DK169816B1 - Amidforbindelser, farmaceutisk præparat indeholdende samme samt fremgangsmåde til fremstilling af forbindelserne - Google Patents
Amidforbindelser, farmaceutisk præparat indeholdende samme samt fremgangsmåde til fremstilling af forbindelserne Download PDFInfo
- Publication number
- DK169816B1 DK169816B1 DK492288A DK492288A DK169816B1 DK 169816 B1 DK169816 B1 DK 169816B1 DK 492288 A DK492288 A DK 492288A DK 492288 A DK492288 A DK 492288A DK 169816 B1 DK169816 B1 DK 169816B1
- Authority
- DK
- Denmark
- Prior art keywords
- lower alkyl
- ethoxy
- compound
- amino
- benzyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Cephalosporin Compounds (AREA)
- Hybrid Electric Vehicles (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Catalysts (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22121187 | 1987-09-05 | ||
| JP62221211A JPS6466153A (en) | 1987-09-05 | 1987-09-05 | Amide compound and digestive tract motion-activator containing said compound as active ingredient |
| JP23625087 | 1987-09-22 | ||
| JP62236250A JPS6479144A (en) | 1987-09-22 | 1987-09-22 | Amide compound and agent for promoting motion of digestive tract containing said compound |
| JP62242765A JPS6485960A (en) | 1987-09-29 | 1987-09-29 | Amide compound and reactivator for motion of digestive tube comprising said compound as active ingredient |
| JP24276587 | 1987-09-29 | ||
| JP24974987 | 1987-10-05 | ||
| JP62249749A JPH0193568A (ja) | 1987-10-05 | 1987-10-05 | アミド化合物、及びそれを有効成分とする消化管運動賦活剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK492288D0 DK492288D0 (da) | 1988-09-05 |
| DK492288A DK492288A (da) | 1989-03-06 |
| DK169816B1 true DK169816B1 (da) | 1995-03-06 |
Family
ID=27476995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK492288A DK169816B1 (da) | 1987-09-05 | 1988-09-05 | Amidforbindelser, farmaceutisk præparat indeholdende samme samt fremgangsmåde til fremstilling af forbindelserne |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4983633A (uk) |
| EP (1) | EP0306827B1 (uk) |
| KR (1) | KR940000058B1 (uk) |
| AT (1) | ATE66913T1 (uk) |
| AU (1) | AU606988B2 (uk) |
| BG (1) | BG48932A3 (uk) |
| CA (1) | CA1335101C (uk) |
| DE (1) | DE3864636D1 (uk) |
| DK (1) | DK169816B1 (uk) |
| ES (1) | ES2037779T3 (uk) |
| FI (1) | FI87644C (uk) |
| HU (1) | HU198447B (uk) |
| SU (1) | SU1627082A3 (uk) |
| UA (1) | UA6330A1 (uk) |
| YU (1) | YU46706B (uk) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5864039A (en) * | 1994-03-30 | 1999-01-26 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzoic acid compounds and use thereof as medicaments |
| WO1995026953A1 (en) * | 1994-03-30 | 1995-10-12 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzoic acid compound and use thereof as medicine |
| KR0147963B1 (ko) * | 1995-01-10 | 1998-08-17 | 강박광 | 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법 |
| WO2000028984A1 (fr) * | 1998-11-16 | 2000-05-25 | Hokuriku Seiyaku Co., Ltd. | Remedes agissant contre un trouble fonctionnel du tractus digestif |
| AU6834000A (en) | 1999-08-07 | 2001-03-05 | Boehringer Ingelheim Pharma Kg | Carboxylic acid amides, their production and their use as drugs |
