS IMMUNOMODULATORS
KR102220971B1 (en) 2016-12-20 2021-02-25 아스트라제네카 아베 Amino-triazolopyridine compounds and their use in cancer treatment
BR112019012993A2 (en) 2016-12-22 2019-12-03 Incyte Corporation benzo-oxazole derivatives as immunomodulators
MA47099A (en) 2016-12-22 2021-05-12 Incyte Corp BICYCLIC HETEROAROMATIC COMPOUNDS USED AS IMMUNOMODULATORS
PT3558990T (en) 2016-12-22 2022-11-21 Incyte Corp Tetrahydro imidazo[4,5-c]pyridine derivatives as pd-l1 internalization inducers
US20180179201A1 (en) 2016-12-22 2018-06-28 Incyte Corporation Heterocyclic compounds as immunomodulators
ES2899402T3 (en) 2016-12-22 2022-03-11 Incyte Corp Pyridine derivatives as immunomodulators
KR20200018440A (en) * 2017-05-15 2020-02-19 리커리엄 아이피 홀딩스, 엘엘씨 Painkiller compounds
CN110730780A (en) 2017-06-14 2020-01-24 阿斯利康(瑞典)有限公司 2,3-Dihydroisoindole-1-carboxamide as a ROR-gamma modulator
CN107474043A (en) * 2017-09-13 2017-12-15 厦门稀土材料研究所 Nicotinic acid derivatives and their preparation methods and uses
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
PT3691620T (en) 2017-10-05 2022-10-06 Fulcrum Therapeutics Inc P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd
MX2020006587A (en) 2017-12-22 2020-12-10 Ravenna Pharmaceuticals Inc Aminopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors.
HRP20230090T1 (en) 2018-03-30 2023-03-17 Incyte Corporation HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS
HUE061503T2 (en) 2018-05-11 2023-07-28 Incyte Corp Tetrahydroimidazo[4,5-C]pyridine derivatives as PD-L1 immunomodulators
HRP20230243T1 (en) 2018-06-07 2023-04-14 Idorsia Pharmaceuticals Ltd Alkoxy-substituted pyridinyl derivatives as lpa1 receptor antagonists and their use in the treatment of fibrosis
US20220079911A1 (en) * 2018-09-13 2022-03-17 Eirion Therapeutics, Inc. Uses of plasminogen activator inhibitor 1 (pai-1) inhibitors
WO2020113088A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Diarylhydantoin compounds and methods of use thereof
CA3121202A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
CN111825605B (en) * 2019-04-19 2023-03-31 中国科学院上海药物研究所 Aryl ketone amide compound and preparation method and application thereof
TW202112767A (en) 2019-06-17 2021-04-01 美商佩特拉製藥公司 Aminopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors
AR119162A1 (en) 2019-06-18 2021-12-01 Idorsia Pharmaceuticals Ltd PYRIDIN-3-YL DERIVATIVES
US11753406B2 (en) 2019-08-09 2023-09-12 Incyte Corporation Salts of a PD-1/PD-L1 inhibitor
PH12022550754A1 (en) 2019-09-30 2023-08-23 Incyte Corp Pyrido[3,2-d]pyrimidine compounds as immunomodulators
WO2021092240A1 (en) * 2019-11-05 2021-05-14 Dermira, Inc. Mrgprx2 antagonists for the treatment of inflammatory disorders
AU2020385113A1 (en) 2019-11-11 2022-05-19 Incyte Corporation Salts and crystalline forms of a PD-1/PD-L1 inhibitor
LT4069691T (en) 2019-12-06 2024-12-10 Vertex Pharmaceuticals Incorporated SUBSTITUTED TETRAHYDROFURANS AS SODIUM CHANNEL MODULATORS
MX2023005362A (en) 2020-11-06 2023-06-22 Incyte Corp Process for making a pd-1/pd-l1 inhibitor and salts and crystalline forms thereof.
TW202233615A (en) 2020-11-06 2022-09-01 美商英塞特公司 Crystalline form of a pd-1/pd-l1 inhibitor
WO2022099018A1 (en) 2020-11-06 2022-05-12 Incyte Corporation Process of preparing a pd-1/pd-l1 inhibitor
CN113209112B (en) * 2021-02-06 2021-12-24 广州市朝利良生物科技有限公司 Novel coronavirus resistant medicine based on ACE2 and S protein binding target and application thereof
DK4347031T3 (en) 2021-06-04 2025-12-01 Vertex Pharma N-(HYDROXYALKYL-(HETERO)ARYL)-TETRAHYDROFURAN-CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS
EP4479138A1 (en) 2022-02-14 2024-12-25 Accent Therapeutics, Inc. Inhibitors of rna helicase dhx9 and uses thereof
WO2024059220A2 (en) * 2022-09-15 2024-03-21 Vanderbilt University 6,5 southwestern core compounds as mglu5 negative allosteric modulators and methods of making and using the same
CN118496159B (en) * 2024-07-18 2024-09-24 广州医科大学附属市八医院 Application of compound in preparation of medicine with liver fibrosis preventing and/or treating effect

