DK1334721T3 - Nateglinid-holdige hydrofile lægemiddelpræparater - Google Patents

Nateglinid-holdige hydrofile lægemiddelpræparater

Info

Publication number: DK1334721T3
Authority: DK; Denmark
Prior art keywords: nateglinide; preparation; containing hydrophilic; hydrophilic drug; drug preparations
Prior art date: 2000-10-24

Application number

DK01976818T

Other languages

Danish (da)

English (en)

Inventor

Nobutaka Ninomiya

Chisato Makino

Akira Yabuki

Original Assignee

Ajinomoto Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-24

Filing date

2001-10-23

Publication date

2009-07-06

2001-10-23 Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk

2009-07-06 Application granted granted Critical

2009-07-06 Publication of DK1334721T3 publication Critical patent/DK1334721T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK01976818T 2000-10-24 2001-10-23 Nateglinid-holdige hydrofile lægemiddelpræparater DK1334721T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2000324374		2000-10-24
PCT/JP2001/009292 WO2002040010A1 (fr)	2000-10-24	2001-10-23	Preparations de medicament contenant du nateglinide

Publications (1)

Publication Number	Publication Date
DK1334721T3 true DK1334721T3 (da)	2009-07-06

Family

ID=18801919

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01976818T DK1334721T3 (da)	2000-10-24	2001-10-23	Nateglinid-holdige hydrofile lægemiddelpræparater

Country Status (19)

Country	Link
US (1)	US20040029968A1 (ja)
EP (1)	EP1334721B1 (ja)
JP (3)	JPWO2002040010A1 (ja)
KR (1)	KR100829410B1 (ja)
CN (1)	CN100531730C (ja)
AT (1)	ATE429217T1 (ja)
AU (1)	AU2001296000A1 (ja)
BR (1)	BR0114897A (ja)
CA (1)	CA2426764C (ja)
CY (1)	CY1110320T1 (ja)
DE (1)	DE60138476D1 (ja)
DK (1)	DK1334721T3 (ja)
ES (1)	ES2321911T3 (ja)
MX (1)	MXPA03003686A (ja)
PT (1)	PT1334721E (ja)
RU (1)	RU2283104C2 (ja)
SI (1)	SI1334721T1 (ja)
TW (1)	TWI289461B (ja)
WO (1)	WO2002040010A1 (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2226901A (en) *	1999-12-28	2001-07-09	Ajinomoto Co., Inc.	Oral preparations for diabetes
DK1334720T3 (da) *	2000-10-24	2009-01-19	Ajinomoto Kk	Nateglinid-indeholdende fremstillinger
US6861553B2 (en)	2002-07-03	2005-03-01	Teva Pharmaceuticals Industries Ltd.	Process for preparing nateglinide and intermediates thereof
US7358390B2 (en)	2002-07-18	2008-04-15	Teva Pharmaceutical Industries Ltd.	Polymorphic forms of nateglinide
US7534913B2 (en)	2002-07-18	2009-05-19	Teva Pharmaceutica Industries Ltd.	Crystalline form of nateglinide
US7148376B2 (en)	2002-07-18	2006-12-12	Teva Pharmaceutical Industries Ltd.	Polymorphic forms of nateglinide
US7420084B2 (en)	2002-07-18	2008-09-02	Teva Pharmaceutical Industries Ltd.	Polymorphic forms of nateglinide
WO2005013964A1 (ja) *	2003-08-08	2005-02-17	Ajinomoto Co., Inc.	ナテグリニド含有製剤
WO2005020979A1 (en) *	2003-09-03	2005-03-10	Ranbaxy Laboratories Limited	A process for the preparation of pharmaceutical compositions of nateglinide
WO2005051360A1 (en) *	2003-11-28	2005-06-09	Ranbaxy Laboratories Limited	Pharmaceutical compositions comprising nateglinide and a surfactant
WO2005092319A1 (en) *	2004-03-29	2005-10-06	Ranbaxy Laboratories Limited	Rapidly disintegrating pharmaceutical compositions comprising nateglinide and a disintegrant
KR20120064735A (ko) *	2004-04-01	2012-06-19	아지노모토 가부시키가이샤	나테글리니드 함유 제제
US8586081B2 (en) *	2007-09-20	2013-11-19	University Of Massachusetts	Detoxified recombinant botulinum neurotoxin
WO2013066278A1 (en) *	2011-11-03	2013-05-10	Mahmut Bilgic	A process for production of pharmaceutical formulations comprising nateglinide
WO2013115739A1 (en) *	2012-01-31	2013-08-08	Mahmut Bilgic	Production method for formulations comprising comprising nateglinide and lipoic acid
CN115348863A (zh) *	2020-03-27	2022-11-15	辉瑞公司	以2-[(4-{6-[(4-氰基-2-氟苄基)氧基]吡啶-2-基}哌啶-1-基)甲基]-1-[(2s)-氧杂环丁烷-2-基甲基]-1h-苯并咪唑-6-甲酸或其药学上的盐治疗2型糖尿病或肥胖症或体重过重

