DK0878195T3 - Anvendelse af en 2-aroyl-3-arylbenzo(b)thiophenforbindelse til reduktion af fibrinogenniveauerne - Google Patents
Anvendelse af en 2-aroyl-3-arylbenzo(b)thiophenforbindelse til reduktion af fibrinogenniveauerneInfo
- Publication number
- DK0878195T3 DK0878195T3 DK98303055T DK98303055T DK0878195T3 DK 0878195 T3 DK0878195 T3 DK 0878195T3 DK 98303055 T DK98303055 T DK 98303055T DK 98303055 T DK98303055 T DK 98303055T DK 0878195 T3 DK0878195 T3 DK 0878195T3
- Authority
- DK
- Denmark
- Prior art keywords
- aroyl
- arylbenzo
- thiophene compound
- fibrinogen levels
- reduce fibrinogen
- Prior art date
Links
- 102000008946 Fibrinogen Human genes 0.000 title abstract 2
- 108010049003 Fibrinogen Proteins 0.000 title abstract 2
- 229940012952 fibrinogen Drugs 0.000 title abstract 2
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Divinylene sulfide Natural products C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 1
- 229930192474 thiophene Natural products 0.000 title 1
- -1 thiophene compound Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Zoology (AREA)
- Vascular Medicine (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Nonmetallic Welding Materials (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4459197P | 1997-04-22 | 1997-04-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0878195T3 true DK0878195T3 (da) | 2002-07-15 |
Family
ID=21933208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98303055T DK0878195T3 (da) | 1997-04-22 | 1998-04-21 | Anvendelse af en 2-aroyl-3-arylbenzo(b)thiophenforbindelse til reduktion af fibrinogenniveauerne |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6025373A (da) |
| EP (1) | EP0878195B1 (da) |
| JP (1) | JP2001524101A (da) |
| KR (1) | KR20010012084A (da) |
| CN (1) | CN1254255A (da) |
| AT (1) | ATE219364T1 (da) |
| AU (1) | AU741720B2 (da) |
| BR (1) | BR9809286A (da) |
| CA (1) | CA2287196A1 (da) |
| DE (1) | DE69806098T2 (da) |
| DK (1) | DK0878195T3 (da) |
| EA (1) | EA002237B1 (da) |
| ES (1) | ES2178111T3 (da) |
| HU (1) | HUP0002727A3 (da) |
| ID (1) | ID22910A (da) |
| IL (1) | IL132504A0 (da) |
| NO (1) | NO995132D0 (da) |
| NZ (1) | NZ500389A (da) |
| PL (1) | PL336638A1 (da) |
| PT (1) | PT878195E (da) |
| TR (1) | TR199902605T2 (da) |
| WO (1) | WO1998047365A1 (da) |
| ZA (1) | ZA983298B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6103740A (en) * | 1997-08-21 | 2000-08-15 | Eli Lilly And Company | Methods for lowering platelet counts |
| FR2777784B1 (fr) * | 1998-04-27 | 2004-03-19 | Arepa | Composition pharmaceutique a base d'estrogene et de progesterone |
| US6353003B1 (en) | 1998-06-17 | 2002-03-05 | Eli Lilly And Company | Method for reducing levels of homocysteine and C-reactive protein |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
| US4380635A (en) * | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
| US5075321A (en) * | 1987-03-24 | 1991-12-24 | University Of Pennsylvania | Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes |
| JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
| EP0612500B1 (en) * | 1991-12-17 | 1998-10-28 | DYNAMICS IMAGING, Inc. | Method and device for diagnosis of living organism |
| US5482949A (en) * | 1993-03-19 | 1996-01-09 | Eli Lilly And Company | Sulfonate derivatives of 3-aroylbenzo[b]thiophenes |
