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NO20045659L - Forbindelser - Google Patents

Forbindelser

Info

Publication number
NO20045659L
NO20045659L NO20045659A NO20045659A NO20045659L NO 20045659 L NO20045659 L NO 20045659L NO 20045659 A NO20045659 A NO 20045659A NO 20045659 A NO20045659 A NO 20045659A NO 20045659 L NO20045659 L NO 20045659L
Authority
NO
Norway
Prior art keywords
compounds
Prior art date
Application number
NO20045659A
Other languages
English (en)
Other versions
NO330118B1 (no
Inventor
Andrew Derrick Gribble
Andrew Hele Payne
Graham Walker
Andrew P Lightfoot
Ian Thomson Forbes
Vincenzo Garzya
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0212401A external-priority patent/GB0212401D0/en
Priority claimed from GB0230053A external-priority patent/GB0230053D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO20045659L publication Critical patent/NO20045659L/no
Publication of NO330118B1 publication Critical patent/NO330118B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO20045659A 2002-05-29 2004-12-27 Nye forbindelser, farmasoytisk sammensetning, anvendelse NO330118B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0212401A GB0212401D0 (en) 2002-05-29 2002-05-29 Compounds
GB0230053A GB0230053D0 (en) 2002-12-23 2002-12-23 Compounds
PCT/EP2003/005727 WO2003099786A2 (en) 2002-05-29 2003-05-28 Aromatic sulfones and their medical use

Publications (2)

Publication Number Publication Date
NO20045659L true NO20045659L (no) 2004-12-27
NO330118B1 NO330118B1 (no) 2011-02-21

Family

ID=29585827

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20045659A NO330118B1 (no) 2002-05-29 2004-12-27 Nye forbindelser, farmasoytisk sammensetning, anvendelse

Country Status (25)

Country Link
US (2) US7504392B2 (no)
EP (1) EP1511727B1 (no)
JP (1) JP4268126B2 (no)
KR (1) KR20050013196A (no)
AR (1) AR040126A1 (no)
AT (1) ATE354566T1 (no)
AU (1) AU2003232846B9 (no)
BR (1) BR0311315A (no)
CA (1) CA2486962A1 (no)
CY (1) CY1107053T1 (no)
DE (1) DE60311986T2 (no)
DK (1) DK1511727T3 (no)
ES (1) ES2279965T3 (no)
IL (1) IL165330A0 (no)
IS (1) IS2482B (no)
MX (1) MXPA04011945A (no)
MY (1) MY133587A (no)
NO (1) NO330118B1 (no)
NZ (1) NZ536694A (no)
PL (1) PL374081A1 (no)
PT (1) PT1511727E (no)
RU (1) RU2327690C2 (no)
SI (1) SI1511727T1 (no)
TW (1) TWI281914B (no)
WO (1) WO2003099786A2 (no)

Families Citing this family (19)

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MY133587A (en) 2002-05-29 2007-11-30 Glaxo Group Ltd Aromatic sulfones and their medical use
MXPA04012704A (es) * 2002-06-19 2005-03-23 Schering Corp Agonistas de los receptores canabinoides.
GB0319235D0 (en) * 2003-08-15 2003-09-17 Glaxo Group Ltd Novel compounds
GB0327737D0 (en) * 2003-11-28 2003-12-31 Glaxo Group Ltd Novel compounds
GB0327741D0 (en) * 2003-11-28 2003-12-31 Glaxo Group Ltd Novel compounds
GB0327740D0 (en) * 2003-11-28 2003-12-31 Glaxo Group Ltd Novel compounds
GB0327738D0 (en) * 2003-11-28 2003-12-31 Glaxo Group Ltd Novel compound
GB0505437D0 (en) * 2005-03-17 2005-04-20 Merck Sharp & Dohme Therapeutic agents
GB0505725D0 (en) * 2005-03-19 2005-04-27 Merck Sharp & Dohme Therapeutic agents
US7671023B2 (en) * 2005-03-31 2010-03-02 Amylin Pharmaceuticals, Inc. Amylin agonist for treating depression, anxiety disorder and schizophrenia
GB0510599D0 (en) * 2005-05-24 2005-06-29 Glaxo Group Ltd Novel compounds
GB0603087D0 (en) * 2006-02-15 2006-03-29 Glaxo Group Ltd Novel use
US20070293475A1 (en) * 2006-06-20 2007-12-20 Alcon Manufacturing Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
PT2054416E (pt) * 2006-08-04 2011-04-06 Merz Pharma Gmbh & Co Kgaa Pirazolopirimidinas substituídas, um processo para a sua preparação e a sua utilização como medicamento
US8314090B2 (en) * 2008-11-06 2012-11-20 Ventirx Pharmaceuticals, Inc. Methods of synthesis of benzazepine derivatives
US20180228811A1 (en) * 2014-12-12 2018-08-16 The Schepens Eye Research Institute, Inc. Gdnf induction for the treatment of retinal disorders
US11124497B1 (en) 2020-04-17 2021-09-21 Pardes Biosciences, Inc. Inhibitors of cysteine proteases and methods of use thereof
US11174231B1 (en) 2020-06-09 2021-11-16 Pardes Biosciences, Inc. Inhibitors of cysteine proteases and methods of use thereof
US11351149B2 (en) 2020-09-03 2022-06-07 Pfizer Inc. Nitrile-containing antiviral compounds

