DK1583756T3 - Thiophencarboxamider som inhibitorer af enzymet IKK-2 - Google Patents

Thiophencarboxamider som inhibitorer af enzymet IKK-2

Info

Publication number: DK1583756T3
Authority: DK; Denmark
Prior art keywords: inhibitors; thiophene carboxamides; ikk; enzyme; enzyme ikk
Prior art date: 2003-01-15

Application number

DK04701632T

Other languages

Danish (da)

English (en)

Inventor

Andrew David Morley

Jeffrey P Poyser

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-15

Filing date

2004-01-13

Publication date

2007-12-17

2004-01-13 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2007-12-17 Application granted granted Critical

2007-12-17 Publication of DK1583756T3 publication Critical patent/DK1583756T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Hematology (AREA)
Physical Education & Sports Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Obesity (AREA)
Dermatology (AREA)
Virology (AREA)
Neurology (AREA)
Endocrinology (AREA)
AIDS & HIV (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Transplantation (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Tropical Medicine & Parasitology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)

DK04701632T 2003-01-15 2004-01-13 Thiophencarboxamider som inhibitorer af enzymet IKK-2 DK1583756T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0300091A SE0300091D0 (sv)	2003-01-15	2003-01-15	Novel compounds
PCT/GB2004/000106 WO2004063185A1 (fr)	2003-01-15	2004-01-13	Thiophene carboxamides utilises en tant qu'inhibiteurs de l'enzyme ikk-2

Publications (1)

Publication Number	Publication Date
DK1583756T3 true DK1583756T3 (da)	2007-12-17

Family

ID=20290126

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04701632T DK1583756T3 (da)	2003-01-15	2004-01-13	Thiophencarboxamider som inhibitorer af enzymet IKK-2

Country Status (20)

Country	Link
US (2)	US7553868B2 (fr)
EP (1)	EP1583756B9 (fr)
JP (1)	JP4568714B2 (fr)
KR (1)	KR20050098248A (fr)
CN (1)	CN1315820C (fr)
AT (1)	ATE374762T1 (fr)
BR (1)	BRPI0406774A (fr)
CA (1)	CA2512336A1 (fr)
CY (1)	CY1107817T1 (fr)
DE (1)	DE602004009283T2 (fr)
DK (1)	DK1583756T3 (fr)
ES (1)	ES2293206T3 (fr)
IL (1)	IL169478A (fr)
MX (1)	MXPA05007340A (fr)
NO (1)	NO20053810L (fr)
NZ (1)	NZ541219A (fr)
PT (1)	PT1583756E (fr)
SE (1)	SE0300091D0 (fr)
WO (1)	WO2004063185A1 (fr)
ZA (1)	ZA200505190B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0003154D0 (en) *	2000-02-12	2000-04-05	Astrazeneca Uk Ltd	Novel compounds
SE0102616D0 (sv) *	2001-07-25	2001-07-25	Astrazeneca Ab	Novel compounds
SE0300091D0 (sv)	2003-01-15	2003-01-15	Astrazeneca Ab	Novel compounds
SE0300092D0 (sv) *	2003-01-15	2003-01-15	Astrazeneca Ab	Novel compounds
BRPI0413585A (pt)	2003-08-15	2006-10-17	Astrazeneca Ab	composto ou sal farmaceuticamente aceitável ou um precursor hidrolisável in vivo deste, uso de um composto ou um sal deste farmaceuticamente aceitável, métodos para o tratamento de cáncer, e de infecções associadas com cáncer, composição farmacêutica, e, processo para preparação e uso de um composto ou um sal farmacêuticamente aceitável ou um precursor hidrolisável in vivo
DE602004031777D1 (en) *	2004-01-05	2011-04-21	Astrazeneca Ab	Thiophenderivate als chk-1-inhibitoren
WO2005105777A1 (fr) *	2004-05-05	2005-11-10	Pharmacia & Upjohn Company Llc	Composes d'amide a substitution de thiophene pour le traitement de l'inflammation.
DK2119703T3 (da) *	2007-01-15	2013-01-14	Santen Pharmaceutical Co Ltd	Nyt indolderivat med inhiberende virkning på I-B-kinase.
JPWO2009096198A1 (ja) *	2008-02-01	2011-05-26	一般社団法人ファルマＩｐ	新規ビアリール誘導体
MX2010011501A (es) *	2008-04-23	2010-11-30	Chroma Therapeutics Ltd	Inhibidores de proteina cinasa de serina-treonina ikk-beta.
US8445529B2 (en) *	2008-07-14	2013-05-21	Santen Pharmaceutical Co., Ltd.	Indole derivative having, carbamoyl group, ureido group and substituted oxy group
GB0907120D0 (en) *	2009-04-24	2009-06-03	Chroma Therapeutics Ltd	Inhibitors of IKK-ß serine-threonine protein kinase
GB0913345D0 (en)	2009-07-31	2009-09-16	Astrazeneca Ab	New combination 802
WO2011061527A1 (fr)	2009-11-17	2011-05-26	Astrazeneca Ab	Combinaisons qui comprennent un modulateur du récepteur glucocorticoïde, destinées au traitement de maladies respiratoires
GB201016912D0 (en)	2010-10-07	2010-11-24	Astrazeneca Ab	Novel combination
GB201021992D0 (en)	2010-12-23	2011-02-02	Astrazeneca Ab	Compound
GB201021979D0 (en)	2010-12-23	2011-02-02	Astrazeneca Ab	New compound

