DK1491212T3 - Middel til behandling af søvnforstyrrelser - Google Patents
Middel til behandling af søvnforstyrrelserInfo
- Publication number
- DK1491212T3 DK1491212T3 DK03715566.0T DK03715566T DK1491212T3 DK 1491212 T3 DK1491212 T3 DK 1491212T3 DK 03715566 T DK03715566 T DK 03715566T DK 1491212 T3 DK1491212 T3 DK 1491212T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- sleep disorders
- sleep
- disorders
- Prior art date
Links
- 208000019116 sleep disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/527—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim spiro-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002093398 | 2002-03-29 | ||
| PCT/JP2003/003925 WO2003082333A1 (en) | 2002-03-29 | 2003-03-28 | Remedy for sleep disturbance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1491212T3 true DK1491212T3 (da) | 2012-10-29 |
Family
ID=28671758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03715566.0T DK1491212T3 (da) | 2002-03-29 | 2003-03-28 | Middel til behandling af søvnforstyrrelser |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7566728B2 (da) |
| EP (1) | EP1491212B1 (da) |
| JP (1) | JP4056977B2 (da) |
| AU (1) | AU2003220886A1 (da) |
| DK (1) | DK1491212T3 (da) |
| ES (1) | ES2392340T3 (da) |
| PT (1) | PT1491212E (da) |
| WO (1) | WO2003082333A1 (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006025267A1 (ja) * | 2004-08-31 | 2006-03-09 | Mitsubishi Pharma Corporation | Per2タンパク質レベルの低下を作用機序とする睡眠障害治療薬 |
| DE602006019119D1 (de) | 2005-09-30 | 2011-02-03 | Glaxo Group Ltd | Verbindungen mit aktivität am m1-rezeptor und ihre verwendung in der medizin |
| EP1937670A1 (en) | 2005-09-30 | 2008-07-02 | Glaxo Group Limited | Benzimidazolones which have activity at m1 receptor |
| WO2007036718A2 (en) | 2005-09-30 | 2007-04-05 | Glaxo Group Limited | Compounds which have activity at m1 receptor and their uses in medicine |
| GB0605784D0 (en) * | 2006-03-22 | 2006-05-03 | Glaxo Group Ltd | Compounds |
| CA2666630C (en) * | 2006-10-16 | 2012-01-24 | Mitsubishi Tanabe Pharma Corporation | Agent for prophylaxis or treatment of alcohol dependence or drug dependence |
| JPWO2008102859A1 (ja) * | 2007-02-22 | 2010-05-27 | 田辺三菱製薬株式会社 | 不安障害の予防および/または治療薬 |
| CA2679530C (en) | 2007-03-01 | 2012-09-25 | Mitsubishi Tanabe Pharma Corporation | Benzimidazole compound and pharmaceutical use thereof |
| RU2451017C2 (ru) * | 2007-03-01 | 2012-05-20 | Мицубиси Танабе Фарма Корпорейшн | Бензимидазольное соединение и его фармацевтическое применение |
| JP5554709B2 (ja) | 2007-08-31 | 2014-07-23 | パーデュー、ファーマ、リミテッド、パートナーシップ | 置換キノキサリンタイプピペリジン化合物とその使用 |
| RU2500678C2 (ru) * | 2008-07-21 | 2013-12-10 | Пэдью Фарма Л.П. | Замещенные хиноксалинового типа мостиковые пиперидиновые соединения и их применение |
| TW201016675A (en) * | 2008-09-16 | 2010-05-01 | Mitsubishi Tanabe Pharma Corp | Crystalline benzoimidazole compound and salt thereof |
| WO2010090198A1 (ja) | 2009-02-03 | 2010-08-12 | 田辺三菱製薬株式会社 | 1-(4-ピペリジニル)ベンゾイミダゾロン誘導体の製造方法 |
