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DK1037627T3 - Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske... - Google Patents

Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske...

Info

Publication number
DK1037627T3
DK1037627T3 DK99928600T DK99928600T DK1037627T3 DK 1037627 T3 DK1037627 T3 DK 1037627T3 DK 99928600 T DK99928600 T DK 99928600T DK 99928600 T DK99928600 T DK 99928600T DK 1037627 T3 DK1037627 T3 DK 1037627T3
Authority
DK
Denmark
Prior art keywords
dihydrodibenz
oxepin
propylidene
allergic
dimethylamino
Prior art date
Application number
DK99928600T
Other languages
Danish (da)
English (en)
Inventor
John M Yanni
Daniel A Gamache
Lori K Weimer
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of DK1037627T3 publication Critical patent/DK1037627T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99928600T 1998-07-14 1999-06-15 Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske... DK1037627T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9276298P 1998-07-14 1998-07-14
PCT/US1999/013275 WO2000003705A1 (fr) 1998-07-14 1999-06-15 Utilisation d'acide 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz£b,e]oxepine-2-acetique dans la production d'un medicament de traitement de troubles ophtalmiques inflammatoires non allergiques et de prevention de la neoformation de vaisseaux sanguins oculaires

Publications (1)

Publication Number Publication Date
DK1037627T3 true DK1037627T3 (da) 2001-10-01

Family

ID=22235027

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99928600T DK1037627T3 (da) 1998-07-14 1999-06-15 Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske...

Country Status (17)