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1468012A (en) *	1973-08-09	1977-03-23	Beecham Group Ltd	2-amino-3-carboxy-thiophene derivatives
DE3529247A1 (de)	1985-05-17	1986-11-20	Bayer Ag, 5090 Leverkusen	Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung
GB2195634B (en)	1986-10-01	1990-08-15	Roussel Lab Ltd	Thiophene derivatives
US5258357A (en) *	1989-10-07	1993-11-02	Basf Aktiengesellschaft	Carboxamides, their preparation and their use as herbicides
US5378703A (en) *	1990-04-09	1995-01-03	Alcon Laboratories, Inc.	Sulfonamides useful as carbonic anhydrase inhibitors
US5571810A (en) *	1990-06-11	1996-11-05	Fujisawa Pharmaceutical Co., Ltd.	Thiophene derivatives
US5514801A (en) *	1992-12-29	1996-05-07	Monsanto Company	Cyclic sulfone containing retroviral protease inhibitors
US6417202B1 (en)	1996-07-11	2002-07-09	Pfizer Inc.	Pyridylpyrrole compounds useful as interleukin-and TNF antagonists
PT853083E (pt)	1997-01-06	2001-12-28	Pfizer	Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica
US6809088B2 (en) *	1997-03-24	2004-10-26	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.)	Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them
AU6959898A (en) *	1997-04-11	1998-11-11	David J. Grainger	Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
US6037340A (en)	1997-05-28	2000-03-14	Cadus Pharmaceutical Corporation	Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds
DE19744026A1 (de)	1997-10-06	1999-04-08	Hoechst Marion Roussel De Gmbh	Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln
WO1999046244A1 (fr)	1998-03-12	1999-09-16	Novo Nordisk A/S	Modulateurs de proteine tyrosine phosphatases (ptpases)
WO2000002851A1 (fr) *	1998-07-08	2000-01-20	Aventis Pharma Deutschland Gmbh	N-arylamides d'acide sulfonylaminocarboxylique a substitution soufre, preparation et utilisation de ces derniers, preparations pharmaceutiques contenant ces composes
HN2000000051A (es) *	1999-05-19	2001-02-02	Pfizer Prod Inc	Derivados heterociclicos utiles como agentes anticancerosos
GB0003154D0 (en) *	2000-02-12	2000-04-05	Astrazeneca Uk Ltd	Novel compounds
JP5074653B2 (ja) *	2000-03-29	2012-11-14	サイクラセルリミテッド	２−置換４−ヘテロアリール−ピリミジンおよび増殖性障害におけるその使用
US6414013B1 (en) *	2000-06-19	2002-07-02	Pharmacia & Upjohn S.P.A.	Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention
AU2002211663A1 (en)	2000-10-12	2002-04-22	Smith Kline Beecham Corporation	Nf-$g(k)b inhibitors
US7122544B2 (en) *	2000-12-06	2006-10-17	Signal Pharmaceuticals, Llc	Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto
US20050238911A1 (en)	2001-03-16	2005-10-27	Sturley David K	Non-powered luminous panels and devices and method of manufacture
US6713638B2 (en) *	2001-05-18	2004-03-30	Joel M. Linden	2-amino-3-aroyl-4,5 alkylthiophenes: agonist allosteric enhancers at human A1 adenosine receptors
PL395097A1 (pl) *	2001-06-11	2011-10-10	Vertex Pharmaceuticals (Canada) Incorporated	Sposób wytwarzania związku o wzorze A stanowiącego pochodną tiofenu
SE0102616D0 (sv) *	2001-07-25	2001-07-25	Astrazeneca Ab	Novel compounds
SE0102617D0 (sv)	2001-07-25	2001-07-25	Astrazeneca Ab	Novel compounds
WO2003029241A1 (fr)	2001-10-04	2003-04-10	Smithkline Beecham Corporation	Inhibiteurs de chk1 kinase
JP2005506334A (ja) *	2001-10-04	2005-03-03	スミスクライン・ビーチャム・コーポレイション	ＮＦ−κＢ阻害剤
WO2003028731A1 (fr)	2001-10-04	2003-04-10	Smithkline Beecham Corporation	Inhibiteurs de kinase chk1
TWI281916B (en) *	2001-10-25	2007-06-01	Lilly Co Eli	Antitumor compounds and methods
US6835745B2 (en) *	2002-01-15	2004-12-28	Wyeth	Phenyl substituted thiophenes as estrogenic agents
US7196106B2 (en) *	2002-11-05	2007-03-27	Merck & Co., Inc	Cyanothiophene derivatives, compositions containing such compounds and methods of use
SE0300092D0 (sv) *	2003-01-15	2003-01-15	Astrazeneca Ab	Novel compounds
SE0300091D0 (sv)	2003-01-15	2003-01-15	Astrazeneca Ab	Novel compounds