| WO2014102589A1 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Quinazolin-4(3h)-one-type piperidine compounds and uses thereof |
| WO2014102594A2 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Substituted benzimidazole-type piperidine compounds and uses thereof |
| US9963458B2 (en) | 2012-12-27 | 2018-05-08 | Purdue Pharma L.P. | Indole and indoline-type piperidine compounds and uses thereof |
| WO2014102592A2 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Oxime/substituted quinoxaline-type piperidine compounds and uses thereof |
| WO2014102590A1 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Substituted piperidin-4-amino-type compounds and uses thereof |
| JP6359560B2 (ja) * | 2012-12-31 | 2018-07-18 | サノビオン ファーマシューティカルズ インクSunovion Pharmaceuticals Inc. | 複素環式化合物及びその使用方法 |
| JOP20190008A1 (ar) | 2016-07-26 | 2019-01-24 | Purdue Pharma Lp | علاج ومنع اضطرابات النوم |
| WO2019145850A1 (en) | 2018-01-24 | 2019-08-01 | Purdue Pharma L. P. | Sleep disorder treatment and prevention |
| CN115611856B (zh) * | 2021-07-14 | 2024-07-05 | 宜昌人福药业有限责任公司 | 一种哌啶衍生物及其药物组合物、制备方法和用途 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2226058C (en) | 1997-01-30 | 2008-01-29 | F. Hoffmann-La Roche Ag | 8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives |
| CA2291094C (en) | 1997-05-30 | 2008-02-26 | Banyu Pharmaceutical Co., Ltd. | 2-oxoimidazole derivative |
| ES2170446T3 (es) | 1997-12-05 | 2002-08-01 | Hoffmann La Roche | Derivados de 1,3,8-triaza-espiro(4,5)decan-4-ona. |
| US6166209A (en) | 1997-12-11 | 2000-12-26 | Hoffmann-La Roche Inc. | Piperidine derivatives |
| IL137149A0 (en) * | 1998-01-19 | 2001-07-24 | Pfizer | 4-(2-keto-1-benzimidazolinyl) piperidine compounds as orl1-receptor agonists |
| HUP0101275A3 (en) | 1998-03-26 | 2002-12-28 | Japan Tobacco Inc | Amide derivatives and pharmaceutical compositions containing them as nociceptin antagonists |
| KR100357541B1 (ko) | 1998-05-15 | 2002-10-18 | 주식회사종근당 | 5-데메톡시 푸마질롤 유도체 및 그 제조방법 |
| AU3809999A (en) | 1998-05-18 | 1999-12-06 | Novo Nordisk A/S | Novel 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes |
| US6277991B1 (en) | 1998-05-18 | 2001-08-21 | Novo Nordisk A/S | 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes |
| ES2162503T3 (es) * | 1998-06-12 | 2001-12-16 | Hoffmann La Roche | Derivados diaza-espiro(3,5)nonanos. |
| PT963985E (pt) | 1998-06-12 | 2003-06-30 | Hoffmann La Roche | Derivados de di- ou triaza-espiro(4,5)decano |
| ID29137A (id) | 1998-07-27 | 2001-08-02 | Schering Corp | Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1 |
| MA26659A1 (fr) | 1998-08-06 | 2004-12-20 | Pfizer | Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation. |
| JP2000053686A (ja) | 1998-08-12 | 2000-02-22 | Yushi Seihin Kk | フルオロアルキルアルコキシシラン及びその製造方法 |
| CO5150201A1 (es) | 1998-09-07 | 2002-04-29 | Hoffmann La Roche | Derivados de piperidina |
| EP0997464B1 (en) | 1998-10-23 | 2005-02-16 | Pfizer Inc. | 1,3,8-Triazaspiro[4,5] decanone compounds as orl1-receptor agonists |
