SE0300091D0 - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- SE0300091D0 SE0300091D0 SE0300091A SE0300091A SE0300091D0 SE 0300091 D0 SE0300091 D0 SE 0300091D0 SE 0300091 A SE0300091 A SE 0300091A SE 0300091 A SE0300091 A SE 0300091A SE 0300091 D0 SE0300091 D0 SE 0300091D0
- Authority
- SE
- Sweden
- Prior art keywords
- novel compounds
- therapy
- processes
- formula
- preparation
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- DENPQNAWGQXKCU-UHFFFAOYSA-N thiophene-2-carboxamide Chemical class NC(=O)C1=CC=CS1 DENPQNAWGQXKCU-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- AIDS & HIV (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
Priority Applications (24)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0300091A SE0300091D0 (sv) | 2003-01-15 | 2003-01-15 | Novel compounds |
| PCT/GB2004/000106 WO2004063185A1 (en) | 2003-01-15 | 2004-01-13 | Thiophene carboxamides as inhibitors of the enzyme ikk-2 |
| AU2004203967A AU2004203967B2 (en) | 2003-01-15 | 2004-01-13 | Thiophene carboxamides as inhibitors of the enzyme IKK-2 |
| PT04701632T PT1583756E (pt) | 2003-01-15 | 2004-01-13 | Tiofenocarboxamidas como inibidores da enzima ikk-2 |
| DK04701632T DK1583756T3 (da) | 2003-01-15 | 2004-01-13 | Thiophencarboxamider som inhibitorer af enzymet IKK-2 |
| SI200430502T SI1583756T1 (sl) | 2003-01-15 | 2004-01-13 | Tiofenski karboksamidi kot inhibitorji encima IKK-2 |
| BR0406774-6A BRPI0406774A (pt) | 2003-01-15 | 2004-01-13 | Derivados de tiofeno-carboxamida como inibidores da enzima ikk-2 |
| AT04701632T ATE374762T1 (de) | 2003-01-15 | 2004-01-13 | Thiophencarboxamide als inhibitoren des enzyms ikk-2 |
| EP04701632A EP1583756B9 (en) | 2003-01-15 | 2004-01-13 | Thiophene carboxamides as inhibitors of the enzyme ikk-2 |
| HK06103016.8A HK1082250B (en) | 2003-01-15 | 2004-01-13 | Thiophene carboxamides as inhibitors of the enzyme ikk-2 |
| ES04701632T ES2293206T3 (es) | 2003-01-15 | 2004-01-13 | Tiofeno-carboxamidas utilizados como inhibidores de la enzima ikk-2. |
| DE602004009283T DE602004009283T2 (de) | 2003-01-15 | 2004-01-13 | Thiophencarboxamide als inhibitoren des enzyms ikk-2 |
| CA002512336A CA2512336A1 (en) | 2003-01-15 | 2004-01-13 | Thiophene carboxamides as inhibitors of the enzyme ikk-2 |
| JP2006500206A JP4568714B2 (ja) | 2003-01-15 | 2004-01-13 | 酵素ikk−2阻害剤としてのチオフェンカルボキサミド |
| US10/542,044 US7553868B2 (en) | 2003-01-15 | 2004-01-13 | Thiophene carboxamides as inhibitors of the enzyme IKK-2 |
| NZ541219A NZ541219A (en) | 2003-01-15 | 2004-01-13 | Thiophene carboxamides as inhibitors of the enzyme IKK-2 |
| MXPA05007340A MXPA05007340A (es) | 2003-01-15 | 2004-01-13 | Tiofen carboxamidas como inhibidores de enzima ikk-2. |
| CNB2004800023046A CN1315820C (zh) | 2003-01-15 | 2004-01-13 | 作为酶ikk-2抑制剂的噻吩甲酰胺 |
| KR1020057013033A KR20050098248A (ko) | 2003-01-15 | 2004-01-13 | 효소 ikk-2의 저해제로서의 티오펜 카르복사미드 |
| ZA200505190A ZA200505190B (en) | 2003-01-15 | 2005-06-27 | Thiophene carboxamides as inhibitors of the enzyme IKK-2 |
| IL169478A IL169478A (en) | 2003-01-15 | 2005-06-29 | Thiophene carboxamides as inhibitors of the enzyme ikk - 2 |
| NO20053810A NO20053810L (no) | 2003-01-15 | 2005-08-12 | Thiofenkarboksamider som inhibitorer av enzymet IKK-2 |
| CY20071101528T CY1107817T1 (el) | 2003-01-15 | 2007-11-29 | Καρβοξαμιδια θειοφαινιου ως αναστολεις του ενζυμου ικκ-2 |
