[go: up one dir, main page]

DK1297016T3 - Anvendelse af placentavækstfaktorinhibitorer til behandling af patologisk angiogenese, patologisk arteriogenese, inflammation, tumordannelse og/eller vaskulær lækage - Google Patents

Anvendelse af placentavækstfaktorinhibitorer til behandling af patologisk angiogenese, patologisk arteriogenese, inflammation, tumordannelse og/eller vaskulær lækage

Info

Publication number
DK1297016T3
DK1297016T3 DK01943357T DK01943357T DK1297016T3 DK 1297016 T3 DK1297016 T3 DK 1297016T3 DK 01943357 T DK01943357 T DK 01943357T DK 01943357 T DK01943357 T DK 01943357T DK 1297016 T3 DK1297016 T3 DK 1297016T3
Authority
DK
Denmark
Prior art keywords
growth factor
arteriogenesis
pathological
pigf
vascular leakage
Prior art date
Application number
DK01943357T
Other languages
Danish (da)
English (en)
Inventor
Peter Carmeliet
Desire Collen
Falco Sandro De
Ruvo Menotti
Original Assignee
Vlaams Interuniv Inst Biotech
D Collen Res Foundation Vzw
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8171493&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1297016(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vlaams Interuniv Inst Biotech, D Collen Res Foundation Vzw filed Critical Vlaams Interuniv Inst Biotech
Application granted granted Critical
Publication of DK1297016T3 publication Critical patent/DK1297016T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK01943357T 2000-05-12 2001-05-10 Anvendelse af placentavækstfaktorinhibitorer til behandling af patologisk angiogenese, patologisk arteriogenese, inflammation, tumordannelse og/eller vaskulær lækage DK1297016T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00201714 2000-05-12

Publications (1)

Publication Number Publication Date
DK1297016T3 true DK1297016T3 (da) 2006-07-10

Family

ID=8171493

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01943357T DK1297016T3 (da) 2000-05-12 2001-05-10 Anvendelse af placentavækstfaktorinhibitorer til behandling af patologisk angiogenese, patologisk arteriogenese, inflammation, tumordannelse og/eller vaskulær lækage

Country Status (10)

