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DK1374952T3 - Anvendelse af flumazenil ved udvikling af et lægemiddel til behandling af alkoholafhængighed - Google Patents

Anvendelse af flumazenil ved udvikling af et lægemiddel til behandling af alkoholafhængighed

Info

Publication number
DK1374952T3
DK1374952T3 DK02716090T DK02716090T DK1374952T3 DK 1374952 T3 DK1374952 T3 DK 1374952T3 DK 02716090 T DK02716090 T DK 02716090T DK 02716090 T DK02716090 T DK 02716090T DK 1374952 T3 DK1374952 T3 DK 1374952T3
Authority
DK
Denmark
Prior art keywords
flumazenil
drug
alcohol dependence
development
treatment
Prior art date
Application number
DK02716090T
Other languages
Danish (da)
English (en)
Inventor
Ibanez Juan Jose Legarda
Original Assignee
Hythiam Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hythiam Inc filed Critical Hythiam Inc
Application granted granted Critical
Publication of DK1374952T3 publication Critical patent/DK1374952T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK02716090T 2001-01-17 2002-01-10 Anvendelse af flumazenil ved udvikling af et lægemiddel til behandling af alkoholafhængighed DK1374952T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200100106 2001-01-17

Publications (1)

Publication Number Publication Date
DK1374952T3 true DK1374952T3 (da) 2007-01-02

Family

ID=8496426

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02716090T DK1374952T3 (da) 2001-01-17 2002-01-10 Anvendelse af flumazenil ved udvikling af et lægemiddel til behandling af alkoholafhængighed

Country Status (22)

Country Link
US (2) US7348321B2 (fr)
EP (1) EP1374952B1 (fr)
JP (2) JP2004519461A (fr)
KR (1) KR100712570B1 (fr)
CN (1) CN1486205A (fr)
AT (1) ATE338575T1 (fr)
AU (1) AU2002226427B2 (fr)
BR (1) BR0206549A (fr)
CA (1) CA2433833C (fr)
CR (1) CR7049A (fr)
CY (1) CY1107500T1 (fr)
DE (1) DE60214527T2 (fr)
DK (1) DK1374952T3 (fr)
ES (1) ES2269661T3 (fr)
IL (1) IL156798A0 (fr)
MX (1) MXPA03006411A (fr)
NZ (2) NZ527583A (fr)
PT (1) PT1374952E (fr)
RU (1) RU2300378C2 (fr)
UA (1) UA78199C2 (fr)
WO (1) WO2002056964A1 (fr)
ZA (1) ZA200305922B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050192271A1 (en) 2003-07-15 2005-09-01 Hythiam, Inc. Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse
US20060172996A1 (en) * 2005-02-03 2006-08-03 Halikas James A Method of preventing relapse in the abstinent substance dependent individual
US20060172998A1 (en) * 2005-02-03 2006-08-03 Halikas James A Method of preventing relapse in the abstinent substance dependent individual
AU2006235318A1 (en) * 2005-04-07 2006-10-19 Hythiam, Inc. Improved methods of and compositions for the prevention of anxiety, substance abuse, and dependence
US20060263304A1 (en) * 2005-05-23 2006-11-23 Halikas James A Method of controlling alcohol intake and reversing alcohol effects
MX391921B (es) * 2007-08-06 2025-03-21 Biotie Therapies Inc Nepicastat para usarse en el tratamiento de dependencia
US20110034442A1 (en) * 2007-08-08 2011-02-10 Jaun Jose Legarda Ibanez Use and Methods of Use for an Antagonist of the Serotin3 Receptor (5-HT3) and a Selective Modulator of Chloride Channels for the Treatment of Addiction to or Dependence on Medicines/Drugs or Nervous System Disorders
WO2010094074A1 (fr) * 2009-02-20 2010-08-26 Palmaya Pty Ltd Préparation pharmaceutique et système d'administation
US8930050B2 (en) * 2009-04-29 2015-01-06 Marine Canada Acquisition Inc. Method and system for increasing or decreasing engine throttle in a marine vessel
US20100280684A1 (en) * 2009-04-29 2010-11-04 Pierre Garon Synchronization of shift and throttle controls in a marine vessel
US8387589B2 (en) * 2009-04-29 2013-03-05 Marine Canada Acqusition Inc. Position sensor for an output shaft used in a shift and throttle system
US8347859B2 (en) * 2009-04-29 2013-01-08 Marine Canada Acquisition Inc. Automatic throttle calibration in a marine vessel
US8406944B2 (en) * 2010-02-10 2013-03-26 Pierre Garon Control system and method for starting and stopping marine engines
US8182396B2 (en) * 2010-02-10 2012-05-22 Marine Canada Acquisition In.c Method and system for delaying shift and throttle commands based on engine speed in a marine vessel
US8845490B2 (en) 2010-02-10 2014-09-30 Marine Canada Acquisition Inc. Method and system for delaying shift and throttle commands based on engine speed in a marine vessel
WO2012114342A1 (fr) 2011-02-23 2012-08-30 Coeruleus Ltd. Complexes de flumazénil, compositions les comprenant et leurs utilisations
RU2468799C1 (ru) * 2011-08-03 2012-12-10 Общество с ограниченной ответственностью "Урал Крафт" Способ купирования алкогольного абстинентного синдрома посредством блокады бензодиазепиновых рецепторов

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
US5519017A (en) * 1990-03-29 1996-05-21 Lts Lohmann Therapie-Systeme Gmbh + Co. Kg Pharmaceutic formulation for the treatment of alcoholism
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use
GB9420010D0 (en) * 1994-10-01 1994-11-16 Marck Sharp & Dohme Limited Nucleic acids
US20030176456A1 (en) * 2001-12-21 2003-09-18 June Harry L. Methods for reducing alcohol cravings in chronic alcoholics
US6740677B2 (en) * 2002-08-19 2004-05-25 Hong Xue Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2′ hydroxyflavonoids

Also Published As

Publication number Publication date
CA2433833C (fr) 2009-06-02
MXPA03006411A (es) 2004-12-02
US7348321B2 (en) 2008-03-25
KR100712570B1 (ko) 2007-05-02
RU2003125274A (ru) 2005-01-20
BR0206549A (pt) 2004-02-25
HK1061661A1 (en) 2004-09-30
CR7049A (es) 2008-02-20
EP1374952A1 (fr) 2004-01-02
PT1374952E (pt) 2006-12-29
UA78199C2 (en) 2007-03-15
CY1107500T1 (el) 2013-03-13
ES2269661T3 (es) 2007-04-01
IL156798A0 (en) 2004-02-08
DE60214527D1 (de) 2006-10-19
CN1486205A (zh) 2004-03-31
US20080132492A1 (en) 2008-06-05
WO2002056964A1 (fr) 2002-07-25
DE60214527T2 (de) 2007-04-05
JP2004519461A (ja) 2004-07-02
CA2433833A1 (fr) 2002-07-25
ATE338575T1 (de) 2006-09-15
US20040092509A1 (en) 2004-05-13
NZ539400A (en) 2006-04-28
NZ527583A (en) 2006-03-31
JP2008201796A (ja) 2008-09-04
KR20040020046A (ko) 2004-03-06
ZA200305922B (en) 2004-08-02
EP1374952B1 (fr) 2006-09-06
RU2300378C2 (ru) 2007-06-10
AU2002226427B2 (en) 2006-11-16

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