DK1527179T3 - IL-7-lægemiddelsubstans, IL-7-holdig sammensætning, fremstilling og anvendelser deraf - Google Patents
IL-7-lægemiddelsubstans, IL-7-holdig sammensætning, fremstilling og anvendelser derafInfo
- Publication number
- DK1527179T3 DK1527179T3 DK03792262.2T DK03792262T DK1527179T3 DK 1527179 T3 DK1527179 T3 DK 1527179T3 DK 03792262 T DK03792262 T DK 03792262T DK 1527179 T3 DK1527179 T3 DK 1527179T3
- Authority
- DK
- Denmark
- Prior art keywords
- drug substance
- drug
- product
- preparation
- well
- Prior art date
Links
- 108010002586 Interleukin-7 Proteins 0.000 title abstract 6
- 229940088679 drug related substance Drugs 0.000 title abstract 4
- 239000008186 active pharmaceutical agent Substances 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 102000000704 Interleukin-7 Human genes 0.000 abstract 4
- 239000012535 impurity Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 229940126534 drug product Drugs 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 230000008105 immune reaction Effects 0.000 abstract 1
- 229940100994 interleukin-7 Drugs 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5418—IL-7
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- AIDS & HIV (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02291996A EP1391513A1 (en) | 2002-08-08 | 2002-08-08 | IL-7 drug substance, IL-7 comprising composition, preparation and uses thereof |
| US47588103P | 2003-06-05 | 2003-06-05 | |
| PCT/EP2003/008701 WO2004018681A2 (en) | 2002-08-08 | 2003-08-06 | Il-7 drug substance, il- 7 comprising composition, preparation and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1527179T3 true DK1527179T3 (da) | 2011-01-03 |
Family
ID=30775891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03792262.2T DK1527179T3 (da) | 2002-08-08 | 2003-08-06 | IL-7-lægemiddelsubstans, IL-7-holdig sammensætning, fremstilling og anvendelser deraf |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7585947B2 (da) |
| EP (2) | EP1391513A1 (da) |
| JP (3) | JP2005534339A (da) |
| AT (1) | ATE482273T1 (da) |
| AU (1) | AU2003250216B2 (da) |
| CA (1) | CA2494974C (da) |
| CY (1) | CY1110994T1 (da) |
| DE (1) | DE60334301D1 (da) |
| DK (1) | DK1527179T3 (da) |
| ES (1) | ES2353006T3 (da) |
| IL (1) | IL166543A (da) |
| NO (1) | NO332305B1 (da) |
| PL (1) | PL213710B1 (da) |
| PT (1) | PT1527179E (da) |
| SI (1) | SI1527179T1 (da) |
| WO (1) | WO2004018681A2 (da) |
| ZA (1) | ZA200501914B (da) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2367891T3 (es) | 2000-09-29 | 2011-11-10 | Schering Corporation | Interleucina-10 pegilada. |
| CA2487673C (en) * | 2003-12-02 | 2010-11-02 | F. Hoffmann-La Roche Ag | Improved method for the recombinant production and purification of protein kinases |
| BRPI0418286A (pt) | 2003-12-30 | 2007-05-02 | Merck Patent Gmbh | proteìnas de fusão de il-7 |
| EP1746161A1 (en) | 2005-07-20 | 2007-01-24 | Cytheris | Glycosylated IL-7, preparation and uses |