| US12/435,054 US20090215829A1 (en) | 2003-01-15 | 2009-05-04 | Thiophene carboxamides as inhibitors of the enzyme ikk-2 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0300091A SE0300091D0 (sv) | 2003-01-15 | 2003-01-15 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE0300091D0 true SE0300091D0 (sv) | 2003-01-15 |
Family
ID=20290126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0300091A SE0300091D0 (sv) | 2003-01-15 | 2003-01-15 | Novel compounds |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7553868B2 (xx) |
| EP (1) | EP1583756B9 (xx) |
| JP (1) | JP4568714B2 (xx) |
| KR (1) | KR20050098248A (xx) |
| CN (1) | CN1315820C (xx) |
| AT (1) | ATE374762T1 (xx) |
| BR (1) | BRPI0406774A (xx) |
| CA (1) | CA2512336A1 (xx) |
| CY (1) | CY1107817T1 (xx) |
| DE (1) | DE602004009283T2 (xx) |
| DK (1) | DK1583756T3 (xx) |
| ES (1) | ES2293206T3 (xx) |
| IL (1) | IL169478A (xx) |
| MX (1) | MXPA05007340A (xx) |
| NO (1) | NO20053810L (xx) |
| NZ (1) | NZ541219A (xx) |
| PT (1) | PT1583756E (xx) |
| SE (1) | SE0300091D0 (xx) |
| WO (1) | WO2004063185A1 (xx) |
| ZA (1) | ZA200505190B (xx) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0003154D0 (en) * | 2000-02-12 | 2000-04-05 | Astrazeneca Uk Ltd | Novel compounds |
| SE0102616D0 (sv) * | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
| SE0300091D0 (sv) | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
| SE0300092D0 (sv) * | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
| BRPI0413585A (pt) | 2003-08-15 | 2006-10-17 | Astrazeneca Ab | composto ou sal farmaceuticamente aceitável ou um precursor hidrolisável in vivo deste, uso de um composto ou um sal deste farmaceuticamente aceitável, métodos para o tratamento de cáncer, e de infecções associadas com cáncer, composição farmacêutica, e, processo para preparação e uso de um composto ou um sal farmacêuticamente aceitável ou um precursor hidrolisável in vivo |
| DE602004031777D1 (en) * | 2004-01-05 | 2011-04-21 | Astrazeneca Ab | Thiophenderivate als chk-1-inhibitoren |
| WO2005105777A1 (en) * | 2004-05-05 | 2005-11-10 | Pharmacia & Upjohn Company Llc | Substituted thiophene amide compounds for the treatment of inflammation |
| DK2119703T3 (da) * | 2007-01-15 | 2013-01-14 | Santen Pharmaceutical Co Ltd | Nyt indolderivat med inhiberende virkning på I-B-kinase. |
| JPWO2009096198A1 (ja) * | 2008-02-01 | 2011-05-26 | 一般社団法人ファルマIp | 新規ビアリール誘導体 |
| MX2010011501A (es) * | 2008-04-23 | 2010-11-30 | Chroma Therapeutics Ltd | Inhibidores de proteina cinasa de serina-treonina ikk-beta. |
| US8445529B2 (en) * | 2008-07-14 | 2013-05-21 | Santen Pharmaceutical Co., Ltd. | Indole derivative having, carbamoyl group, ureido group and substituted oxy group |
| GB0907120D0 (en) * | 2009-04-24 | 2009-06-03 | Chroma Therapeutics Ltd | Inhibitors of IKK-ß serine-threonine protein kinase |
| GB0913345D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | New combination 802 |
| WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
| GB201016912D0 (en) | 2010-10-07 | 2010-11-24 | Astrazeneca Ab | Novel combination |
| GB201021992D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | Compound |
| GB201021979D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | New compound |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1468012A (en) * | 1973-08-09 | 1977-03-23 | Beecham Group Ltd | 2-amino-3-carboxy-thiophene derivatives |
