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DK1318978T3 - N-acylsulfonamid-apoptosis-promotorer - Google Patents

N-acylsulfonamid-apoptosis-promotorer

Info

Publication number
DK1318978T3
DK1318978T3 DK01971244T DK01971244T DK1318978T3 DK 1318978 T3 DK1318978 T3 DK 1318978T3 DK 01971244 T DK01971244 T DK 01971244T DK 01971244 T DK01971244 T DK 01971244T DK 1318978 T3 DK1318978 T3 DK 1318978T3
Authority
DK
Denmark
Prior art keywords
apoptosis promoters
acylsulfonamide
acylsulfonamide apoptosis
promoters
apoptosis
Prior art date
Application number
DK01971244T
Other languages
English (en)
Inventor
Xilu Wang
David J Augeri
Daniel A Dickman
Juergen Dinges
Stephen W Fesik
Saul H Rosenberg
Wang Shen
Sheela A Thomas
Michael D Wendt
William Mcclellan
Thorsten Oost
Milan Bruncko
Steven A Baumeister
Hong Ding
Philip J Hajduk
Aaron R Kunzer
David G Nettesheim
Andrew M Petros
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/935,581 external-priority patent/US20020055631A1/en
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK1318978T3 publication Critical patent/DK1318978T3/da

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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
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    • C07C323/37—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group the sulfur atom of the sulfide group being further bound to a carbon atom of a six-membered aromatic ring
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    • C07C2602/14—All rings being cycloaliphatic
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    • C07C2602/00—Systems containing two condensed rings
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    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
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    • C07C2602/44—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing eight carbon atoms
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    • C07C2603/58—Ring systems containing bridged rings containing three rings
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DK01971244T 2000-09-20 2001-09-20 N-acylsulfonamid-apoptosis-promotorer DK1318978T3 (da)

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US09/935,581 US20020055631A1 (en) 2000-09-20 2001-08-24 N-acylsulfonamide apoptosis promoters

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BR0110101A (pt) 2005-06-07
UY26942A1 (es) 2002-04-26
JP2004529852A (ja) 2004-09-30
EP1318978A2 (en) 2003-06-18
CA2423103A1 (en) 2002-03-28
AR031130A1 (es) 2003-09-10
CA2423103C (en) 2010-08-24
DE60117157T2 (de) 2006-09-21
WO2002024636A3 (en) 2002-09-26
MXPA03002477A (es) 2004-09-10
ATE317382T1 (de) 2006-02-15
ES2258102T3 (es) 2006-08-16
JP5086513B2 (ja) 2012-11-28
AU2001291151A1 (en) 2002-04-02
PT1318978E (pt) 2006-06-30
DE60117157D1 (de) 2006-04-20
BRPI0110101B1 (pt) 2016-08-23
WO2002024636A2 (en) 2002-03-28
EP1318978B1 (en) 2006-02-08
CY1105016T1 (el) 2009-11-04
HK1058031A1 (en) 2004-04-30

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