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JPH01503233A (ja) 1986-10-28 1989-11-02 スミス・クライン・アンド・フレンチ・ラボラトリース・リミテッド 製薬活性化合物
DE3869446D1 (de) * 1987-03-10 1992-04-30 Lion Corp Desodorierungsmittel.
EP0285287A3 (en) * 1987-03-23 1990-08-16 Smithkline Beecham Corporation 3-benzazepine compounds for use in treating gastrointestinal motility disorders
GB8717374D0 (en) 1987-07-22 1987-08-26 Smith Kline French Lab Pharmaceutically active compounds
US5032604A (en) 1989-12-08 1991-07-16 Merck & Co., Inc. Class III antiarrhythmic agents
GB9127041D0 (en) 1991-12-20 1992-02-19 Fujisawa Pharmaceutical Co New use
GB9212308D0 (en) 1992-06-10 1992-07-22 Ici Plc Therapeutic compositions
CA2184101C (en) 1994-02-25 2005-11-22 Susumu Nakagawa Carbapenem derivatives
US5684195A (en) 1994-07-14 1997-11-04 G. D. Searle & Co. Method of preparing sulfmonamides from sulfones
EP0828754B1 (en) 1995-05-29 2005-02-02 Pfizer Inc. Dipeptides which promote release of growth hormone
DE19548785A1 (de) 1995-12-27 1997-07-03 Basf Ag Saure Polyazofarbstoffe
ATE232850T1 (de) 1996-05-11 2003-03-15 Smithkline Beecham Plc Tetrahydroisoquinoline derivate als modulatoren von dopamine d3 rezeptoren
EP0922035B1 (en) 1996-08-14 2001-02-07 Smithkline Beecham Plc Tetrahydroisoquinoline derivatives and their pharmaceutical use
DE19638486A1 (de) 1996-09-20 1998-03-26 Basf Ag Hetaroylderivate
DE19638484A1 (de) 1996-09-20 1998-03-26 Basf Ag Hetaroylderivate
NZ500590A (en) 1997-04-22 2001-11-30 Cocensys Inc Carbocyclic and heterocyclic substituted semicarbazones and thiosemicarbazones and the use thereof
GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
EP0937723A1 (de) 1998-02-18 1999-08-25 Roche Diagnostics GmbH Neue Sulfonamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
GB9804734D0 (en) 1998-03-05 1998-04-29 Pfizer Ltd Compounds
US6344486B1 (en) 1998-04-03 2002-02-05 3-Dimensional Pharmaceuticals, Inc. Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors
DE69914931T2 (de) 1998-10-09 2004-12-16 Janssen Pharmaceutica N.V. 4,5-dehydroisoxazole derivate und ihre pharmazeutische verwendung
TWI274750B (en) 1999-01-12 2007-03-01 Abbott Gmbh & Co Kg Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same
RU2001126721A (ru) 1999-03-03 2004-02-20 Дзе Проктер Энд Гэмбл Компани (US) Алкенил-и алкинилсодержащие ингибиторы металлопротезы
JP2003500386A (ja) 1999-05-24 2003-01-07 シーオーアール セラピューティクス インコーポレイテッド Xa因子阻害剤
US6531478B2 (en) 2000-02-24 2003-03-11 Cheryl P. Kordik Amino pyrazole derivatives useful for the treatment of obesity and other disorders
