DK1347743T3 - Præparat til behandling af inflammatoriske lidelser - Google Patents
Præparat til behandling af inflammatoriske lidelserInfo
- Publication number
- DK1347743T3 DK1347743T3 DK01991836T DK01991836T DK1347743T3 DK 1347743 T3 DK1347743 T3 DK 1347743T3 DK 01991836 T DK01991836 T DK 01991836T DK 01991836 T DK01991836 T DK 01991836T DK 1347743 T3 DK1347743 T3 DK 1347743T3
- Authority
- DK
- Denmark
- Prior art keywords
- inflammatory disorders
- vesicle
- treatment
- preparation
- mole percent
- Prior art date
Links
- 208000027866 inflammatory disease Diseases 0.000 title abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 3
- 239000002502 liposome Substances 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
- Y10S977/797—Lipid particle
- Y10S977/798—Lipid particle having internalized material
- Y10S977/799—Containing biological material
- Y10S977/801—Drug
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
- Y10S977/907—Liposome
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Dispersion Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00204372 | 2000-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1347743T3 true DK1347743T3 (da) | 2006-07-03 |
Family
ID=8172392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01991836T DK1347743T3 (da) | 2000-12-07 | 2001-12-07 | Præparat til behandling af inflammatoriske lidelser |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7955618B2 (fr) |
| EP (1) | EP1347743B1 (fr) |
| JP (1) | JP4623931B2 (fr) |
| AT (1) | ATE319428T1 (fr) |
| AU (2) | AU3169702A (fr) |
| CA (1) | CA2430897C (fr) |
| DE (1) | DE60117858T2 (fr) |
| DK (1) | DK1347743T3 (fr) |
| ES (1) | ES2260321T3 (fr) |
| PT (1) | PT1347743E (fr) |
| WO (1) | WO2002045688A2 (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1347743T3 (da) | 2000-12-07 | 2006-07-03 | Univ Utrecht Holding Bv | Præparat til behandling af inflammatoriske lidelser |
| US7635463B2 (en) * | 2002-02-27 | 2009-12-22 | Pharmain Corporation | Compositions for delivery of therapeutics and other materials |
| EP1371362A1 (fr) * | 2002-06-12 | 2003-12-17 | Universiteit Utrecht Holding B.V. | Composition pour le traitement de troubles inflammatoires |
| EP1393720A1 (fr) * | 2002-08-27 | 2004-03-03 | Universiteit Utrecht | Vesicules encapsulant des corticosteroides pour le traitement du cancer |
| EP1655022A4 (fr) * | 2003-08-01 | 2010-04-07 | Nat Inst Of Advanced Ind Scien | Remede contre les maladies inflammatoires ou produit pour les diagnostiquer, contenant des liposomes cibleurs |
| US20050255154A1 (en) | 2004-05-11 | 2005-11-17 | Lena Pereswetoff-Morath | Method and composition for treating rhinitis |
| US8932627B2 (en) * | 2004-09-09 | 2015-01-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Liposomal compositions of glucocorticoid and glucocorticoid derivatives |
| CN106075449A (zh) | 2005-07-14 | 2016-11-09 | 尼奥塞蒂克斯公司 | 用于局部脂肪组织治疗的持续释放的增强性脂肪分解性制剂 |
| EP2077830B1 (fr) * | 2006-10-17 | 2012-11-07 | Lithera, Inc. | Procédés, compositions, et formulations pour le traitement de la maladie de l'oeil liée à la thyroïde |
| WO2009073146A2 (fr) * | 2007-11-29 | 2009-06-11 | Celgene Corporation | Utilisation de composés immunomodulateurs destinés au traitement de la myélite transverse, de la sclérose en plaques et d'autres troubles |
| EP2127639A1 (fr) | 2008-05-26 | 2009-12-02 | Universiteit Utrecht Holding B.V. | Liposomes contenant des corticostéroïdes pour le traitement des maladies cardiovasculaires |
| US20100016265A1 (en) * | 2008-07-16 | 2010-01-21 | Qaiser Yusuf | Anti-inflammatory composition and method for preparation |
| US9132084B2 (en) | 2009-05-27 | 2015-09-15 | Neothetics, Inc. | Methods for administration and formulations for the treatment of regional adipose tissue |
| JP2013517294A (ja) * | 2010-01-15 | 2013-05-16 | リセラ，インク． | 凍結乾燥ケーキ製剤 |
| WO2012074856A2 (fr) | 2010-11-24 | 2012-06-07 | Lithera, Inc. | Formulations monothérapeutiques d'agonistes bêta sélectifs, lipophiles et à action prolongée, et procédés de traitement cosmétique de l'adiposité et du renflement de la silhouette |
