DK1392328T3 - Medikament til beskyttelse i radioterapi - Google Patents
Medikament til beskyttelse i radioterapiInfo
- Publication number
- DK1392328T3 DK1392328T3 DK02717355T DK02717355T DK1392328T3 DK 1392328 T3 DK1392328 T3 DK 1392328T3 DK 02717355 T DK02717355 T DK 02717355T DK 02717355 T DK02717355 T DK 02717355T DK 1392328 T3 DK1392328 T3 DK 1392328T3
- Authority
- DK
- Denmark
- Prior art keywords
- radiotherapy
- medication
- protection
- relates
- protectant
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000001959 radiotherapy Methods 0.000 title 1
- 102000019197 Superoxide Dismutase Human genes 0.000 abstract 2
- 108010012715 Superoxide dismutase Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000011275 oncology therapy Methods 0.000 abstract 1
- 229940124553 radioprotectant Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26239001P | 2001-01-19 | 2001-01-19 | |
| PCT/US2002/001507 WO2002060383A2 (fr) | 2001-01-19 | 2002-01-22 | Therapie anticancereuse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1392328T3 true DK1392328T3 (da) | 2009-11-09 |
Family
ID=22997293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02717355T DK1392328T3 (da) | 2001-01-19 | 2002-01-22 | Medikament til beskyttelse i radioterapi |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20030050297A1 (fr) |
| EP (1) | EP1392328B1 (fr) |
| JP (3) | JP2004520380A (fr) |
| AT (1) | ATE439134T1 (fr) |
| AU (1) | AU2002248366B2 (fr) |
| CA (1) | CA2436245C (fr) |
| DE (1) | DE60233317D1 (fr) |
| DK (1) | DK1392328T3 (fr) |
| ES (1) | ES2330728T3 (fr) |
| WO (1) | WO2002060383A2 (fr) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1156478C (zh) * | 1999-01-25 | 2004-07-07 | 国家犹太医疗及研究中心 | 取代的卟啉 |
| JP2005508864A (ja) | 2001-06-01 | 2005-04-07 | ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター | 糖尿病の治療、または移植術における使用、または免疫寛容の誘導のためのオキシダントスカベンジャー |
| GB2397067B (en) * | 2002-12-23 | 2005-05-11 | Destiny Pharma Ltd | Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation |
| FR2863892B1 (fr) * | 2003-12-18 | 2007-05-11 | Univ Paris Descartes | Utilisation de mimetiques de la superoxyde dismutase et de la glutathion reductase comme anti-cancereux |
| EP1718201B1 (fr) | 2004-02-09 | 2016-09-14 | Duke University | Porphyrines substituees |
| EP1731150A4 (fr) * | 2004-03-04 | 2010-06-16 | Makoto Yuasa | Niosome ayant un complexe porphyrine metallique y incorporee, procede pour la production de celle-ci et medicament utilisant celui-ci |
| GB2415372A (en) | 2004-06-23 | 2005-12-28 | Destiny Pharma Ltd | Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent |
| AU2007308141B2 (en) | 2006-10-12 | 2013-08-29 | Galera Labs, Llc | Methods of treating oral mucositis |
| US8987245B2 (en) | 2008-04-02 | 2015-03-24 | Jonathan R. Brestoff Parker | Composition and method for affecting obesity and related conditions |
| US8598150B1 (en) | 2008-04-02 | 2013-12-03 | Jonathan R. Brestoff | Composition and method for affecting obesity and related conditions |
| AU2009280042B2 (en) | 2008-05-23 | 2015-06-04 | National Jewish Health | Methods for treating injury associated with exposure to an alkylating species |
| US10039722B2 (en) | 2008-10-14 | 2018-08-07 | Bioelectron Technology Corporation | Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the function of red cells |
| ES2355784B1 (es) * | 2009-09-21 | 2012-02-03 | Universitat De Valencia | Complejos metalicos mimeticos de sod |
| CN103906756B (zh) * | 2011-09-26 | 2020-03-03 | 加莱拉实验室有限责任公司 | 用于治疗疾病的方法 |
| KR20140109386A (ko) | 2011-12-02 | 2014-09-15 | 더 리전츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코퍼레이트 | 금속포르피린 신경 치료 |
| CN102617581B (zh) * | 2012-03-15 | 2013-11-06 | 中国药科大学 | 58Fe氯高铁血红素、其制备及其在药动学研究中的应用 |
| JP6154231B2 (ja) * | 2013-07-22 | 2017-06-28 | 学校法人同志社 | 抗癌剤 |
| SMT202000377T1 (it) | 2015-08-11 | 2020-09-10 | Galera Labs Llc | Complessi ad anello macrociclico pentaaza che possiedono biodisponibilita' orale |
| CN109414454A (zh) | 2016-05-03 | 2019-03-01 | 加莱拉实验室有限责任公司 | 用于癌症治疗的组合疗法 |
| CA3035766A1 (fr) | 2016-09-01 | 2018-03-08 | Galera Labs, Llc | Polytherapie anticancereuse avec complexe de cycle macrocyclique pentaaza et compose ascorbate |
| EP3606614B1 (fr) * | 2017-04-04 | 2025-05-21 | Biomimetix JV LLC | Méthodes, compositions et kits pour traiter et/ou prévenir un effet secondaire associé à une exposition à un rayonnement et/ou à une chimiothérapie |
| IL269915B (en) | 2017-04-13 | 2022-09-01 | Galera Labs Llc | Cancer immunotherapy combined with a macrocyclic ring pentase complex |