| DE3529247A1 (de) | 1985-05-17 | 1986-11-20 | Bayer Ag, 5090 Leverkusen | Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung |
| GB2195634B (en) | 1986-10-01 | 1990-08-15 | Roussel Lab Ltd | Thiophene derivatives |
| US5258357A (en) * | 1989-10-07 | 1993-11-02 | Basf Aktiengesellschaft | Carboxamides, their preparation and their use as herbicides |
| US5378703A (en) * | 1990-04-09 | 1995-01-03 | Alcon Laboratories, Inc. | Sulfonamides useful as carbonic anhydrase inhibitors |
| US5571810A (en) * | 1990-06-11 | 1996-11-05 | Fujisawa Pharmaceutical Co., Ltd. | Thiophene derivatives |
| US5514801A (en) * | 1992-12-29 | 1996-05-07 | Monsanto Company | Cyclic sulfone containing retroviral protease inhibitors |
| US6417202B1 (en) | 1996-07-11 | 2002-07-09 | Pfizer Inc. | Pyridylpyrrole compounds useful as interleukin-and TNF antagonists |
| PT853083E (pt) | 1997-01-06 | 2001-12-28 | Pfizer | Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica |
| US6809088B2 (en) * | 1997-03-24 | 2004-10-26 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them |
| AU6959898A (en) * | 1997-04-11 | 1998-11-11 | David J. Grainger | Compounds and therapies for the prevention of vascular and non-vascular pathol ogies |
| US6037340A (en) | 1997-05-28 | 2000-03-14 | Cadus Pharmaceutical Corporation | Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds |
| DE19744026A1 (de) | 1997-10-06 | 1999-04-08 | Hoechst Marion Roussel De Gmbh | Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
| WO1999046244A1 (en) | 1998-03-12 | 1999-09-16 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (ptpases) |
| WO2000002851A1 (en) * | 1998-07-08 | 2000-01-20 | Aventis Pharma Deutschland Gmbh | Sulfur substituted sulfonylaminocarboxylic acid n-arylamides, their preparation, their use and pharmaceutical preparations comprising them |
| HN2000000051A (es) * | 1999-05-19 | 2001-02-02 | Pfizer Prod Inc | Derivados heterociclicos utiles como agentes anticancerosos |
| GB0003154D0 (en) * | 2000-02-12 | 2000-04-05 | Astrazeneca Uk Ltd | Novel compounds |
| JP5074653B2 (ja) * | 2000-03-29 | 2012-11-14 | サイクラセル リミテッド | 2−置換4−ヘテロアリール−ピリミジンおよび増殖性障害におけるその使用 |
| US6414013B1 (en) * | 2000-06-19 | 2002-07-02 | Pharmacia & Upjohn S.P.A. | Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention |
| AU2002211663A1 (en) | 2000-10-12 | 2002-04-22 | Smith Kline Beecham Corporation | Nf-$g(k)b inhibitors |
| US7122544B2 (en) * | 2000-12-06 | 2006-10-17 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto |
| US20050238911A1 (en) | 2001-03-16 | 2005-10-27 | Sturley David K | Non-powered luminous panels and devices and method of manufacture |
| US6713638B2 (en) * | 2001-05-18 | 2004-03-30 | Joel M. Linden | 2-amino-3-aroyl-4,5 alkylthiophenes: agonist allosteric enhancers at human A1 adenosine receptors |
| PL395097A1 (pl) * | 2001-06-11 | 2011-10-10 | Vertex Pharmaceuticals (Canada) Incorporated | Sposób wytwarzania związku o wzorze A stanowiącego pochodną tiofenu |
| SE0102616D0 (sv) * | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
| SE0102617D0 (sv) | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
| WO2003029241A1 (en) | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | Chk1 kinase inhibitors |
| JP2005506334A (ja) * | 2001-10-04 | 2005-03-03 | スミスクライン・ビーチャム・コーポレイション | NF−κB阻害剤 |