| IT1303737B1 (it) | 1998-11-11 | 2001-02-23 | Smithkline Beecham Spa | Derivati fenilpiperidinici procedimento per la loro preparazione eloro uso come ligandi del recettore orl-1. |
| AU1185300A (en) | 1998-11-20 | 2000-06-13 | Banyu Pharmaceutical Co., Ltd. | 2-oxoimidazole derivatives |
| US6340681B1 (en) | 1999-07-16 | 2002-01-22 | Pfizer Inc | 2-benzimidazolylamine compounds as ORL-1-receptor agonists |
| JP2001058991A (ja) | 1999-08-20 | 2001-03-06 | Banyu Pharmaceut Co Ltd | スルホンアミド誘導体 |
| JP2003512372A (ja) * | 1999-10-18 | 2003-04-02 | スミスクライン ビーチャム パブリック リミテッド カンパニー | テトラヒドロベンゾインドロン誘導体、それらの製造および5−ht7受容体アンタゴニストとしてのそれらの使用 |
| WO2001039767A1 (en) | 1999-12-06 | 2001-06-07 | Euro-Celtique, S.A. | Tertiary amino compounds having opioid receptor affinity |
| ATE302770T1 (de) | 1999-12-06 | 2005-09-15 | Euro Celtique Sa | Benzimidazolverbindungen die nociceptinrezeptoraffinität haben |
| ATE306488T1 (de) | 2000-01-05 | 2005-10-15 | Pfizer | Benzimidazol-verbindungen zur verwendung als orl1-rezeptor-antagonisten |
| AU2001283955B2 (en) | 2000-07-31 | 2006-05-18 | F. Hoffmann-La Roche Ag | Piperazine derivatives |
| WO2002026714A1 (en) | 2000-09-27 | 2002-04-04 | Takeda Chemical Industries, Ltd. | Spiro compounds |
| YU82403A (sh) | 2001-04-18 | 2006-08-17 | Euroceltique S.A. | Jedinjenja spiropirazola |
| EP2033644A1 (en) | 2001-04-18 | 2009-03-11 | Euro-Celtique S.A. | Spiroindene and spiroindane compounds |
| JP4401076B2 (ja) | 2001-04-18 | 2010-01-20 | ユーロ−セルティーク エス.エイ. | ベンズイミダゾロン化合物 |
| JP4380992B2 (ja) | 2001-04-18 | 2009-12-09 | ユーロ−セルティーク エス.エイ. | ノシセプチン類似体 |
| US20030078278A1 (en) | 2001-06-26 | 2003-04-24 | Pfizer Inc. | Spiropiperidine compounds as ligands for ORL-1 receptor |
| US7192964B2 (en) * | 2001-07-23 | 2007-03-20 | Banyu Pharmaceutical Co., Ltd. | 4-oxoimidazolidine-2-spiropiperidine derivatives |
-
2003
- 2003-03-28 AU AU2003220886A patent/AU2003220886A1/en not_active Abandoned
- 2003-03-28 ES ES03715566T patent/ES2392340T3/es not_active Expired - Lifetime
- 2003-03-28 PT PT03715566T patent/PT1491212E/pt unknown
- 2003-03-28 JP JP2003579869A patent/JP4056977B2/ja not_active Expired - Fee Related
- 2003-03-28 EP EP03715566A patent/EP1491212B1/en not_active Expired - Lifetime
- 2003-03-28 DK DK03715566.0T patent/DK1491212T3/da active
- 2003-03-28 WO PCT/JP2003/003925 patent/WO2003082333A1/ja not_active Ceased
- 2003-03-28 US US10/508,339 patent/US7566728B2/en not_active Expired - Fee Related
-
2009
- 2009-04-28 US US12/453,057 patent/US8003669B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2003082333A1 (ja) | 2005-07-28 |
| EP1491212A1 (en) | 2004-12-29 |
| US7566728B2 (en) | 2009-07-28 |
| AU2003220886A1 (en) | 2003-10-13 |
| EP1491212B1 (en) | 2012-08-08 |
| PT1491212E (pt) | 2012-11-16 |
| JP4056977B2 (ja) | 2008-03-05 |
| EP1491212A4 (en) | 2009-10-28 |
| US8003669B2 (en) | 2011-08-23 |
| ES2392340T3 (es) | 2012-12-07 |
| WO2003082333A1 (en) | 2003-10-09 |
| US20050119308A1 (en) | 2005-06-02 |
| US20090253747A1 (en) | 2009-10-08 |
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