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH066532B2 (ja) *	1983-09-29	1994-01-26	日産化学工業株式会社	親水性コロイドにより変性したワックス性微粉末
JPS6354321A (ja) *	1985-03-27	1988-03-08	Ajinomoto Co Inc	血糖降下剤
US5474989A (en) *	1988-11-11	1995-12-12	Kurita Water Industries, Ltd.	Drug composition
US5463116A (en) *	1991-07-30	1995-10-31	Ajinomoto Co., Inc.	Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them
EP0526171B1 (en) *	1991-07-30	1997-03-05	Ajinomoto Co., Inc.	Crystals of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine and methods for preparing them
JPH0696517B2 (ja)	1993-03-17	1994-11-30	日産化学工業株式会社	変性したワックス性微粉末で被覆された薬剤及びその製造法
JP2994956B2 (ja) *	1994-05-31	1999-12-27	信越化学工業株式会社	低置換度ヒドロキシプロピルセルロース、その組成物およびその錠剤
EP2277517A1 (en) *	1996-11-15	2011-01-26	Ajinomoto Co., Inc.	Nateglinide tablet composition
CA2216215A1 (en) *	1997-04-05	1998-10-05	Isa Odidi	Controlled release formulations using intelligent polymers having opposing wettability characteristics of hydrophobicity and hydrophilicity
JP3591801B2 (ja) *	1997-06-19	2004-11-24	田辺製薬株式会社	口腔内速崩壊性製剤の製法
JP2000178183A (ja) *	1998-12-17	2000-06-27	Lion Corp	固形製剤及びその製造方法
JP2000290171A (ja) *	1999-04-06	2000-10-17	Eisai Co Ltd	崩壊のはやい錠剤又はその製造方法
AU2226901A (en) *	1999-12-28	2001-07-09	Ajinomoto Co., Inc.	Oral preparations for diabetes
EP1283054A4 (en) *	2000-03-17	2006-04-12	Ajinomoto Kk	MEDICAMENTS FOR TREATING THE COMPLICATIONS OF DIABETES AND NEUROPATHIES AND USE THEREOF
ATE373635T1 (de) *	2000-10-18	2007-10-15	Ajinomoto Kk	Verfahren zur herstellung von acylphenylalaninen
KR100819358B1 (ko) *	2000-10-18	2008-04-04	아지노모토 가부시키가이샤	나테글리니드 결정의 제조방법
DK1334720T3 (da) *	2000-10-24	2009-01-19	Ajinomoto Kk	Nateglinid-indeholdende fremstillinger
WO2002034713A1 (en) *	2000-10-24	2002-05-02	Ajinomoto Co.,Inc.	Process for producing b-form nateglinide crystal
US6830759B2 (en) *	2002-06-28	2004-12-14	Ajinomoto Co., Inc.	Antidiabetic preparation for oral administration