| AU2012331702B2 (en) | 2011-11-04 | 2017-10-26 | Laurentia Holding B.V. | Liposomal corticosteroids for treatment of inflammatory disorders in humans |
| US9186326B2 (en) * | 2014-07-21 | 2015-11-17 | Kimia Zist Parsian (Kzp) | Method and system for synthesizing nanocarrier based long acting drug delivery system for dexamethasone |
| HK1258650A1 (zh) | 2015-09-14 | 2019-11-15 | Vgsk Technologies, Inc. | 皮下、舌下和口服治疗用空间稳定载体、用於治疗哺乳动物的组合物和方法 |
| JP2019515925A (ja) | 2016-04-29 | 2019-06-13 | エンセラドゥス ファーマセウティカルス べー．フェー． | 炎症性病変又は領域に局所注射するためのリポソーム化コルチコステロイド |
| PE20230606A1 (es) * | 2020-03-02 | 2023-04-10 | Pharma Mar Sa | Compuestos para su uso en infecciones viricas |
| CA3217928A1 (fr) | 2021-05-05 | 2022-11-10 | Kameswari S. Konduri | Inhibition de la replication du sars-cov-2 et reduction de l'inflammation pulmonaire par corticosteriods encapsules dans des liposomes |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2002185A (en) * | 1930-06-26 | 1935-05-21 | Prosperity Co Inc | Garment or ironing press |
| GB1575343A (en) * | 1977-05-10 | 1980-09-17 | Ici Ltd | Method for preparing liposome compositions containing biologically active compounds |
| US4522803A (en) * | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
| US4994443A (en) * | 1982-12-20 | 1991-02-19 | The Children's Medical Center Corporation | Inhibition of angiogenesis |
| US5192528A (en) * | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
| IL79114A (en) | 1985-08-07 | 1990-09-17 | Allergan Pharma | Method and composition for making liposomes |
| DE3542773A1 (de) * | 1985-12-04 | 1987-06-11 | Roehm Pharma Gmbh | Hautwirksame pharmaka mit liposomen als wirkstofftraeger |
| US4818537A (en) * | 1986-10-21 | 1989-04-04 | Liposome Technology, Inc. | Liposome composition for treating dry eye |
| IL91664A (en) * | 1988-09-28 | 1993-05-13 | Yissum Res Dev Co | Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release |
| US5139803A (en) * | 1989-02-09 | 1992-08-18 | Nabisco, Inc. | Method and liposome composition for the stabilization of oxidizable substances |
| FR2648462B1 (fr) * | 1989-06-15 | 1994-01-28 | Oreal | Procede pour ameliorer l'efficacite therapeutique de corticosteroides liposolubles et composition pour la mise en oeuvre de ce procede |
| US5356633A (en) * | 1989-10-20 | 1994-10-18 | Liposome Technology, Inc. | Method of treatment of inflamed tissues |
| US5585112A (en) * | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
| US5474765A (en) * | 1992-03-23 | 1995-12-12 | Ut Sw Medical Ctr At Dallas | Preparation and use of steroid-polyanionic polymer-based conjugates targeted to vascular endothelial cells |
| US5989586A (en) | 1992-10-05 | 1999-11-23 | Cygnus, Inc. | Two-phase matrix for sustained release drug delivery device |
| CA2120197A1 (fr) * | 1993-04-02 | 1994-10-03 | Kenji Endo | Dispersions aqueuses stables renfermant des liposomes |
| JPH07316040A (ja) * | 1994-03-29 | 1995-12-05 | Res Dev Corp Of Japan | 再構成リポソームと物質導入方法 |
| US5786344A (en) * | 1994-07-05 | 1998-07-28 | Arch Development Corporation | Camptothecin drug combinations and methods with reduced side effects |
| JPH08198777A (ja) * | 1995-01-25 | 1996-08-06 | Taisho Pharmaceut Co Ltd | 注射用脂肪乳剤 |
| DE69635866T2 (de) * | 1995-12-15 | 2006-11-09 | Koninklijke Philips Electronics N.V. | Flüssigkristallanzeigevorrichtung |
| JPH09278672A (ja) * | 1996-04-12 | 1997-10-28 | Green Cross Corp:The | 薬物含有脂肪乳剤 |
| CA2229892C (fr) * | 1996-06-18 | 2003-01-07 | Kyowa Hakko Kogyo Co., Ltd. | Preparations liposomes de derives indolocarbazole |
| AU714992B2 (en) * | 1996-08-23 | 2000-01-13 | Alza Corporation | Liposomes containing a cisplatin compound |
| US6120751A (en) * | 1997-03-21 | 2000-09-19 | Imarx Pharmaceutical Corp. | Charged lipids and uses for the same |
| US6090800A (en) * | 1997-05-06 | 2000-07-18 | Imarx Pharmaceutical Corp. | Lipid soluble steroid prodrugs |
