DK1053017T3 - Vacciner omfattende interleukin-12 og herpes simplex virusantigen - Google Patents

Vacciner omfattende interleukin-12 og herpes simplex virusantigen

Info

Publication number: DK1053017T3
Authority: DK; Denmark
Prior art keywords: interleukin; herpes simplex; simplex virus; vaccines; virus antigen
Prior art date: 1998-02-12

Application number

DK99905946T

Other languages

English (en)

Inventor

Eric M Mishkin

John H Eldridge

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-12

Filing date

1999-02-10

Publication date

2004-11-22

1999-02-10 Application filed by Wyeth Corp filed Critical Wyeth Corp

2004-11-22 Application granted granted Critical

2004-11-22 Publication of DK1053017T3 publication Critical patent/DK1053017T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Mycology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Communicable Diseases (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oncology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

DK99905946T 1998-02-12 1999-02-10 Vacciner omfattende interleukin-12 og herpes simplex virusantigen DK1053017T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7450398P	1998-02-12	1998-02-12
EP19990905946 EP1053017B1 (en)	1998-02-12	1999-02-10	Vaccines comprising interleukin-12 and herpes simplex viral antigen

Publications (1)

Publication Number	Publication Date
DK1053017T3 true DK1053017T3 (da)	2004-11-22

Family

ID=22119907

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99905946T DK1053017T3 (da)	1998-02-12	1999-02-10	Vacciner omfattende interleukin-12 og herpes simplex virusantigen

Country Status (15)

Country	Link
US (1)	US6488936B1 (da)
EP (1)	EP1053017B1 (da)
JP (1)	JP2002502884A (da)
KR (1)	KR100622716B1 (da)
CN (1)	CN1224422C (da)
AT (1)	ATE275421T1 (da)
AU (1)	AU764036B2 (da)
BR (1)	BR9907883A (da)
CA (1)	CA2320041A1 (da)
DE (1)	DE69919984T2 (da)
DK (1)	DK1053017T3 (da)
ES (1)	ES2226338T3 (da)
IL (1)	IL137811A (da)
PT (1)	PT1053017E (da)
WO (1)	WO1999040938A2 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1178825B1 (en) *	1999-05-13	2011-07-13	Wyeth Holdings Corporation	Adjuvant combination formulations
AU783730B2 (en) *	1999-12-17	2005-12-01	Wyeth Holdings Corporation	Method of enhancing immune responses to herpes simplex virus vaccine
WO2002034119A2 (en)	2000-10-27	2002-05-02	Immuno-Rx, Inc.	Vaccine immunotherapy for immune suppressed patients
US20070025958A1 (en)	2000-10-27	2007-02-01	Hadden John W	Vaccine immunotherapy
EA004744B1 (ru) *	2000-11-10	2004-08-26	Уайт Холдингз Корпорейшн	Комбинированные композиции адъювантов
US6867000B2 (en)	2000-12-07	2005-03-15	Wyeth Holdings Corporation	Method of enhancing immune responses to herpes
JP2004099584A (ja) *	2002-05-02	2004-04-02	Keio Gijuku	Ｈｓｖを用いた抗腫瘍剤
CN1301749C (zh) *	2005-12-09	2007-02-28	复旦大学	抗单纯疱疹病毒－2感染的多表位dna疫苗及其制备方法
US7790203B2 (en) *	2005-12-13	2010-09-07	Lowder Tom R	Composition and regimen for the treatment of herpes simplex virus, herpes zoster, and herpes genitalia epidermal herpetic lesions
CA2662921C (en)	2006-09-26	2018-11-20	Infectious Disease Research Institute	Vaccine and pharmaceutical compositions and kits and uses thereof in stimulating an immune response with a synthetic glucopyranosyl lipid adjuvant
US20090181078A1 (en)	2006-09-26	2009-07-16	Infectious Disease Research Institute	Vaccine composition containing synthetic adjuvant
AU2010248761B2 (en)	2009-05-15	2016-02-11	Irx Therapeutics, Inc.	Vaccine immunotherapy
CN102481312B (zh)	2009-06-05	2015-07-15	传染性疾病研究院	合成的吡喃葡萄糖脂佐剂
US8729058B2 (en)	2009-10-27	2014-05-20	Michael Zasloff	Methods and compositions for treating and preventing viral infections
CA2820202C (en)	2009-12-08	2018-06-12	Irx Therapeutics, Inc.	Method of reversing immune suppression of langerhans cells
CA2832307A1 (en)	2011-04-08	2012-10-18	Immune Design Corp.	Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
AU2013262691B2 (en)	2012-05-16	2018-12-20	Immune Design Corp.	Vaccines for HSV-2
EP3711768A1 (en)	2013-04-18	2020-09-23	Immune Design Corp.	Gla monotherapy for use in cancer treatment
US9463198B2 (en)	2013-06-04	2016-10-11	Infectious Disease Research Institute	Compositions and methods for reducing or preventing metastasis
AU2017261687B2 (en)	2016-05-10	2023-10-19	Hennepin Healthcare Research Institute	Cytokine signaling immunomodulators and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994022473A1 (en) *	1993-04-01	1994-10-13	University Of Washington	Use of interleukin 7 to improve vaccine potency
US5571515A (en) *	1994-04-18	1996-11-05	The Wistar Institute Of Anatomy & Biology	Compositions and methods for use of IL-12 as an adjuvant
IL114576A0 (en) *	1994-07-22	1995-11-27	Merck & Co Inc	Polynucleotide herpes virus vaccine
GB9422990D0 (en) *	1994-11-15	1995-01-04	Cortecs Ltd	Immunogenic compositions
WO1998008947A1 (en) *	1995-12-19	1998-03-05	The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services	Enhancement of dna immunization through the use of cytokines

