|
GB9818731D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
|
ATE240334T1
(de)
|
1998-08-27 |
2003-05-15 |
Spirogen Ltd |
Pyrrolobenzodiazepine
|
|
GB9818732D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
|
GB0226593D0
(en)
*
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
|
DE60326060D1
(de)
*
|
2003-03-31 |
2009-03-19 |
Council Scient Ind Res |
Nichtvernetzende pyrroloä2,1-cüä1,4übenzodiazepine als potentielle antitumor-agentien und ihre herstellung
|
|
GB0321295D0
(en)
*
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
|
US7511032B2
(en)
|
2003-10-22 |
2009-03-31 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
|
|
GB0416511D0
(en)
*
|
2003-10-22 |
2004-08-25 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
WO2005040172A1
(fr)
*
|
2003-10-29 |
2005-05-06 |
Kyowa Hakko Kogyo Co., Ltd. |
Dérivé proline tricyclique
|
|
JP4718328B2
(ja)
*
|
2003-12-31 |
2011-07-06 |
カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ |
Ｃ８連結したピロロ［２，１−ｃ］［１，４］ベンゾジアゼピン−アクリドン／アクリジン・ハイブリッド
|
|
JP4520411B2
(ja)
*
|
2003-12-31 |
2010-08-04 |
カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ |
ピロロ［２，１−ｃ］［１，４］ベンゾジアゼピン・ハイブリッドの調製方法
|
|
GB0404577D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
AU2005219626B2
(en)
|
2004-03-01 |
2010-11-18 |
Medimmune Limited |
11-hydroxy-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one derivatives as key intermediates for the preparation of C2 substituted pyrrolobenzodiazepines
|
|
GB0404574D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
|
GB0404578D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
JP5166861B2
(ja)
*
|
2004-03-09 |
2013-03-21 |
スピロゲン リミティッド |
ピロロベンゾジアゼピン
|
|
US7056913B2
(en)
|
2004-03-30 |
2006-06-06 |
Council Of Scientific And Industrial Research |
C8—linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids
|
|
US6951853B1
(en)
|
2004-03-30 |
2005-10-04 |
Council Of Scientific And Industrial Research |
Process for preparing pyrrolo[2, 1-c] [1,4] benzodiazepine hybrids
|
|
FR2869231B1
(fr)
*
|
2004-04-27 |
2008-03-14 |
Sod Conseils Rech Applic |
Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
|
|
GB0410725D0
(en)
*
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
|
DE602006011300D1
(de)
*
|
2005-04-21 |
2010-02-04 |
Spirogen Ltd |
Pyrrolobenzodiazepine
|
|
GB0508084D0
(en)
*
|
2005-04-21 |
2005-06-01 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
WO2007039752A1
(fr)
*
|
2005-10-05 |
2007-04-12 |
Spirogen Limited |
Derives d'alkyle 4-[4-(5-oxo-2, 3, 5, 11a-tetrahydro-5h-pyrrolo [2, 1-c] [1, 4] benzodiazepine-8-yloxy) -butyrylamino]-1h-pyrrole-2-carboxylate et composes associes destines au traitement d'une maladie hyperplasique
|
|
PT1813614E
(pt)
*
|
2006-01-25 |
2012-01-09 |
Sanofi Sa |
Agentes citotóxicos compreendendo novos derivados de tomaimicina
|
|
DE102006013678A1
(de)
*
|
2006-03-24 |
2007-09-27 |
Bayerische Motoren Werke Ag |
Gleit- oder Schmiermittel und Verfahren zum Aufziehen eines Fahrzeugreifens auf eine Felge
|
|
EA020324B1
(ru)
|
2006-07-18 |
2014-10-30 |
Санофи-Авентис |
АНТИТЕЛА К РЕЦЕПТОРУ ЭФРИНА EphA2 И ИХ ПРИМЕНЕНИЕ
|
|
GB0619325D0
(en)
|
2006-09-30 |
2006-11-08 |
Univ Strathclyde |
New compounds
|
|
EP1914242A1
(fr)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Nouveau anticorps Anti-CD38 pour le traitement du cancer
|
|
DK2019104T3
(da)
|
2007-07-19 |
2013-12-16 |
Sanofi Sa |
Cytotoksiske midler, der omfatter nye tomaymycinderivater, og terapeutisk anvendelse deraf
|
|
CN104524592B
(zh)
|
2008-04-30 |
2018-06-05 |
伊缪诺金公司 |
交联剂和它们的用途
|
|
GB0813432D0
(en)
*
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819097D0
(en)
*
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
CN102365021B
(zh)
*
|
2009-02-05 |
2015-07-15 |
伊缪诺金公司 |
新型苯并二氮杂*衍生物
|
|
AU2015224492B2
(en)
*
|
2009-02-05 |
2017-04-20 |
Immunogen, Inc. |
Novel benzodiazepine derivatives
|
|
KR101947176B1
(ko)
|
2009-06-03 |
2019-02-12 |
이뮤노젠 아이엔씨 |
접합 방법
|
|
FR2949469A1
(fr)
*
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
|
UY32914A
(es)
|
2009-10-02 |
2011-04-29 |
Sanofi Aventis |
Anticuerpos que se usan específicamente al receptor epha2
|
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
|
MX2012011900A
(es)
|
2010-04-15 |
2013-03-21 |
Seattle Genetics Inc |
Conjugados de pirrolobenzodiazepina diana.