| DE10235312A1 (de) | 2002-08-01 | 2004-02-12 | Basf Ag | Verfahren zur Herstellung von Aminoalkoxybenzylaminen und Aminoalkoxybenzonitrilen als Zwischenprodukte |
| CN1305837C (zh) * | 2004-06-11 | 2007-03-21 | 吉林修正药业新药研发中心 | 一种改进的伊托必利原料药的制备方法 |
| KR100595117B1 (ko) * | 2004-07-28 | 2006-06-30 | 일양약품주식회사 | 이토프라이드·염산염 중간체인4-[2-(디메틸아미노)에톡시]벤질아민의 새로운 제조방법 |
| ITMI20042168A1 (it) * | 2004-11-12 | 2005-02-12 | Erregierre Spa | Processo di preparazione di itopride cloridrato |
| KR100663167B1 (ko) * | 2005-10-27 | 2007-01-02 | 동우신테크 주식회사 | 염산 이토프리드의 제조방법 |
| WO2007074386A2 (en) * | 2005-12-28 | 2007-07-05 | Bakulesh Mafatlal Khamar | A novel process for synthesis of itopride and it’s novel intermediate-n-(4-hydroxybenzyl)-3,4-dimethoxybenzamide |
| KR100836528B1 (ko) * | 2007-07-25 | 2008-06-10 | 주식회사 휴온스 | 이토프리드 염산염의 제조방법 |
| CN101967103A (zh) * | 2010-09-28 | 2011-02-09 | 浙江金伯士药业有限公司 | 一种伊托必利中间体的制备新方法 |
| CN103073446B (zh) * | 2011-10-26 | 2014-12-24 | 珠海保税区丽珠合成制药有限公司 | 盐酸伊托必利的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1069640B (de) * | 1959-11-26 | F. Hoffmann-La Roche S. Co. Aktiengesellschaft, Basel (Schweiz) | Verfahren zur Herstellung von anfemetisch wirksamen Benzylaminderivaten | |
| FR1525M (fr) * | 1961-07-25 | 1962-11-16 | Ile De France | Médicaments antiémétiques nouveaux. |
| NL130752C (uk) * | 1964-05-07 |
-
1988
- 1988-08-19 YU YU160088A patent/YU46706B/sh unknown
- 1988-08-30 CA CA000576117A patent/CA1335101C/en not_active Expired - Lifetime
- 1988-09-01 DE DE8888114257T patent/DE3864636D1/de not_active Expired - Lifetime
- 1988-09-01 AT AT88114257T patent/ATE66913T1/de not_active IP Right Cessation
- 1988-09-01 EP EP88114257A patent/EP0306827B1/en not_active Expired - Lifetime
- 1988-09-01 ES ES198888114257T patent/ES2037779T3/es not_active Expired - Lifetime
- 1988-09-02 KR KR1019880011317A patent/KR940000058B1/ko not_active Expired - Lifetime
- 1988-09-02 SU SU4356531A patent/SU1627082A3/ru active
- 1988-09-02 BG BG085365A patent/BG48932A3/xx unknown
- 1988-09-02 US US07/241,028 patent/US4983633A/en not_active Expired - Lifetime
- 1988-09-02 UA UA4356531A patent/UA6330A1/uk unknown
- 1988-09-02 HU HU884538A patent/HU198447B/hu unknown
- 1988-09-05 DK DK492288A patent/DK169816B1/da not_active IP Right Cessation
- 1988-09-05 FI FI884077A patent/FI87644C/fi not_active IP Right Cessation
- 1988-09-05 AU AU21862/88A patent/AU606988B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3864636D1 (de) | 1991-10-10 |
| YU160088A (en) | 1990-06-30 |
| FI884077A7 (fi) | 1989-03-06 |
| FI87644B (fi) | 1992-10-30 |
| AU2186288A (en) | 1989-03-09 |
| SU1627082A3 (ru) | 1991-02-07 |
| ES2037779T3 (es) | 1993-07-01 |
| BG48932A3 (bg) | 1991-06-14 |
| UA6330A1 (uk) | 1994-12-29 |
| EP0306827A1 (en) | 1989-03-15 |
| AU606988B2 (en) | 1991-02-21 |
| DK492288A (da) | 1989-03-06 |
| HUT47531A (en) | 1989-03-28 |
| HU198447B (en) | 1989-10-30 |
| CA1335101C (en) | 1995-04-04 |
| YU46706B (sh) | 1994-04-05 |
| KR890005036A (ko) | 1989-05-11 |
| KR940000058B1 (ko) | 1994-01-05 |
| EP0306827B1 (en) | 1991-09-04 |
| US4983633A (en) | 1991-01-08 |
| ATE66913T1 (de) | 1991-09-15 |
| DK492288D0 (da) | 1988-09-05 |
| FI884077A0 (fi) | 1988-09-05 |
| FI87644C (fi) | 1993-02-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |