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DK1345620T3 - Stabiliseret sammensætning til sårdebridering - Google Patents

Stabiliseret sammensætning til sårdebridering

Info

Publication number
DK1345620T3
DK1345620T3 DK01962345T DK01962345T DK1345620T3 DK 1345620 T3 DK1345620 T3 DK 1345620T3 DK 01962345 T DK01962345 T DK 01962345T DK 01962345 T DK01962345 T DK 01962345T DK 1345620 T3 DK1345620 T3 DK 1345620T3
Authority
DK
Denmark
Prior art keywords
stabilized composition
wound debridement
wound
anhydrous hydrophilic
debridement
Prior art date
Application number
DK01962345T
Other languages
Danish (da)
English (en)
Inventor
David W Hobson
David P Jones
Katarzyna Koster
Pilar P Duque
Original Assignee
Healthpoint Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Healthpoint Ltd filed Critical Healthpoint Ltd
Application granted granted Critical
Publication of DK1345620T3 publication Critical patent/DK1345620T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Enzymes And Modification Thereof (AREA)
DK01962345T 2000-12-27 2001-08-06 Stabiliseret sammensætning til sårdebridering DK1345620T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/749,217 US6548556B2 (en) 2000-12-27 2000-12-27 Stable enzymatic wound debrider
PCT/US2001/041558 WO2002051436A2 (fr) 2000-12-27 2001-08-06 Composition de parage enzymatique stable pour des blessures

Publications (1)

Publication Number Publication Date
DK1345620T3 true DK1345620T3 (da) 2008-05-13

Family

ID=25012779

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01962345T DK1345620T3 (da) 2000-12-27 2001-08-06 Stabiliseret sammensætning til sårdebridering

Country Status (13)