|
|
HRP20130953T1
(hr)
|
2010-04-15 |
2013-11-22 |
Spirogen Sàrl |
Pirolobenzodiazepini i njihovi konjugati
|
|
US8697688B2
(en)
|
2010-04-15 |
2014-04-15 |
Seattle Genetics Inc. |
Pyrrolobenzodiazepines used to treat proliferative diseases
|
|
FR2963007B1
(fr)
|
2010-07-26 |
2013-04-05 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application therapeutique
|
|
SMT201900181T1
(it)
|
2011-02-15 |
2019-05-10 |
Immunogen Inc |
Metodi di preparazione di coniugati
|
|
FR2972006B1
(fr)
|
2011-02-24 |
2016-03-25 |
Centre Nat Rech Scient |
Nouveaux fragments d'il-33 superactifs et leurs utilisations
|
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
|
EP2751120B1
(fr)
|
2011-09-20 |
2018-08-22 |
MedImmune Limited |
Pyrrolobenzodiazépines comme composés dimères de pbd asymétriques pour inclusion dans des conjugués cibles
|
|
CN103998450B
(zh)
*
|
2011-10-14 |
2017-03-08 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓
|
|
BR112014009070B1
(pt)
|
2011-10-14 |
2021-11-23 |
Medimmune Limited |
Método de síntese e intermediários úteis na preparação de pirrolobenzo-diazepinas
|
|
CA2850373C
(fr)
|
2011-10-14 |
2019-07-16 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines et conjugues cibles
|
|
CN110183470A
(zh)
|
2011-10-14 |
2019-08-30 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓
|
|
PL2750713T3
(pl)
|
2011-10-14 |
2016-03-31 |
Medimmune Ltd |
Pirolobenzodiazepiny i ich koniugaty
|
|
US9387259B2
(en)
*
|
2011-10-14 |
2016-07-12 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines and targeted conjugates
|
|
SMT201700467T1
(it)
|
2012-02-24 |
2017-11-15 |
Abbvie Stemcentrx Llc |
Modulatori di dll3 e metodi di uso
|
|
SG11201405130UA
(en)
|
2012-02-24 |
2014-11-27 |
Stemcentrx Inc |
Anti sez6 antibodies and methods of use
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
JP6125614B2
(ja)
|
2012-04-30 |
2017-05-10 |
ユーシーエル ビジネス ピーエルシー |
ピロロベンゾジアゼピン
|
|
NZ701290A
(en)
|
2012-04-30 |
2016-08-26 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
RU2014148162A
(ru)
|
2012-05-01 |
2016-06-20 |
Дженентек, Инк. |
Анти-pmel17 антитела и их иммуноконъюгаты
|
|
HK1209043A1
(en)
|
2012-07-09 |
2016-03-24 |
基因泰克公司 |
Immunoconjugates comprising anti-cd22 antibodies
|
|
US20140030280A1
(en)
|
2012-07-09 |
2014-01-30 |
Genentech, Inc. |
Anti-cd79b antibodies and immunoconjugates
|
|
CN104717979A
(zh)
|
2012-08-02 |
2015-06-17 |
基因泰克公司 |
抗etbr抗体和免疫偶联物
|
|
WO2014031566A1
(fr)
|
2012-08-22 |
2014-02-27 |
Immunogen, Inc. |
Dérivés de benzodiazépine cytotoxique
|
|
MX364329B
(es)
|
2012-10-12 |
2019-04-23 |
Medimmune Ltd |
Conjugados del anticuerpo pirrolobenzodiazepina.
