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BR9712329A - Veículos contendo um éter lipídio/combinação de lipídio formado complementarmente e os usos terapêuticos dos mesmos - Google Patents

Veículos contendo um éter lipídio/combinação de lipídio formado complementarmente e os usos terapêuticos dos mesmos

Info

Publication number
BR9712329A
BR9712329A BR9712329-3A BR9712329A BR9712329A BR 9712329 A BR9712329 A BR 9712329A BR 9712329 A BR9712329 A BR 9712329A BR 9712329 A BR9712329 A BR 9712329A
Authority
BR
Brazil
Prior art keywords
lipid
ether
therapeutic uses
combination
vehicles
Prior art date
Application number
BR9712329-3A
Other languages
English (en)
Inventor
Walter Perkins
Eric Mayhew
J Craig Franklin
Andrew S Janoff
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of BR9712329A publication Critical patent/BR9712329A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Patente de Invenção: <B>"VEìCULOS CONTENDO UM éTER LIPìDIO/COMBINAçãO DE LIPìDIO FORMADO COMPLEMENTARMENTE E OS USOS TERAPêUTICOS DOS MESMOS".<D> São proporcionados neste relatório veículos com base em lipídio que tem um componente lamelar de lipídio composto de um éter lipídio e um lipídio formatado de modo complementar. Esta nova combinação de lipídios permite a incorporação dos éter lipídios no veículo em concentrações mais elevadas do que seria possível de outra forma. As composições farmacêuticas contendo os veículos podem ser usadas de forma terapêutica, por exemplo, no tratamento de canceres.
BR9712329-3A 1996-10-15 1997-10-15 Veículos contendo um éter lipídio/combinação de lipídio formado complementarmente e os usos terapêuticos dos mesmos BR9712329A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/720,997 US5932242A (en) 1996-10-15 1996-10-15 Ether lipid-containing pharmaceutical compositions and therapeutic uses thereof
PCT/US1997/018546 WO1998016200A1 (en) 1996-10-15 1997-10-15 Carriers containing an etherlipid/complementarily shape lipid combination and therapeutic uses thereof

Publications (1)

Publication Number Publication Date
BR9712329A true BR9712329A (pt) 1999-08-31

Family

ID=24896093

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9712329-3A BR9712329A (pt) 1996-10-15 1997-10-15 Veículos contendo um éter lipídio/combinação de lipídio formado complementarmente e os usos terapêuticos dos mesmos

Country Status (17)

Country Link
US (2) US5932242A (pt)
EP (1) EP0966266A4 (pt)
JP (1) JP2001502332A (pt)
KR (1) KR100512689B1 (pt)
CN (1) CN1088582C (pt)
AU (1) AU722092B2 (pt)
BR (1) BR9712329A (pt)
CA (1) CA2268841A1 (pt)
CZ (1) CZ131799A3 (pt)
HU (1) HUP0000523A3 (pt)
IL (1) IL129473A0 (pt)
NO (1) NO991770L (pt)
NZ (1) NZ335125A (pt)
PL (1) PL190711B1 (pt)
SK (1) SK283817B6 (pt)
TR (1) TR199900799T2 (pt)
WO (1) WO1998016200A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667053B1 (en) 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
DE19829448A1 (de) * 1998-07-01 2000-10-12 Medmark Pharma Gmbh 1-Octadecyl-2-methyl-sn-glycero-3-phosphocholin (ET180CH3) zur Behandlung von humanen Mammakarzinomen
EP1587518A4 (en) * 2003-01-09 2008-08-20 Zeneus Pharma Ltd ANTINEOPLASTIC LIPIDIC ETHER COMPOUNDS HAVING MODIFICATIONS AT THE CARBON GROUP SN-3
EP1583552A2 (en) * 2003-01-09 2005-10-12 Zeneus Pharma Limited Antineoplastic ether lipid compounds
WO2004065719A2 (en) * 2003-01-16 2004-08-05 Hunter Douglas Inc. Covering for architectural surfaces and method of forming and applying same
MY143225A (en) 2004-04-02 2011-03-31 Osi Pharm Inc 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors
CA2584537C (en) 2004-10-19 2013-09-24 Hansjorg Eibl Formulations containing alkylphosphocholines using novel negative charge carriers
JP5382974B2 (ja) * 2005-03-11 2014-01-08 太陽化学株式会社 化粧料用組成物及び化粧料
KR100829595B1 (ko) 2006-12-11 2008-05-14 한국화학연구원 당이 결합된 인지질로 수식된 리포솜 및 이의 제조방법
EP2536414B1 (en) 2010-02-18 2016-07-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for preventing cancer metastasis
JP6963616B2 (ja) * 2016-12-14 2021-11-10 ベイジン ショウバイ ファーマシューティカル カンパニー，リミティッド ４級アンモニウム塩構造を有する二官能性化合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2009343C3 (de) * 1970-02-27 1980-10-23 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Verwendung von Lysolecithinen als immunologische Adjuvantien
GB2046092B (en) * 1979-03-05 1983-11-02 Toyama Chemical Co Ltd Pharmaceutical composition containing a lysophospholid and a phospholipid
JPS5772914A (en) * 1980-10-22 1982-05-07 Takeda Chem Ind Ltd Antitumor agent
DE3239858A1 (de) * 1982-07-06 1984-01-12 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Neue d-mannitderivate als ausgangsprodukte zur synthese von phospholipiden
US5169637A (en) * 1983-03-24 1992-12-08 The Liposome Company, Inc. Stable plurilamellar vesicles
US4983397A (en) * 1985-08-19 1991-01-08 Board Of Regents, University Of Texas System Pharmaceutical compositions consisting of acylated phospholipids
US5260284A (en) * 1987-02-17 1993-11-09 Board Of Regents, The University Of Texas System Methods employing unique mixtures of polar and neutral lipids and sterol for lung surfactant replacement therapy
US4965391A (en) * 1987-10-23 1990-10-23 The University Of Michigan Radioiodinated phospholipid ether analogues
US5077057A (en) * 1989-04-05 1991-12-31 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
DE4132345A1 (de) * 1991-09-27 1993-04-01 Max Planck Gesellschaft Ether-lysolecithine und alkylphosphocholine in liposomen
DE69519802T2 (de) * 1994-10-14 2001-04-19 The Liposome Co.,Inc. Etherlipid-liposomen und deren therapeutische verwendung

Also Published As

Publication number Publication date
EP0966266A1 (en) 1999-12-29
CN1088582C (zh) 2002-08-07
WO1998016200A1 (en) 1998-04-23
NO991770L (no) 1999-06-09
IL129473A0 (en) 2000-02-29
EP0966266A4 (en) 2006-01-11
KR100512689B1 (ko) 2005-09-07
CN1240348A (zh) 2000-01-05
JP2001502332A (ja) 2001-02-20
SK49399A3 (en) 1999-11-08
AU4756797A (en) 1998-05-11
KR20000049128A (ko) 2000-07-25
SK283817B6 (sk) 2004-02-03
CA2268841A1 (en) 1998-04-23
US5932242A (en) 1999-08-03
HUP0000523A2 (hu) 2000-09-28
PL190711B1 (pl) 2005-12-30
NZ335125A (en) 1999-11-29
TR199900799T2 (xx) 1999-07-21
AU722092B2 (en) 2000-07-20
NO991770D0 (no) 1999-04-14
HUP0000523A3 (en) 2000-10-30
US6017557A (en) 2000-01-25
PL332696A1 (en) 1999-09-27
CZ131799A3 (cs) 1999-08-11
HK1024638A1 (en) 2000-10-20

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 36 DA LPI .