ATE310728T1 (de) 2000-05-11 2005-12-15 Bristol Myers Squibb Co Tetrahydroisochinolin-analoga als wachstumshormon-sekretagoga
US6416458B1 (en) * 2000-07-12 2002-07-09 Therion Research Inc. Therapeutic flexible magnetic sheet and method
CA2390535C (en) 2000-09-14 2008-12-02 Edmund Gene Butts Curling garment brush retainer
DE10053799A1 (de) 2000-10-30 2002-05-08 Bayer Ag Verwendung von Tetrahydroisochinolinsulfonamiden
AU2303402A (en) 2000-11-14 2002-05-27 Smithkline Beecham Plc Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
US7256201B2 (en) 2000-12-07 2007-08-14 Astrazeneca Ab Selective estrogen receptor-β ligands
GB0111186D0 (en) 2001-05-08 2001-06-27 Smithkline Beecham Plc Novel compounds
JP2005518414A (ja) 2001-12-21 2005-06-23 スミスクライン ビーチャム パブリック リミテッド カンパニー ドーパミン受容体のモジュレーターとしての7−スルホニル−3−ベンゾアゼピン誘導体およびcns障害の治療のためのその使用
ATE323680T1 (de) 2002-02-13 2006-05-15 Glaxo Group Ltd 7-arylsulfonamid-2,3,4,5-tetrahydro-1h- benzo¬däazepine mit 5-ht6 rezeptor affinität zur behandlung von zentralnervensystemerkrankungen
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PL371344A1 (en) 2002-02-13 2005-06-13 Glaxo Group Limited Benzenesulfonamide derivatives as antipsychotic agents
GB0210762D0 (en) 2002-05-10 2002-06-19 Glaxo Group Ltd Compounds
MY133587A (en) 2002-05-29 2007-11-30 Glaxo Group Ltd Aromatic sulfones and their medical use
GB0212399D0 (en) 2002-05-29 2002-07-10 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
DK1511727T3 (da) 2007-06-11
ES2279965T3 (es) 2007-09-01
AU2003232846A1 (en) 2003-12-12
WO2003099786A3 (en) 2004-09-02
PL374081A1 (en) 2005-09-19
NZ536694A (en) 2006-11-30
DE60311986D1 (de) 2007-04-05
IS7577A (is) 2004-12-01
US7504392B2 (en) 2009-03-17
CY1107053T1 (el) 2012-10-24
NO330118B1 (no) 2011-02-21
MXPA04011945A (es) 2005-03-31
BR0311315A (pt) 2005-03-01
EP1511727A2 (en) 2005-03-09
AU2003232846B2 (en) 2007-02-22
RU2327690C2 (ru) 2008-06-27
CA2486962A1 (en) 2003-12-04
TWI281914B (en) 2007-06-01
MY133587A (en) 2007-11-30
JP2005531579A (ja) 2005-10-20
US20050261279A1 (en) 2005-11-24
SI1511727T1 (sl) 2007-06-30
HK1075050A1 (en) 2005-12-02
IL165330A0 (en) 2006-01-15
JP4268126B2 (ja) 2009-05-27
ATE354566T1 (de) 2007-03-15
IS2482B (is) 2008-12-15
RU2004138588A (ru) 2005-06-27
EP1511727B1 (en) 2007-02-21
US20080269197A1 (en) 2008-10-30
DE60311986T2 (de) 2007-10-31
TW200406381A (en) 2004-05-01
AR040126A1 (es) 2005-03-16
KR20050013196A (ko) 2005-02-03
WO2003099786A2 (en) 2003-12-04
AU2003232846B9 (en) 2007-04-19
PT1511727E (pt) 2007-05-31

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