| US5445941A (en) * | 1993-06-21 | 1995-08-29 | Eli Lilly And Company | Method for screening anti-osteoporosis agents |
| JPH07149638A (ja) * | 1993-10-15 | 1995-06-13 | Eli Lilly & Co | 耐性新生物の治療法 |
| US5476862A (en) * | 1993-12-21 | 1995-12-19 | Eli Lilly And Company | Methods of increasing thrombomodulin expression |
| US5441965A (en) * | 1993-12-21 | 1995-08-15 | Eli Lilly And Company | Methods of inhibiting thrombin |
| FI973235L (fi) * | 1995-02-06 | 1997-08-05 | Lilly Co Eli | Menetelmä IL-6:n vaikutusten inhiboimiseksi |
| US5731328A (en) * | 1995-10-10 | 1998-03-24 | Eli Lilly And Company | Methods of inhibiting plasminogen activator inhibitor 1 |
-
1998
- 1998-04-08 US US09/056,991 patent/US6025373A/en not_active Expired - Fee Related
- 1998-04-20 ID IDW991253A patent/ID22910A/id unknown
- 1998-04-20 AU AU72503/98A patent/AU741720B2/en not_active Ceased
- 1998-04-20 KR KR1019997009721A patent/KR20010012084A/ko not_active Withdrawn
- 1998-04-20 HU HU0002727A patent/HUP0002727A3/hu unknown
- 1998-04-20 EA EA199900959A patent/EA002237B1/ru not_active IP Right Cessation
- 1998-04-20 NZ NZ500389A patent/NZ500389A/en unknown
- 1998-04-20 WO PCT/US1998/007862 patent/WO1998047365A1/en not_active Ceased
- 1998-04-20 CA CA002287196A patent/CA2287196A1/en not_active Abandoned
- 1998-04-20 TR TR1999/02605T patent/TR199902605T2/xx unknown
- 1998-04-20 IL IL13250498A patent/IL132504A0/xx unknown
- 1998-04-20 PL PL98336638A patent/PL336638A1/xx unknown
- 1998-04-20 JP JP54620898A patent/JP2001524101A/ja active Pending
- 1998-04-20 CN CN98804368A patent/CN1254255A/zh active Pending
- 1998-04-20 ZA ZA9803298A patent/ZA983298B/xx unknown
- 1998-04-20 BR BR9809286-3A patent/BR9809286A/pt not_active IP Right Cessation
- 1998-04-21 DE DE69806098T patent/DE69806098T2/de not_active Expired - Fee Related
- 1998-04-21 DK DK98303055T patent/DK0878195T3/da active
- 1998-04-21 PT PT98303055T patent/PT878195E/pt unknown
- 1998-04-21 ES ES98303055T patent/ES2178111T3/es not_active Expired - Lifetime
- 1998-04-21 AT AT98303055T patent/ATE219364T1/de not_active IP Right Cessation
- 1998-04-21 EP EP98303055A patent/EP0878195B1/en not_active Expired - Lifetime
-
1999
- 1999-10-21 NO NO995132A patent/NO995132D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EA002237B1 (ru) | 2002-02-28 |
| PT878195E (pt) | 2002-09-30 |
| CA2287196A1 (en) | 1998-10-29 |
| HUP0002727A3 (en) | 2001-09-28 |
| ATE219364T1 (de) | 2002-07-15 |
| US6025373A (en) | 2000-02-15 |
| ID22910A (id) | 1999-12-16 |
| WO1998047365A1 (en) | 1998-10-29 |
| HUP0002727A2 (hu) | 2001-08-28 |
| ES2178111T3 (es) | 2002-12-16 |
| CN1254255A (zh) | 2000-05-24 |
| DE69806098T2 (de) | 2003-01-02 |
| AU741720B2 (en) | 2001-12-06 |
| AU7250398A (en) | 1998-11-13 |
| KR20010012084A (ko) | 2001-02-15 |
| NZ500389A (en) | 2001-07-27 |
| EA199900959A1 (ru) | 2000-06-26 |
| JP2001524101A (ja) | 2001-11-27 |
| IL132504A0 (en) | 2001-03-19 |
| DE69806098D1 (de) | 2002-07-25 |
| BR9809286A (pt) | 2000-07-04 |
| NO995132L (no) | 1999-10-21 |
| ZA983298B (en) | 1999-10-20 |
| MX9909548A (es) | 2003-02-27 |
| TR199902605T2 (xx) | 2000-02-21 |
| NO995132D0 (no) | 1999-10-21 |
| EP0878195B1 (en) | 2002-06-19 |
| EP0878195A1 (en) | 1998-11-18 |
| PL336638A1 (en) | 2000-07-03 |
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