| CA2619989C (en) * | 2005-08-23 | 2014-06-17 | National Research Council Of Canada | Regulation of heterologous recombinant protein expression in methylotrophic and methanotrophic bacteria |
| EP2032695B1 (en) | 2006-05-31 | 2018-08-15 | The Regents of The University of California | Cd127 expression inversely correlates with foxp3 and suppressive function of cd4+ tregs |
| US20080081031A1 (en) | 2006-09-28 | 2008-04-03 | Schering Corporation | Use of Pegylated IL-10 to Treat Cancer |
| US9266937B2 (en) | 2010-12-10 | 2016-02-23 | University Of Central Florida Research Foundation, Inc. | Compositions comprising IL-7 receptor ligands |
| MX2014001355A (es) | 2011-08-03 | 2014-11-21 | Cytheris | Inmunoterapia contra el vhc. |
| JP6126684B2 (ja) * | 2012-04-23 | 2017-05-10 | バハラ バイオテック インターナショナル リミテッド | 新規なロタウイルスワクチン組成物及び同組成物を調製する方法 |
| RU2562169C2 (ru) * | 2012-10-29 | 2015-09-10 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства | Штамм культивируемых клеток cho-il7/13 - продуцент интерлейкина-7 человека |
| CA2908198A1 (en) | 2013-04-18 | 2014-10-23 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
| EP3434277A1 (en) | 2013-06-17 | 2019-01-30 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
| RU2016122957A (ru) | 2013-11-11 | 2017-12-19 | Армо Байосайенсиз, Инк. | Способы применения интерлейкина-10 для лечения заболеваний и расстройств |
| US20180028593A1 (en) | 2014-03-21 | 2018-02-01 | Boreal Invest | Terminal nanofiltration of solubilized protein compositions for removal of immunogenic aggregates |
| CN106573072A (zh) | 2014-06-02 | 2017-04-19 | 阿尔莫生物科技股份有限公司 | 降低血清胆固醇的方法 |
| CN107106655A (zh) | 2014-10-22 | 2017-08-29 | 阿尔莫生物科技股份有限公司 | 使用白细胞介素‑10治疗疾病和病症的方法 |
| WO2016126615A1 (en) | 2015-02-03 | 2016-08-11 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
| IL254389B2 (en) * | 2015-03-11 | 2023-03-01 | Nektar Therapeutics | Polymer conjugates and the il–7 group |
| KR20180020141A (ko) | 2015-05-28 | 2018-02-27 | 아르모 바이오사이언시스 인코포레이티드 | 암 치료에 사용되는 peg화된 인터류킨-10 |
| EP3307766A4 (en) * | 2015-06-11 | 2019-06-12 | Genexine, Inc. | MODIFIED INTERLEUKIN-7 PROTEIN AND USES THEREOF |
| KR102386735B1 (ko) * | 2015-11-06 | 2022-04-14 | 주식회사 제넥신 | 변형된 인터루킨-7 융합 단백질의 제형 |
| RU2615447C1 (ru) * | 2015-11-13 | 2017-04-04 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства | Синтетическая ДНК, кодирующая интерлейкин-7 человека, содержащий ее экспрессионный вектор (варианты), штамм-продуцент интерлейкина-7 человека и способ получения интерлейкина-7 человека |
| CN108697765A (zh) * | 2015-12-04 | 2018-10-23 | 格纳西尼有限公司 | 用于预防或治疗人乳头瘤病毒引起的疾病的含有免疫球蛋白fc融合il-7融合蛋白的药物组合物 |
| KR102604595B1 (ko) * | 2015-12-04 | 2023-11-21 | 주식회사 제넥신 | 면역글로불린 Fc가 융합된 인터루킨-7 융합 단백질을 포함하는 인플루엔자 바이러스 감염의 예방 또는 치료용 약학적 조성물 |
| WO2018156649A1 (en) * | 2017-02-22 | 2018-08-30 | Flagship Pioneering, Inc. | Compositions of t cell modulator (tcm) molecules and uses thereof |
| WO2020102728A1 (en) | 2018-11-16 | 2020-05-22 | Neoimmunetech, Inc. | Method of treating a tumor with a combination of il-7 protein and an immune checkpoint inhibitor |