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030008868A1 (en) * 2001-05-16 2003-01-09 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as anti-inflammatory agents
WO2005023761A2 (en) * 2003-09-11 2005-03-17 Kemia, Inc. Cytokine inhibitors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030008868A1 (en) * 2001-05-16 2003-01-09 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as anti-inflammatory agents
WO2005023761A2 (en) * 2003-09-11 2005-03-17 Kemia, Inc. Cytokine inhibitors
US20100273797A1 (en) * 2003-09-11 2010-10-28 Itherx Pharmaceuticals, Inc. Alpha-ketoamides and derivatives thereof

Also Published As

Publication number Publication date
TW200814998A (en) 2008-04-01
AU2007257959A1 (en) 2007-12-21
WO2007146712A3 (en) 2008-11-27
AR061273A1 (en) 2008-08-13
PE20080935A1 (en) 2008-08-02
EP2035005A2 (en) 2009-03-18
WO2007146712A2 (en) 2007-12-21
CA2691214A1 (en) 2007-12-21
CL2007001670A1 (en) 2008-01-18

Similar Documents

Publication Publication Date Title
EP2035005A4 (en) Therapy using cytokine inhibitors
EP2214669A4 (en) Cytokine inhibitors
EP2026843A4 (en) Therapeutic uses of inhibitors of rtp801l
GB2436010B (en) Therapy device
IL196559A0 (en) Combination therapy
GB0609492D0 (en) Therapeutic agents
SI2338487T1 (en) Combination therapy with PARP inhibitors
IL179398A0 (en) Dpp-ib inhibitors
GB0608928D0 (en) Therapeutic agents
IL193674A0 (en) Therapeutic piperazines as pde4 inhibitors
IL197818A0 (en) Multiple sclerosis therapy
GB0601962D0 (en) Therapeutic agents
IL196556A0 (en) Combination therapy
SI2094702T1 (en) Viral inhibitors
EP2054061A4 (en) Combination therapy
GB0616214D0 (en) Therapeutic Agents
ZA200902203B (en) Combination therapy
EP2131858A4 (en) P38 inhibitors
IL198026A0 (en) Sequential combination therapy
GB0611152D0 (en) Therapeutic agents
GB0421355D0 (en) Inhibitors
GB0620818D0 (en) Therapeutic agents
EP1816194A4 (en) Cancer-cell-specific proliferation inhibitors
GB0620059D0 (en) Therapeutic agents
GB0609676D0 (en) Therapeutic agents

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20090108

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK RS

RIN1 Information on inventor provided before grant (corrected)

Inventor name: SHUSTER, LEWIS, J.

Inventor name: PRYOR, KENT

Inventor name: MILLER, STEPHEN

Inventor name: LARSON, CHRISTOPHER, J.

Inventor name: KING, BERNARD

Inventor name: HEPBURN, BONNIE

Inventor name: GROVE, CARRIE, GAIL

Inventor name: ERNST, JUSTIN

Inventor name: DELAET, NANCY G., J.

Inventor name: CROWLEY, CONSTANCE, A.

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20110607

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20120105