DK1024137T3 - Opspaltning af aminer - Google Patents
Opspaltning af aminerInfo
- Publication number
- DK1024137T3 DK1024137T3 DK98930811T DK98930811T DK1024137T3 DK 1024137 T3 DK1024137 T3 DK 1024137T3 DK 98930811 T DK98930811 T DK 98930811T DK 98930811 T DK98930811 T DK 98930811T DK 1024137 T3 DK1024137 T3 DK 1024137T3
- Authority
- DK
- Denmark
- Prior art keywords
- enantiomer
- acid
- compound
- dextrorotatory
- racemic mixture
- Prior art date
Links
- 150000001412 amines Chemical class 0.000 title 1
- 238000003776 cleavage reaction Methods 0.000 title 1
- 230000007017 scission Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Rheumatology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Luminescent Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Gyroscopes (AREA)
- Plural Heterocyclic Compounds (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES009701538A ES2130079B1 (es) | 1997-07-10 | 1997-07-10 | Resolucion de aminas |
| PCT/ES1998/000195 WO1999002500A1 (fr) | 1997-07-10 | 1998-07-06 | Resolution d'amines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1024137T3 true DK1024137T3 (da) | 2003-12-22 |
Family
ID=8300022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98930811T DK1024137T3 (da) | 1997-07-10 | 1998-07-06 | Opspaltning af aminer |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6187930B1 (fr) |
| EP (1) | EP1024137B1 (fr) |
| JP (1) | JP2001509505A (fr) |
| AT (1) | ATE250585T1 (fr) |
| AU (1) | AU8111798A (fr) |
| CA (1) | CA2295800A1 (fr) |
| DE (1) | DE69818495T2 (fr) |
| DK (1) | DK1024137T3 (fr) |
| ES (2) | ES2130079B1 (fr) |
| NO (1) | NO314581B1 (fr) |
| PT (1) | PT1024137E (fr) |
| WO (1) | WO1999002500A1 (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5986135A (en) * | 1998-09-25 | 1999-11-16 | American Cyanamid Company | Fungicidal trifluoromethylalkylamino-triazolopyrimidines |
| US6687187B2 (en) * | 2000-08-11 | 2004-02-03 | Phonak Ag | Method for directional location and locating system |
| US20040142929A1 (en) * | 2001-07-06 | 2004-07-22 | Ramon Merce-Vidal | Derivatives of aryl (or heteroaryl) azolylcarbinoles for the treatment of urinary incontinence |
| US7182210B2 (en) | 2003-08-19 | 2007-02-27 | Rock-Tenn Shared Services, Llc | Adjustable shelving system |
| TW200533657A (en) * | 2004-02-17 | 2005-10-16 | Esteve Labor Dr | Substituted pyrazoline compounds, their preparation and use as medicaments |
| EP1584335A3 (fr) * | 2004-04-05 | 2006-02-22 | Laboratorios Del Dr. Esteve, S.A. | Combinaison de substances actives comprenant un composé carbinol et un opioïde |
| ES2244326B1 (es) * | 2004-04-05 | 2007-02-16 | Laboratorios Del Dr. Esteve, S.A. | Combinacion de substancias activas. |
| US20060040924A1 (en) * | 2004-06-22 | 2006-02-23 | Laboratorios Dr. Esteve S.A. | Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of renal colic |
| EP1671968A1 (fr) | 2004-12-17 | 2006-06-21 | Laboratorios Del Dr. Esteve, S.A. | Procédé pour la préparation des énantiomères de thiénylazolylalcoxyéthanamines |
| EP1671953A1 (fr) | 2004-12-17 | 2006-06-21 | Laboratorios Del Dr. Esteve, S.A. | Procédé d'obtention de Cizolirtine et de ses énantionmères |
| EP1674465A1 (fr) | 2004-12-27 | 2006-06-28 | Laboratorios Del Dr. Esteve, S.A. | Procédé pour l'obtention des enanntiomères des thienylazolylalkoxyethanamines. |
| EP1879854B1 (fr) * | 2005-05-10 | 2011-09-07 | Teva Pharmaceutical Industries Ltd | Resolution optique de l'acide 3-carbamoylmethyl-5-methyl hexanoique |
| ATE486841T1 (de) * | 2005-05-10 | 2010-11-15 | Teva Pharma | Verfahren zur herstellung von pregabalin und salzen daraus |