|
|
WO2014057120A1
(fr)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Conjugués anticorps - pyrrolobenzodiazépine
|
|
CN110256469B
(zh)
|
2012-10-12 |
2022-05-17 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓及其结合物
|
|
DK2906253T3
(en)
|
2012-10-12 |
2018-10-22 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine anti-PSMA antibody conjugates
|
|
DK2839860T3
(da)
|
2012-10-12 |
2019-06-17 |
Medimmune Ltd |
Pyrrolobenzodiazepiner og konjugater deraf
|
|
ES2680153T3
(es)
|
2012-10-12 |
2018-09-04 |
Adc Therapeutics Sa |
Conjugados de anticuerpos anti-PSMA-pirrolobenzodiazepinas
|
|
EP2906249B1
(fr)
|
2012-10-12 |
2018-06-27 |
MedImmune Limited |
Synthèse et intermédiaires de dérivés de pyrrolobenzodiazépine pour conjugaison
|
|
WO2014057119A1
(fr)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Conjugués anticorps - pyrrolobenzodiazépine
|
|
PL2906251T3
(pl)
|
2012-10-12 |
2018-02-28 |
Adc Therapeutics Sa |
Koniugaty pirolobenzodiazepina-przeciwciało anty-CD22
|
|
JP6133431B2
(ja)
|
2012-11-24 |
2017-05-24 |
ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ．Ｈａｎｇｚｈｏｕ Ｄａｃ Ｂｉｏｔｅｃｈ Ｃｏ．，Ｌｔｄ． |
親水性連結体及び薬物分子と細胞結合分子との共役反応における親水性連結体の使用
|
|
CN105246894A
(zh)
|
2012-12-21 |
2016-01-13 |
斯皮罗根有限公司 |
用于治疗增殖性和自身免疫疾病的非对称吡咯并苯并二氮杂卓二聚物
|
|
EA031585B1
(ru)
|
2012-12-21 |
2019-01-31 |
Медимьюн Лимитед |
Пирролобензодиазепины и их конъюгаты
|
|
TR201908761T4
(tr)
|
2013-02-22 |
2019-07-22 |
Abbvie Stemcentrx Llc |
Antidll3-antikor-pbd konjugatları ve kullanımları.
|
|
ES2687439T3
(es)
|
2013-03-13 |
2018-10-25 |
Medimmune Limited |
Pirrolobenzodiazepinas y conjugados de las mismas
|
|
CN105142674B
(zh)
|
2013-03-13 |
2018-11-13 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓和其结合物
|
|
NZ710745A
(en)
|
2013-03-13 |
2019-03-29 |
Genentech Inc |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
AU2014244424A1
(en)
|
2013-03-14 |
2015-08-27 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
BR112016002829A2
(pt)
|
2013-08-12 |
2017-09-19 |
Genentech Inc |
Composto e processo para preparar o composto de conjugado anticorpo-¿droga, composição farmacêutica, método de tratamento do câncer, kit para o tratamento do câncer, intermediário ligante¿-droga, porção e composto de porção droga de dímero cbi
|
|
KR20160046914A
(ko)
|
2013-08-28 |
2016-04-29 |
스템센트알엑스 인코포레이티드 |
신규한 ｓｅｚ6 조절물질 및 사용방법
|
|
MX377339B
(es)
|
2013-08-28 |
2025-03-06 |
Abbvie Stemcentrx Llc |
Metodos de conjugacion de anticuerpos especificos de sitio y composiciones.
