DK1828167T3 - Acrylamidderivater som antibiotiske midler - Google Patents
Acrylamidderivater som antibiotiske midlerInfo
- Publication number
- DK1828167T3 DK1828167T3 DK05858503.5T DK05858503T DK1828167T3 DK 1828167 T3 DK1828167 T3 DK 1828167T3 DK 05858503 T DK05858503 T DK 05858503T DK 1828167 T3 DK1828167 T3 DK 1828167T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibiotic agents
- acrylamide derivatives
- acrylamide
- derivatives
- antibiotic
- Prior art date
Links
- 150000003926 acrylamides Chemical class 0.000 title 1
- 230000003115 biocidal effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57694504P | 2004-06-04 | 2004-06-04 | |
| PCT/US2005/019805 WO2007053131A2 (en) | 2004-06-04 | 2005-06-06 | Acrylamide derivatives as antibiotic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1828167T3 true DK1828167T3 (da) | 2014-10-20 |
Family
ID=37889654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05858503.5T DK1828167T3 (da) | 2004-06-04 | 2005-06-06 | Acrylamidderivater som antibiotiske midler |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8450307B2 (da) |
| EP (2) | EP1828167B1 (da) |
| JP (1) | JP5087406B2 (da) |
| KR (1) | KR101299399B1 (da) |
| CA (1) | CA2568914C (da) |
| CY (1) | CY1115713T1 (da) |
| DK (1) | DK1828167T3 (da) |
| ES (1) | ES2515101T3 (da) |
| PL (1) | PL1828167T3 (da) |
| PT (1) | PT1828167E (da) |
| SI (1) | SI1828167T1 (da) |
| WO (1) | WO2007053131A2 (da) |
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| HK1049656A1 (zh) | 1999-10-08 | 2003-05-23 | Smithkline Beecham Corporation | Fab i抑制剂 |
| DK1560584T3 (da) * | 2001-04-06 | 2009-05-18 | Affinium Pharm Inc | Fab I inhibitorer |
| CA2658506C (en) | 2006-07-20 | 2016-01-26 | Affinium Pharmaceuticals, Inc. | Acrylamide derivatives as fab 1 inhibitors |
| EP2125802A4 (en) | 2007-02-16 | 2014-08-20 | Debiopharm Int Sa | SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS |
| CN101965186A (zh) * | 2007-11-28 | 2011-02-02 | 塞阔伊亚药品公司 | 抑制细胞色素p450 2d6的化合物和方法 |
| WO2010089993A1 (ja) | 2009-02-03 | 2010-08-12 | クミアイ化学工業株式会社 | 縮合環化した２－ピリドン誘導体及び除草剤 |
| BR112012011793A2 (pt) | 2009-11-18 | 2019-09-24 | Fab Pharma Sas | "acrilamidas heterocíclicas e seu uso como farmacêuticos" |
| WO2011131748A2 (en) | 2010-04-21 | 2011-10-27 | Probiodrug Ag | Novel inhibitors |
| HUP1000598A2 (en) | 2010-11-05 | 2012-09-28 | Richter Gedeon Nyrt | Indole derivatives |
| ES2974690T3 (es) | 2010-11-05 | 2024-07-01 | Firmenich Incorporated | Compuestos útiles como moduladores de la TRPM8 |
| MX360856B (es) * | 2011-08-10 | 2018-11-20 | Janssen Sciences Ireland Uc | 3,4-dihidro-1h-[1,8]naftiridinosas sustituidas con homopiperidinilo antibacterianas. |
| CN105503869A (zh) | 2011-08-10 | 2016-04-20 | 爱尔兰詹森科学公司 | 抗细菌的哌啶基取代的3,4-二氢-1h-[1,8]萘啶酮 |
| JO3611B1 (ar) | 2011-08-10 | 2020-08-27 | Janssen Sciences Ireland Uc | سايكلو بنتا (سي (بيرول 4,3 ثاني هيدرو 1 hمستبدله [8,1] نافثيريدينونات مضادة للجراثيم |
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| EA201590339A1 (ru) * | 2012-08-10 | 2015-06-30 | Янссен Сайенсиз Айрлэнд Юси | Новые антибактериальные соединения |
| AU2013301452B2 (en) * | 2012-08-10 | 2017-06-01 | Janssen Sciences Ireland Uc | New antibacterial compounds |
| WO2014072930A2 (en) * | 2012-11-09 | 2014-05-15 | Aurigene Discovery Technologies Limited | Fused pyridine derivatives as antibacterial agents |
| MX389514B (es) | 2015-10-01 | 2025-03-20 | Firmenich Incorporated | Compuestos útiles como moduladores de canal receptor 8 de potencial transitorio de melastatina (trpm8). |
