DK1180519T3 - Hydrochlorid af en kondenseret heterocyklisk forbindelse - Google Patents
Hydrochlorid af en kondenseret heterocyklisk forbindelseInfo
- Publication number
- DK1180519T3 DK1180519T3 DK00931547T DK00931547T DK1180519T3 DK 1180519 T3 DK1180519 T3 DK 1180519T3 DK 00931547 T DK00931547 T DK 00931547T DK 00931547 T DK00931547 T DK 00931547T DK 1180519 T3 DK1180519 T3 DK 1180519T3
- Authority
- DK
- Denmark
- Prior art keywords
- hydrochloride
- heterocyclic compound
- condensed heterocyclic
- compound
- benzylüthiazolid
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002218 hypoglycaemic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14351399 | 1999-05-24 | ||
| PCT/JP2000/003325 WO2000071540A1 (fr) | 1999-05-24 | 2000-05-24 | Chlorhydrate de compose heterocyclique fusionne |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1180519T3 true DK1180519T3 (da) | 2005-06-13 |
Family
ID=15340495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00931547T DK1180519T3 (da) | 1999-05-24 | 2000-05-24 | Hydrochlorid af en kondenseret heterocyklisk forbindelse |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6706746B2 (fr) |
| EP (1) | EP1180519B1 (fr) |
| KR (2) | KR100748053B1 (fr) |
| CN (1) | CN1156473C (fr) |
| AT (1) | ATE294799T1 (fr) |
| AU (1) | AU763731B2 (fr) |
| BR (1) | BR0010914A (fr) |
| CA (1) | CA2375017C (fr) |
| CZ (1) | CZ297927B6 (fr) |
| DE (1) | DE60019919T2 (fr) |
| DK (1) | DK1180519T3 (fr) |
| ES (1) | ES2240099T3 (fr) |
| HK (1) | HK1042087B (fr) |
| HU (1) | HU229340B1 (fr) |
| IL (1) | IL146568A0 (fr) |
| MX (1) | MXPA01012044A (fr) |
| NO (1) | NO321578B1 (fr) |
| NZ (1) | NZ515570A (fr) |
| PL (1) | PL209389B1 (fr) |
| PT (1) | PT1180519E (fr) |
| RU (1) | RU2214410C2 (fr) |
| TR (1) | TR200103353T2 (fr) |
| TW (1) | TWI284533B (fr) |
| WO (1) | WO2000071540A1 (fr) |
| ZA (1) | ZA200109576B (fr) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI284533B (en) * | 1999-05-24 | 2007-08-01 | Sankyo Co | Pharmaceutical composition for treating hyperglycemia, impaired glucose tolerance, diabetes complications and for improving insulin resistant |
| WO2002051441A1 (fr) | 2000-12-26 | 2002-07-04 | Sankyo Company, Limited | Compositions medicinales contenant un diuretique et un agent renforçant la resistance a l'insuline |
| US6756399B2 (en) * | 2001-06-29 | 2004-06-29 | The United States Of America As Represented By The Department Of Health And Human Services | Use of lipoxygenase inhibitors and PPAR ligands as anti-cancer therapeutic and intervention agents |
| AU2003220855A1 (en) * | 2002-04-01 | 2003-10-13 | Sankyo Company, Limited | Medicinal antitumor composition |
| TW200408628A (en) * | 2002-08-02 | 2004-06-01 | Sankyo Co | Resorcinol and its derivatives |
| US7781464B2 (en) * | 2003-01-17 | 2010-08-24 | Bexel Pharmaceuticals, Inc. | Heterocyclic diphenyl ethers |
| US6794401B2 (en) * | 2003-01-17 | 2004-09-21 | Bexel Pharmaceuticals, Inc. | Amino acid phenoxy ethers |
| US7521465B2 (en) * | 2003-01-17 | 2009-04-21 | Bexel Pharmaceuticals, Inc. | Diphenyl ether derivatives |
| WO2004106542A1 (fr) | 2003-05-29 | 2004-12-09 | Sankyo Company, Limited | Compose resistant a l'insuline et methode de criblage de celui-ci |
| US7087576B2 (en) * | 2003-10-07 | 2006-08-08 | Bexel Pharmaceuticals, Inc. | Dipeptide phenyl ethers |
| SI1679074T1 (sl) * | 2003-10-24 | 2011-04-29 | Santen Pharmaceutical Co Ltd | Terapevtsko sredstvo za keratokonjuktivno motnjo |
| EP1566202A1 (fr) * | 2004-02-23 | 2005-08-24 | Sahltech I Göteborg AB | Utilisation d'agonistes de la resistine pour le traitement de l'arthrite rheumatoide |
| KR20070011329A (ko) * | 2004-03-29 | 2007-01-24 | 상꾜 가부시키가이샤 | 인슐린 저항성 개선제를 함유하는 당뇨병 치료제 |
| TW200608967A (en) | 2004-07-29 | 2006-03-16 | Sankyo Co | Pharmaceutical compositions containing with diabetic agent |
| CN101119748A (zh) * | 2004-12-13 | 2008-02-06 | 第一三共株式会社 | 用于治疗糖尿病的药物组合物 |
| TW200633702A (en) * | 2004-12-15 | 2006-10-01 | Sankyo Co | Medicinal composition containing fbpase inhibitor |
| TW200637856A (en) * | 2005-01-24 | 2006-11-01 | Sankyo Co | Process for producing thiazolidinedion compound and intermediate thereof |
| US20090227493A1 (en) * | 2005-05-27 | 2009-09-10 | Daiichi Sankyo Company, Limited | Combined drug for treating diabetes |
