DK1144586T3 - Fremgangsmåde, beholder og indretning til overvågning af stofskifteaktiviteten i cellekulturer i flydende medier - Google Patents
Fremgangsmåde, beholder og indretning til overvågning af stofskifteaktiviteten i cellekulturer i flydende medierInfo
- Publication number
- DK1144586T3 DK1144586T3 DK00903502T DK00903502T DK1144586T3 DK 1144586 T3 DK1144586 T3 DK 1144586T3 DK 00903502 T DK00903502 T DK 00903502T DK 00903502 T DK00903502 T DK 00903502T DK 1144586 T3 DK1144586 T3 DK 1144586T3
- Authority
- DK
- Denmark
- Prior art keywords
- metabolic activity
- cells
- liquid medium
- oxygen
- liquid media
- Prior art date
Links
- 239000007788 liquid Substances 0.000 title abstract 5
- 230000002503 metabolic effect Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000012544 monitoring process Methods 0.000 title abstract 3
- 238000004113 cell culture Methods 0.000 title 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 5
- 229910052760 oxygen Inorganic materials 0.000 abstract 5
- 239000001301 oxygen Substances 0.000 abstract 5
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 230000036284 oxygen consumption Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19903506A DE19903506C2 (de) | 1999-01-29 | 1999-01-29 | Verfahren, Gefäß und Vorrichtung zur Überwachung der Stoffwechselaktivität von Zellkulturen in flüssigen Medien |
| PCT/DE2000/000071 WO2000044876A2 (fr) | 1999-01-29 | 2000-01-05 | Procede, recipient et dispositif pour la surveillance de l'activite metabolique de cultures cellulaires dans des milieux liquides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1144586T3 true DK1144586T3 (da) | 2002-12-30 |
Family
ID=7895759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00903502T DK1144586T3 (da) | 1999-01-29 | 2000-01-05 | Fremgangsmåde, beholder og indretning til overvågning af stofskifteaktiviteten i cellekulturer i flydende medier |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6730471B1 (fr) |
| EP (1) | EP1144586B1 (fr) |
| JP (1) | JP2002534997A (fr) |
| AT (1) | ATE222951T1 (fr) |
| CA (1) | CA2361119A1 (fr) |
| DE (2) | DE19903506C2 (fr) |
| DK (1) | DK1144586T3 (fr) |
| WO (1) | WO2000044876A2 (fr) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10003521A1 (de) | 2000-01-27 | 2001-08-09 | Medigene Ag | Vorrichtung zum Herstellen eines dreidimensionalen Matrixkörpers, Multi-Well-Platte, Lösung zum Kultivieren von Säugerkardiomyocyten, Verfahren zum Kultivieren einer Zellkultur, Vorrichtung für die Messung isometrischer Kraftparameter von Zellkulturen sowie Verfahren zum meßbaren Verfolgen von Kontraktionen eines in eine Trägersubstanz eingelagerten Zellgewebes |
| DE10136472A1 (de) * | 2001-07-23 | 2003-02-20 | Inst Chemo Biosensorik | Vorrichtung und Verfahren für den Nachweis lebender Mikroorganismen, eukaryotischer Zellen oder Organellen |
| DE10204531A1 (de) * | 2002-02-01 | 2003-08-21 | Inst Chemo Biosensorik | Deckelelement |
| ES2208127B1 (es) * | 2002-11-28 | 2005-09-01 | Universitat Politecnica De Catalunya | Sistema modular de multiples minibiorreactores automatizados para screenning multifuncional (hts) en biotecnologia. |
| BR0317668A (pt) * | 2002-12-23 | 2005-12-06 | Unisense As | Dispositivo e método para medição não-invasiva da taxa metabólica individual de uma partìcula de metabolização substancialmente esférica |
| US7276351B2 (en) * | 2003-09-10 | 2007-10-02 | Seahorse Bioscience | Method and device for measuring multiple physiological properties of cells |