Country Link
US (1) US6548556B2 (fr)
EP (1) EP1345620B1 (fr)
JP (1) JP4071628B2 (fr)
CN (1) CN1230200C (fr)
AT (1) ATE381941T1 (fr)
AU (1) AU2001283537B2 (fr)
CA (1) CA2433080C (fr)
DE (1) DE60132113T2 (fr)
DK (1) DK1345620T3 (fr)
ES (1) ES2296788T3 (fr)
MX (1) MXPA03005851A (fr)
PT (1) PT1345620E (fr)
WO (1) WO2002051436A2 (fr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632429B1 (en) 1999-12-17 2003-10-14 Joan M. Fallon Methods for treating pervasive development disorders
US8030002B2 (en) 2000-11-16 2011-10-04 Curemark Llc Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions
US20030099693A1 (en) * 2001-11-02 2003-05-29 Auffret Anthony David Wafer
US20030198631A1 (en) * 2002-04-18 2003-10-23 Healthpoint, Ltd. Thermolysin enzymatic wound debrider
US7785584B2 (en) * 2003-08-13 2010-08-31 Healthpoint, Ltd. Ointment wound spray
EP1673112A1 (fr) * 2003-10-10 2006-06-28 Coloplast A/S Pansement contenant des enzymes proteolytiques
US20050079147A1 (en) * 2003-10-14 2005-04-14 Bernard Delaey Wound healing compositions and uses
US20060182705A1 (en) * 2005-02-11 2006-08-17 Cruse Maria K Composition for reduction and prevention of wrinkles on the skin
US20080058282A1 (en) 2005-08-30 2008-03-06 Fallon Joan M Use of lactulose in the treatment of autism
FR2892949B1 (fr) * 2005-11-08 2008-05-16 Maco Pharma Sa Unite de filtration des leucocytes a adhesion des plaquettes reduites
US20070212342A1 (en) * 2005-12-20 2007-09-13 Swiss-American Products, Inc. Protease compositions for the treatment of damaged tissue
GB0606921D0 (en) * 2006-04-06 2006-05-17 Insense Ltd Skin dressing
US8754045B2 (en) * 2006-05-12 2014-06-17 James A. Livingston Enzymatic debridement therapy for abnormal cell proliferation
US8658163B2 (en) 2008-03-13 2014-02-25 Curemark Llc Compositions and use thereof for treating symptoms of preeclampsia
US8084025B2 (en) 2008-04-18 2011-12-27 Curemark Llc Method for the treatment of the symptoms of drug and alcohol addiction
US9320780B2 (en) 2008-06-26 2016-04-26 Curemark Llc Methods and compositions for the treatment of symptoms of Williams Syndrome
US11016104B2 (en) 2008-07-01 2021-05-25 Curemark, Llc Methods and compositions for the treatment of symptoms of neurological and mental health disorders
US10776453B2 (en) 2008-08-04 2020-09-15 Galenagen, Llc Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain
US20100092447A1 (en) 2008-10-03 2010-04-15 Fallon Joan M Methods and compositions for the treatment of symptoms of prion diseases
BRPI1007378A2 (pt) 2009-01-06 2020-08-18 Curemark Llc composições e métodos para o tratamento ou prevenção de infecções por staphylococcus aureus e para a erradicação ou redução de staphylococcus aureus sobre superfícies.
CA2747703C (fr) 2009-01-06 2021-06-15 Curemark Llc Compositions et methodes de traitement ou de prevention d'infections par e. coli
EP2226382A1 (fr) 2009-03-03 2010-09-08 B.R.A.I.N. Biotechnology Research and Information Network AG Protéase pour le conditionnement des blessures et soin de la peau
US9056050B2 (en) 2009-04-13 2015-06-16 Curemark Llc Enzyme delivery systems and methods of preparation and use
WO2011050135A1 (fr) 2009-10-21 2011-04-28 Curemark Llc Méthodes et compositions utilisées pour prévenir et traiter la grippe
MX2012006661A (es) 2009-12-08 2012-11-12 Healthpoint Ltd Composiciones enzimaticas de desbridamiento de heridas con actividad enzimatica mejorada.
ES2659821T3 (es) 2010-06-08 2018-03-19 Buckman Laboratories International, Inc Métodos para degradar el lodo procedente de la pasta y la fabricación de papel
EP2701733B1 (fr) 2011-04-21 2019-04-03 Curemark, LLC Composés destinés au traitement de troubles neuropsychiatriques
RU2013150536A (ru) 2011-05-12 2015-06-20 Смит & Невью Ортопедикс АГ Способ и топическая композиция для обработки ран, содержащая seaprose и его применение
CA2862363C (fr) * 2012-02-02 2021-06-08 Joan M. Fallon Compositions enzymatiques et leur utilisation pour la cicatrisation
RU2014145270A (ru) 2012-05-11 2016-07-10 Смит & Невью, Инк. Способ и композиция для разрушения бактериальной биопленки
US10350278B2 (en) 2012-05-30 2019-07-16 Curemark, Llc Methods of treating Celiac disease
AU2013344659B2 (en) 2012-11-14 2017-10-05 Smith & Nephew, Inc. Stable thermolysin hydrogel
EP2968645B1 (fr) 2013-03-15 2020-02-26 Smith & Nephew, Inc. Film soluble formant un gel servant à délivrer des agents actifs
WO2015074159A1 (fr) 2013-11-25 2015-05-28 Dermal Devices Inc. Composition, système, et méthode pour le traitement de la peau
US10238719B2 (en) 2014-10-10 2019-03-26 Rochal Industries, Llc Compositions and kits for enzymatic debridement and methods of using the same
US20160101166A1 (en) 2014-10-10 2016-04-14 Rochal Industries, Llp Compositions and kits for treating pruritus and methods of using the same
US9592280B2 (en) 2014-10-10 2017-03-14 Rochal Industries Llc Compositions and kits for enzymatic debridement and methods of using the same
US11938173B2 (en) 2014-12-12 2024-03-26 Smith & Nephew, Inc. Use of Clostridium histolyticum protease mixture in promoting wound healing
CN105255825B (zh) * 2015-11-16 2019-07-19 广州赛莱拉干细胞科技股份有限公司 一种跟腱来源肌腱干细胞原代分离消化液及分离方法
KR102376345B1 (ko) 2016-01-31 2022-03-18 메디운드 리미티드 상처 치료용 괴사조직제거 조성물
CN109475608A (zh) 2016-04-18 2019-03-15 麦迪伍德有限公司 慢性伤口清创的方法
WO2018020435A1 (fr) 2016-07-27 2018-02-01 Smith & Nephew, Inc. Utilisation de la thermolysine pour réduire ou éliminer les biofilms bactériens sur des surfaces
WO2018140707A1 (fr) 2017-01-30 2018-08-02 Smith & Nephew, Inc. Combinaison synergique de thermolysine et d'un agent antibactérien pour réduire ou éliminer les biofilms bactériens de surfaces
CN106902075A (zh) * 2017-02-23 2017-06-30 任君刚 一种基于无水技术的水敏感粘附性软膏及其制备方法
US12226464B2 (en) 2017-04-10 2025-02-18 Curemark, Llc Compositions for treating addiction
CN110180019A (zh) * 2019-07-11 2019-08-30 周玉芳 一种提高皮肤修复功能的复合酶及其制备方法
US11541009B2 (en) 2020-09-10 2023-01-03 Curemark, Llc Methods of prophylaxis of coronavirus infection and treatment of coronaviruses

