DK1358179T3 - Syntesefremgangsmåde og mellemprodukter af pyridin-2-yl-methylamin - Google Patents
Syntesefremgangsmåde og mellemprodukter af pyridin-2-yl-methylaminInfo
- Publication number
- DK1358179T3 DK1358179T3 DK02706839T DK02706839T DK1358179T3 DK 1358179 T3 DK1358179 T3 DK 1358179T3 DK 02706839 T DK02706839 T DK 02706839T DK 02706839 T DK02706839 T DK 02706839T DK 1358179 T3 DK1358179 T3 DK 1358179T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyridin
- methylamine
- intermediates
- synthetic process
- cyanohydrins
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- SVEUVITYHIHZQE-UHFFFAOYSA-N n-methylpyridin-2-amine Chemical compound CNC1=CC=CC=N1 SVEUVITYHIHZQE-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title 1
- 238000005576 amination reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/38—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0101784A FR2820743B1 (fr) | 2001-02-09 | 2001-02-09 | Procede et intermediaires de synthese pour la preparation de derives de pyridin-2-yl-methylamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1358179T3 true DK1358179T3 (da) | 2006-09-11 |
Family
ID=8859834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02706839T DK1358179T3 (da) | 2001-02-09 | 2002-02-11 | Syntesefremgangsmåde og mellemprodukter af pyridin-2-yl-methylamin |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7208603B2 (da) |
| EP (1) | EP1358179B1 (da) |
| JP (1) | JP4259113B2 (da) |
| AT (1) | ATE325794T1 (da) |
| CA (1) | CA2437813C (da) |
| CY (1) | CY1105526T1 (da) |
| DE (1) | DE60211303T2 (da) |
| DK (1) | DK1358179T3 (da) |
| ES (1) | ES2263769T3 (da) |
| FR (1) | FR2820743B1 (da) |
| PT (1) | PT1358179E (da) |
| WO (1) | WO2002064585A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2840900B1 (fr) * | 2002-06-18 | 2005-02-25 | Pf Medicament | Nouveaux derives d'aryl[4-halogeno-4- [(heteroaryl-methylamino)-methyl]-piperidin-1-yl]-methanone, leur procede de preparation et leur utilisation a titre de medicaments |
| FR2891274B1 (fr) * | 2005-09-27 | 2007-11-23 | Pierre Fabre Medicament Sa | Procede de preparation du (3-chloro-4-fluoro-phenyl)-(4- fluoro-4-{[(5-methyl-pyrimidin-2-ylmethyl)-amino]-methyl}- piperidin-1-yl)-methanone et nouveaux derives pyrimidiniques intermediaires. |
| US8389534B2 (en) * | 2008-05-19 | 2013-03-05 | The University Of Tennessee Research Foundation | Pyrimidine non-classical cannabinoid compounds and related methods of use |
| JP2011520975A (ja) * | 2008-05-19 | 2011-07-21 | ユニヴァーシティ オブ テネシー リサーチ ファウンデーション，ザ | ピリミジンの非古典的カンナビノイド化合物及び関連する使用方法 |
| US10548885B2 (en) | 2014-07-09 | 2020-02-04 | Pierre Fabre Medicament | Method for treating movement disorders with befiradol |
| CN105566214B (zh) * | 2014-10-17 | 2020-05-15 | 上海医药工业研究院 | 3-[2-(3-氯苯基)乙基]-2-吡啶甲酸的制备工艺 |
| US10626105B2 (en) | 2016-09-22 | 2020-04-21 | Auspex Pharmaceuticals, Inc. | Deuterium-substituted pyridin- and pyrimidin-2-yl-methylamine compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4482437A (en) * | 1984-04-05 | 1984-11-13 | Reilly Tar & Chemical Corp. | Electrochemical reductions of cyanopyridine bases |
| PL327919A1 (en) * | 1995-12-29 | 1999-01-04 | Smithkline Beecham Corp | Antagonists of vitronectin receptors |
| AU3461497A (en) * | 1996-07-17 | 1998-02-09 | Nippon Kayaku Kabushiki Kaisha | Novel nitrogen monoxide synthetase inhibitors |
| FR2755967B1 (fr) * | 1996-11-21 | 1999-01-29 | Pf Medicament | Derives de la pyridin-2-yl-methylamine, leur procede de preparation et leur application comme medicaments |
-
2001
- 2001-02-09 FR FR0101784A patent/FR2820743B1/fr not_active Expired - Fee Related
-
2002
- 2002-02-11 AT AT02706839T patent/ATE325794T1/de active
- 2002-02-11 EP EP02706839A patent/EP1358179B1/fr not_active Expired - Lifetime
- 2002-02-11 PT PT02706839T patent/PT1358179E/pt unknown
- 2002-02-11 JP JP2002564516A patent/JP4259113B2/ja not_active Expired - Lifetime
- 2002-02-11 US US10/467,467 patent/US7208603B2/en not_active Expired - Lifetime
- 2002-02-11 ES ES02706839T patent/ES2263769T3/es not_active Expired - Lifetime
- 2002-02-11 DE DE60211303T patent/DE60211303T2/de not_active Expired - Lifetime
- 2002-02-11 CA CA2437813A patent/CA2437813C/fr not_active Expired - Lifetime
- 2002-02-11 WO PCT/FR2002/000508 patent/WO2002064585A1/fr not_active Ceased
- 2002-02-11 DK DK02706839T patent/DK1358179T3/da active
-
2006
- 2006-08-07 CY CY20061101108T patent/CY1105526T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1358179E (pt) | 2006-09-29 |
| DE60211303T2 (de) | 2007-04-26 |
| CA2437813C (fr) | 2011-04-19 |
| ES2263769T3 (es) | 2006-12-16 |
| FR2820743A1 (fr) | 2002-08-16 |
| CA2437813A1 (fr) | 2002-08-22 |
| FR2820743B1 (fr) | 2005-02-25 |
| JP4259113B2 (ja) | 2009-04-30 |
| EP1358179B1 (fr) | 2006-05-10 |
| JP2004519472A (ja) | 2004-07-02 |
| ATE325794T1 (de) | 2006-06-15 |
| EP1358179A1 (fr) | 2003-11-05 |
| DE60211303D1 (de) | 2006-06-14 |
| US20040116705A1 (en) | 2004-06-17 |
| CY1105526T1 (el) | 2010-07-28 |
| WO2002064585A1 (fr) | 2002-08-22 |
| US7208603B2 (en) | 2007-04-24 |
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