DK1524981T3 - Sammensætninger med vedvarende frigivelse indeholdende lamotrigin - Google Patents

Sammensætninger med vedvarende frigivelse indeholdende lamotrigin

Info

Publication number: DK1524981T3
Authority: DK; Denmark
Prior art keywords: sustained; compositions containing; release compositions; containing lamotrigine; lamotrigine
Prior art date: 2002-07-29

Application number

DK03766343T

Other languages

English (en)

Inventor

Ian Richard Buxton

Robin Currie

Myrna A Dela-Cruz

Gary Wayne Goodson

Wlodzimierz Karolak

Mehran Maleki

Vijay Mohan Iyer

Gopal Muppirala

Alan Frank Parr

Jagdev Singh Sidhu

Robert Allen Stagner

Akunuri Venkata Vijay-Kumar

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-29

Filing date

2003-07-28

Publication date

2009-06-22

2002-07-29 Priority claimed from GB0217493A external-priority patent/GB0217493D0/en

2002-07-29 Priority claimed from GB0217492A external-priority patent/GB0217492D0/en

2003-06-13 Priority claimed from GB0313801A external-priority patent/GB0313801D0/en

2003-07-28 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2009-06-22 Application granted granted Critical

2009-06-22 Publication of DK1524981T3 publication Critical patent/DK1524981T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Immunology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK03766343T 2002-07-29 2003-07-28 Sammensætninger med vedvarende frigivelse indeholdende lamotrigin DK1524981T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB0217493A GB0217493D0 (en)	2002-07-29	2002-07-29	Novel methods of treatment
GB0217492A GB0217492D0 (en)	2002-07-29	2002-07-29	Novel method of treatment
GB0313801A GB0313801D0 (en)	2003-06-13	2003-06-13	Novel methods of treatment
PCT/EP2003/008368 WO2004012741A1 (en)	2002-07-29	2003-07-28	Sustained release formulations comprising lamotrigine

Publications (1)

Publication Number	Publication Date
DK1524981T3 true DK1524981T3 (da)	2009-06-22

Family

ID=31499035

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03766343T DK1524981T3 (da)	2002-07-29	2003-07-28	Sammensætninger med vedvarende frigivelse indeholdende lamotrigin

Country Status (28)

Country	Link
US (1)	US20050032799A1 (da)
EP (1)	EP1524981B1 (da)
JP (2)	JP4744142B2 (da)
KR (1)	KR100882707B1 (da)
CN (1)	CN100363007C (da)
AR (1)	AR040709A1 (da)
AT (1)	ATE424827T1 (da)
AU (1)	AU2003260336C1 (da)
BR (1)	BRPI0313148B8 (da)
CA (1)	CA2493301A1 (da)
CO (1)	CO5680405A2 (da)
CY (1)	CY1109119T1 (da)
DE (1)	DE60326590D1 (da)
DK (1)	DK1524981T3 (da)
ES (1)	ES2323268T3 (da)
IL (1)	IL166424A (da)
IS (1)	IS2681B (da)
MA (1)	MA27509A1 (da)
MX (1)	MXPA05001243A (da)
MY (1)	MY141049A (da)
NO (1)	NO334221B1 (da)
NZ (1)	NZ537885A (da)
PL (1)	PL213565B1 (da)
PT (1)	PT1524981E (da)
RU (1)	RU2325163C2 (da)
SI (1)	SI1524981T1 (da)
TW (1)	TWI342213B (da)
WO (1)	WO2004012741A1 (da)