Country Link
EP (1) EP1037627B1 (fr)
JP (1) JP2002520355A (fr)
KR (1) KR100598723B1 (fr)
CN (1) CN1114401C (fr)
AR (1) AR019916A1 (fr)
AT (1) ATE203668T1 (fr)
AU (1) AU742237B2 (fr)
BR (1) BR9906772A (fr)
CA (1) CA2306393C (fr)
DE (1) DE69900207T2 (fr)
DK (1) DK1037627T3 (fr)
ES (1) ES2159209T3 (fr)
GR (1) GR3036422T3 (fr)
PT (1) PT1037627E (fr)
TW (1) TW561046B (fr)
WO (1) WO2000003705A1 (fr)
ZA (1) ZA200001593B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60008730T2 (de) * 1999-06-18 2004-08-05 Alcon Manufacturing Ltd., Fort Worth Methode zur konzentrationsbestimmung einer amphipathischen antihistaminischen verbindung durch bestimmung ihrer oberflächen aktivitäts einstufung
AU2002224337A1 (en) * 2000-10-23 2002-05-06 Alcon, Inc. Use of hydroperoxyeicosatetraenoic acid derivatives following refractive surgery
US7112588B2 (en) 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
US6872382B1 (en) 2001-05-21 2005-03-29 Alcon, Inc. Use of selective PDE IV inhibitors to treat dry eye disorders
ES2278049T3 (es) 2001-05-21 2007-08-01 Alcon, Inc. Uso de inhibidores de proteasoma para tratar trastornos de ojo seco.
JP2004527578A (ja) 2001-05-21 2004-09-09 アルコン，インコーポレイテッド ドライアイ障害を処置するためのＮＦ−κＢインヒビターの使用
US6645994B1 (en) 2001-06-01 2003-11-11 Alcon, Inc. Method of treating dry eye disorders
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
US7977376B2 (en) 2001-06-27 2011-07-12 Novartis Ag Olopatadine formulations for topical nasal administration
EP1583527A1 (fr) * 2002-06-14 2005-10-12 Alcon, Inc. Utilisation de composes d'acide hydroxyeicosatetraenoique pour traiter des troubles inflammatoires ophtalmiques
ES2397574T3 (es) * 2002-07-30 2013-03-08 Omeros Corporation Procedimiento y soluciones de irrigación oftalmológica
CA2497977A1 (fr) 2002-09-20 2004-04-01 Alcon, Inc. Utilisation d'inhibiteurs de la synthese des cytokines dans le traitement des troubles associes a la keratoconjonctivite seche
WO2004093878A1 (fr) * 2003-04-16 2004-11-04 Alcon, Inc. Utilisation de derives de pyridazine fondue servant a traiter des troubles lies a la secheresse de l'oeil
US20050232972A1 (en) 2004-04-15 2005-10-20 Steven Odrich Drug delivery via punctal plug
US7923471B2 (en) 2004-05-14 2011-04-12 Alcon, Inc. Method of treating dry eye disorders and uveitis
CN101052435B (zh) 2004-07-02 2010-12-08 Qlt塞子传递公司 治疗介质递送装置
US7223737B1 (en) 2004-08-13 2007-05-29 Alcon, Inc. Method of treating dry eye disorders using glycosides
AU2006247136C1 (en) 2005-05-17 2020-01-16 Bausch + Lomb Ireland Limited Compositions and methods for treatment of eye disorders
US7745461B1 (en) 2006-02-27 2010-06-29 Alcon Research, Ltd. Method of treating dry eye disorders
TWI454286B (zh) 2006-03-17 2014-10-01 Johnson & Johnson Vision Care 安定氧化性不安定組合物之方法
ES2640458T3 (es) 2006-03-31 2017-11-03 Mati Therapeutics Inc. Implantes del sistema de drenaje nasolagrimal para terapia medicamentosa
EP3372205A1 (fr) 2007-09-07 2018-09-12 Mati Therapeutics Inc. Détection d'un implant lacrymal
US8207226B1 (en) 2008-06-03 2012-06-26 Alcon Research, Ltd. Use of FAAH antagonists for treating dry eye and ocular pain
EP2496233A1 (fr) 2009-11-06 2012-09-12 Alcon Research, Ltd. Compléments nutritionnels destinés à soulager la sécheresse oculaire
AU2013201465B2 (en) 2012-10-24 2016-03-03 Rayner Intraocular Lenses Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
TWI809304B (zh) 2014-12-01 2023-07-21 奥默羅斯公司 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液
US12146187B2 (en) 2016-06-20 2024-11-19 Novartis Ag Methods of treating dry eye disease using TNF alpha antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6310784A (ja) * 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
JPH02138215A (ja) * 1988-08-05 1990-05-28 Dai Ichi Seiyaku Co Ltd 抗アレルギー・抗炎症剤
IE920499A1 (en) * 1991-02-21 1992-08-26 Merck Frosst Canada Inc Quinoline-containing ketoacids as leukotriene antagonists
ZA924953B (en) * 1991-07-25 1993-04-28 Univ Louisville Res Found Method of treating ocular inflammation
JP3453152B2 (ja) * 1992-04-06 2003-10-06 格 冨山 抗炎症点眼剤
FR2701948B1 (fr) * 1993-02-22 1996-07-26 Exsymol Sa Produit de couplage de l'histamine ou l'histamine méthyl-substituée et d'un acide aminé, procédé de préparation et applications thérapeutiques, cosmétologiques et agroalimentaires.
CA2159091C (fr) * 1993-03-26 2006-12-19 Richard J. Sharpe Application topique et systemique de la buspirone ou de derives de celle-ci pour le traitement de conditions pathologiques associees aux reponses immunitaires
FR2711990B1 (fr) * 1993-11-05 1995-12-08 Exsymol Sa Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires.
JP2852607B2 (ja) * 1994-06-10 1999-02-03 雪印乳業株式会社 ドライアイ治療剤
US5641805A (en) * 1995-06-06 1997-06-24 Alcon Laboratories, Inc. Topical ophthalmic formulations for treating allergic eye diseases
JPH1067684A (ja) * 1996-06-17 1998-03-10 Mitsubishi Chem Corp 涙液分泌促進剤
JP2002514194A (ja) * 1996-11-19 2002-05-14 ザ スキーペンズ アイ リサーチ インスティテュート インコーポレイテッド 角膜移植拒否又は眼疾におけるｉｌ―１ｒａの局所使用

Also Published As

Publication number Publication date
BR9906772A (pt) 2000-09-26
KR100598723B1 (ko) 2006-07-11
CN1275078A (zh) 2000-11-29
CA2306393A1 (fr) 2000-01-27
AR019916A1 (es) 2002-03-27
AU742237B2 (en) 2001-12-20
HK1030362A1 (en) 2001-05-04
AU4563499A (en) 2000-02-07
JP2002520355A (ja) 2002-07-09
KR20010024508A (ko) 2001-03-26
EP1037627B1 (fr) 2001-08-01
ES2159209T3 (es) 2001-09-16
WO2000003705A1 (fr) 2000-01-27
ATE203668T1 (de) 2001-08-15
ZA200001593B (en) 2000-10-25
CA2306393C (fr) 2008-12-23
DE69900207D1 (de) 2001-09-06
PT1037627E (pt) 2001-11-30
DE69900207T2 (de) 2001-11-22
EP1037627A1 (fr) 2000-09-27
GR3036422T3 (en) 2001-11-30
TW561046B (en) 2003-11-11
CN1114401C (zh) 2003-07-16

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