|
|
KR20160055253A
(ko)
|
2013-09-12 |
2016-05-17 |
할로자임, 아이엔씨 |
변형된 항-상피세포 성장인자 수용체 항체 및 이의 사용 방법
|
|
KR20160055252A
(ko)
|
2013-09-17 |
2016-05-17 |
제넨테크, 인크. |
항-lgr5 항체의 사용 방법
|
|
US9956299B2
(en)
|
2013-10-11 |
2018-05-01 |
Medimmune Limited |
Pyrrolobenzodiazepine—antibody conjugates
|
|
US9950078B2
(en)
|
2013-10-11 |
2018-04-24 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US10010624B2
(en)
|
2013-10-11 |
2018-07-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US10053511B2
(en)
|
2013-11-06 |
2018-08-21 |
Abbvie Stemcentrx Llc |
Anti-claudin antibodies and methods of use
|
|
CN105744935B
(zh)
|
2013-11-27 |
2022-09-30 |
雷德伍德生物科技股份有限公司 |
肼基-吡咯并化合物及用于生成缀合物的方法
|
|
PE20160993A1
(es)
|
2013-12-12 |
2016-10-14 |
Abbvie Stemcentrx Llc |
Nuevos anticuerpos anti-dpep3 y metodos de uso
|
|
EP3461845B1
(fr)
|
2013-12-13 |
2020-09-16 |
Genentech, Inc. |
Anticorps et immunoconjugués anti-cd33
|
|
JP6980384B2
(ja)
|
2013-12-16 |
2021-12-15 |
ジェネンテック， インコーポレイテッド |
１−（クロロメチル）−２，３−ジヒドロ−１ｈ−ベンゾ［ｅ］インドール二量体抗体−薬物コンジュゲート化合物、並びに使用及び処置の方法
|
|
EP3107576A4
(fr)
|
2014-02-21 |
2017-09-06 |
Abbvie Stemcentrx LLC |
Anticorps anti-dll3 et conjugués de médicaments destinés à être utilisés dans un mélanome
|
|
US10464955B2
(en)
|
2014-02-28 |
2019-11-05 |
Hangzhou Dac Biotech Co., Ltd. |
Charged linkers and their uses for conjugation
|
|
GB201407816D0
(en)
|
2014-05-02 |
2014-06-18 |
King S College London |
Pyrrolobenzodiazepine Compounds
|
|
EP3145952A2
(fr)
|
2014-05-22 |
2017-03-29 |
Genentech, Inc. |
Anti-gpc3 anticors et immunoconjugates
|
|
RU2764074C2
(ru)
|
2014-08-28 |
2022-01-13 |
Байоатла, Ллк |
Условно активные химерные антигенные рецепторы для модифицированных т-клеток
|
|
MX2017002758A
(es)
|
2014-09-03 |
2017-10-20 |
Immunogen Inc |
Derivados de benzodiazepina citotoxicos.
|
|
US9381256B2
(en)
|
2014-09-03 |
2016-07-05 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
TW201617368A
(zh)
|
2014-09-05 |
2016-05-16 |
史坦森特瑞斯公司 |
新穎抗ｍｆｉ２抗體及使用方法
|
|
CN106687141A
(zh)
|
2014-09-10 |
2017-05-17 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓及其缀合物
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
KR102508173B1
(ko)
|
2014-09-12 |
2023-03-10 |
제넨테크, 인크. |
항-her2 항체 및 면역콘주게이트
|
|
US9751946B2
(en)
|
2014-09-12 |
2017-09-05 |
Genentech, Inc. |
Anti-CLL-1 antibodies and immunoconjugates
|
|
EP3191518B1
(fr)
|
2014-09-12 |
2020-01-15 |
Genentech, Inc. |
Anticorps anti-b7-h4 et immunoconjugués
|
|
EP3388449A3
(fr)
|
2014-09-12 |
2018-10-24 |
F. Hoffmann-La Roche AG |
Anticorps et conjugués modifies génetiquement avec de la cystéine
|
|
HK1243629A1
(zh)
|
2014-09-17 |
2018-07-20 |
基因泰克公司 |
包含抗her2抗体和吡咯并苯并二氮杂䓬的免疫缀合物
|
|
CN107148285B
(zh)
|
2014-11-25 |
2022-01-04 |
Adc治疗股份有限公司 |
吡咯并苯并二氮杂䓬-抗体缀合物
|
|
TN2017000246A1
(en)
|
2014-12-11 |
2018-10-19 |
Pf Medicament |
Anti-c10orf54 antibodies and uses thereof
|
|
MX2017009145A
(es)
|
2015-01-14 |
2017-11-22 |
Bristol Myers Squibb Co |
Dimeros de benzodiazepina, conjugados de estos, y sus metodos de preparacion y uso.
