DK1098638T3 - Anvendelse af en glucoseoptagelsesforstærker til reduktion af post-iskæmisk læsion i hjertet - Google Patents

Anvendelse af en glucoseoptagelsesforstærker til reduktion af post-iskæmisk læsion i hjertet

Info

Publication number: DK1098638T3
Authority: DK; Denmark
Prior art keywords: heart; glucose uptake; reduce post; ischemic lesion; uptake enhancer
Prior art date: 1998-07-21

Application number

DK99934911T

Other languages

Danish (da)

English (en)

Inventor

Antoine Michel Bril

Nassirah Khandoudi

Robin Edwin Buckingham

Original Assignee

Smithkline Beecham Plc

Glaxosmithkline Lab Sas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-21

Filing date

1999-07-21

Publication date

2006-06-19

1998-07-21 Priority claimed from GBGB9815871.0A external-priority patent/GB9815871D0/en

1998-07-21 Priority claimed from GBGB9815872.8A external-priority patent/GB9815872D0/en

1999-07-21 Application filed by Smithkline Beecham Plc, Glaxosmithkline Lab Sas filed Critical Smithkline Beecham Plc

2006-06-19 Application granted granted Critical

2006-06-19 Publication of DK1098638T3 publication Critical patent/DK1098638T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Organic Chemistry (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Thiazole And Isothizaole Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK99934911T 1998-07-21 1999-07-21 Anvendelse af en glucoseoptagelsesforstærker til reduktion af post-iskæmisk læsion i hjertet DK1098638T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9815871.0A GB9815871D0 (en)	1998-07-21	1998-07-21	Novel compound
GBGB9815872.8A GB9815872D0 (en)	1998-07-21	1998-07-21	Novel method

Publications (1)

Publication Number	Publication Date
DK1098638T3 true DK1098638T3 (da)	2006-06-19

Family

ID=26314086

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99934911T DK1098638T3 (da)	1998-07-21	1999-07-21	Anvendelse af en glucoseoptagelsesforstærker til reduktion af post-iskæmisk læsion i hjertet

Country Status (35)

Country	Link
EP (2)	EP1098638B1 (cs)
JP (1)	JP2002521325A (cs)
KR (1)	KR20010079550A (cs)
CN (1)	CN1167416C (cs)
AP (1)	AP1416A (cs)
AR (1)	AR020614A1 (cs)
AT (1)	ATE318588T1 (cs)
AU (1)	AU5053599A (cs)
BG (1)	BG105251A (cs)
BR (1)	BR9912144A (cs)
CA (1)	CA2338216A1 (cs)
CO (1)	CO5060465A1 (cs)
CY (1)	CY1106078T1 (cs)
CZ (1)	CZ2001250A3 (cs)
DE (1)	DE69930125T2 (cs)
DK (1)	DK1098638T3 (cs)
DZ (1)	DZ2854A1 (cs)
EA (1)	EA004772B1 (cs)
ES (1)	ES2259839T3 (cs)
GC (1)	GC0000173A (cs)
HU (1)	HUP0103870A3 (cs)
ID (1)	ID27850A (cs)
IL (1)	IL140741A0 (cs)
MA (1)	MA26662A1 (cs)
NO (1)	NO20010293L (cs)
NZ (1)	NZ509175A (cs)
OA (1)	OA11583A (cs)
PE (1)	PE20000881A1 (cs)
PL (1)	PL345663A1 (cs)
PT (1)	PT1098638E (cs)
SI (1)	SI1098638T1 (cs)
SK (1)	SK1022001A3 (cs)
TR (1)	TR200100208T2 (cs)
TW (2)	TW200307532A (cs)
WO (1)	WO2000004889A1 (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6417212B1 (en)	1999-08-27	2002-07-09	Eli Lilly & Company	Modulators of peroxisome proliferator activated receptors
EP1292301A1 (en) *	2000-06-16	2003-03-19	Smithkline Beecham Plc	Treatment and prevention of cardiac insulin resistance associated conditions
MXPA04000695A (es)	2001-07-23	2005-08-26	Galileo Pharmaceuticals Inc	Compuestos citoprotectores, formulaciones farmaceuticas y cosmeticas y metodos.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0306228B1 (en) *	1987-09-04	1999-11-17	Beecham Group Plc	Substituted thiazolidinedione derivatives
JPH05202042A (ja) *	1992-01-24	1993-08-10	Sankyo Co Ltd	糖尿病性合併症治療剤
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
GB9611947D0 (en) *	1996-06-07	1996-08-07	Glaxo Group Ltd	Medicaments
US6277819B1 (en) *	1996-08-30	2001-08-21	Eli Lilly And Company	Use of GLP-1 or analogs in treatment of myocardial infarction
CA2265656A1 (en) *	1996-09-12	1998-03-19	Sankyo Company, Limited	Glutathione reductase activity potentiator containing troglitazone
EP1047423B1 (en) *	1997-11-19	2006-05-10	Takeda Pharmaceutical Company Limited	Novel apoptosis inhibitors
WO1999043326A1 (en) *	1998-02-24	1999-09-02	The Trustees Of The University Of Pennsylvania	Use of a cardiac purinoceptor to effect cellular glucose uptake
AU4005299A (en) *	1998-05-19	1999-12-06	Regents Of The University Of California, The	Thiazolidine and oxazolidine derivatives for the treatment of acute myocardial infarction and inhibition of cardiomyocyte apoptosis
US5968960A (en) *	1999-01-14	1999-10-19	The Regents Of The University Of California	Use of thiazolidinediones to ameliorate the adverse consequences of myocardial ischemia on myocardial function and metabolism

