DK1428530T3 - Tetrapeptidderivatkrystaller - Google Patents
TetrapeptidderivatkrystallerInfo
- Publication number
- DK1428530T3 DK1428530T3 DK02799487T DK02799487T DK1428530T3 DK 1428530 T3 DK1428530 T3 DK 1428530T3 DK 02799487 T DK02799487 T DK 02799487T DK 02799487 T DK02799487 T DK 02799487T DK 1428530 T3 DK1428530 T3 DK 1428530T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivative crystals
- tetrapeptide derivative
- methoxy
- methyl
- crystals
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001286674 | 2001-09-20 | ||
| PCT/JP2002/009628 WO2003026645A1 (en) | 2001-09-20 | 2002-09-19 | Tetrapeptide derivative crystals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1428530T3 true DK1428530T3 (da) | 2008-12-01 |
Family
ID=19109609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02799487T DK1428530T3 (da) | 2001-09-20 | 2002-09-19 | Tetrapeptidderivatkrystaller |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7008928B2 (ja) |
| EP (1) | EP1428530B1 (ja) |
| JP (1) | JP4060794B2 (ja) |
| KR (1) | KR100901096B1 (ja) |
| CN (2) | CN1834088A (ja) |
| AT (1) | ATE405578T1 (ja) |
| AU (1) | AU2002362579B2 (ja) |
| CA (1) | CA2460956C (ja) |
| DE (1) | DE60228459D1 (ja) |
| DK (1) | DK1428530T3 (ja) |
| ES (1) | ES2309233T3 (ja) |
| WO (1) | WO2003026645A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101291683B (zh) * | 2004-11-24 | 2011-08-17 | 纽普罗研究有限公司 | 治疗疾病的方法和组合物 |
| CA2647835A1 (en) * | 2006-03-28 | 2007-10-04 | Neopro Labs, Llc | Methods and compositions for treating conditions |
| US8217141B2 (en) * | 2007-05-17 | 2012-07-10 | Neopro Labs, Llc | Crystalline and amorphous forms of peptide |
| WO2009012472A2 (en) * | 2007-07-18 | 2009-01-22 | Neopro Labs, Llc | Methods and compositions for treating conditions |
| ES2883023T3 (es) * | 2014-05-28 | 2021-12-03 | Agensys Inc | Derivados de péptidos de dolaproína-dolaisoleuina citotóxicos para el tratamiento del cáncer |
| US10435435B2 (en) * | 2015-07-24 | 2019-10-08 | The Arizona Board Of Regents On Behalf Of Arizona State University | Quinstatin compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4978744A (en) * | 1989-01-27 | 1990-12-18 | Arizona Board Of Regents | Synthesis of dolastatin 10 |
| EP0598129B1 (en) | 1991-08-09 | 2000-03-22 | Teikoku Hormone Mfg. Co., Ltd. | Novel tetrapeptide derivative |
| US6034065A (en) * | 1992-12-03 | 2000-03-07 | Arizona Board Of Regents | Elucidation and synthesis of antineoplastic tetrapeptide phenethylamides of dolastatin 10 |
-
2002
- 2002-09-19 CN CNA2006100043182A patent/CN1834088A/zh active Pending
- 2002-09-19 ES ES02799487T patent/ES2309233T3/es not_active Expired - Lifetime
- 2002-09-19 AT AT02799487T patent/ATE405578T1/de active
- 2002-09-19 JP JP2003530282A patent/JP4060794B2/ja not_active Expired - Fee Related
- 2002-09-19 DE DE60228459T patent/DE60228459D1/de not_active Expired - Lifetime
- 2002-09-19 CN CNB028185250A patent/CN1309413C/zh not_active Expired - Fee Related
- 2002-09-19 EP EP02799487A patent/EP1428530B1/en not_active Expired - Lifetime
- 2002-09-19 KR KR1020047002898A patent/KR100901096B1/ko not_active Expired - Fee Related
- 2002-09-19 WO PCT/JP2002/009628 patent/WO2003026645A1/ja not_active Ceased
- 2002-09-19 CA CA2460956A patent/CA2460956C/en not_active Expired - Fee Related