| WO2003028731A1 (en) | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | Chk1 kinase inhibitors |
| TWI281916B (en) * | 2001-10-25 | 2007-06-01 | Lilly Co Eli | Antitumor compounds and methods |
| US6835745B2 (en) * | 2002-01-15 | 2004-12-28 | Wyeth | Phenyl substituted thiophenes as estrogenic agents |
| US7196106B2 (en) * | 2002-11-05 | 2007-03-27 | Merck & Co., Inc | Cyanothiophene derivatives, compositions containing such compounds and methods of use |
| SE0300092D0 (sv) * | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
| SE0300091D0 (sv) | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
-
2003
- 2003-01-15 SE SE0300091A patent/SE0300091D0/xx unknown
-
2004
- 2004-01-13 KR KR1020057013033A patent/KR20050098248A/ko not_active Ceased
- 2004-01-13 MX MXPA05007340A patent/MXPA05007340A/es active IP Right Grant
- 2004-01-13 CN CNB2004800023046A patent/CN1315820C/zh not_active Expired - Fee Related
- 2004-01-13 WO PCT/GB2004/000106 patent/WO2004063185A1/en not_active Ceased
- 2004-01-13 AT AT04701632T patent/ATE374762T1/de active
- 2004-01-13 NZ NZ541219A patent/NZ541219A/en not_active IP Right Cessation
- 2004-01-13 US US10/542,044 patent/US7553868B2/en not_active Expired - Fee Related
- 2004-01-13 ES ES04701632T patent/ES2293206T3/es not_active Expired - Lifetime
- 2004-01-13 JP JP2006500206A patent/JP4568714B2/ja not_active Expired - Fee Related
- 2004-01-13 EP EP04701632A patent/EP1583756B9/en not_active Expired - Lifetime
- 2004-01-13 PT PT04701632T patent/PT1583756E/pt unknown
- 2004-01-13 DE DE602004009283T patent/DE602004009283T2/de not_active Expired - Lifetime
- 2004-01-13 CA CA002512336A patent/CA2512336A1/en not_active Abandoned
- 2004-01-13 BR BR0406774-6A patent/BRPI0406774A/pt not_active IP Right Cessation
- 2004-01-13 DK DK04701632T patent/DK1583756T3/da active
-
2005
- 2005-06-27 ZA ZA200505190A patent/ZA200505190B/en unknown
- 2005-06-29 IL IL169478A patent/IL169478A/en not_active IP Right Cessation
- 2005-08-12 NO NO20053810A patent/NO20053810L/no not_active Application Discontinuation
-
2007
- 2007-11-29 CY CY20071101528T patent/CY1107817T1/el unknown
-
2009
- 2009-05-04 US US12/435,054 patent/US20090215829A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT1583756E (pt) | 2007-12-03 |
| KR20050098248A (ko) | 2005-10-11 |
| IL169478A0 (en) | 2009-02-11 |
| CA2512336A1 (en) | 2004-07-29 |
| EP1583756B1 (en) | 2007-10-03 |
| CN1738812A (zh) | 2006-02-22 |
| US7553868B2 (en) | 2009-06-30 |
| WO2004063185A1 (en) | 2004-07-29 |
| US20060111431A1 (en) | 2006-05-25 |
| WO2004063185A8 (en) | 2004-09-23 |
| MXPA05007340A (es) | 2005-09-30 |
| US20090215829A1 (en) | 2009-08-27 |
| BRPI0406774A (pt) | 2005-12-27 |
| ES2293206T3 (es) | 2008-03-16 |
| CN1315820C (zh) | 2007-05-16 |
| JP2006515355A (ja) | 2006-05-25 |
| EP1583756A1 (en) | 2005-10-12 |
| NO20053810L (no) | 2005-10-12 |
| ATE374762T1 (de) | 2007-10-15 |
| IL169478A (en) | 2010-02-17 |
| CY1107817T1 (el) | 2013-06-19 |
| ZA200505190B (en) | 2006-04-26 |
| EP1583756B9 (en) | 2008-01-09 |
| DE602004009283T2 (de) | 2008-07-10 |
| NZ541219A (en) | 2008-03-28 |
| DK1583756T3 (da) | 2007-12-17 |
| AU2004203967A1 (en) | 2004-07-29 |
| HK1082250A1 (en) | 2006-06-02 |
| NO20053810D0 (no) | 2005-08-12 |
| JP4568714B2 (ja) | 2010-10-27 |
| DE602004009283D1 (de) | 2007-11-15 |
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