EA200300436A1 - Производные триптамина и аналогичные соединения и содержащие их фармацевтические композиции - Google Patents
Производные триптамина и аналогичные соединения и содержащие их фармацевтические композицииInfo
- Publication number
- EA200300436A1 EA200300436A1 EA200300436A EA200300436A EA200300436A1 EA 200300436 A1 EA200300436 A1 EA 200300436A1 EA 200300436 A EA200300436 A EA 200300436A EA 200300436 A EA200300436 A EA 200300436A EA 200300436 A1 EA200300436 A1 EA 200300436A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- conditions
- disorders
- pharmaceutical compositions
- compounds
- derivatives
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- APJYDQYYACXCRM-UHFFFAOYSA-N tryptamine Chemical class C1=CC=C2C(CCN)=CNC2=C1 APJYDQYYACXCRM-UHFFFAOYSA-N 0.000 title 1
- 208000019116 sleep disease Diseases 0.000 abstract 2
- 208000011580 syndromic disease Diseases 0.000 abstract 2
- 208000027534 Emotional disease Diseases 0.000 abstract 1
- 208000001456 Jet Lag Syndrome Diseases 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 230000002920 convulsive effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001932 seasonal effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Это изобретение касается новых замещенных триптаминов и родственных производных, а также фармацевтических композиций, приготовленных из них. Эти соединения, композиции и их соли могут применяться для получения лекарственных средств для взаимодействия с мелатонинэргической системой. Эти соединения и условия могут применяться для лечения нескольких типов медицинских состояний, таких как заболевания центральной нервной системы и психические расстройства (нарушения сна, эпилепсия и другие судорожные синдромы, страх, нейродегенеративные болезни), нарушения биологического ритма (синдром смены часовых поясов, синдром позднего засыпания, нарушения сна при ночной работе по сменному графику, сезонные эмоциональные расстройства), неопластические состояния и состояния, связанные с физиологическим старением.Отчет о международном поиске был опубликован 2002.07.04.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL138825A IL138825A (en) | 2000-10-03 | 2000-10-03 | Pharmaceutical preparations containing tryptamine derivatives and similar compounds, and such new compounds |
| PCT/IL2001/000898 WO2002028347A2 (en) | 2000-10-03 | 2001-09-25 | Derivatives of tryptamine and analogous compounds, and pharmaceutical formulations containing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200300436A1 true EA200300436A1 (ru) | 2003-10-30 |
| EA005918B1 EA005918B1 (ru) | 2005-06-30 |
Family
ID=11074694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200300436A EA005918B1 (ru) | 2000-10-03 | 2001-09-25 | Производные триптамина и их аналоги, и содержащие их фармацевтические композиции |
Country Status (39)
| Country | Link |
|---|---|
| US (2) | US6780884B2 (ru) |
| EP (1) | EP1331935B1 (ru) |
| JP (1) | JP2004533986A (ru) |
| KR (1) | KR100855385B1 (ru) |
| CN (1) | CN100518735C (ru) |
| AR (1) | AR035587A1 (ru) |
| AT (1) | ATE409474T1 (ru) |
| AU (1) | AU9416201A (ru) |
| BG (1) | BG107759A (ru) |
| BR (1) | BR0114464A (ru) |
| CA (1) | CA2423628C (ru) |
| CL (1) | CL2001002303A1 (ru) |
| CR (1) | CR6968A (ru) |
| CY (1) | CY1110417T1 (ru) |
| CZ (1) | CZ301098B6 (ru) |
| DE (1) | DE60136003D1 (ru) |
| DK (1) | DK1331935T3 (ru) |
| EA (1) | EA005918B1 (ru) |
| EE (1) | EE05192B1 (ru) |
| ES (1) | ES2315307T3 (ru) |
| GT (1) | GT200100197A (ru) |
| HN (1) | HN2001000218A (ru) |
| HU (1) | HU227163B1 (ru) |
| IL (1) | IL138825A (ru) |
| IS (1) | IS2607B (ru) |
| MX (1) | MXPA03002612A (ru) |
| NO (1) | NO20031396L (ru) |
| NZ (1) | NZ525587A (ru) |
| PA (1) | PA8529801A1 (ru) |
| PE (1) | PE20020411A1 (ru) |
| PL (1) | PL365679A1 (ru) |
| PT (1) | PT1331935E (ru) |
| SI (1) | SI1331935T1 (ru) |
| SK (1) | SK4042003A3 (ru) |