2003
- 2003-01-15 SE SE0300091A patent/SE0300091D0/xx unknown
2004
- 2004-01-13 KR KR1020057013033A patent/KR20050098248A/ko not_active Ceased
- 2004-01-13 MX MXPA05007340A patent/MXPA05007340A/es active IP Right Grant
- 2004-01-13 CN CNB2004800023046A patent/CN1315820C/zh not_active Expired - Fee Related
- 2004-01-13 WO PCT/GB2004/000106 patent/WO2004063185A1/fr not_active Ceased
- 2004-01-13 AT AT04701632T patent/ATE374762T1/de active
- 2004-01-13 NZ NZ541219A patent/NZ541219A/en not_active IP Right Cessation
- 2004-01-13 US US10/542,044 patent/US7553868B2/en not_active Expired - Fee Related
- 2004-01-13 ES ES04701632T patent/ES2293206T3/es not_active Expired - Lifetime
- 2004-01-13 JP JP2006500206A patent/JP4568714B2/ja not_active Expired - Fee Related
- 2004-01-13 EP EP04701632A patent/EP1583756B9/fr not_active Expired - Lifetime
- 2004-01-13 PT PT04701632T patent/PT1583756E/pt unknown
- 2004-01-13 DE DE602004009283T patent/DE602004009283T2/de not_active Expired - Lifetime
- 2004-01-13 CA CA002512336A patent/CA2512336A1/fr not_active Abandoned
- 2004-01-13 BR BR0406774-6A patent/BRPI0406774A/pt not_active IP Right Cessation
- 2004-01-13 DK DK04701632T patent/DK1583756T3/da active
2005
- 2005-06-27 ZA ZA200505190A patent/ZA200505190B/en unknown
- 2005-06-29 IL IL169478A patent/IL169478A/en not_active IP Right Cessation
- 2005-08-12 NO NO20053810A patent/NO20053810L/no not_active Application Discontinuation
2007
- 2007-11-29 CY CY20071101528T patent/CY1107817T1/el unknown
2009
- 2009-05-04 US US12/435,054 patent/US20090215829A1/en not_active Abandoned