Country Link
US (8) US7482004B2 (fr)
EP (1) EP1297016B1 (fr)
AT (1) ATE321069T1 (fr)
AU (2) AU6595301A (fr)
CA (1) CA2407858C (fr)
DE (1) DE60118186T2 (fr)
DK (1) DK1297016T3 (fr)
ES (1) ES2260234T3 (fr)
PT (1) PT1297016E (fr)
WO (1) WO2001085796A2 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1297016E (pt) * 2000-05-12 2006-07-31 Vlaams Interuniv Inst Biotech Utilizacao de inibidores de factor de crescimento placentario para o tratamento da angiogenese patologica, da arteriogenese patologica, da inflamacao, da formacao de tumores e/ou das figas vasculares
WO2002011769A1 (fr) * 2000-08-04 2002-02-14 Human Genome Sciences, Inc. Facteur 2 de croissance endothéliale (vegf-2)
GB2374870A (en) * 2001-01-26 2002-10-30 Thromb X Nv Use of genetically modified multicellular animals in the identification of drug target proteins
US20050232921A1 (en) * 2001-04-13 2005-10-20 Rosen Craig A Vascular endothelial growth factor 2
CA2444624A1 (fr) * 2001-04-13 2002-10-24 Human Genome Sciences, Inc. Facteur de croissance endothelial vasculaire 2
EP2228389B1 (fr) * 2001-04-13 2015-07-08 Human Genome Sciences, Inc. Anticorps contre facteur de croissance endothéliale vasculaire 2
GB2384706A (en) * 2002-02-04 2003-08-06 Thromb X Nv Agent for the prevention or minimisation of post-operative adhesion formation and/or cell implantation
ITRM20020277A1 (it) * 2002-05-17 2003-11-17 Geymonat Spa Muteine del fattore di crescita placentare tipo 1, metodo di preparazione e loro applicazioni.
EP1517704A1 (fr) 2002-06-28 2005-03-30 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Utilisation d'anticorps contre flt-1 dans le traitement de l'osteoporose
ES2391313T3 (es) 2002-11-16 2012-11-23 Siemens Healthcare Diagnostics Products Gmbh SCD40L, PAPP-A y factor de crecimiento placentario (PIGF) como combinación de marcadores bioquímicos en enfermedades cardiovasculares
GB0228409D0 (en) * 2002-12-06 2003-01-08 Thromb X Nv Pharmacological vitreolysis
JP2007528355A (ja) * 2003-03-07 2007-10-11 アンジェスＭｇ株式会社 血管壁の炎症および新生内膜過形成を阻害する組成物および方法
ES2314444T3 (es) 2003-08-29 2009-03-16 Pfizer Inc. Tienopiridina-fenilacetaminasy sus derivados utiles como nuevos agentes antiangiogenicos.
JP4503022B2 (ja) 2003-12-23 2010-07-14 ファイザー・インク 新規キノリン誘導体
US20050282233A1 (en) * 2004-03-05 2005-12-22 Ludwig Institute For Cancer Research Multivalent antibody materials and methods for VEGF/PDGF family of growth factors
EP1812064A4 (fr) * 2004-11-19 2009-07-08 Cornell Res Foundation Inc Utilisation des cellules du recepteur du facteur de croissance endothelial vasculaire dans le traitement et la surveillance du cancer et dans le criblage d'agents chimiotherapeutiques
ES2384110T3 (es) 2005-03-24 2012-06-29 Thrombogenics N.V. Anticuerpo anti-PLGF novedoso
DE102005022047A1 (de) * 2005-05-09 2006-11-30 Dade Behring Marburg Gmbh Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung
US7867490B2 (en) 2005-06-30 2011-01-11 Vib Vzw Treatment of liver cirrhosis and its complications
CN101534865A (zh) * 2005-10-19 2009-09-16 Ibc药品公司 生物活性装配体的制备方法及其用途
CN100355882C (zh) * 2005-12-05 2007-12-19 中国人民解放军军事医学科学院放射与辐射医学研究所 杂交瘤细胞株及其产生的抗人vegfr－3的单克隆抗体
AU2007317753B2 (en) * 2006-11-09 2013-11-07 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Differential gene expression in physiological and pathological angiogenesis
AU2014200453B2 (en) * 2006-11-09 2015-06-18 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Differential gene expression in physiological and pathological angiogenesis
US8715743B2 (en) 2007-08-03 2014-05-06 Musc Foundation For Research Development Human monoclonal antibodies and methods for producing the same
WO2009089286A1 (fr) 2008-01-07 2009-07-16 Ortho-Clinical Diagnostics, Inc. Détermination d'un complexe sflt-1 : facteur angiogénique
WO2009117791A2 (fr) 2008-03-28 2009-10-01 Katholieke Universiteit Leuven Signatures génétiques des muqueuses
AU2009299744B2 (en) 2008-10-02 2015-08-20 Life Sciences Research Partners Vzw Inhibition of PLGF to treat Philadelphia chromosome positive leukemia
GB0914318D0 (en) 2009-08-14 2009-09-30 Medical Res Council Method
DE102010013555A1 (de) 2010-03-31 2011-10-06 Christian Hamm Verwendung der Biomarker sFlt und PIGF in der Diagnose und Therapie der pulmonalen Hypertonie
WO2012151574A1 (fr) 2011-05-05 2012-11-08 Duke University Procédés pour mettre au point un pronostic du cancer du pancréas et prédire la réponse à une thérapie contre le cancer
DK2785739T3 (en) 2011-12-01 2017-07-03 Thrombogenics Nv IMPROVING THE RESULT OF TREASURE CULECTOMY
KR102269650B1 (ko) 2012-04-20 2021-06-28 메뤼스 엔.페. Ig-유사 분자의 제조방법 및 제조수단
AU2017231765A1 (en) * 2016-03-10 2018-08-23 Oxurion NV Posterior ocular fibrosis inhibition by antagonizing placental growth factor
WO2017201166A1 (fr) * 2016-05-17 2017-11-23 Duke University Méthodes de prédiction de la réaction d'un cancer à un agent de ciblage du vegf et méthodes de pronostic et de traitement du cancer
US20200306283A1 (en) 2016-06-22 2020-10-01 William Warren HARLESS Cancer treatment and metastasis inhibition using an anti-cancer stem cell agent in combination with a neu1 sialidase inhibitor or a cytokine inhibitor after primary cancer treatment
CA3112169A1 (fr) * 2018-09-11 2020-03-19 Anbition S.R.L. Peptides et leurs utilisations medicales
CA3112175A1 (fr) * 2018-09-11 2020-03-19 Anbition S.R.L. Peptides et leurs utilisations medicales

