[go: up one dir, main page]

DK1688146T3 - Fremstilling af aldesleukin til farmaceutisk anvendelse - Google Patents

Fremstilling af aldesleukin til farmaceutisk anvendelse

Info

Publication number
DK1688146T3
DK1688146T3 DK05250680T DK05250680T DK1688146T3 DK 1688146 T3 DK1688146 T3 DK 1688146T3 DK 05250680 T DK05250680 T DK 05250680T DK 05250680 T DK05250680 T DK 05250680T DK 1688146 T3 DK1688146 T3 DK 1688146T3
Authority
DK
Denmark
Prior art keywords
aldesleukin
sds
pharmaceutical use
preparation
give
Prior art date
Application number
DK05250680T
Other languages
English (en)
Inventor
Maninder Hora
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of DK1688146T3 publication Critical patent/DK1688146T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2013IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/217IFN-gamma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK05250680T 2005-02-07 2005-02-07 Fremstilling af aldesleukin til farmaceutisk anvendelse DK1688146T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05250680A EP1688146B1 (en) 2005-02-07 2005-02-07 Preparing aldesleukin for pharmaceutical use

Publications (1)

Publication Number Publication Date
DK1688146T3 true DK1688146T3 (da) 2007-11-05

Family

ID=34940439

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05250680T DK1688146T3 (da) 2005-02-07 2005-02-07 Fremstilling af aldesleukin til farmaceutisk anvendelse

Country Status (10)

Country Link
EP (1) EP1688146B1 (da)
AT (1) ATE367167T1 (da)
CY (1) CY1108521T1 (da)
DE (1) DE602005001688T2 (da)
DK (1) DK1688146T3 (da)
ES (1) ES2289663T3 (da)
HR (1) HRP20070487T3 (da)
PL (1) PL1688146T3 (da)
PT (1) PT1688146E (da)
SI (1) SI1688146T1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010134091A1 (en) * 2009-05-20 2010-11-25 M/S. Provimi Animal Nutrition India Private Limited A process for preparation of a non-antibiotic growth promoter formula / product and its use in food animals
CA2816722C (en) 2010-11-12 2022-03-15 Nektar Therapeutics Conjugates of an il-2 moiety and a polymer
DK2925297T3 (da) * 2012-11-02 2017-10-02 Cytuvax Sammensætning omfattende cytokinmakroaggregater
HUE051414T2 (hu) 2014-08-11 2021-03-01 Delinia Inc Módosított IL-2 változatok, amelyek szelektíven aktiválnak regulátor T sejteket, autoimmun betegségek kezelésére
WO2017062832A1 (en) 2015-10-08 2017-04-13 Nektar Therapeutics Combination of an il-2rbeta-selective agonist and a long-acting il-15 agonist
CA3001429C (en) 2015-10-22 2023-07-11 Iltoo Pharma Pharmaceutical compositions of il-2
US20170204154A1 (en) 2016-01-20 2017-07-20 Delinia, Inc. Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
EP3538548A4 (en) 2016-11-08 2020-08-19 Delinia, Inc. IL-2 VARIANTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
PE20200303A1 (es) 2017-05-24 2020-02-06 Novartis Ag Proteinas de anticuerpo injertadas con citocina y metodos de uso en el tratamiento del cancer
JP7646540B2 (ja) * 2018-06-13 2025-03-17 アクロン バイオプロダクツ,エルエルシー. 液体医薬組成物中で非常に安定な治療的に活性なアルデスロイキンを調製する方法
US11690963B2 (en) 2018-08-22 2023-07-04 Qnovia, Inc. Electronic device for producing an aerosol for inhalation by a person
TWI888357B (zh) 2018-08-22 2025-07-01 美商奎諾維亞公司 用於產生供人體吸入的氣霧的電子裝置
US11517685B2 (en) 2019-01-18 2022-12-06 Qnovia, Inc. Electronic device for producing an aerosol for inhalation by a person
US12471625B2 (en) 2020-11-01 2025-11-18 Qnovia, Inc. Electronic devices and liquids for aerosolizing and inhaling therewith
CN116549609A (zh) 2022-01-27 2023-08-08 北京良远生物医药研究有限公司 一种il2制剂、其制备方法及应用
EP4510873A1 (en) 2022-04-22 2025-02-26 Qnovia, Inc. Electronic devices for aerosolizing and inhaling liquid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604377A (en) * 1984-03-28 1986-08-05 Cetus Corporation Pharmaceutical compositions of microbially produced interleukin-2

Also Published As

Publication number Publication date
EP1688146B1 (en) 2007-07-18
EP1688146A1 (en) 2006-08-09
DE602005001688T2 (de) 2008-04-10
SI1688146T1 (sl) 2007-12-31
PT1688146E (pt) 2007-10-29
CY1108521T1 (el) 2014-04-09
ATE367167T1 (de) 2007-08-15
DE602005001688D1 (de) 2007-08-30
PL1688146T3 (pl) 2007-12-31
HRP20070487T3 (en) 2007-12-31
ES2289663T3 (es) 2008-02-01

Similar Documents

Publication Publication Date Title
CY1108521T1 (el) Παρασκευη αλδεσλευκινης για φαρμακευτικη χρηση
CY1114298T1 (el) Διαμορφωτικως περιορισμενα διφαινυλ παραγωγα για χρηση ως αναστολεις ιου ηπατιτιδας c
CO6210752A2 (es) Compuestos biciclicos y uso como antidiabeticos
ES2422556T3 (es) Tratamiento de hepatitis vírica
DE602007007666D1 (de) Verfahren zur herstellung von nebivolol
EA200702347A1 (ru) Способ получения глюкопиранозилзамещённых производных бензилбензола и промежуточных продуктов для их получения
CY1112653T1 (el) Κρυσταλλικες τροποποιησεις της πυρακλοστροβινης
ATE542803T1 (de) Verfahren zur herstellung von dihydrochinazolinen
WO2010021717A3 (en) Hcv protease inhibitors
TW200700092A (en) Tigecycline compositions and methods of preparation
EA201101085A1 (ru) Феноксиуксусные кислоты в качестве активаторов ppar дельта
BRPI0606112A2 (pt) 3 - heteroaril - 3 - hidróxi - 2 - amino - propil aminas e compostos relacionados, bem como uso dos mesmos e composição farmacêutica
EA200701707A1 (ru) Пиразолопиримидины
WO2009007535A3 (fr) Derives de 7 -alkynyl-1.8-naphthyrid0nes, leur preparation et leur application en therapeutique
CR8559A (es) Pirazolopirimidinas
MX2007003031A (es) Compuestos heteroarilo para uso como betamimeticos en el tratamiento de enfermedades de vias respiratorias.
TW200730518A (en) Crystalline forms of docetaxel and processes for their preparation
MX2009006615A (es) Proceso para la preparacion y usos de novedosos compuestos de bis(dialquilamida).
EA200900780A1 (ru) Аналоги эпотилона, модифицированные в положениях c12-c13, как противораковые лекарственные средства
ATE413875T1 (de) Zusammensetzungen enthaltend levetiracetam und verfahren zu deren herstellung.
WO2007115929A8 (de) Thiazolyl-dihydro-quinazoline
NO20074528L (no) Substituerte pyrroler, sammensetninger, fremgangsmate for fremstilling og anvendelse av samme
HK1086757A1 (en) Preparing aldesleukin for pharmaceutical use
EA200701201A1 (ru) Новая фармацевтическая композиция для вакцин
ATE477791T1 (de) Otologische lösung und verfahren zu ihrer herstellung