1999
- 1999-07-19 MA MA25690A patent/MA26662A1/fr unknown
- 1999-07-20 PE PE1999000726A patent/PE20000881A1/es not_active Application Discontinuation
- 1999-07-21 KR KR1020017000924A patent/KR20010079550A/ko not_active Ceased
- 1999-07-21 EP EP99934911A patent/EP1098638B1/en not_active Expired - Lifetime
- 1999-07-21 TW TW092103470A patent/TW200307532A/zh unknown
- 1999-07-21 DE DE69930125T patent/DE69930125T2/de not_active Expired - Fee Related
- 1999-07-21 EP EP04077992A patent/EP1523980A3/en not_active Withdrawn
- 1999-07-21 BR BR9912144-1A patent/BR9912144A/pt not_active IP Right Cessation
- 1999-07-21 DZ DZ990154A patent/DZ2854A1/xx active
- 1999-07-21 NZ NZ509175A patent/NZ509175A/en unknown
- 1999-07-21 CO CO99045729A patent/CO5060465A1/es unknown
- 1999-07-21 IL IL14074199A patent/IL140741A0/xx unknown
- 1999-07-21 HU HU0103870A patent/HUP0103870A3/hu unknown
- 1999-07-21 WO PCT/GB1999/002358 patent/WO2000004889A1/en not_active Ceased
- 1999-07-21 AP APAP/P/2001/002033A patent/AP1416A/en active
- 1999-07-21 CN CNB998089826A patent/CN1167416C/zh not_active Expired - Fee Related
- 1999-07-21 ES ES99934911T patent/ES2259839T3/es not_active Expired - Lifetime
- 1999-07-21 CA CA002338216A patent/CA2338216A1/en not_active Abandoned
- 1999-07-21 SI SI9930889T patent/SI1098638T1/sl unknown
- 1999-07-21 PT PT99934911T patent/PT1098638E/pt unknown
- 1999-07-21 DK DK99934911T patent/DK1098638T3/da active
- 1999-07-21 AT AT99934911T patent/ATE318588T1/de not_active IP Right Cessation
- 1999-07-21 TR TR2001/00208T patent/TR200100208T2/xx unknown
- 1999-07-21 GC GCP1999211 patent/GC0000173A/en active
- 1999-07-21 CZ CZ2001250A patent/CZ2001250A3/cs unknown
- 1999-07-21 TW TW088112356A patent/TWI239836B/zh not_active IP Right Cessation
- 1999-07-21 EA EA200100164A patent/EA004772B1/ru not_active IP Right Cessation
- 1999-07-21 ID IDW20010151A patent/ID27850A/id unknown
- 1999-07-21 OA OA1200100021A patent/OA11583A/en unknown
- 1999-07-21 JP JP2000560882A patent/JP2002521325A/ja not_active Withdrawn
- 1999-07-21 AR ARP990103577A patent/AR020614A1/es not_active Application Discontinuation
- 1999-07-21 PL PL99345663A patent/PL345663A1/xx not_active Application Discontinuation
- 1999-07-21 AU AU50535/99A patent/AU5053599A/en not_active Abandoned
- 1999-07-21 SK SK102-2001A patent/SK1022001A3/sk unknown
2001
- 2001-01-18 NO NO20010293A patent/NO20010293L/no unknown
- 2001-02-14 BG BG105251A patent/BG105251A/xx unknown
2006
- 2006-05-12 CY CY20061100616T patent/CY1106078T1/el unknown