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US5545806A (en) * 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
IT1242149B (it) * 1990-09-27 1994-02-16 Consiglio Nazionale Ricerche Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi
US20010021382A1 (en) * 1991-03-29 2001-09-13 Genentech, Inc. Vascular endothelial cell growth factor antagonists
EP0633945B1 (fr) * 1992-04-03 1998-12-30 Genentech, Inc. ANTICORPS DE L'INTEGRINE ALPHA v BETA 3
US6177401B1 (en) * 1992-11-13 2001-01-23 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
US5861499A (en) * 1994-02-10 1999-01-19 Imclone Systems Incorporated Nucleic acid molecules encoding the variable or hypervariable region of a monoclonal antibody that binds to an extracellular domain
US6846839B1 (en) * 1995-06-07 2005-01-25 Sugen, Inc. Methods for treating diseases and disorders related to unregulated angiogenesis and/or vasculogenesis
US6986890B1 (en) * 1996-11-21 2006-01-17 Kyowa Hakko Kogyo Co., Ltd. Anti-human VEGF receptor Flt-1 monoclonal antibody
GB9723780D0 (en) * 1997-11-12 1998-01-07 Univ Manchester Regulation of ocular angiogenesis
ATE405651T1 (de) * 1998-03-17 2008-09-15 Genentech Inc Zu vegf und bmp1 homologe polypeptide
EP1079688A1 (fr) 1998-05-26 2001-03-07 Innogenetics N.V. Procede permettant d'augmenter des lymphocytes b de primates chez la souris immunodeprimee, et de produire de grands nombres de lymphocytes b specifiques de l'antigene pour la production d'anticorps monoclonaux de primates
WO2001057067A1 (fr) * 2000-02-04 2001-08-09 Supratek Pharma Inc. Ligand du recepteur de facteur de croissance endothelial vasculaire
PT1297016E (pt) * 2000-05-12 2006-07-31 Vlaams Interuniv Inst Biotech Utilizacao de inibidores de factor de crescimento placentario para o tratamento da angiogenese patologica, da arteriogenese patologica, da inflamacao, da formacao de tumores e/ou das figas vasculares
EP1517704A1 (fr) * 2002-06-28 2005-03-30 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Utilisation d'anticorps contre flt-1 dans le traitement de l'osteoporose
ES2384110T3 (es) * 2005-03-24 2012-06-29 Thrombogenics N.V. Anticuerpo anti-PLGF novedoso
US7867490B2 (en) * 2005-06-30 2011-01-11 Vib Vzw Treatment of liver cirrhosis and its complications