| CA3123338A1 (en) | 2018-12-21 | 2020-06-25 | Ose Immunotherapeutics | Bifunctional anti-pd-1/il-7 molecule |
| KR102402276B1 (ko) * | 2019-11-15 | 2022-05-26 | 주식회사 제넥신 | 변형된 인터루킨-7 및 tgf 베타 수용체 ii를 포함하는 융합단백질 및 이의 용도 |
| JP2023512456A (ja) | 2020-01-13 | 2023-03-27 | ネオイミューンテック, インコーポレイテッド | Il-7タンパク質と二重特異性抗体の組み合わせで腫瘍を治療する方法 |
| JP2023512657A (ja) | 2020-02-05 | 2023-03-28 | ワシントン・ユニバーシティ | Il-7タンパク質とcar保有免疫細胞の組み合わせで固形腫瘍を治療する方法 |
| EP4232070A1 (en) | 2020-10-26 | 2023-08-30 | NeoImmuneTech, Inc. | Methods of inducing stem cell mobilization |
| EP4236989A1 (en) | 2020-11-02 | 2023-09-06 | NeoImmuneTech, Inc. | Use of interleukin-7 for the treatment of coronavirus |
| US20240115675A1 (en) | 2020-11-05 | 2024-04-11 | Neoimmunetech, Inc. | Method of treating a tumor with a combination of an il-7 protein and a nucleotide vaccine |
| US20240092851A1 (en) * | 2020-11-25 | 2024-03-21 | Jecho Laboratories, Inc. | Il-7 fusion protein and related methods |
| WO2022117569A1 (en) | 2020-12-02 | 2022-06-09 | Oncurious Nv | A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer |
| JP2025501238A (ja) | 2021-12-30 | 2025-01-17 | ネオイミューンテック, インコーポレイテッド | Il-7タンパク質とvegfアンタゴニストの併用による腫瘍の治療方法 |
| EP4463135A2 (en) | 2022-01-10 | 2024-11-20 | Sana Biotechnology, Inc. | Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses |
| WO2023193015A1 (en) | 2022-04-01 | 2023-10-05 | Sana Biotechnology, Inc. | Cytokine receptor agonist and viral vector combination therapies |
| WO2024102722A1 (en) | 2022-11-07 | 2024-05-16 | Neoimmunetech, Inc. | Methods of treating a tumor with an unmethylated mgmt promoter |
| CN117050178B (zh) * | 2023-10-13 | 2024-01-12 | 北京百普赛斯生物科技股份有限公司 | 特异性检测il-7的抗体及应用 |
| WO2025093541A1 (en) | 2023-10-31 | 2025-05-08 | Ose Immunotherapeutics | Combination of interleukin 7 and tumour associated antigen vaccine |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4965195A (en) * | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
| US5328988A (en) * | 1987-10-26 | 1994-07-12 | Immunex Corporation | Interleukin-7 |
| ZA887773B (en) * | 1987-10-26 | 1989-07-26 | Immunex Corp | Interleukin-7 |
| US5714585A (en) * | 1987-10-26 | 1998-02-03 | Sterling Winthrop, Inc. | Antibodies that are immunoreactive with interleukin-7 |
| US5728680A (en) * | 1987-12-30 | 1998-03-17 | Cytoven J.V. | Methods for normalizing numbers of lymphocytes |
| US5459058A (en) * | 1991-03-28 | 1995-10-17 | Benjamin Rich | Cell culture system |
| US5223408A (en) * | 1991-07-11 | 1993-06-29 | Genentech, Inc. | Method for making variant secreted proteins with altered properties |
| WO1994022473A1 (en) * | 1993-04-01 | 1994-10-13 | University Of Washington | Use of interleukin 7 to improve vaccine potency |
| US5696234A (en) * | 1994-08-01 | 1997-12-09 | Schering Corporation | Muteins of mammalian cytokine interleukin-13 |
| DE69838552T2 (de) * | 1997-07-14 | 2008-05-21 | Bolder Biotechnology, Inc., Louisville | Derivate des wachstumshormons und verwandte proteine |