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2917433A (en) 1956-04-02 1959-12-15 Rystan Company Stable aqueous papain topical compositions
US2995493A (en) 1957-04-17 1961-08-08 Johnson & Johnson Ficus enzyme and hydrophilic carrier composition
US3019171A (en) 1957-11-25 1962-01-30 Ethicon Inc Activated enzyme compositions
US3003917A (en) 1959-01-14 1961-10-10 Nat Drug Co Wound healing composition
US3409719A (en) 1967-05-23 1968-11-05 Baxter Laboratories Inc Debridement agent
US3860702A (en) 1972-07-11 1975-01-14 Schuyler Dev Corp Anti-inflammatory compositions
US3983209A (en) 1975-01-28 1976-09-28 Alza Corporation Method for treating burns
GB1594389A (en) 1977-06-03 1981-07-30 Max Planck Gesellschaft Dressing material for wounds
US4250167A (en) 1978-09-19 1981-02-10 Davis Elgan A Methods for reducing calcium deposits
EP0107634B1 (fr) 1982-10-25 1989-04-12 Lars Gustav Inge Hellgren Composition d'enzyme pour le nettoyage, son utilisation et préparation de la composition
SE8302268L (sv) 1983-04-22 1984-10-23 Lars G I Hellgren Ny kombination av proteolytiska och lipolytiska enzymer lemplig som tvettkomposition
US4668228A (en) * 1985-03-12 1987-05-26 Johnson & Johnson Products, Inc. Debriding tape
GB8724728D0 (en) 1987-10-22 1987-11-25 Genzyme Corp Cysteine proteinase
US5206026A (en) 1988-05-24 1993-04-27 Sharik Clyde L Instantaneous delivery film
US5296222A (en) 1989-02-23 1994-03-22 University Of Utah Percutaneous drug delivery system
US5130131A (en) 1989-08-18 1992-07-14 University Of Florida Methods for the control of fungi and bacteria
EP0498532A1 (fr) 1991-01-10 1992-08-12 E.R. SQUIBB & SONS, INC. Poudre pour le débridement des tissus nécropés contenant une enzyme protéolytique
JPH07508975A (ja) 1992-04-23 1995-10-05 バーレックス　ラボラトリーズ　インコーポレイテッド 生体接着性水性鉱油エマルション軟膏基剤，それからなる局所医薬組成物及び創傷治癒におけるその使用
US6030612A (en) 1994-11-22 2000-02-29 Phairson Medical Inc. Antimicrobial uses of multifunctional enzyme
IL105699A0 (en) 1992-06-26 1993-09-22 Genzyme Corp Hydrophilic creams for delivery of therapeutic agents
AU1939895A (en) 1994-03-01 1995-09-18 E.R. Squibb & Sons, Inc. Enzymatic debridement compositions and methods
US5387517A (en) 1994-03-23 1995-02-07 Ethicon, Inc. Thiol activated protease from stem bromelain for treating devitalized tissue
US5505958A (en) 1994-10-31 1996-04-09 Algos Pharmaceutical Corporation Transdermal drug delivery device and method for its manufacture
US5494896A (en) 1995-03-31 1996-02-27 Xoma Corporation Method of treating conditions associated with burn injuries
US5747005A (en) * 1995-08-02 1998-05-05 Barels; Ronald R. Oil-based, anti-plaque dentifrice composition
CA2231769A1 (fr) 1995-09-14 1997-03-20 James L. Sorenson Composition et procede pour traiter les ongles malades
US6017531A (en) 1997-06-02 2000-01-25 W. R. Grace & Co. Hydrophilic composition containing protease produced by Vibrio
CA2295247C (fr) 1997-06-18 2009-05-26 Cohesion Technologies, Inc. Compositions contenant de la thrombine et du collagene microfibrillaire

Also Published As

Publication number Publication date
HK1056834A1 (en) 2004-03-05
EP1345620B1 (fr) 2007-12-26
JP2004520321A (ja) 2004-07-08
ES2296788T3 (es) 2008-05-01
DE60132113T2 (de) 2008-12-18
PT1345620E (pt) 2008-01-10
CN1494431A (zh) 2004-05-05
CA2433080C (fr) 2004-07-06
MXPA03005851A (es) 2004-05-04
AU2001283537B2 (en) 2005-04-14
DE60132113D1 (de) 2008-02-07
WO2002051436A3 (fr) 2002-10-03
US20020114798A1 (en) 2002-08-22
CN1230200C (zh) 2005-12-07
US6548556B2 (en) 2003-04-15
WO2002051436A2 (fr) 2002-07-04
ATE381941T1 (de) 2008-01-15
EP1345620A2 (fr) 2003-09-24
JP4071628B2 (ja) 2008-04-02
CA2433080A1 (fr) 2002-07-04

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