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DK1524981T3 (da) *	2002-07-29	2009-06-22	Glaxo Group Ltd	Sammensætninger med vedvarende frigivelse indeholdende lamotrigin
EP1686967A4 (en) *	2003-11-25	2012-08-08	Smithkline Beecham Cork Ltd	CARVEDILOL-FREE BASE, SALTS, WATER-FREE FORMS OR SOLVATES THEREOF, CORRESPONDING PHARMACEUTICAL COMPOSITIONS, CONTROLLED RELEASE FORMULAS AND TREATMENT OR DISPOSAL PROCEDURES
US20060039975A1 (en) *	2004-08-20	2006-02-23	Zalman Vilkov	Paroxetine formulations
EP1874282B1 (en) *	2005-04-06	2010-09-15	Adamas Pharmaceuticals, Inc.	Methods and compositions for treatment of cns disorders
WO2008109343A1 (en) *	2007-03-01	2008-09-12	Memory Pharmaceuticals Corporation	Methods of treating bipolar disorder and memory and/or cognitive impairment associated therewith with (+)-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyano-phenyl)-1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylate
US20090022789A1 (en) *	2007-07-18	2009-01-22	Supernus Pharmaceuticals, Inc.	Enhanced formulations of lamotrigine
WO2009061513A1 (en) *	2007-11-09	2009-05-14	Thar Pharmaceuticals	Crystalline forms of lamotrigine
US20090196924A1 (en) *	2008-02-04	2009-08-06	Pramod Kharwade	Controlled-release lamotrigine formulations
US20100323016A1 (en) *	2008-07-18	2010-12-23	Biljana Nadjsombati	Modified release formulation and methods of use
MX2011000636A (es) *	2008-07-18	2011-08-03	Valeant Pharmaceuticals Int	Formulacion de liberacion modificada y metodos de uso.
US20100323015A1 (en) *	2008-07-18	2010-12-23	Biljana Nadjsombati	Modified release formulation and methods of use
JP5885668B2 (ja)	2009-12-02	2016-03-15	アダマスファーマシューティカルズ，インコーポレイテッド	アマンタジン組成物および使用方法
WO2011086568A1 (en) *	2010-01-13	2011-07-21	Accutest Research Laboratories (I) Pvt. Ltd	Controlled release composition for lamotrigine
KR20140016260A (ko) *	2011-02-03	2014-02-07	루핀 리미티드	베포타스틴의 경구용 방출 조절 약제 조성물
WO2014159275A1 (en) *	2013-03-14	2014-10-02	PharmTak, Inc.	Controlled-release pharmaceutical compositions comprising lamotrigine and methods of producing same
CN103920134A (zh) *	2014-05-08	2014-07-16	崔韡	一种治疗儿童眩晕的缓释片及其制备方法
RU2624229C2 (ru) *	2015-12-21	2017-07-03	Общество С Ограниченной Ответственностью "Валента-Интеллект"	Таблетки клозапина с замедленным высвобождением и способ их получения
RU2613192C1 (ru) *	2016-02-18	2017-03-15	Общество С Ограниченной Ответственностью "Валента-Интеллект"	Таблетки клозапина с пролонгированным высвобождением
BR112019016118A2 (pt) *	2017-02-03	2020-07-14	Jubilant Generics Limited	forma farmacêutica de dosagem de suspensão oral de lamotrigina
MX2020002078A (es)	2017-08-24	2020-09-21	Adamas Pharma Llc	Composiciones de amantadina, preparaciones de estas y métodos de uso.
CN111278990A (zh) *	2017-10-27	2020-06-12	长庚医疗财团法人林口长庚纪念医院	评估抗癫痫药物拉莫三嗪引发皮肤药物不良反应风险的方法、其检测试剂和其用途
US10213394B1 (en)	2018-02-15	2019-02-26	Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság	Composition and method for treating neurological disease
US20190247331A1 (en)	2018-02-15	2019-08-15	Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság	Composition and method for treating neurological disease
US10213393B1 (en)	2018-02-15	2019-02-26	Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság	Composition and method for treating neurological disease
US11717501B2 (en) *	2018-04-25	2023-08-08	Neurocentria, Inc.	Magnesium threonate compositions and uses thereof
CN114948868B (zh) *	2021-04-16	2023-04-14	上海奥科达医药科技股份有限公司	一种拉莫三嗪水合物的晶体形式、其制备方法及包含其的组合物
CN116942606A (zh) *	2022-04-18	2023-10-27	上海奥科达医药科技股份有限公司	拉莫三嗪悬浮液和干混悬剂的制备方法

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DK1524981T3 (da) *	2002-07-29	2009-06-22	Glaxo Group Ltd	Sammensætninger med vedvarende frigivelse indeholdende lamotrigin

2003
- 2003-07-28 DK DK03766343T patent/DK1524981T3/da active
- 2003-07-28 WO PCT/EP2003/008368 patent/WO2004012741A1/en not_active Ceased
- 2003-07-28 DE DE60326590T patent/DE60326590D1/de not_active Expired - Lifetime
- 2003-07-28 AU AU2003260336A patent/AU2003260336C1/en not_active Expired
- 2003-07-28 CA CA002493301A patent/CA2493301A1/en not_active Withdrawn
- 2003-07-28 KR KR1020057001633A patent/KR100882707B1/ko not_active Expired - Lifetime
- 2003-07-28 NZ NZ537885A patent/NZ537885A/en not_active IP Right Cessation
- 2003-07-28 BR BRPI0313148A patent/BRPI0313148B8/pt not_active IP Right Cessation
- 2003-07-28 EP EP03766343A patent/EP1524981B1/en not_active Expired - Lifetime
- 2003-07-28 MY MYPI20032831A patent/MY141049A/en unknown
- 2003-07-28 RU RU2005105353/14A patent/RU2325163C2/ru active
- 2003-07-28 CN CNB038223716A patent/CN100363007C/zh not_active Expired - Lifetime
- 2003-07-28 SI SI200331585T patent/SI1524981T1/sl unknown
- 2003-07-28 PL PL374982A patent/PL213565B1/pl unknown
- 2003-07-28 ES ES03766343T patent/ES2323268T3/es not_active Expired - Lifetime
- 2003-07-28 JP JP2004525362A patent/JP4744142B2/ja not_active Expired - Lifetime
- 2003-07-28 MX MXPA05001243A patent/MXPA05001243A/es active IP Right Grant
- 2003-07-28 AT AT03766343T patent/ATE424827T1/de active
- 2003-07-28 PT PT03766343T patent/PT1524981E/pt unknown
- 2003-07-28 AR AR20030102702A patent/AR040709A1/es not_active Application Discontinuation
- 2003-07-28 TW TW092120477A patent/TWI342213B/zh not_active IP Right Cessation
- 2003-07-29 US US10/629,177 patent/US20050032799A1/en not_active Abandoned
2005
- 2005-01-20 IL IL166424A patent/IL166424A/en unknown
- 2005-01-28 MA MA28074A patent/MA27509A1/fr unknown
- 2005-01-28 CO CO05007005A patent/CO5680405A2/es not_active Application Discontinuation
- 2005-02-22 NO NO20050948A patent/NO334221B1/no not_active IP Right Cessation
- 2005-02-23 IS IS7707A patent/IS2681B/is unknown
2009
- 2009-05-29 CY CY20091100580T patent/CY1109119T1/el unknown
2010
- 2010-10-15 JP JP2010232745A patent/JP2011057683A/ja active Pending