Also Published As

Publication number Publication date
US20130177565A1 (en) 2013-07-11
US20090074765A1 (en) 2009-03-19
AU6595301A (en) 2001-11-20
US20130183310A1 (en) 2013-07-18
ES2260234T3 (es) 2006-11-01
CA2407858C (fr) 2015-10-27
WO2001085796A3 (fr) 2002-04-04
AU2001265953B2 (en) 2005-09-29
EP1297016B1 (fr) 2006-03-22
ATE321069T1 (de) 2006-04-15
DE60118186D1 (de) 2006-05-11
US20030180286A1 (en) 2003-09-25
DE60118186T2 (de) 2006-12-28
WO2001085796A2 (fr) 2001-11-15
EP1297016A2 (fr) 2003-04-02
US20130177564A1 (en) 2013-07-11
US20090162354A1 (en) 2009-06-25
US20120263710A1 (en) 2012-10-18
US7482004B2 (en) 2009-01-27
CA2407858A1 (fr) 2001-11-15
PT1297016E (pt) 2006-07-31
US20090238826A1 (en) 2009-09-24

Similar Documents

Publication Publication Date Title
DK1297016T3 (da) Anvendelse af placentavækstfaktorinhibitorer til behandling af patologisk angiogenese, patologisk arteriogenese, inflammation, tumordannelse og/eller vaskulær lækage
DE10346913A1 (de) Acylhydrazonderivate
ATE368662T1 (de) Piperidinyl-thiazol-carbonsäure-derivate als angiogenesis inhibitoren
SE9800836D0 (sv) New Compounds
DK1261368T3 (da) Tværbunden, ikke-fungal lipaseholdig sammensætning og fremgangsmåder til anvendelse deraf
DE60215089D1 (de) Ausrichtungsverfahren zur Optimierung des Extinktionsverhältnisses beschichteter Polarisationsstrahlteiler
DK3911648T3 (da) 6'-[[(1s,3s)-3-[[5-(difluormethoxy)-2-pyrimidinyl]amino]cyclopentyl]amino][1(2h),3'-bipyridin]-2-on som pcsk9-hæmmer og fremgangsmåder til anvendelse deraf
DK1425028T3 (da) Anvendelse af IL-18 inhibitorer til behandling eller forebyggelse af sepsis
NO20081755L (no) Modifiserte proteaser som inhiberer komplementaktivering
NO20031192D0 (no) Isoksazoler og deres anvendelse som inhibitorer av ERK
ATE196780T1 (de) Herstellungsverfahren von kornorientierter elektrostahlband mit hohe magnetische eigenschaften, ausgehend von dünnbrammen
DE50109164D1 (de) Therapeutische verwendung von extrakten aus sophora flavescens oder sophora subprostrata
WO2004059318A3 (fr) Techniques de detection d'inhibition de formation de fibroblastes, techniques et compositions permettant de renforcer la formation de fibroblastes
NO20044906L (no) Parasittkontroll hos dyr
EA200300834A1 (ru) Антагонисты фактора, высвобождающего кортикотропин
DK1202743T3 (da) Farmaceutiske og kosmetiske sammensætninger omfattende serinproteaser fra torsk og deres farmaceutiske og kosmetiske anvendelse
ATE491701T1 (de) Von pyrazol abgeleitete kinaseinhibitoren und deren verwendung
DK1411916T3 (da) Fremgangsmåder og materialer til behandling af testosteronmangel hos mænd
DK1401869T3 (da) Molekyler og fremgangsmåder til inhibering af udskillkelse af kim 1
NO20013241D0 (no) Celleadhesjonsinhiberende anti-inflammatoriske og immunundertrykkende forbindelser
NO20063300L (no) Fremgangsmater for behandling av akutt inflammasjon i dyr med p38 MAP kinaseinhibitorer
DK1109571T3 (da) Fremgangsmåde til behandling af saltafhængig hypertension
PL3972604T3 (pl) Inhibitor kinazy tyrozynowej brutona do zastosowania w leczeniu przewlekłej pokrzywki spontanicznej
TR200102448T2 (tr) COPD tedavisi için kontrollu salma formülasyonu.
WO2002083622A3 (fr) Nouveaux derives d'aminophenyle cetone