| CA2552717C (fr) | 2004-01-07 | 2011-11-29 | Levtech, Inc. | Sac melangeur a arroseur integre et receptacle pour detecteur |
| DE102004016361B4 (de) * | 2004-04-01 | 2006-07-06 | Cybio Ag | Optisches Analysenmessgerät für Fluoreszenzmessungen an Multiprobenträgern |
| EP1778828B1 (fr) * | 2004-08-16 | 2012-12-19 | Sartorius Stedim Switzerland AG | Bioreacteur |
| DE102004051830B4 (de) * | 2004-10-25 | 2007-12-13 | Roche Diagnostics Gmbh | Multifunktionales Referenzsystem bei Analytbestimmungen durch Fluoreszenz |
| JP5451073B2 (ja) * | 2005-10-14 | 2014-03-26 | ユニセンス・ファーティリテック・アクティーゼルスカブ | 細胞集団における変化の決定 |
| US8603806B2 (en) * | 2005-11-02 | 2013-12-10 | The Ohio State Universtiy Research Foundation | Materials and methods for cell-based assays |
| DE102006001623B4 (de) * | 2006-01-11 | 2009-05-07 | Sartorius Stedim Biotech Gmbh | Behälter und Verfahren zum Mischen von Medien |
| JP5731748B2 (ja) * | 2006-06-16 | 2015-06-10 | ウニセンス フェルティリテック アー/エス | 卵割球の分裂および運動に基づく胚品質の評価 |
| EP2044438B1 (fr) | 2006-07-24 | 2017-11-01 | Biocer-Entwicklungs-GmbH | Installation pour des mesures en ligne sur des cellules |
| ES2363406T3 (es) | 2007-06-29 | 2011-08-03 | Unisense Fertilitech A/S | Dispositivo, sistema y método para monitorizar y/o cultivar objetos microscópicos. |
| KR100860958B1 (ko) | 2007-08-08 | 2008-09-30 | 전남대학교산학협력단 | 광학센서막 부착형 다채널 소형 생물반응기 |
| US8580566B2 (en) * | 2007-09-24 | 2013-11-12 | Arborgen Inc. | Apparatus for and method of preparing plant tissue for plant production |
| DE102008011013B4 (de) * | 2008-02-25 | 2014-11-13 | Mevitec Gmbh | Verfahren und Einrichtung zur komplexen Stoffwechselanalyse |
| EP2098862B1 (fr) * | 2008-03-05 | 2012-11-21 | Japan Agency for Marine-Earth Science and Technology | Appareil de mesure de la teneur en oxygène dissous |
| EP2315823B1 (fr) * | 2008-07-05 | 2018-03-07 | Unisense Fertilitech A/S | Système d'identification individuel |
| DE102008050109B4 (de) * | 2008-07-21 | 2010-06-17 | Ancosys Gmbh | Optischer Sensor |
| WO2011000572A1 (fr) | 2009-07-02 | 2011-01-06 | Patenthandel Portfoliofonds I Gmbh & Co. Kg | Procédé et dispositif permettant de mettre en évidence des effets biologiques à long terme dans des cellules |
| DE102011000061B4 (de) * | 2011-01-09 | 2015-10-22 | Technische Universität Dresden | Perfusionsbioreaktor zum Kultivieren von Zellen auf Gerüstmaterialien |
| KR101301959B1 (ko) * | 2011-06-10 | 2013-08-30 | 한국기초과학지원연구원 | 플라즈마 진단을 위한 광학측정신호 수집 시스템 |
| DE102011081326A1 (de) * | 2011-08-22 | 2013-02-28 | Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG | Optischer Sensor, insbesondere zur Bestimmung von Stoffkonzentrationen in wässrigen Lösungen mittels einer Fluoreszenzmessung |
| US8545759B2 (en) * | 2011-10-21 | 2013-10-01 | Therapeutic Proteins International, LLC | Noninvasive bioreactor monitoring |
| JP6326058B2 (ja) * | 2012-11-13 | 2018-05-16 | アジレント・テクノロジーズ・インクAgilent Technologies, Inc. | 制御された媒体流動上での三次元組織測定のための装置、インサート、および方法 |
| DE102013108189A1 (de) | 2013-07-31 | 2015-02-05 | Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG | Anordnung zur optischen Messung einer Prozessgröße und Messgerät umfassend eine solche |
| US20150125899A1 (en) * | 2013-11-07 | 2015-05-07 | Rebecca Willits | Fluorescence-assisted counting apparatus for qualitative and/or quantitative measurement of fluorescently tagged particles |
| DE102014000816A1 (de) * | 2014-01-22 | 2015-07-23 | Technische Universität Bergakademie Freiberg | Kammersystem für die Analyse von Gasflüssen von Ökosystemen |
| JP6740590B2 (ja) * | 2015-10-23 | 2020-08-19 | 株式会社デンソー | 光合成微生物の培養装置及び培養方法 |