|
|
BR112017014937A2
(pt)
|
2015-01-14 |
2018-03-13 |
Bristol-Myers Squibb Company |
dímeros de benzodiazepina ligados em ponte a heteroarileno, conjugados dos mesmos, e métodos de preparação e uso
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
GB201510010D0
(en)
|
2015-06-09 |
2015-07-22 |
King S College London |
PDD and BPD compounds
|
|
AU2015242210A1
(en)
|
2015-06-15 |
2017-12-07 |
Hangzhou Dac Biotech Co., Ltd |
Hydrophilic linkers for conjugation
|
|
CN108391434A
(zh)
|
2015-06-23 |
2018-08-10 |
百时美施贵宝公司 |
大环苯并二氮杂*二聚体、其缀合物、制备和用途
|
|
JP6759326B2
(ja)
|
2015-07-12 |
2020-09-23 |
ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ．Ｈａｎｇｚｈｏｕ Ｄａｃ Ｂｉｏｔｅｃｈ Ｃｏ．，Ｌｔｄ． |
細胞結合分子の共役のための架橋連結体
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
EP3325483B1
(fr)
|
2015-07-21 |
2019-10-02 |
ImmunoGen, Inc. |
Procédés de préparation de dérivés de benzodiazépine cytotoxiques
|
|
US20180339985A1
(en)
|
2015-08-21 |
2018-11-29 |
Femtogenix Limited |
Pdd compounds
|
|
GB201514928D0
(en)
|
2015-08-21 |
2015-10-07 |
King S College London |
PDD compounds
|
|
EP4477269A3
(fr)
|
2015-09-20 |
2025-03-19 |
The United States of America, as Represented By the Secretary, Department of Health and Human Services |
Anticorps monoclonaux spécifiques du récepteur de facteur de croissance des fibroblastes 4 (fgfr4) et leurs procédés d'utilisation
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
CN108463226B
(zh)
|
2015-11-09 |
2022-04-15 |
R.P.谢勒技术有限责任公司 |
抗cd22抗体-美登木素缀合物及其使用方法
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
WO2017161206A1
(fr)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugués contenant des anticorps à activité conditionnelle ou des fragments de liaison à un antigène associés, et procédés d'utilisation
|
|
MA45328A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Compositions acide nucléique-polypeptide et utilisations de celles-ci
|
|
CN109563164A
(zh)
|
2016-04-15 |
2019-04-02 |
生物蛋白有限公司 |
抗axl抗体、抗体片段和它们的免疫缀合物以及其用途
|
|
US10934359B2
(en)
|
2016-04-21 |
2021-03-02 |
Abbvie Stemcentrx Llc |
Anti-BMPR1B antibodies and methods of use
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
WO2017196847A1
(fr)
|
2016-05-10 |
2017-11-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps anti-nouveau récepteur variable d'antigène (vnar) et conjugués d'anticorps ciblant des antigènes tumoraux et viraux
|
|
TW201808336A
(zh)
|
2016-05-11 |
2018-03-16 |
賽諾菲公司 |
用抗ｍｕｃ１類美登素免疫綴合物抗體治療腫瘤的治療方案
|
|
TWI844509B
(zh)
|
2016-05-13 |
2024-06-11 |
美商拜奧亞特拉公司 |
抗-ror2抗體、抗體片段、其免疫結合物及其用途
|
|
CN109313200B
(zh)
|
2016-05-27 |
2022-10-04 |
豪夫迈·罗氏有限公司 |
用于表征位点特异性抗体-药物缀合物的生物分析性方法
|
|
WO2017214182A1
(fr)
|
2016-06-07 |
2017-12-14 |
The United States Of America. As Represented By The Secretary, Department Of Health & Human Services |
Anticorps entièrement humain ciblant pdi pour l'immunothérapie anticancéreuse
|
|
EP3494135A1
(fr)
|
2016-08-02 |
2019-06-12 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Anticorps monoclonaux ciblant le glypican-2 (gpc2) et leur utilisation
|
|
JP2019530434A
(ja)
|
2016-08-05 |
2019-10-24 |
ジェネンテック， インコーポレイテッド |
アゴニスト活性を有する多価及び多重エピトープ抗体ならびに使用方法
|
|
CN109689111B
(zh)
|
2016-08-11 |
2024-04-05 |
基因泰克公司 |
吡咯并苯并二氮杂䓬前药及其抗体缀合物
|
|
CN109862919A
(zh)
|
2016-10-11 |
2019-06-07 |
免疫医疗有限公司 |
抗体-药物缀合物联合免疫介导的治疗剂
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
CN110099682B
(zh)
|
2016-11-14 |
2023-03-31 |
杭州多禧生物科技有限公司 |
偶联连接体，含有此连接体的细胞结合分子-药物偶联物及其制备和应用
|
|
WO2018091724A1
(fr)
|
2016-11-21 |
2018-05-24 |
Cureab Gmbh |
Anticorps anti-gp73 et immunoconjugués
|
|
FR3059550B1
(fr)
|
2016-12-01 |
2020-01-03 |