| MX2020002958A (es) | 2017-09-29 | 2020-08-20 | Univ Duke | Compuestos de porfirina sustituidos con fluoro, composiciones farmaceuticas que comprenden los mismos y metodos de preparacion y uso de los mismos. |
| WO2019152661A1 (fr) * | 2018-01-31 | 2019-08-08 | Galera Labs, Llc | Polythérapie anticancéreuse au moyen d'un complexe de type cycle macrocyclique pentaaza et d'un agent anticancéreux à base de platine |
| TWI669120B (zh) * | 2018-05-17 | 2019-08-21 | 國立交通大學 | 鎳超氧歧化酶擬態化合物用於製備癌症治療藥物的用途 |
| US12201649B2 (en) | 2021-11-12 | 2025-01-21 | Villanova University | Pharmaceutical composition comprising oxidizable biphenol and manganese porphyrin, and method of using the same |
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| DE3464252D1 (en) * | 1983-06-03 | 1987-07-23 | Hoffmann La Roche | Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation |
| US4829984A (en) * | 1983-12-15 | 1989-05-16 | Gordon Robert T | Method for the improvement of transplantation techniques and for the preservation of tissue |
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| US5087438A (en) * | 1984-07-03 | 1992-02-11 | Gordon Robert T | Method for affecting intracellular and extracellular electric and magnetic dipoles |
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| US4866054A (en) * | 1986-05-13 | 1989-09-12 | Chai-Tech Corporation | Antioxidant metallo-organic treatment of inflammation |
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| ES2083357T3 (es) | 1987-03-14 | 1996-04-16 | Boehringer Ingelheim Int | Manganeso-superoxido-dismutasa humana (hmn-sod). |
| US5227405A (en) * | 1987-03-31 | 1993-07-13 | Duke University | Superoxide dismutase mimic |
| US5223538A (en) | 1987-03-31 | 1993-06-29 | Duke University | Superoxide dismutase mimic |
| US4892941A (en) * | 1987-04-17 | 1990-01-09 | Dolphin David H | Porphyrins |
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| US5109016A (en) * | 1988-05-23 | 1992-04-28 | Georgia State University Foundation, Inc. | Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions |
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| US5202317A (en) * | 1990-09-13 | 1993-04-13 | The Regents Of The University Of California | Synthetic drug molecules that mimic metalloenzymes |
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| FR2676738B1 (fr) | 1991-05-22 | 1995-05-05 | Ir2M | Nouveau derive organique de metal de transition a structure porphyrinique, composition therapeutique le contenant, en particulier a activite hypoglycemiante. |
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| US6566517B2 (en) * | 2001-06-06 | 2003-05-20 | Brookhaven Science Associates, Llc | Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy |
-
2002
- 2002-01-22 EP EP02717355A patent/EP1392328B1/fr not_active Expired - Lifetime
- 2002-01-22 ES ES02717355T patent/ES2330728T3/es not_active Expired - Lifetime
- 2002-01-22 AU AU2002248366A patent/AU2002248366B2/en not_active Ceased
- 2002-01-22 DE DE60233317T patent/DE60233317D1/de not_active Expired - Lifetime
- 2002-01-22 WO PCT/US2002/001507 patent/WO2002060383A2/fr not_active Ceased
- 2002-01-22 JP JP2002560579A patent/JP2004520380A/ja not_active Withdrawn
- 2002-01-22 US US10/051,367 patent/US20030050297A1/en not_active Abandoned
- 2002-01-22 CA CA2436245A patent/CA2436245C/fr not_active Expired - Fee Related
- 2002-01-22 AT AT02717355T patent/ATE439134T1/de not_active IP Right Cessation
- 2002-01-22 DK DK02717355T patent/DK1392328T3/da active
-
2006
- 2006-11-09 US US11/558,408 patent/US8765729B2/en not_active Expired - Fee Related
-
2009
- 2009-07-08 JP JP2009162200A patent/JP2009242421A/ja active Pending
-
2012
- 2012-01-27 JP JP2012015864A patent/JP2012087148A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ES2330728T3 (es) | 2009-12-15 |
| JP2012087148A (ja) | 2012-05-10 |
| EP1392328A4 (fr) | 2004-11-17 |
| ATE439134T1 (de) | 2009-08-15 |
| EP1392328B1 (fr) | 2009-08-12 |
| US20070149498A1 (en) | 2007-06-28 |
| CA2436245A1 (fr) | 2002-08-08 |
| JP2004520380A (ja) | 2004-07-08 |
| WO2002060383A2 (fr) | 2002-08-08 |
| AU2002248366B2 (en) | 2006-10-26 |
| US8765729B2 (en) | 2014-07-01 |
| WO2002060383A3 (fr) | 2003-12-11 |
| CA2436245C (fr) | 2013-04-23 |
| US20030050297A1 (en) | 2003-03-13 |
| JP2009242421A (ja) | 2009-10-22 |
| DE60233317D1 (de) | 2009-09-24 |
| EP1392328A2 (fr) | 2004-03-03 |
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