| US5758659A (en) | 1997-03-26 | 1998-06-02 | Thompson; Robert B. | Wound tab condom and method of application |
| US20020159951A1 (en) | 1997-05-06 | 2002-10-31 | Unger Evan C. | Novel targeted compositions for diagnostic and therapeutic use |
| WO1998050041A1 (fr) | 1997-05-06 | 1998-11-12 | Imarx Pharmaceutical Corp. | Nouveaux promedicaments renfermant des amphiphiles fluores |
| US6506783B1 (en) * | 1997-05-16 | 2003-01-14 | The Procter & Gamble Company | Cancer treatments and pharmaceutical compositions therefor |
| US6316260B1 (en) * | 1997-08-22 | 2001-11-13 | Bernina Biosystems Gmbh | Tetraether lipid derivatives and liposomes and lipid agglomerates containing tetraether lipid derivatives, and use thereof |
| EP1044679B1 (fr) * | 1998-11-02 | 2012-12-26 | Terumo Kabushiki Kaisha | Liposomes Stables pour la Délivrance Ciblée de Médicaments |
| RU2207844C2 (ru) | 1998-12-23 | 2003-07-10 | Идеа Аг. | УСОВЕРШЕНСТВОВАННЫЙ ПРЕПАРАТ ДЛЯ МЕСТНОГО НЕИНВАЗИВНОГО ПРИМЕНЕНИЯ in vivo |
| US6270806B1 (en) * | 1999-03-03 | 2001-08-07 | Elan Pharma International Limited | Use of peg-derivatized lipids as surface stabilizers for nanoparticulate compositions |
| ES2327025T3 (es) | 1999-06-25 | 2009-10-23 | Terumo Kabushiki Kaisha | Liposomas. |
| MXPA02000402A (es) * | 1999-07-14 | 2002-07-30 | Alza Corp | Lipopolimeros neutros y composiciones liposomales que contienen los mismos. |
| EP1072617A1 (fr) | 1999-07-30 | 2001-01-31 | Universiteit van Utrecht | Polymères sensibles à la température |
| US6511676B1 (en) * | 1999-11-05 | 2003-01-28 | Teni Boulikas | Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes |
| US20030050236A1 (en) * | 2000-08-15 | 2003-03-13 | The University Of Chicago | Compounds that enhance tumor death |
| TWI230616B (en) * | 2000-09-25 | 2005-04-11 | Ind Tech Res Inst | Liposome for incorporating large amounts of hydrophobic substances |
| DK1347743T3 (da) | 2000-12-07 | 2006-07-03 | Univ Utrecht Holding Bv | Præparat til behandling af inflammatoriske lidelser |
| US20050152962A1 (en) * | 2002-06-12 | 2005-07-14 | Metselaar Josbert M. | Composition for treatment of inflammatory disorders |
| EP1371362A1 (fr) | 2002-06-12 | 2003-12-17 | Universiteit Utrecht Holding B.V. | Composition pour le traitement de troubles inflammatoires |
| EP1393720A1 (fr) | 2002-08-27 | 2004-03-03 | Universiteit Utrecht | Vesicules encapsulant des corticosteroides pour le traitement du cancer |
-
2001
- 2001-12-07 DK DK01991836T patent/DK1347743T3/da active
- 2001-12-07 WO PCT/EP2001/014633 patent/WO2002045688A2/fr not_active Ceased
- 2001-12-07 ES ES01991836T patent/ES2260321T3/es not_active Expired - Lifetime
- 2001-12-07 PT PT01991836T patent/PT1347743E/pt unknown
- 2001-12-07 AU AU3169702A patent/AU3169702A/xx active Pending
- 2001-12-07 AU AU2002231697A patent/AU2002231697B2/en not_active Ceased
- 2001-12-07 EP EP01991836A patent/EP1347743B1/fr not_active Expired - Lifetime
- 2001-12-07 CA CA2430897A patent/CA2430897C/fr not_active Expired - Lifetime
- 2001-12-07 JP JP2002547474A patent/JP4623931B2/ja not_active Expired - Fee Related
- 2001-12-07 DE DE60117858T patent/DE60117858T2/de not_active Expired - Lifetime
- 2001-12-07 AT AT01991836T patent/ATE319428T1/de active
-
2003
- 2003-06-05 US US10/455,257 patent/US7955618B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE319428T1 (de) | 2006-03-15 |
| WO2002045688A2 (fr) | 2002-06-13 |
| AU3169702A (en) | 2002-06-18 |
| WO2002045688A3 (fr) | 2002-11-14 |
| EP1347743B1 (fr) | 2006-03-08 |
| CA2430897A1 (fr) | 2002-06-13 |
| CA2430897C (fr) | 2010-11-16 |
| DE60117858T2 (de) | 2006-11-30 |
| ES2260321T3 (es) | 2006-11-01 |
| JP2004517835A (ja) | 2004-06-17 |
| AU2002231697B2 (en) | 2006-09-07 |
| US20040037875A1 (en) | 2004-02-26 |
| DE60117858D1 (de) | 2006-05-04 |
| PT1347743E (pt) | 2006-06-30 |
| EP1347743A2 (fr) | 2003-10-01 |
| JP4623931B2 (ja) | 2011-02-02 |
| US7955618B2 (en) | 2011-06-07 |
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