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| SMT202400519T1 (it) * | 2018-11-12 | 2025-01-14 | Debiopharm Int Sa | Composti antibiotici. metodi di produzione degli stessi, composizioni farmaceutiche contenenti gli stessi e loro usi |
| CA3129508A1 (en) | 2019-02-14 | 2020-08-20 | Debiopharm International S.A. | Solid formulations of afabicin with histidine |
| UA129222C2 (uk) | 2019-06-14 | 2025-02-12 | Дебіофарм Інтернешнл С.А. | Лікарський засіб і його застосування для лікування бактеріальних інфекцій, пов'язаних з біоплівкою |
| US10947253B2 (en) | 2019-08-05 | 2021-03-16 | Ankh Life Sciences Limited | Fused polycyclic dimers |
| US20230140808A1 (en) * | 2020-04-07 | 2023-05-04 | Sanofi | (1 H-Indol-5-YL)Acrylamide Derivatives as Inhibitors of Tead Proteins and the Hippo-YAP1/TAZ Signaling Cascade for the Treatment of Cancer |
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| CN111991385A (zh) * | 2020-08-17 | 2020-11-27 | 暨南大学 | 棕榈油酸在抑制水产病原菌中的应用 |
| WO2022187329A1 (en) * | 2021-03-03 | 2022-09-09 | The Board Of Trustees Of The University Of Illinois | Fabi inhibitors for gram-negative pathogens |
| US12060148B2 (en) | 2022-08-16 | 2024-08-13 | Honeywell International Inc. | Ground resonance detection and warning system and method |
| WO2025073269A1 (zh) * | 2023-10-07 | 2025-04-10 | 广州白云山医药集团股份有限公司白云山制药总厂 | 一种FabI酶抑制剂及其应用 |
| WO2025078209A1 (en) * | 2023-10-09 | 2025-04-17 | Debiopharm International S.A. | Antibiotic compounds for treating bacterial infections |
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-
2005
- 2005-06-06 SI SI200531900T patent/SI1828167T1/sl unknown
- 2005-06-06 ES ES05858503.5T patent/ES2515101T3/es not_active Expired - Lifetime
- 2005-06-06 PL PL05858503T patent/PL1828167T3/pl unknown
- 2005-06-06 US US11/628,569 patent/US8450307B2/en not_active Expired - Fee Related
- 2005-06-06 CA CA2568914A patent/CA2568914C/en not_active Expired - Fee Related
- 2005-06-06 WO PCT/US2005/019805 patent/WO2007053131A2/en not_active Ceased
- 2005-06-06 PT PT58585035T patent/PT1828167E/pt unknown
- 2005-06-06 EP EP05858503.5A patent/EP1828167B1/en not_active Expired - Lifetime
- 2005-06-06 JP JP2007543017A patent/JP5087406B2/ja not_active Expired - Fee Related
- 2005-06-06 EP EP14179596.3A patent/EP2848614A3/en not_active Withdrawn
- 2005-06-06 KR KR1020077000169A patent/KR101299399B1/ko not_active Expired - Fee Related
- 2005-06-06 DK DK05858503.5T patent/DK1828167T3/da active
-
2013
- 2013-04-25 US US13/870,193 patent/US20140107106A1/en not_active Abandoned
-
2014
- 2014-10-31 CY CY20141100905T patent/CY1115713T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1828167T1 (sl) | 2014-12-31 |
| PL1828167T3 (pl) | 2015-02-27 |
| ES2515101T3 (es) | 2014-10-29 |
| EP1828167A2 (en) | 2007-09-05 |
| JP5087406B2 (ja) | 2012-12-05 |
| WO2007053131A3 (en) | 2007-08-02 |
| EP2848614A2 (en) | 2015-03-18 |
| CA2568914A1 (en) | 2005-12-04 |
| JP2008505194A (ja) | 2008-02-21 |
| US8450307B2 (en) | 2013-05-28 |
| CY1115713T1 (el) | 2017-01-25 |
| WO2007053131A2 (en) | 2007-05-10 |
| US20140107106A1 (en) | 2014-04-17 |
| KR20080016517A (ko) | 2008-02-21 |
| KR101299399B1 (ko) | 2013-08-22 |
| EP1828167B1 (en) | 2014-08-06 |
| PT1828167E (pt) | 2014-10-08 |
| EP2848614A3 (en) | 2015-07-29 |
| CA2568914C (en) | 2013-09-24 |
| US20100093705A1 (en) | 2010-04-15 |
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