| TW (1) | TWI270544B (ru) |
| UA (1) | UA75091C2 (ru) |
| UY (1) | UY26946A1 (ru) |
| WO (1) | WO2002028347A2 (ru) |
| ZA (1) | ZA200303113B (ru) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007515429A (ja) * | 2003-12-19 | 2007-06-14 | エリクシアー ファーマシューティカルズ， インコーポレイテッド | 障害を治療する方法 |
| EP1715742A4 (en) * | 2004-02-20 | 2009-06-17 | Lifescape Biosciences Inc | COMPOSITIONS AND METHODS FOR SLEEPING |
| KR20080031266A (ko) * | 2005-06-10 | 2008-04-08 | 바이파 사이언스 인코포레이티드 | Ｐａｒｐ 조절제 및 암의 치료 |
| US7622495B2 (en) | 2006-10-03 | 2009-11-24 | Neurim Pharmaceuticals (1991) Ltd. | Substituted aryl-indole compounds and their kynurenine/kynuramine-like metabolites as therapeutic agents |
| CA2729006C (en) | 2007-06-29 | 2017-01-31 | Clarencew Pty Ltd | Treatment or prophylaxis of neurological or neuropsychiatric disorders via ocular administration |
| DK2291659T3 (en) * | 2008-05-13 | 2015-12-21 | Univ Yale | SMALL CHEMICAL MOLECULES FOR RECRUITING ANTIBODIES TO CANCER CELLS |
| US8852630B2 (en) | 2008-05-13 | 2014-10-07 | Yale University | Chimeric small molecules for the recruitment of antibodies to cancer cells |
| KR102407182B1 (ko) | 2011-05-31 | 2022-06-10 | 클라렌슈 피티와이 리미티드 | 광선 요법 장치 |
| US9073851B2 (en) | 2011-10-28 | 2015-07-07 | Board Of Regents, The University Of Texas System | Compositions and methods for treating cancer |
| CN102816103B (zh) * | 2012-08-20 | 2014-05-07 | 冉瑞琼 | 硫化天冬氨酸修饰的退黑素衍生物及其应用 |
| TWI733772B (zh) * | 2016-03-14 | 2021-07-21 | 美商身體邏輯股份有限公司 | 用於合成吲哚環核鹼基結合物之組成物及方法 |
| CN116421600B (zh) * | 2023-05-29 | 2024-08-23 | 重庆医科大学 | 色醇在制备治疗焦虑的药物中的应用 |
| WO2025137730A1 (en) * | 2023-12-22 | 2025-06-26 | Alexander Shulgin Research Institute, Inc. | N-substituted tryptamines and n-substituted lysergamides and their use as therapeutic agents |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL79264A0 (en) * | 1986-06-27 | 1986-09-30 | Univ Ramot | Tryptamine derivatives,pharmaceutical compositions containing them and their use in an assay for melatonin receptors |
| AUPO274596A0 (en) * | 1996-10-04 | 1996-10-31 | Armstrong, Stuart Maxwell | Method for the treatment of neurological or neuropsychiatric disorders |
| US6310085B1 (en) * | 1997-10-03 | 2001-10-30 | Clarencew Pty Ltd. | Method for the treatment of neurological or neuropsychiatric disorders |
-
2000
- 2000-10-03 IL IL138825A patent/IL138825A/en not_active IP Right Cessation
-
2001
- 2001-09-14 TW TW090122940A patent/TWI270544B/zh not_active IP Right Cessation
- 2001-09-25 JP JP2002531973A patent/JP2004533986A/ja active Pending
- 2001-09-25 UY UY26946A patent/UY26946A1/es not_active Application Discontinuation
- 2001-09-25 UA UA2003043421A patent/UA75091C2/uk unknown
- 2001-09-25 PT PT01974651T patent/PT1331935E/pt unknown
- 2001-09-25 WO PCT/IL2001/000898 patent/WO2002028347A2/en not_active Ceased
- 2001-09-25 HU HU0302616A patent/HU227163B1/hu not_active IP Right Cessation
- 2001-09-25 SI SI200130889T patent/SI1331935T1/sl unknown
- 2001-09-25 DK DK01974651T patent/DK1331935T3/da active
- 2001-09-25 NZ NZ525587A patent/NZ525587A/en unknown
- 2001-09-25 BR BR0114464-2A patent/BR0114464A/pt not_active Application Discontinuation
- 2001-09-25 CL CL2001002303A patent/CL2001002303A1/es unknown
- 2001-09-25 AR ARP010104520A patent/AR035587A1/es unknown
- 2001-09-25 DE DE60136003T patent/DE60136003D1/de not_active Expired - Lifetime
- 2001-09-25 SK SK404-2003A patent/SK4042003A3/sk unknown
- 2001-09-25 EE EEP200300135A patent/EE05192B1/xx not_active IP Right Cessation
- 2001-09-25 KR KR1020037004661A patent/KR100855385B1/ko not_active Expired - Fee Related
- 2001-09-25 CA CA2423628A patent/CA2423628C/en not_active Expired - Fee Related
- 2001-09-25 EP EP01974651A patent/EP1331935B1/en not_active Expired - Lifetime
- 2001-09-25 CZ CZ20030940A patent/CZ301098B6/cs not_active IP Right Cessation