| JPWO2007007656A1 (ja) * | 2005-07-08 | 2009-01-29 | 第一三共株式会社 | チアゾリジンジオン化合物を含有する医薬組成物 |
| TW200738266A (en) * | 2005-09-29 | 2007-10-16 | Sankyo Co | Pharmaceutical agent containing insulin resistance improving agent |
| US8148389B2 (en) | 2005-11-28 | 2012-04-03 | Senju Pharmaceutical Co., Ltd. | Pharmaceutical comprising PPAR agonist |
| TW201336497A (zh) * | 2007-02-08 | 2013-09-16 | Daiichi Sankyo Co Ltd | 噻唑啶二酮化合物之結晶型及其製法 |
| AU2008239179B2 (en) * | 2007-04-05 | 2011-02-24 | Daiichi Sankyo Company, Limited | Fused bicyclic heteroaryl derivatives |
| WO2008143254A1 (fr) | 2007-05-21 | 2008-11-27 | Senju Pharmaceutical Co., Ltd. | Produit pharmaceutique contenant un agoniste de pparδ |
| US8722710B2 (en) | 2007-09-26 | 2014-05-13 | Deuterx, Llc | Deuterium-enriched pioglitazone |
| CN102341386A (zh) | 2009-03-05 | 2012-02-01 | 第一三共株式会社 | 吡啶衍生物 |
| AU2014236510A1 (en) | 2013-03-14 | 2015-09-24 | Deuterx, Llc | Deuterium-enriched 2,4-thiazolidinediones and methods of treatment |
| US10188639B2 (en) | 2014-01-15 | 2019-01-29 | Deuterx, Llc | Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone |
| US11319313B2 (en) | 2020-06-30 | 2022-05-03 | Poxel Sa | Crystalline forms of deuterium-enriched pioglitazone |
| US11767317B1 (en) | 2020-06-30 | 2023-09-26 | Poxel Sa | Methods of synthesizing enantiopure deuterium-enriched pioglitazone |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5143930A (en) * | 1990-02-07 | 1992-09-01 | Sankyo Company, Limited | Thiazolidine derivatives with anti-diabetic activity, their preparation and their use |
| CZ293016B6 (cs) * | 1995-06-01 | 2004-01-14 | Sankyo Company Limited | Benzimidazolové deriváty a farmaceutické prostředky s jejich obsahem |
| NZ286920A (en) | 1995-07-03 | 1997-06-24 | Sankyo Co | Use of combination of hmg-coa reductase inhibitors and of insulin sensitizers for the prevention/treatment of arteriosclerosis or xanthoma |
| TWI284533B (en) * | 1999-05-24 | 2007-08-01 | Sankyo Co | Pharmaceutical composition for treating hyperglycemia, impaired glucose tolerance, diabetes complications and for improving insulin resistant |
| AU760917B2 (en) * | 1999-07-19 | 2003-05-22 | Sankyo Company Limited | Preventive and therapeutic agents for cancer |
-
2000
- 2000-05-23 TW TW089109943A patent/TWI284533B/zh not_active IP Right Cessation
- 2000-05-24 WO PCT/JP2000/003325 patent/WO2000071540A1/fr not_active Ceased
- 2000-05-24 NZ NZ515570A patent/NZ515570A/en not_active IP Right Cessation
- 2000-05-24 TR TR2001/03353T patent/TR200103353T2/xx unknown
- 2000-05-24 RU RU2001131722/04A patent/RU2214410C2/ru not_active IP Right Cessation
- 2000-05-24 DK DK00931547T patent/DK1180519T3/da active
- 2000-05-24 AU AU49487/00A patent/AU763731B2/en not_active Ceased
- 2000-05-24 BR BR0010914-2A patent/BR0010914A/pt not_active Application Discontinuation
- 2000-05-24 DE DE60019919T patent/DE60019919T2/de not_active Expired - Lifetime
- 2000-05-24 KR KR1020017014773A patent/KR100748053B1/ko not_active Expired - Fee Related
- 2000-05-24 ES ES00931547T patent/ES2240099T3/es not_active Expired - Lifetime
- 2000-05-24 AT AT00931547T patent/ATE294799T1/de active
- 2000-05-24 CZ CZ20014182A patent/CZ297927B6/cs not_active IP Right Cessation
- 2000-05-24 PL PL351650A patent/PL209389B1/pl not_active IP Right Cessation
- 2000-05-24 KR KR1020077003629A patent/KR100783348B1/ko not_active Expired - Fee Related
- 2000-05-24 CA CA002375017A patent/CA2375017C/fr not_active Expired - Fee Related
- 2000-05-24 CN CNB008107831A patent/CN1156473C/zh not_active Expired - Fee Related
- 2000-05-24 HK HK02103877.0A patent/HK1042087B/en not_active IP Right Cessation
- 2000-05-24 HU HU0201334A patent/HU229340B1/hu not_active IP Right Cessation
- 2000-05-24 IL IL14656800A patent/IL146568A0/xx not_active IP Right Cessation
- 2000-05-24 EP EP00931547A patent/EP1180519B1/fr not_active Expired - Lifetime
- 2000-05-24 MX MXPA01012044A patent/MXPA01012044A/es active IP Right Grant
- 2000-05-24 PT PT00931547T patent/PT1180519E/pt unknown
-
2001
- 2001-11-20 ZA ZA200109576A patent/ZA200109576B/en unknown
- 2001-11-21 US US09/991,100 patent/US6706746B2/en not_active Expired - Fee Related
- 2001-11-23 NO NO20015712A patent/NO321578B1/no not_active IP Right Cessation
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