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DK1222180T3 - Enantiomere forbindelser til behandling af hjertearytmier og fremgangsmåde til anvendelse - Google Patents

Enantiomere forbindelser til behandling af hjertearytmier og fremgangsmåde til anvendelse

Info

Publication number
DK1222180T3
DK1222180T3 DK00972216T DK00972216T DK1222180T3 DK 1222180 T3 DK1222180 T3 DK 1222180T3 DK 00972216 T DK00972216 T DK 00972216T DK 00972216 T DK00972216 T DK 00972216T DK 1222180 T3 DK1222180 T3 DK 1222180T3
Authority
DK
Denmark
Prior art keywords
compounds
treatment
cardiac arrhythmias
methods
enantiomeric compounds
Prior art date
Application number
DK00972216T
Other languages
English (en)
Inventor
Pascal Druzgala
Peter G Milner
Original Assignee
Aryx Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/680,873 external-priority patent/US6372783B1/en
Application filed by Aryx Therapeutics filed Critical Aryx Therapeutics
Application granted granted Critical
Publication of DK1222180T3 publication Critical patent/DK1222180T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK00972216T 1999-10-15 2000-10-13 Enantiomere forbindelser til behandling af hjertearytmier og fremgangsmåde til anvendelse DK1222180T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15960999P 1999-10-15 1999-10-15
US09/680,873 US6372783B1 (en) 1999-10-15 2000-10-06 Enantiomeric compounds for treatment of cardiac arrhythmias and methods of use
US09/684,046 US6362223B1 (en) 1999-10-15 2000-10-06 Enantiomeric compounds for treatment of cardiac arrhythmias and methods of use
PCT/US2000/028636 WO2001029018A2 (en) 1999-10-15 2000-10-13 Novel enantiomeric compounds for treatment of cardiac arrhythmias and methods of use

Publications (1)

Publication Number Publication Date
DK1222180T3 true DK1222180T3 (da) 2007-12-27

Family

ID=27388333

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00972216T DK1222180T3 (da) 1999-10-15 2000-10-13 Enantiomere forbindelser til behandling af hjertearytmier og fremgangsmåde til anvendelse

Country Status (11)

Country Link
EP (1) EP1222180B1 (da)
JP (1) JP4684514B2 (da)
AT (1) ATE369351T1 (da)
AU (1) AU774873B2 (da)
CA (1) CA2392016C (da)
DE (1) DE60035888T2 (da)
DK (1) DK1222180T3 (da)
ES (1) ES2290054T3 (da)
HK (1) HK1049829B (da)
PT (1) PT1222180E (da)
WO (1) WO2001029018A2 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002038557A2 (en) * 1993-06-16 2002-05-16 Aryx Therapeutics Benzoylbenzofurane derivatives for treatment of cardiac arrhythmia
CA2425245A1 (en) * 2000-10-06 2002-05-16 Aryx Therapeutics Novel compounds for treatment of cardiac arrhythmia synthesis, and methods of use
DE10129119B4 (de) * 2001-06-16 2007-10-04 Schwarz Pharma Ag Kristalline Salze von Benzoylbenzofuran-Derivaten, insbesondere von[2-(4-{1-[2-((S)-sec.-Butoxycarbonylmethyl)-benzofuran-3-carbonyl]-methanoyl}-2,6-diiod-phenoxy)-ethyl]-diethylamino und [2-(4-{1-[(3-Methyl-2-(S)-Butoxycarbonylmethyl)-benzofuran-3-carbonyl]- methanoyl}-2,6-diiodphenoxy)-ethyl]-diethylamino, deren Verwendung und Herstellung sowie diese Salze enthaltende Arzneimittel
CA2560336A1 (en) 2004-04-09 2005-10-27 Aryx Therapeutics Benzofuranyl derivatives useful for the treatment of cardiac arrhythmia
PT1904502E (pt) 2005-07-15 2009-12-15 Aryx Therapeutics Inc Compostos precursores antiarrítmicos, processos de síntese e métodos de utilização
WO2010059119A1 (en) * 2008-11-21 2010-05-27 Astrazeneca Ab A combination of tert -butyl (2-{7- [2- (4-cyano-2- f luorophenoxy) ethyl] -9-oxa-3, 7-diazabicyclo [3.3.1] non-3- yl } ethyl) carbamate and certain antiarrhythmic benzofurans

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364880A (en) * 1993-06-16 1994-11-15 Advanced Therapies, Inc. Compound for treatment of cardiac arrhythmia, synthesis, and methods of use

Also Published As

Publication number Publication date
JP4684514B2 (ja) 2011-05-18
EP1222180A2 (en) 2002-07-17
DE60035888T2 (de) 2007-12-06
ATE369351T1 (de) 2007-08-15
CA2392016C (en) 2010-04-13
JP2003512364A (ja) 2003-04-02
PT1222180E (pt) 2007-09-20
AU1091201A (en) 2001-04-30
ES2290054T3 (es) 2008-02-16
WO2001029018A2 (en) 2001-04-26
AU774873B2 (en) 2004-07-08
HK1049829A1 (en) 2003-05-30
DE60035888D1 (de) 2007-09-20
EP1222180B1 (en) 2007-08-08
HK1049829B (en) 2008-02-22
CA2392016A1 (en) 2001-04-26
WO2001029018A3 (en) 2001-11-29

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