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DK1383750T3 - Urinstofderivater som integrin a4 antagonister - Google Patents

Urinstofderivater som integrin a4 antagonister

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Publication number
DK1383750T3
DK1383750T3 DK02710010T DK02710010T DK1383750T3 DK 1383750 T3 DK1383750 T3 DK 1383750T3 DK 02710010 T DK02710010 T DK 02710010T DK 02710010 T DK02710010 T DK 02710010T DK 1383750 T3 DK1383750 T3 DK 1383750T3
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DK
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Prior art keywords
integrin
antagonists
urea derivatives
urea
derivatives
Prior art date
Application number
DK02710010T
Other languages
English (en)
Inventor
Mayorga Juan Miguel Jimenez
Ontoria Jesus Maria Ontoria
Tana Jordi Bach
Romero Eloisa Navarro
Original Assignee
Almirall Lab
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Publication of DK1383750T3 publication Critical patent/DK1383750T3/da

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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
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    • C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
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DK02710010T 2001-01-19 2002-01-15 Urinstofderivater som integrin a4 antagonister DK1383750T3 (da)

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HUP0303722A3 (en) 2005-12-28
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NO20033269L (no) 2003-09-19
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US20070238763A1 (en) 2007-10-11
ATE374191T1 (de) 2007-10-15
PL369120A1 (en) 2005-04-18
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CZ20031964A3 (cs) 2004-01-14
ES2291448T3 (es) 2008-03-01
AU2002228048B2 (en) 2008-03-13
ECSP034707A (es) 2003-10-28
HUP0303722A2 (hu) 2004-03-01
WO2002057242A2 (en) 2002-07-25
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