Also Published As

Publication number	Publication date
PT1583756E (pt)	2007-12-03
KR20050098248A (ko)	2005-10-11
IL169478A0 (en)	2009-02-11
CA2512336A1 (fr)	2004-07-29
EP1583756B1 (fr)	2007-10-03
CN1738812A (zh)	2006-02-22
US7553868B2 (en)	2009-06-30
WO2004063185A1 (fr)	2004-07-29
US20060111431A1 (en)	2006-05-25
WO2004063185A8 (fr)	2004-09-23
MXPA05007340A (es)	2005-09-30
US20090215829A1 (en)	2009-08-27
BRPI0406774A (pt)	2005-12-27
ES2293206T3 (es)	2008-03-16
CN1315820C (zh)	2007-05-16
JP2006515355A (ja)	2006-05-25
EP1583756A1 (fr)	2005-10-12
NO20053810L (no)	2005-10-12
ATE374762T1 (de)	2007-10-15
IL169478A (en)	2010-02-17
CY1107817T1 (el)	2013-06-19
ZA200505190B (en)	2006-04-26
EP1583756B9 (fr)	2008-01-09
DE602004009283T2 (de)	2008-07-10
NZ541219A (en)	2008-03-28
AU2004203967A1 (en)	2004-07-29
HK1082250A1 (en)	2006-06-02
SE0300091D0 (sv)	2003-01-15
NO20053810D0 (no)	2005-08-12
JP4568714B2 (ja)	2010-10-27
DE602004009283D1 (de)	2007-11-15

Publication	Publication Date	Title
CY1107817T1 (el)	2013-06-19	Καρβοξαμιδια θειοφαινιου ως αναστολεις του ενζυμου ικκ-2
DK1261600T3 (da)	2004-08-16	Heteroaromatiske carboxamidderivater og deres anvendelse som inhibitorer af enzymet IKK-2
BR0211473A (pt)	2004-10-26	Novos compostos
MXPA04000755A (es)	2004-04-20	Nuevos compuestos.
EA200500203A1 (ru)	2005-08-25	Новый способ синтеза и новая кристаллическая форма агомелатина и фармацевтические композиции, которые её содержат
EA200700192A1 (ru)	2007-06-29	Производные фталазина в качестве ингибиторов parp
SE0202133D0 (sv)	2002-07-08	Novel compounds
SE0302811D0 (sv)	2003-10-23	Novel compounds
ATE539073T1 (de)	2012-01-15	Heterocyclylalkylderivate als neue inhibitoren von histondeacetylase
SE0301653D0 (sv)	2003-06-05	Novel compounds
TW200621262A (en)	2006-07-01	New dihydropteridione derivatives, process for their manufacture and their use as medicament
SE0300092D0 (sv)	2003-01-15	Novel compounds
SE0303541D0 (sv)	2003-12-22	New compounds
ATE449069T1 (de)	2009-12-15	Aminopropanolderivate
DK1789398T3 (da)	2011-01-24	2-amino-quinazolin derivater anvendelige som inhibitorer af B-sekretase (BACE)
SV2004001555A (es)	2004-03-19	Difenilazetidinonas cationicamente sustituidas, procesos para su preparacion, medicamentos que contienen estos compuestos y sus usos
SE0400850D0 (sv)	2004-03-31	Novel Compounds
ATE431333T1 (de)	2009-05-15	Amino-propanolderivate
SE0403086D0 (sv)	2004-12-17	Compounds
SE0303090D0 (sv)	2003-11-20	Novel compounds
TNSN05291A1 (en)	2007-07-10	Sulfamate benzothiophene derivatives as steroid sulfatase inhibitors
DK1819704T3 (da)	2008-10-20	Pyrrolopyridin-2-carboxylsyre-amid-derivat anvendelig som inhibitor af glycogenphosphorylase
ATE501127T1 (de)	2011-03-15	Neue cysteinproteasehemmer und ihre therapeutische anwendung
ATE374751T1 (de)	2007-10-15	3,4-dihydro-1h-chinolin-2-onderivate als norepinephrin-wiederaufnahme-hemmern
YU90403A (sh)	2006-05-25	Naftotiazinski pozitivno alosterični modulatori ampa receptora (paarm)