| DE102015119756B3 (de) | 2015-11-16 | 2016-11-17 | Sartorius Stedim Biotech Gmbh | Mischvorrichtung zum Durchmischen eines Bioreaktors aufweisend eine Synchronisierungseinrichtung |
| KR101837718B1 (ko) * | 2016-11-30 | 2018-03-12 | (주) 동국이노텍 | 웰 플레이트용 형광패치 제조방법 및 형광패치 |
| JP7021665B2 (ja) * | 2017-03-31 | 2022-02-17 | ソニーグループ株式会社 | 情報処理装置、情報処理方法、及び細胞分析システム |
| US11639925B2 (en) | 2017-04-06 | 2023-05-02 | Agilent Technologies, Inc. | Method and apparatus for measuring physiological properties of biological samples |
| DE102018122510A1 (de) * | 2018-09-14 | 2020-03-19 | Endress+Hauser Conducta Gmbh+Co. Kg | Optischer Sensor |
| JP7190167B2 (ja) * | 2019-02-18 | 2022-12-15 | 大学共同利用機関法人自然科学研究機構 | 測定装置 |
| JP2023522862A (ja) * | 2020-04-21 | 2023-06-01 | プロフサ,インコーポレイテッド | 分析物のインビトロ検知のための方法及びシステム |
| JP7729031B2 (ja) * | 2020-11-13 | 2025-08-26 | 東洋製罐グループホールディングス株式会社 | 細胞培養システム、及び細胞の増殖性の検出方法 |
| WO2024162162A1 (fr) * | 2023-01-30 | 2024-08-08 | 株式会社村田製作所 | Module de mesure de capteur optique, ensemble de mesure de capteur optique et dispositif de détection |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4548907A (en) | 1983-09-14 | 1985-10-22 | Allied Corporation | Fluorescent fluid determination method and apparatus |
| JPS62503191A (ja) | 1985-07-03 | 1987-12-17 | インタ−ナシヨナル バイオメデイクス,インコ−ポレイテツド | 酸素濃度測定のための方法および組成物 |
| WO1988006287A1 (fr) * | 1987-02-20 | 1988-08-15 | Terumo Kabushiki Kaisha | Capteur pour mesurer la concentration d'oxygene dissous |
| US5432061A (en) * | 1992-09-01 | 1995-07-11 | Becton Dickinson And Company | Method and apparatus for detecting microorganisms |
| US5371016A (en) * | 1993-04-26 | 1994-12-06 | Becton, Dickinson And Company | Detecting biological activities in culture vials |
| US5552319A (en) * | 1993-07-20 | 1996-09-03 | Biochem Technology, Inc. | Apparatus and method for monitoring and controlling biological activity in wastewater and controlling the treatment thereof |
| US5601997A (en) | 1995-02-03 | 1997-02-11 | Tchao; Ruy | Chemotaxis assay procedure |
| JP4066200B2 (ja) * | 1995-06-05 | 2008-03-26 | アクゾ・ノベル・エヌ・ベー | 微生物を検出するデバイスおよび方法 |
| JPH09313165A (ja) * | 1996-05-30 | 1997-12-09 | Rikagaku Kenkyusho | バイオリアクタ汎用検出装置 |
| ATE227338T1 (de) * | 1998-03-18 | 2002-11-15 | Massachusetts Inst Technology | Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane |
-
1999
- 1999-01-29 DE DE19903506A patent/DE19903506C2/de not_active Expired - Fee Related
-
2000
- 2000-01-05 DK DK00903502T patent/DK1144586T3/da active
- 2000-01-05 CA CA002361119A patent/CA2361119A1/fr not_active Abandoned
- 2000-01-05 US US09/890,228 patent/US6730471B1/en not_active Expired - Fee Related
- 2000-01-05 AT AT00903502T patent/ATE222951T1/de not_active IP Right Cessation
- 2000-01-05 JP JP2000596121A patent/JP2002534997A/ja active Pending
- 2000-01-05 WO PCT/DE2000/000071 patent/WO2000044876A2/fr not_active Ceased
- 2000-01-05 DE DE50000413T patent/DE50000413D1/de not_active Expired - Fee Related
- 2000-01-05 EP EP00903502A patent/EP1144586B1/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE50000413D1 (de) | 2002-10-02 |
| EP1144586B1 (fr) | 2002-08-28 |
| WO2000044876A2 (fr) | 2000-08-03 |
| ATE222951T1 (de) | 2002-09-15 |
| EP1144586A2 (fr) | 2001-10-17 |
| US6730471B1 (en) | 2004-05-04 |
| DE19903506C2 (de) | 2002-04-04 |
| CA2361119A1 (fr) | 2000-08-03 |
| DE19903506A1 (de) | 2000-08-10 |
| WO2000044876A3 (fr) | 2000-11-16 |
| JP2002534997A (ja) | 2002-10-22 |
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