1999
- 1999-02-10 DK DK99905946T patent/DK1053017T3/da active
- 1999-02-10 KR KR1020007008769A patent/KR100622716B1/ko not_active Expired - Fee Related
- 1999-02-10 WO PCT/US1999/002923 patent/WO1999040938A2/en not_active Ceased
- 1999-02-10 US US09/247,635 patent/US6488936B1/en not_active Expired - Fee Related
- 1999-02-10 AU AU25981/99A patent/AU764036B2/en not_active Ceased
- 1999-02-10 DE DE1999619984 patent/DE69919984T2/de not_active Expired - Fee Related
- 1999-02-10 AT AT99905946T patent/ATE275421T1/de not_active IP Right Cessation
- 1999-02-10 CA CA 2320041 patent/CA2320041A1/en not_active Abandoned
- 1999-02-10 JP JP2000531189A patent/JP2002502884A/ja active Pending
- 1999-02-10 EP EP19990905946 patent/EP1053017B1/en not_active Expired - Lifetime
- 1999-02-10 PT PT99905946T patent/PT1053017E/pt unknown
- 1999-02-10 CN CNB998043311A patent/CN1224422C/zh not_active Expired - Fee Related
- 1999-02-10 BR BR9907883A patent/BR9907883A/pt not_active Application Discontinuation
- 1999-02-10 IL IL13781199A patent/IL137811A/en not_active IP Right Cessation
- 1999-02-10 ES ES99905946T patent/ES2226338T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR20010040867A (ko)	2001-05-15
WO1999040938A2 (en)	1999-08-19
CN1299287A (zh)	2001-06-13
JP2002502884A (ja)	2002-01-29
CA2320041A1 (en)	1999-08-19
DE69919984T2 (de)	2005-11-17
AU2598199A (en)	1999-08-30
EP1053017B1 (en)	2004-09-08
US6488936B1 (en)	2002-12-03
DE69919984D1 (de)	2004-10-14
BR9907883A (pt)	2000-11-14
EP1053017A2 (en)	2000-11-22
CN1224422C (zh)	2005-10-26
IL137811A0 (en)	2001-10-31
PT1053017E (pt)	2004-12-31
KR100622716B1 (ko)	2006-09-13
WO1999040938A3 (en)	2000-08-24
ES2226338T3 (es)	2005-03-16
AU764036B2 (en)	2003-08-07
IL137811A (en)	2005-12-18
ATE275421T1 (de)	2004-09-15

Publication	Publication Date	Title
DK1053017T3 (da)	2004-11-22	Vacciner omfattende interleukin-12 og herpes simplex virusantigen
WO1999040936A3 (en)	1999-10-28	Pneumococcal and meningococcal vaccines formulated with interleukin-12
FR20C1016I1 (da)	2020-06-12
ATE315405T1 (de)	2006-02-15	Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung
CA2185470A1 (en)	1995-09-21	Compositions and methods for vaccines comprising .alpha.-galactosyl epitopes
AU7980794A (en)	1995-05-08	Methods and compositions for microencapsulation of antigens for use as vaccines
AUPR011700A0 (en)	2000-10-05	Composition comprising immunogenic virus sized particles (VSP)
PT865297E (pt)	2003-03-31	Composicoes de vacinas para administracao intranasal compreendendo quitosano e suas utilizacoes
PT851927E (pt)	2004-03-31	Compostos para imunoterapia e diagnostico de tuberculose
EP1032417A4 (en)	2001-09-05	BACTERIAL VACCINES CONTAINING ATTENUATED AUXOTROPHIC STRAINS OF LISTERIA EXPRESSING HETEROLOGIC ANTIGENS
MX9702336A (es)	1997-06-28	Composiciones de vacuna.
ATE397942T1 (de)	2008-07-15	Adjuvanszusammensetzungen zur erhöhung der immunantwort bezüglich polynukleotid-basierenden impfstoffen
WO2004032829A3 (en)	2004-12-09	Immunostimulatory compositions and methods of stimulating an immune response
FI920132A0 (fi)	1992-01-13	Stabila vaccinkompositioner innehaollande interleukiner.
WO2002062296A3 (en)	2003-02-13	Methods and compositions useful for stimulating an immune response
DK1047446T3 (da)	2004-03-29	Vaccinesammensætning til Herpes Simplex virus og fremgangsmåder til anvendelser deraf
DK0939648T3 (da)	2008-02-11	Rotavirusvaccineformuleringer
GB9818133D0 (en)	1998-10-14	Vaccine
WO1999040937A3 (en)	1999-10-28	Vaccines comprising interleukin-12 and respiratory syncytial viral antigens
AU8467201A (en)	2002-02-13	Compositions for and methods of using herpes simplex virus glycoprotein d to suppress immune responses
SE9604322D0 (sv)	1996-11-25	Bacterial antigens and vaccine compositions II
DE69637435D1 (de)	2008-03-27	Saponin-zusammensetzungen und deren verwendung
AU6761301A (en)	2001-12-17	Adjuvant composition comprising fha protein or fragment of fha protein in free form
EP1027895A3 (en)	2001-07-18	Erysipelothrix rhusiopathiae antigens and vaccine compositions
HUP9902885A1 (hu)	1999-12-28	Maláriaellenes vakcinakészítmények