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DK1331935T3 - Derivater af tryptamin og analoge forbindelser samt farmaceutiske formuleringer deraf - Google Patents

Derivater af tryptamin og analoge forbindelser samt farmaceutiske formuleringer deraf

Info

Publication number
DK1331935T3
DK1331935T3 DK01974651T DK01974651T DK1331935T3 DK 1331935 T3 DK1331935 T3 DK 1331935T3 DK 01974651 T DK01974651 T DK 01974651T DK 01974651 T DK01974651 T DK 01974651T DK 1331935 T3 DK1331935 T3 DK 1331935T3
Authority
DK
Denmark
Prior art keywords
tryptamine
derivatives
well
pharmaceutical formulations
analogous compounds
Prior art date
Application number
DK01974651T
Other languages
Danish (da)
English (en)
Inventor
Nava Zisapel
Moshe Laudon
Original Assignee
Neurim Pharma 1991
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurim Pharma 1991 filed Critical Neurim Pharma 1991
Application granted granted Critical
Publication of DK1331935T3 publication Critical patent/DK1331935T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK01974651T 2000-10-03 2001-09-25 Derivater af tryptamin og analoge forbindelser samt farmaceutiske formuleringer deraf DK1331935T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL138825A IL138825A (en) 2000-10-03 2000-10-03 Pharmaceutical preparations containing tryptamine derivatives and similar compounds, and such new compounds
PCT/IL2001/000898 WO2002028347A2 (fr) 2000-10-03 2001-09-25 Derives de tryptamines et composes analogues, et formulation pharmaceutique contenant de tels derives

Publications (1)

Publication Number Publication Date
DK1331935T3 true DK1331935T3 (da) 2009-02-02

Family

ID=11074694

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01974651T DK1331935T3 (da) 2000-10-03 2001-09-25 Derivater af tryptamin og analoge forbindelser samt farmaceutiske formuleringer deraf

Country Status (39)

Country Link
US (2) US6780884B2 (fr)
EP (1) EP1331935B1 (fr)
JP (1) JP2004533986A (fr)
KR (1) KR100855385B1 (fr)
CN (1) CN100518735C (fr)
AR (1) AR035587A1 (fr)
AT (1) ATE409474T1 (fr)
AU (1) AU9416201A (fr)
BG (1) BG107759A (fr)
BR (1) BR0114464A (fr)
CA (1) CA2423628C (fr)
CL (1) CL2001002303A1 (fr)
CR (1) CR6968A (fr)
CY (1) CY1110417T1 (fr)
CZ (1) CZ301098B6 (fr)
DE (1) DE60136003D1 (fr)
DK (1) DK1331935T3 (fr)
EA (1) EA005918B1 (fr)
EE (1) EE05192B1 (fr)
ES (1) ES2315307T3 (fr)
GT (1) GT200100197A (fr)
HN (1) HN2001000218A (fr)
HU (1) HU227163B1 (fr)
IL (1) IL138825A (fr)
IS (1) IS2607B (fr)
MX (1) MXPA03002612A (fr)
NO (1) NO20031396D0 (fr)
NZ (1) NZ525587A (fr)
PA (1) PA8529801A1 (fr)
PE (1) PE20020411A1 (fr)
PL (1) PL365679A1 (fr)
PT (1) PT1331935E (fr)
SI (1) SI1331935T1 (fr)
SK (1) SK4042003A3 (fr)
TW (1) TWI270544B (fr)
UA (1) UA75091C2 (fr)
UY (1) UY26946A1 (fr)
WO (1) WO2002028347A2 (fr)
ZA (1) ZA200303113B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1694323A4 (fr) * 2003-12-19 2009-05-13 Elixir Pharmaceuticals Inc Procedes de traitement d'un trouble
EP1715742A4 (fr) * 2004-02-20 2009-06-17 Lifescape Biosciences Inc Compositions et methodes de regulation du sommeil
US20070015814A1 (en) * 2005-06-10 2007-01-18 Ernest Kun Parp Modulators and Treatment of Cancer
US7622495B2 (en) 2006-10-03 2009-11-24 Neurim Pharmaceuticals (1991) Ltd. Substituted aryl-indole compounds and their kynurenine/kynuramine-like metabolites as therapeutic agents
WO2009003226A1 (fr) 2007-06-29 2009-01-08 Clarencew Pty Ltd Traitement ou prophylaxie de troubles neurologiques ou neuropsychiatriques par une administration oculaire
PT2291659E (pt) * 2008-05-13 2016-01-22 Univ Yale Moléculas quiméricas pequenas para o recrutamento de anticorpos contra células cancerosas
US8852630B2 (en) 2008-05-13 2014-10-07 Yale University Chimeric small molecules for the recruitment of antibodies to cancer cells
AU2012264320A1 (en) 2011-05-31 2014-01-23 Clarencew Pty.Ltd Methods for preventing and treating motor-related neurological conditions
WO2013063492A1 (fr) 2011-10-28 2013-05-02 Board Of Regents, The University Of Texas System Nouvelles compositions et procédés pour traiter le cancer
CN102816103B (zh) * 2012-08-20 2014-05-07 冉瑞琼 硫化天冬氨酸修饰的退黑素衍生物及其应用
RU2750989C2 (ru) * 2016-03-14 2021-07-07 Сомалоджик, Инк. Композиции и способы синтеза 5-(n-защищенного триптаминкарбоксамида)-2'-дезоксиуридинфосфорамидита для включения в нуклеиновую кислоту
CN116421600B (zh) * 2023-05-29 2024-08-23 重庆医科大学 色醇在制备治疗焦虑的药物中的应用
WO2025137730A1 (fr) * 2023-12-22 2025-06-26 Alexander Shulgin Research Institute, Inc. Tryptamines n-substituées et lysergamides n-substitués et leur utilisation comme agents thérapeutiques