| EP1743890A1 (fr) * | 2005-07-15 | 2007-01-17 | Laboratorios Del Dr. Esteve, S.A. | Dérivés 4,5-dihydro-1H-pyrazole, leur, préparation et utilisation comme médicaments. |
| EP1743892A1 (fr) * | 2005-07-15 | 2007-01-17 | Laboratorios del Dr. Esteve S.A. | Composés pyrazoline substitués, leur préparation et utilisation comme médicaments |
| US7897589B2 (en) * | 2005-07-15 | 2011-03-01 | Laboratorios Del Dr. Esteve, S.A. | Substituted pyrazoline compounds, their preparation and use as medicaments |
| EP1757587A1 (fr) * | 2005-07-15 | 2007-02-28 | Laboratorios Del Dr. Esteve, S.A. | Composés de pyrazoline substituée, leur préparation et leur usage comme médicaments |
| US7563923B2 (en) | 2005-09-19 | 2009-07-21 | Teva Pharmaceutical Industries Ltd. | Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin |
| EP1820502A1 (fr) | 2006-02-10 | 2007-08-22 | Laboratorios Del Dr. Esteve, S.A. | Combinaisons de principes actifs comprenant de dérivés d' azolylcarbinol |
| WO2009158343A1 (fr) * | 2008-06-23 | 2009-12-30 | Teva Pharmaceutical Industries, Ltd. | Synthèse enzymatique stéréosélective de l’ester (s) ou (r)-isobutylglutarique |
| EP2151234A1 (fr) * | 2008-07-28 | 2010-02-10 | Laboratorios Del. Dr. Esteve, S.A. | Formulation pharmaceutique comprenant un composé récepteur CB1 dans une solution solide et/ou une dispersion solide |
| US20100291151A1 (en) * | 2009-04-21 | 2010-11-18 | Auspex Pharmaceuticals, Inc. | 1-methylpyrazole modulators of substance p, calcitonin gene-related peptide, adrenergic receptor, and/or 5-ht receptor |
| JP2011057619A (ja) * | 2009-09-10 | 2011-03-24 | Tokai Univ | 光学活性アミン化合物の製造方法、並びに、ジアステレオマー塩及びその製造方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2742147B1 (fr) * | 1995-12-06 | 1998-02-27 | Esteve Labor Dr | Procede de separation de carbinols |
| DE19601745C1 (de) * | 1996-01-19 | 1997-10-09 | Gruenenthal Gmbh | Verfahren zur Racematspaltung von Tramadol |
-
1997
- 1997-07-10 ES ES009701538A patent/ES2130079B1/es not_active Expired - Fee Related
-
1998
- 1998-07-06 AT AT98930811T patent/ATE250585T1/de not_active IP Right Cessation
- 1998-07-06 PT PT98930811T patent/PT1024137E/pt unknown
- 1998-07-06 DE DE69818495T patent/DE69818495T2/de not_active Expired - Fee Related
- 1998-07-06 CA CA002295800A patent/CA2295800A1/fr not_active Abandoned
- 1998-07-06 WO PCT/ES1998/000195 patent/WO1999002500A1/fr not_active Ceased
- 1998-07-06 AU AU81117/98A patent/AU8111798A/en not_active Abandoned
- 1998-07-06 US US09/462,326 patent/US6187930B1/en not_active Expired - Fee Related
- 1998-07-06 JP JP2000502028A patent/JP2001509505A/ja active Pending
- 1998-07-06 DK DK98930811T patent/DK1024137T3/da active
- 1998-07-06 ES ES98930811T patent/ES2209158T3/es not_active Expired - Lifetime
- 1998-07-06 EP EP98930811A patent/EP1024137B1/fr not_active Expired - Lifetime
-
2000
- 2000-01-07 NO NO20000089A patent/NO314581B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1024137E (pt) | 2004-01-30 |
| WO1999002500A1 (fr) | 1999-01-21 |
| NO314581B1 (no) | 2003-04-14 |
| ES2130079B1 (es) | 2000-01-16 |
| DE69818495T2 (de) | 2004-07-01 |
| AU8111798A (en) | 1999-02-08 |
| DE69818495D1 (de) | 2003-10-30 |
| US6187930B1 (en) | 2001-02-13 |
| ATE250585T1 (de) | 2003-10-15 |
| EP1024137B1 (fr) | 2003-09-24 |
| ES2209158T3 (es) | 2004-06-16 |
| NO20000089D0 (no) | 2000-01-07 |
| EP1024137A1 (fr) | 2000-08-02 |
| CA2295800A1 (fr) | 1999-01-21 |
| ES2130079A1 (es) | 1999-06-16 |
| JP2001509505A (ja) | 2001-07-24 |
| NO20000089L (no) | 2000-02-22 |
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