Also Published As

Publication number	Publication date
JP2011057683A (ja)	2011-03-24
BRPI0313148B8 (pt)	2021-05-25
MA27509A1 (fr)	2005-09-01
BR0313148A (pt)	2005-07-12
RU2005105353A (ru)	2005-10-27
HK1077003A1 (en)	2006-02-03
PL374982A1 (en)	2005-11-14
PL213565B1 (pl)	2013-03-29
EP1524981A1 (en)	2005-04-27
NO20050948L (no)	2005-02-22
EP1524981B1 (en)	2009-03-11
AU2003260336A1 (en)	2004-02-23
CN100363007C (zh)	2008-01-23
IS2681B (is)	2010-09-15
WO2004012741A1 (en)	2004-02-12
RU2325163C2 (ru)	2008-05-27
JP2005538113A (ja)	2005-12-15
BRPI0313148B1 (pt)	2019-08-20
KR100882707B1 (ko)	2009-02-06
ATE424827T1 (de)	2009-03-15
NO334221B1 (no)	2014-01-13
AU2003260336C1 (en)	2008-05-29
KR20050026054A (ko)	2005-03-14
MXPA05001243A (es)	2005-06-08
AR040709A1 (es)	2005-04-13
ES2323268T3 (es)	2009-07-10
CA2493301A1 (en)	2004-02-12
CO5680405A2 (es)	2006-09-29
DE60326590D1 (de)	2009-04-23
CN1681509A (zh)	2005-10-12
IS7707A (is)	2005-02-23
NZ537885A (en)	2007-11-30
IL166424A0 (en)	2006-01-15
CY1109119T1 (el)	2014-07-02
SI1524981T1 (sl)	2009-08-31
TW200418484A (en)	2004-10-01
IL166424A (en)	2010-12-30
MY141049A (en)	2010-02-25
JP4744142B2 (ja)	2011-08-10
PT1524981E (pt)	2009-06-17
TWI342213B (en)	2011-05-21
US20050032799A1 (en)	2005-02-10

Publication	Publication Date	Title
DK1524981T3 (da)	2009-06-22	Sammensætninger med vedvarende frigivelse indeholdende lamotrigin
FI20010780A0 (fi)	2001-04-12	Parannetut koostumukset
ATE368042T1 (de)	2007-08-15	Cephemverbindungen
IS7471A (is)	2004-10-15	Ný efnasambönd
DE10393374D2 (de)	2005-09-01	Zusammensetzung
IS7879A (is)	2005-06-02	Ný efnasambönd
ITMI20011062A0 (it)	2001-05-22	Composizioni fluoroelastomeriche
IS7381A (is)	2004-08-03	Efnasambönd
EP1559433A4 (en)	2009-11-04	STABILIZED COMPOSITION
IS7414A (is)	2004-08-19	Oxó-azabísýklísk efnasambönd
DK1561472T3 (da)	2013-11-11	Faststofsammensætning
ITMI20011061A0 (it)	2001-05-22	Composizioni fluoroelastomeriche
ITMI20011060A0 (it)	2001-05-22	Composizioni fluoroelastomeriche
DE60320902D1 (de)	2008-06-26	Zusammensetzungen mit ausgelöster Freisetzung
NO20045659L (no)	2004-12-27	Forbindelser
IS7793A (is)	2005-04-11	Nýtt efnasamband
IS7827A (is)	2005-04-27	Ný efnasambönd
IS7794A (is)	2005-04-11	Nýtt efnasamband
ITMI20011059A0 (it)	2001-05-22	Composizioni fluoroelastomeriche
SE0500163L (sv)	2005-01-24	Sammansättning
DK1487778T3 (da)	2012-08-06	Substituerede 4 aminocyclohexanoler
ATE393811T1 (de)	2008-05-15	Waschmittelzusammensetzungen
EP1561467A4 (en)	2008-06-25	COMPOSITION FOR RECOVERING DAMAGED SKIN
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NO20044164L (no)	2004-09-30	Farmasoytiske sammensetninger