2001
- 2001-10-23 AU AU2001296000A patent/AU2001296000A1/en not_active Abandoned
- 2001-10-23 DE DE60138476T patent/DE60138476D1/de not_active Expired - Lifetime
- 2001-10-23 PT PT01976818T patent/PT1334721E/pt unknown
- 2001-10-23 ES ES01976818T patent/ES2321911T3/es not_active Expired - Lifetime
- 2001-10-23 BR BR0114897-4A patent/BR0114897A/pt not_active IP Right Cessation
- 2001-10-23 AT AT01976818T patent/ATE429217T1/de active
- 2001-10-23 WO PCT/JP2001/009292 patent/WO2002040010A1/ja not_active Ceased
- 2001-10-23 MX MXPA03003686A patent/MXPA03003686A/es active IP Right Grant
- 2001-10-23 EP EP01976818A patent/EP1334721B1/en not_active Expired - Lifetime
- 2001-10-23 SI SI200130912T patent/SI1334721T1/sl unknown
- 2001-10-23 KR KR1020037005635A patent/KR100829410B1/ko not_active Expired - Fee Related
- 2001-10-23 TW TW090126184A patent/TWI289461B/zh not_active IP Right Cessation
- 2001-10-23 CN CNB018212182A patent/CN100531730C/zh not_active Expired - Fee Related
- 2001-10-23 JP JP2002542384A patent/JPWO2002040010A1/ja active Pending
- 2001-10-23 DK DK01976818T patent/DK1334721T3/da active
- 2001-10-23 CA CA2426764A patent/CA2426764C/en not_active Expired - Fee Related
- 2001-10-23 RU RU2003111949/15A patent/RU2283104C2/ru not_active IP Right Cessation
2003
- 2003-04-23 US US10/420,886 patent/US20040029968A1/en not_active Abandoned
2009
- 2009-06-11 CY CY20091100623T patent/CY1110320T1/el unknown
2010
- 2010-02-04 JP JP2010023025A patent/JP5278708B2/ja not_active Expired - Fee Related
2013
- 2013-01-11 JP JP2013003337A patent/JP5673972B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CY1110320T1 (el)	2015-01-14
JP5278708B2 (ja)	2013-09-04
TWI289461B (en)	2007-11-11
KR100829410B1 (ko)	2008-05-15
WO2002040010A1 (fr)	2002-05-23
DE60138476D1 (de)	2009-06-04
ATE429217T1 (de)	2009-05-15
PT1334721E (pt)	2009-06-01
JP2010095551A (ja)	2010-04-30
AU2001296000A1 (en)	2002-05-27
US20040029968A1 (en)	2004-02-12
CN1482904A (zh)	2004-03-17
JPWO2002040010A1 (ja)	2004-06-03
BR0114897A (pt)	2003-08-12
CA2426764A1 (en)	2003-04-23
EP1334721A4 (en)	2005-11-02
EP1334721A1 (en)	2003-08-13
JP2013064018A (ja)	2013-04-11
CN100531730C (zh)	2009-08-26
JP5673972B2 (ja)	2015-02-18
SI1334721T1 (sl)	2009-08-31
KR20030042028A (ko)	2003-05-27
MXPA03003686A (es)	2004-01-26
CA2426764C (en)	2010-04-20
EP1334721B1 (en)	2009-04-22
ES2321911T3 (es)	2009-06-15
RU2283104C2 (ru)	2006-09-10

Publication	Publication Date	Title
CY1110320T1 (el)	2015-01-14	Παρασκευασματα υδροφιλου φαρμακου περιεχοντα νατεγλινιδη (nateglinide)
ES2528359T3 (es)	2015-02-09	Procedimiento para la producción de una forma medicamentosa oral con desintegración y puesta en libertad inmediatas de las sustancias activas
BR9908121A (pt)	2000-10-24	Forma galênica de liberação imediata e de liberação prolongada administrável por via oral compreendendo um agente estimulador de absorção e utilização deste agente estimulador de absorção
AR029716A1 (es)	2003-07-10	Productos dermatologicos en forma de hoja
JP4387356B2 (ja)	2009-12-16	超音波導入スキンケアデバイス
BE899635A (fr)	1984-11-12	Compositions pharmaceutiques.
DE69414840D1 (de)	1999-01-07	Akzeptabele pharmazeutische zusammensetzung enthaltend einen alkohol und einen hydrophalischen wirkstoff
ES2075249T3 (es)	1995-10-01	Dispositivo adhesivo para la administracion transdermica de un agente activo.
BR9609663A (pt)	1999-05-18	Formulações para desprendimento controlado de medicamentos fracamente soluveis
DE68909772D1 (de)	1993-11-11	Diclofenac-Natrium-Arzneizubereitung mit verlängerter Wirkstoffabgabe.
DE69812690D1 (de)	2003-04-30	Arzneistoffverabreichungssystem auf basis von flüssigkristall-strukturen
KR20040002391A (ko)	2004-01-07	경구투여제 및 경구투여제 유지체
RU2000123567A (ru)	2002-11-10	Фармацевтическая композиция, содержащая в комбинации метформин и фибрат, и ее применение при приготовлении лекарственных средств, предназначенных для снижения гипергликемии
ES2403069T3 (es)	2013-05-13	Composición oral de liberación controlada que contiene levetiracetam
IT1246188B (it)	1994-11-16	Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute.
KR101489524B1 (ko)	2015-02-03	발포성 보습 조성물
EP0350701A3 (en)	1990-09-19	Pharmaceutical cmpositions for oral administration having analgesic and anti-inflammatory activity, possessing excellent palatability and being free of irritating effects on mucous membranes
AR039164A1 (es)	2005-02-09	Sales de venlafaxina de baja solubilidad en agua
AR062647A1 (es)	2008-11-26	Formulaciones farmaceutica y metodos de uso
CA2215327A1 (en)	1996-10-31	Formulations for lipophilic compounds
RU2003111949A (ru)	2004-08-27	Гидрофильный фармацевтический препарат, содержащий натеглинид
US20030064101A1 (en)	2003-04-03	Floating osmotic device for controlled release drug delivery
DE59509928D1 (de)	2002-01-24	Antihyperglykämisch wirksame Arzneimittel
JPH082801B2 (ja)	1996-01-17	経皮吸収促進剤及び皮膚外用剤
ES2186207T3 (es)	2003-05-01	Metodo para preparacion de formulaciones farmaceuticas.