Universite De Rouen Normandie |
Traitement des troubles causes par l'alcoolisation foetale (tcaf)
|
|
US11236171B2
(en)
|
2016-12-21 |
2022-02-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies specific for FLT3 and uses thereof
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
BR112019016373B1
(pt)
|
2017-02-08 |
2022-01-25 |
Medimmune Limited |
Conjugado anticorpo-fármaco que se liga ao axl, composição e composição farmacêutica que compreende o mesmo e uso terapêutico do dito conjugado
|
|
ES2926144T3
(es)
|
2017-04-18 |
2022-10-24 |
Medimmune Ltd |
Conjugados de pirrolobenzodiazepina
|
|
JP7408396B2
(ja)
|
2017-04-20 |
2024-01-05 |
アーデーセー セラピューティクス ソシエテ アノニム |
併用療法
|
|
TW201839001A
(zh)
|
2017-04-20 |
2018-11-01 |
美商伊繆諾金公司 |
細胞毒性苯并二氮平衍生物及其綴合物
|
|
US11389480B2
(en)
|
2017-05-19 |
2022-07-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibody targeting TNFR2 for cancer immunotherapy
|
|
PL3638373T3
(pl)
|
2017-06-14 |
2025-04-14 |
Adc Therapeutics Sa |
Schematy dawkowania dla podawania ADC anty-CD19
|
|
CA3066953A1
(fr)
|
2017-06-30 |
2019-01-03 |
Lentigen Technology, Inc. |
Anticorps monoclonaux humains specifiques de cd33 et leurs procedes d'utilisation
|
|
WO2019005208A1
(fr)
|
2017-06-30 |
2019-01-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps de la mésothéline humaine et utilisations dans une thérapie anticancéreuse
|
|
WO2019023247A1
(fr)
|
2017-07-25 |
2019-01-31 |
Immutics, Inc. |
Traitement du cancer par blocage de l'interaction de tim-3 et de son ligand
|
|
EP3668874B1
(fr)
|
2017-08-18 |
2021-12-22 |
Medimmune Limited |
Conjugués de pyrrolobenzodiazépine
|
|
JP7273716B2
(ja)
|
2017-09-29 |
2023-05-15 |
第一三共株式会社 |
抗体－ピロロベンゾジアゼピン誘導体コンジュゲート
|
|
CN111417409B
(zh)
|
2017-11-14 |
2022-07-08 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂䓬缀合物
|
|
CN112204048A
(zh)
|
2017-12-15 |
2021-01-08 |
朱诺治疗学股份有限公司 |
抗cct5结合分子及其使用方法
|
|
TWI827575B
(zh)
|
2017-12-28 |
2024-01-01 |
美商伊繆諾金公司 |
苯二氮平衍生物
|
|
GB201803342D0
(en)
*
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
WO2019224340A1
(fr)
|
2018-05-25 |
2019-11-28 |
Medimmune Limited |
Conjugués de pyrrolobenzodiazépine
|
|
FR3081707A1
(fr)
|
2018-05-30 |
2019-12-06 |
Universite De Rouen Normandie |
Traitement des troubles neurologiques causes par l'alcoolisation foetale
|
|
AU2019301675B2
(en)
|
2018-07-12 |
2025-09-04 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Affinity matured CD22-specific monoclonal antibody and uses thereof
|
|
US12012463B2
(en)
|
2018-08-08 |
2024-06-18 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
High affinity monoclonal antibodies targeting glypican-2 and uses thereof
|
|
JP7259024B2
(ja)
|
2018-10-19 |
2023-04-17 |
メドイミューン・リミテッド |
ピロロベンゾジアゼピン複合体
|
|
AU2019363153A1
(en)
|
2018-10-19 |
2021-05-06 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
IL319265A
(en)
|
2018-12-21 |
2025-04-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and their uses
|
|
WO2020146182A1
(fr)
|
2019-01-08 |
2020-07-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps à domaine unique hétérospécifiques ciblant la mésothéline pour le traitement de tumeurs solides
|
|
WO2020154150A1
(fr)
|
2019-01-22 |
2020-07-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps monoclonaux à haute affinité ciblant le glypicane-1 et procédés d'utilisation
|
|
EP3918323A4
(fr)
|
2019-01-30 |
2022-12-28 |
TrueBinding, Inc. |
Anticorps anti-gal3 et leurs utilisations
|
|
MX2021010477A
(es)
|
2019-03-15 |
2021-10-01 |
Medimmune Ltd |
Dimeros de azetidobenzodiazepina y conjugados que los comprenden para uso en el tratamiento de cancer.