- 2001-09-25 EA EA200300436A patent/EA005918B1/ru not_active IP Right Cessation
- 2001-09-25 CN CNB018168043A patent/CN100518735C/zh not_active Expired - Fee Related
- 2001-09-25 AT AT01974651T patent/ATE409474T1/de active
- 2001-09-25 AU AU9416201A patent/AU9416201A/xx not_active Withdrawn
- 2001-09-25 PL PL01365679A patent/PL365679A1/xx not_active Application Discontinuation
- 2001-09-25 ES ES01974651T patent/ES2315307T3/es not_active Expired - Lifetime
- 2001-09-25 MX MXPA03002612A patent/MXPA03002612A/es active IP Right Grant
- 2001-09-25 US US10/381,976 patent/US6780884B2/en not_active Expired - Fee Related
- 2001-09-26 PE PE2001000960A patent/PE20020411A1/es not_active Application Discontinuation
- 2001-09-27 GT GT200100197A patent/GT200100197A/es unknown
- 2001-10-01 PA PA20018529801A patent/PA8529801A1/es unknown
- 2001-10-02 HN HN2001000218A patent/HN2001000218A/es unknown
-
2003
- 2003-03-21 IS IS6752A patent/IS2607B/is unknown
- 2003-03-27 NO NO20031396A patent/NO20031396L/no not_active Application Discontinuation
- 2003-04-23 ZA ZA200303113A patent/ZA200303113B/xx unknown
- 2003-04-24 BG BG107759A patent/BG107759A/bg unknown
- 2003-05-02 CR CR6968A patent/CR6968A/es unknown
-
2004
- 2004-08-20 US US10/921,823 patent/US20050020664A1/en not_active Abandoned
-
2008
- 2008-12-22 CY CY20081101480T patent/CY1110417T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA200100524A1 (ru) | Амиды антраниловой кислоты и их применение в качестве лекарственных средств | |
| EA200300436A1 (ru) | Производные триптамина и аналогичные соединения и содержащие их фармацевтические композиции | |
| RU93058531A (ru) | Фторалкоксибензиламинные производные азотсодержащих гетероциклов, фармацевтическая композиция, способ лечения | |
| EA200000592A1 (ru) | Азаполициклические соединения, конденсированные с арилом | |
| ES2119124T3 (es) | Bencimidazoles utiles para el tratamiento de trastornos del sistema nervioso. | |
| DE69429527D1 (de) | Inhibitoren von beta-amyloid-protein-herstellung | |
| BR9713186A (pt) | Inibidores de metaloprotease 1,3-diheterocìclicos | |
| BR9810841A (pt) | Inibidores de metaloprotease alicìclicos | |
| EA200500782A1 (ru) | Лечение геморрагического шока | |
| DE3779500D1 (de) | Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen. | |
| EA200500169A1 (ru) | Замещенные производные 1,3-дифенилпроп-2-ен-1-она, получение и применение | |
| EA200200716A1 (ru) | Арилконденсированные азаполициклические соединения | |
| DE69736441D1 (de) | Pharmazeutische zusammensetzung zur behandlung von neurologischen und neuropsychiatrischen erkrankungen | |
| CY1118313T1 (el) | Παραγωγα καρβοστυρυλιου και σταθεροποιητες της διαθεσης για αντιμετωπιση διαταραχων της διαθεσης | |
| EA200100127A1 (ru) | Производные фенилксантина | |
| ATE142877T1 (de) | Melatoninderivate zur behandlung von schlafstörungen und zur pre-anästhesie | |
| ATE266675T1 (de) | Troponin untereinheiten und fragmente zur verwendung als inhibitoren der angiogenese | |
| ATE492279T1 (de) | Bupropinmetaboliten zur behandlung von dementia und anderen zerebrovasckulären erkrankungen | |
| SV1995000007A (es) | Derivados del acido micofenolico 5-substituidos. | |
| BR9713178A (pt) | Inbidores espirocìclicos da metaloprotease. | |
| DE60112766D1 (de) | Verwendung von derivaten der valproinsäureamide und 2-valproinsäureamid zur behandlung und prävention von schmerzen und/oder kopfschmerzen | |
| BR0316723A (pt) | Derivados de anilinopirazol úteis para o tratamento de diabetes | |
| EA199900542A1 (ru) | Соединения сульфоновой кислоты или сульфониламино-n-(гетероаралкил)-азагетероциклиламида | |
| EA200000741A1 (ru) | Новые производные дигидроксигексановой кислоты | |
| ATE192923T1 (de) | Verwendung von boswelliasäure zur behandlung von hirntumoren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |
|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): RU |