- 2002-09-19 DK DK02799487T patent/DK1428530T3/da active
- 2002-09-19 US US10/490,340 patent/US7008928B2/en not_active Expired - Lifetime
- 2002-09-19 AU AU2002362579A patent/AU2002362579B2/en not_active Ceased
-
2005
- 2005-07-14 US US11/180,582 patent/US7385029B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7385029B2 (en) | 2008-06-10 |
| US20050267041A1 (en) | 2005-12-01 |
| US7008928B2 (en) | 2006-03-07 |
| KR20040036922A (ko) | 2004-05-03 |
| CN1556701A (zh) | 2004-12-22 |
| CN1834088A (zh) | 2006-09-20 |
| EP1428530B1 (en) | 2008-08-20 |
| CA2460956C (en) | 2010-12-21 |
| AU2002362579B2 (en) | 2007-09-06 |
| ATE405578T1 (de) | 2008-09-15 |
| CA2460956A1 (en) | 2003-04-03 |
| US20040254343A1 (en) | 2004-12-16 |
| WO2003026645A1 (en) | 2003-04-03 |
| EP1428530A8 (en) | 2005-01-26 |
| WO2003026645A8 (en) | 2004-09-30 |
| CN1309413C (zh) | 2007-04-11 |
| JPWO2003026645A1 (ja) | 2005-01-06 |
| EP1428530A1 (en) | 2004-06-16 |
| DE60228459D1 (de) | 2008-10-02 |
| JP4060794B2 (ja) | 2008-03-12 |
| ES2309233T3 (es) | 2008-12-16 |
| KR100901096B1 (ko) | 2009-06-08 |
| EP1428530A4 (en) | 2005-03-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA200300566A1 (ru) | Применение cci-779 в качестве противоопухолевого средства | |
| EP1477482A4 (en) | NEW PHENYLALANINE DERIVATIVE | |
| CY1109718T1 (el) | Παραγωγο 2-οξο-1-πυρρολιδινης και οι φαρμακευτικες του χρησεις | |
| DK0639577T3 (da) | Phosphonooxymethyl- eller methylthiomethylestere af taxanderivater som antitumormidler | |
| PA8477801A1 (es) | (3s) tetrahidro-3-furanil (1s,2r)-3-[[4-aminofenil) sulfonil)] (isobutil) amino]-1-bencil-2-(fosfonooxi) propilcarbamato de calcio | |
| EA200100411A1 (ru) | Замещенные 3-цианохинолины в качестве ингибиторов протеинтирозинкиназ | |
| DE60204452D1 (de) | Pyrazolo[1,5]pyridinderivate | |
| ATE210988T1 (de) | Zytotoxischer aminozucker und verwandte zuckerderivate von indolopyrrolocarbazolen | |
| DK1097173T3 (da) | Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler | |
| BR0112375A (pt) | Métodos de sìntese para aplidina e novos derivados antitumorais, métodos para fabrica-los e usá-los. | |
| UY27287A1 (es) | Sal citrato de 5,8,14-triazatetraciclo[10.3.1.0 2,11.0 4,9] hexadeca-2(11),3,5,7,9-pentaeno y composiciones farmaceuticas de la misma | |
| NO20043016L (no) | 6-aminomorfinan-derivater, fremgangsmate for fremstilling og anvendelse derav | |
| BR9813817A (pt) | Análogos de hemiasterlina | |
| WO2002053519A3 (en) | Hydrophobic polyamine analogs and methods for their use | |
| ECSP034598A (es) | Compuesto lactamico | |
| ATE405578T1 (de) | Tetrapeptid-derivat-kristalle | |
| DK1383742T3 (da) | Syntese og fremgangsmåder til anvendelse af tetrahydroindolonanaloge og derivater | |
| NO20054535L (no) | Bifunksjonelle heterocykliske forbindelser og fremgangsmater for fremstilling og anvendelse av samme | |
| DE69917005D1 (de) | Substituierte pyrrolobenzimidazolderivate zur entzündungshemmung | |
| DE69936052D1 (de) | N1 modifizierte glycopeptide | |
| NO995676D0 (no) | Isoftalamid derivat som gul polymorf | |
| DE60220800D1 (de) | Chirales dinapsolin | |
| ATE236865T1 (de) | 6-substituierte 3-methyloct-6-enole | |
| ATE298742T1 (de) | Zykloalkenylsulfonamidderivate | |
| DE60204269D1 (de) | Zutat für Säuglingsmilchnahrung |