| EP2314696A1 (en) * | 1998-09-21 | 2011-04-27 | Schering Corporation | Therapeutic uses of human Interleukin-B50 antagonist. |
| CA2404479A1 (en) * | 2000-03-30 | 2001-10-11 | University Of Connecticut | Hybrid cytokine of il-7 and .beta.-chain of hepatocyte growth factor |
| BRPI0418286A (pt) | 2003-12-30 | 2007-05-02 | Merck Patent Gmbh | proteìnas de fusão de il-7 |
| EP1746161A1 (en) | 2005-07-20 | 2007-01-24 | Cytheris | Glycosylated IL-7, preparation and uses |
-
2002
- 2002-08-08 EP EP02291996A patent/EP1391513A1/en not_active Withdrawn
-
2003
- 2003-08-06 US US10/522,883 patent/US7585947B2/en not_active Expired - Lifetime
- 2003-08-06 PT PT03792262T patent/PT1527179E/pt unknown
- 2003-08-06 DK DK03792262.2T patent/DK1527179T3/da active
- 2003-08-06 ES ES03792262T patent/ES2353006T3/es not_active Expired - Lifetime
- 2003-08-06 AU AU2003250216A patent/AU2003250216B2/en not_active Expired
- 2003-08-06 WO PCT/EP2003/008701 patent/WO2004018681A2/en not_active Ceased
- 2003-08-06 AT AT03792262T patent/ATE482273T1/de active
- 2003-08-06 PL PL373606A patent/PL213710B1/pl unknown
- 2003-08-06 SI SI200331907T patent/SI1527179T1/sl unknown
- 2003-08-06 JP JP2004530091A patent/JP2005534339A/ja active Pending
- 2003-08-06 DE DE60334301T patent/DE60334301D1/de not_active Expired - Lifetime
- 2003-08-06 CA CA2494974A patent/CA2494974C/en not_active Expired - Lifetime
- 2003-08-06 EP EP03792262A patent/EP1527179B1/en not_active Expired - Lifetime
-
2005
- 2005-01-25 NO NO20050355A patent/NO332305B1/no not_active IP Right Cessation
- 2005-01-27 IL IL166543A patent/IL166543A/en active IP Right Grant
- 2005-03-07 ZA ZA2005/01914A patent/ZA200501914B/en unknown
-
2009
- 2009-12-24 JP JP2009299560A patent/JP5980467B2/ja not_active Expired - Fee Related
-
2010
- 2010-12-17 CY CY20101101165T patent/CY1110994T1/el unknown
-
2014
- 2014-04-22 JP JP2014088394A patent/JP2014147396A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2494974C (en) | 2014-07-29 |
| CA2494974A1 (en) | 2004-03-04 |
| PL373606A1 (en) | 2005-09-05 |
| ZA200501914B (en) | 2005-11-30 |
| US7585947B2 (en) | 2009-09-08 |
| ATE482273T1 (de) | 2010-10-15 |
| JP5980467B2 (ja) | 2016-08-31 |
| IL166543A (en) | 2012-02-29 |
| EP1391513A1 (en) | 2004-02-25 |
| NO332305B1 (no) | 2012-08-20 |
| AU2003250216B2 (en) | 2010-08-05 |
| ES2353006T3 (es) | 2011-02-24 |
| JP2005534339A (ja) | 2005-11-17 |
| JP2014147396A (ja) | 2014-08-21 |
| HK1075465A1 (en) | 2005-12-16 |
| AU2003250216A1 (en) | 2004-03-11 |
| PL213710B1 (pl) | 2013-04-30 |
| WO2004018681A2 (en) | 2004-03-04 |
| US20050249701A1 (en) | 2005-11-10 |
| JP2010115203A (ja) | 2010-05-27 |
| PT1527179E (pt) | 2010-12-07 |
| IL166543A0 (en) | 2006-01-15 |
| WO2004018681A3 (en) | 2004-04-01 |
| SI1527179T1 (sl) | 2011-04-29 |
| EP1527179B1 (en) | 2010-09-22 |
| NO20050355L (no) | 2005-05-06 |
| DE60334301D1 (de) | 2010-11-04 |
| CY1110994T1 (el) | 2015-06-11 |
| EP1527179A2 (en) | 2005-05-04 |
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