|
|
TW202102506A
(zh)
|
2019-03-29 |
2021-01-16 |
美商伊繆諾金公司 |
苯二氮平衍生物
|
|
CN119899265A
(zh)
|
2019-10-22 |
2025-04-29 |
美国政府(由卫生和人类服务部的部长所代表) |
用于治疗多种实体瘤的靶向b7h3（cd276）的高亲和力纳米抗体
|
|
AU2020402752A1
(en)
|
2019-12-12 |
2022-06-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibody-drug conjugates specific for CD276 and uses thereof
|
|
TW202144572A
(zh)
|
2020-03-19 |
2021-12-01 |
美商亞維代堤生物科學公司 |
治療臉肩胛肱骨肌肉失養症之組合物及方法
|
|
WO2021195469A1
(fr)
|
2020-03-27 |
2021-09-30 |
Avidity Biosciences, Inc. |
Compositions et procédés de traitement d'une dystrophie musculaire
|
|
WO2021242776A2
(fr)
|
2020-05-26 |
2021-12-02 |
Truebinding, Inc. |
Méthodes de traitement de maladies inflammatoires par blocage de la galectine-3
|
|
WO2022093745A1
(fr)
|
2020-10-26 |
2022-05-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps à domaine unique ciblant une protéine de spicule de coronavirus responsable du sars et leurs utilisations
|
|
WO2022232612A1
(fr)
|
2021-04-29 |
2022-11-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Nanocorps spécifiques du virus de lassa et leurs méthodes d'utilisation
|
|
CA3216228A1
(fr)
|
2021-06-09 |
2022-12-15 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps a domaine unique heterospecifiques ciblant pd-l1 pour le traitement de tumeurs solides
|
|
JP2024526764A
(ja)
|
2021-07-13 |
2024-07-19 |
トゥルーバインディング，インコーポレイテッド |
タンパク質凝集を防止する方法
|
|
CN118265544A
(zh)
|
2021-09-16 |
2024-06-28 |
艾维迪提生物科学公司 |
治疗面肩肱型肌营养不良的组合物和方法
|
|
JP2024541058A
(ja)
|
2021-11-03 |
2024-11-06 |
ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ． |
抗体の特異的共役
|
|
WO2023086768A1
(fr)
|
2021-11-09 |
2023-05-19 |
Truebinding, Inc. |
Méthodes de traitement ou d'inhibition de maladies cardiovasculaires
|
|
PE20242350A1
(es)
|
2022-05-03 |
2024-12-16 |
Genentech Inc |
Anticuerpos anti-ly6e, inmunoconjugados y usos de estos
|
|
WO2025019228A1
(fr)
|
2023-07-20 |
2025-01-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps monoclonaux entièrement humains et récepteurs antigéniques chimériques dirigés contre cd276 pour le traitement de tumeurs solides
|
|
WO2025171238A1
(fr)
|
2024-02-07 |
2025-08-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps monoclonaux qui se lient à la région juxtamembranaire de la mésothéline et leurs utilisations
|