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL79264A0 (en) * 1986-06-27 1986-09-30 Univ Ramot Tryptamine derivatives,pharmaceutical compositions containing them and their use in an assay for melatonin receptors
AUPO274596A0 (en) * 1996-10-04 1996-10-31 Armstrong, Stuart Maxwell Method for the treatment of neurological or neuropsychiatric disorders
US6310085B1 (en) * 1997-10-03 2001-10-30 Clarencew Pty Ltd. Method for the treatment of neurological or neuropsychiatric disorders

Also Published As

Publication number Publication date
EE05192B1 (et) 2009-08-17
IS6752A (is) 2003-03-21
NZ525587A (en) 2005-03-24
JP2004533986A (ja) 2004-11-11
CL2001002303A1 (es) 2010-06-25
IL138825A0 (en) 2001-10-31
US6780884B2 (en) 2004-08-24
EA005918B1 (ru) 2005-06-30
MXPA03002612A (es) 2004-04-02
CA2423628A1 (fr) 2002-04-11
IL138825A (en) 2006-06-11
CZ2003940A3 (cs) 2003-10-15
US20040029950A1 (en) 2004-02-12
CN100518735C (zh) 2009-07-29
EA200300436A1 (ru) 2003-10-30
NO20031396L (no) 2003-03-27
AU9416201A (en) 2002-04-15
WO2002028347A3 (fr) 2002-07-04
KR20030051689A (ko) 2003-06-25
ZA200303113B (en) 2004-07-23
PL365679A1 (en) 2005-01-10
PA8529801A1 (es) 2002-12-30
KR100855385B1 (ko) 2008-09-04
AR035587A1 (es) 2004-06-16
ES2315307T3 (es) 2009-04-01
PT1331935E (pt) 2009-01-19
EP1331935A2 (fr) 2003-08-06
NO20031396D0 (no) 2003-03-27
IS2607B (is) 2010-04-15
UY26946A1 (es) 2001-11-30
CA2423628C (fr) 2011-04-26
HUP0302616A2 (hu) 2003-11-28
EE200300135A (et) 2003-08-15
EP1331935A4 (fr) 2004-12-01
SI1331935T1 (sl) 2009-04-30
ATE409474T1 (de) 2008-10-15
WO2002028347A2 (fr) 2002-04-11
EP1331935B1 (fr) 2008-10-01
CZ301098B6 (cs) 2009-11-04
HK1074163A1 (zh) 2005-11-04
CR6968A (es) 2004-02-25
GT200100197A (es) 2002-05-08
UA75091C2 (en) 2006-03-15
CN1582147A (zh) 2005-02-16
SK4042003A3 (en) 2003-09-11
CY1110417T1 (el) 2015-04-29
HN2001000218A (es) 2002-05-09
TWI270544B (en) 2007-01-11
US20050020664A1 (en) 2005-01-27
DE60136003D1 (de) 2008-11-13
HU227163B1 (en) 2010-09-28
BR0114464A (pt) 2004-01-20
BG107759A (bg) 2004-01-30
PE20020411A1 (es) 2002-05-16

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