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DK1196148T3 - Proces til mikroindkapsling af vand-opløselige stoffer - Google Patents

Proces til mikroindkapsling af vand-opløselige stoffer

Info

Publication number
DK1196148T3
DK1196148T3 DK00915076T DK00915076T DK1196148T3 DK 1196148 T3 DK1196148 T3 DK 1196148T3 DK 00915076 T DK00915076 T DK 00915076T DK 00915076 T DK00915076 T DK 00915076T DK 1196148 T3 DK1196148 T3 DK 1196148T3
Authority
DK
Denmark
Prior art keywords
encapsulation
micro
water
soluble substances
present
Prior art date
Application number
DK00915076T
Other languages
English (en)
Inventor
Evelyne Vuaridel
Piero Orsolini
Original Assignee
Debio Rech Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debio Rech Pharma Sa filed Critical Debio Rech Pharma Sa
Application granted granted Critical
Publication of DK1196148T3 publication Critical patent/DK1196148T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK00915076T 1999-04-15 2000-04-14 Proces til mikroindkapsling af vand-opløselige stoffer DK1196148T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99107570A EP1044683A1 (en) 1999-04-15 1999-04-15 One-step dispersion method for the microencapsulation of water soluble substances
PCT/CH2000/000218 WO2000062761A1 (en) 1999-04-15 2000-04-14 Process for microencapsulation of water soluble substances

Publications (1)

Publication Number Publication Date
DK1196148T3 true DK1196148T3 (da) 2004-04-13

Family

ID=8237970

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00915076T DK1196148T3 (da) 1999-04-15 2000-04-14 Proces til mikroindkapsling af vand-opløselige stoffer

Country Status (11)

Country Link
US (1) US6777002B1 (da)
EP (2) EP1044683A1 (da)
JP (1) JP2002542184A (da)
AT (1) ATE256458T1 (da)
AU (1) AU779712B2 (da)
CA (1) CA2369808A1 (da)
DE (1) DE60007316T2 (da)
DK (1) DK1196148T3 (da)
ES (1) ES2213572T3 (da)
PT (1) PT1196148E (da)
WO (1) WO2000062761A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2431285A1 (en) * 2000-12-13 2002-06-20 Merckle Gmbh Microparticles with an improved release profile and method for the production thereof
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
WO2002058671A1 (en) * 2001-01-26 2002-08-01 Debio Recherche Pharmaceutique S.A. Burst free pharmaceutical microparticules
CA2435415A1 (en) * 2001-01-26 2002-08-01 Debio Recherche Pharmaceutique S.A. Microparticles of biodegradable polymer encapsulating a biologically active substance
EP1450766B1 (fr) * 2001-10-10 2015-04-22 Pierre Fabre Medicament Microspheres biodegradables a liberation prolongee et leur procede de preparation
CN102166192B (zh) 2003-04-10 2013-09-25 Pr药品有限公司 一种用于生产基于乳化的微观粒子的方法
CA2532302C (en) * 2003-07-15 2016-12-20 Pr Pharmaceuticals, Inc. Method for the preparation of controlled release formulations
JP5165240B2 (ja) 2003-07-23 2013-03-21 ピーアール ファーマシューティカルズ， インコーポレイテッド 徐放組成物
WO2006052712A1 (en) * 2004-11-08 2006-05-18 Baxter International Inc. Nanoparticulate compositions of tubulin inhibitor
US20060233849A1 (en) * 2005-04-13 2006-10-19 Simon Bruce J Composite bone graft material
US7621963B2 (en) * 2005-04-13 2009-11-24 Ebi, Llc Composite bone graft material
JP2007002197A (ja) * 2005-06-27 2007-01-11 Kuraray Co Ltd コーティング剤及びコーティング皮膜
GB0711007D0 (en) * 2007-06-07 2007-07-18 Isis Innovation Polymeric microparticles
EP2222281B1 (en) 2007-12-20 2018-12-05 Evonik Corporation Process for preparing microparticles having a low residual solvent volume
US8236350B2 (en) * 2008-08-01 2012-08-07 The Regents Of The University Of Michigan Polymer for tissue engineering applications and drug delivery
WO2010033776A1 (en) * 2008-09-18 2010-03-25 Surmodics Pharmaceuticals, Inc. Microencapsulation process with solvent and salt
EP2389160B1 (en) * 2009-01-23 2017-09-13 Evonik Corporation Continuous double emulsion process for making microparticles
US8927619B2 (en) 2011-12-21 2015-01-06 Jorg Thomas Wilken Color-stabilized iodopropynyl butylcarbamate
US9308172B2 (en) * 2012-10-26 2016-04-12 Board Of Trustees Of Michigan State University Device and method for encapsulation of hydrophilic materials
US12263252B2 (en) 2019-06-05 2025-04-01 The Florida International University Board Of Trustees Biotherapy for viral infections using biopolymer based micro/nanogels
US20200383932A1 (en) * 2019-06-05 2020-12-10 The Florida International University Board Of Trustees Biotherapy for viral infections using biopolymer based micro/nanogels

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE744162A (fr) * 1969-01-16 1970-06-15 Fuji Photo Film Co Ltd Procede d'encapsulage
DE2010116A1 (de) * 1970-03-04 1971-09-16 Farbenfabriken Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Mikrogranulaten
GB1413186A (en) * 1973-06-27 1975-11-12 Toyo Jozo Kk Process for encapsulation of medicaments
DK0471036T4 (da) * 1989-05-04 2004-07-19 Southern Res Inst Indkapslingsfremgangsmåde
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
US5238714A (en) * 1990-10-02 1993-08-24 Board Of Regents, The University Of Texas System Efficient microcapsule preparation and method of use
CH683149A5 (fr) * 1991-07-22 1994-01-31 Debio Rech Pharma Sa Procédé pour la préparation de microsphères en matériau polymère biodégradable.
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
US6090925A (en) * 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
EP2275089A1 (en) * 1993-11-19 2011-01-19 Alkermes Controlled Therapeutics, Inc. Preparation of biodegradable microparticles containing a biologically active agent
KR0162872B1 (ko) * 1996-04-01 1998-12-01 김은영 용매추출법을 이용한 생분해성 고분자 미립구의 개선된 제조방법 및 이를 이용한 국소염증 질환 치료용 미립구의 제조방법
US5792477A (en) * 1996-05-07 1998-08-11 Alkermes Controlled Therapeutics, Inc. Ii Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent

Also Published As

Publication number Publication date
EP1196148B1 (en) 2003-12-17
AU3651800A (en) 2000-11-02
ES2213572T3 (es) 2004-09-01
AU779712B2 (en) 2005-02-10
ATE256458T1 (de) 2004-01-15
EP1044683A1 (en) 2000-10-18
EP1196148A1 (en) 2002-04-17
PT1196148E (pt) 2004-05-31
JP2002542184A (ja) 2002-12-10
WO2000062761A1 (en) 2000-10-26
DE60007316T2 (de) 2004-09-30
CA2369808A1 (en) 2000-10-26
US6777002B1 (en) 2004-08-17
DE60007316D1 (de) 2004-01-29

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