Also Published As

Publication number	Publication date
NZ509175A (en)	2003-10-31
ATE318588T1 (de)	2006-03-15
EP1098638A1 (en)	2001-05-16
ID27850A (id)	2001-04-26
NO20010293D0 (no)	2001-01-18
ES2259839T3 (es)	2006-10-16
PL345663A1 (en)	2002-01-02
CO5060465A1 (es)	2001-07-30
AP1416A (en)	2005-06-13
KR20010079550A (ko)	2001-08-22
HUP0103870A3 (en)	2003-06-30
TR200100208T2 (tr)	2001-05-21
CA2338216A1 (en)	2000-02-03
EP1098638B1 (en)	2006-03-01
TWI239836B (en)	2005-09-21
HUP0103870A2 (hu)	2002-05-29
EP1523980A3 (en)	2009-03-18
OA11583A (en)	2004-07-01
MA26662A1 (fr)	2004-12-20
AR020614A1 (es)	2002-05-22
DZ2854A1 (fr)	2003-12-01
BG105251A (en)	2001-10-31
TW200307532A (en)	2003-12-16
WO2000004889A1 (en)	2000-02-03
AU5053599A (en)	2000-02-14
GC0000173A (en)	2006-03-29
CN1167416C (zh)	2004-09-22
SK1022001A3 (en)	2001-08-06
PT1098638E (pt)	2006-07-31
PE20000881A1 (es)	2000-10-07
CY1106078T1 (el)	2011-06-08
AP2001002033A0 (en)	2001-03-31
DE69930125D1 (de)	2006-04-27
BR9912144A (pt)	2001-04-03
NO20010293L (no)	2001-03-07
IL140741A0 (en)	2002-02-10
EA004772B1 (ru)	2004-08-26
EA200100164A1 (ru)	2001-08-27
EP1523980A2 (en)	2005-04-20
JP2002521325A (ja)	2002-07-16
SI1098638T1 (sl)	2006-06-30
CZ2001250A3 (cs)	2002-03-13
CN1310619A (zh)	2001-08-29
DE69930125T2 (de)	2006-10-05

Publication	Publication Date	Title
ID25476A (id)	2000-10-05	Komposisi-komposisi yang tidak dapat larut untuk mengontrol glukosa darah
ID28111A (id)	2001-05-03	Metoda untuk meningkatkan kesehatan kulit
FI20000416L (fi)	2001-08-23	Ihmiselimistöön liittyvä mittaus
ID22508A (id)	1999-10-28	Trokar untuk memasukkan implant-implant
ATE272998T1 (de)	2004-08-15	Hautreinigungszusammensetzung mit verbesserter stabilität
ID28947A (id)	2001-07-19	Metode untuk meringankan inkontinensia uriner wanita
DE69931855D1 (de)	2006-07-27	Hautpräparat
PT1017408E (pt)	2005-07-29	Utilizacao de tetra-hidrolipstatina no tratamento de diabetes de tipo ii
GB0014617D0 (en)	2000-08-09	Improvements relating to lancets
DK1098638T3 (da)	2006-06-19	Anvendelse af en glucoseoptagelsesforstærker til reduktion af post-iskæmisk læsion i hjertet
GB2353063B (en)	2001-07-11	Improvements in or relating to ladders
GB2348134B (en)	2003-06-18	Improvements in or relating to sphygmomanometers
GB2340939B (en)	2003-11-12	Improvements in or relating to diagnosis of disease
ID24504A (id)	2000-07-20	Metode untuk memperkuat fosfat estramustin pada pembuluh darah
GB9911539D0 (en)	1999-07-21	Improvements in or relating to connection arrangements
GB9902193D0 (en)	1999-03-24	Improvements in or relating to sphygmomanometers
ID27282A (id)	2001-03-22	Protein c polipeptida pada manusia
ID26986A (id)	2001-02-22	Penggunaan peningkat penerimaan glukosa untuk mengurangi apoptosis
ID28575A (id)	2001-06-07	Semprit untuk sekali pakai
ITAQ970012A0 (it)	1997-10-22	Soluzione per risolvere definitivamente la sudorazione dei piedi
GB9903622D0 (en)	1999-04-07	Improvements in or relating to footwear
SE9800539D0 (sv)	1998-02-21	Improvements in or relating to VDSL
GB9929229D0 (en)	2000-02-02	Improvements in or relating to balers
IT237654Y1 (it)	2000-09-26	Salva polsini
BR7600353U (pt)	1998-06-16	Engaste de palheta removível em artefato de adorno corporal