DE69919984D1 - Interleukin-12 und herpes simplex virusantigen enthaltende impfstoffe - Google Patents

Interleukin-12 und herpes simplex virusantigen enthaltende impfstoffe

Info

Publication number: DE69919984D1
Authority: DE; Germany
Prior art keywords: interleukin; herpes simplex; virusantigen; containing vaccines; antigen
Prior art date: 1998-02-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69919984T

Other languages

English (en)

Other versions

DE69919984T2 (de

Inventor

M Mishkin

H Eldridge

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wyeth Holdings LLC

Wyeth LLC

Original Assignee

Wyeth Holdings LLC

Wyeth LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-12

Filing date

1999-02-10

Publication date

2004-10-14

1999-02-10 Application filed by Wyeth Holdings LLC, Wyeth LLC filed Critical Wyeth Holdings LLC

2004-10-14 Application granted granted Critical

2004-10-14 Publication of DE69919984D1 publication Critical patent/DE69919984D1/de

2005-11-17 Publication of DE69919984T2 publication Critical patent/DE69919984T2/de

2019-02-11 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Virology (AREA)
Immunology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Microbiology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

DE1999619984 1998-02-12 1999-02-10 Interleukin-12 und herpes simplex virusantigen enthaltende impfstoffe Expired - Fee Related DE69919984T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US7450398P	1998-02-12	1998-02-12
US74503P		1998-02-12
PCT/US1999/002923 WO1999040938A2 (en)	1998-02-12	1999-02-10	Vaccines comprising interleukin-12 and herpes simplex viral antigen

Publications (2)

Publication Number	Publication Date
DE69919984D1 true DE69919984D1 (de)	2004-10-14
DE69919984T2 DE69919984T2 (de)	2005-11-17

Family

ID=22119907

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE1999619984 Expired - Fee Related DE69919984T2 (de)	1998-02-12	1999-02-10	Interleukin-12 und herpes simplex virusantigen enthaltende impfstoffe

Country Status (15)

Country	Link
US (1)	US6488936B1 (de)
EP (1)	EP1053017B1 (de)
JP (1)	JP2002502884A (de)
KR (1)	KR100622716B1 (de)
CN (1)	CN1224422C (de)
AT (1)	ATE275421T1 (de)
AU (1)	AU764036B2 (de)
BR (1)	BR9907883A (de)
CA (1)	CA2320041A1 (de)
DE (1)	DE69919984T2 (de)
DK (1)	DK1053017T3 (de)
ES (1)	ES2226338T3 (de)
IL (1)	IL137811A (de)
PT (1)	PT1053017E (de)
WO (1)	WO1999040938A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ20013916A3 (cs)	1999-05-13	2002-06-12	American Cyanamid Company	Adjuvantní kombinované prostředky
ATE319833T1 (de) *	1999-12-17	2006-03-15	Wyeth Corp	Impfstoffe zur erhöhung der immunantworten gegen herpes simplex virus
US20070025958A1 (en)	2000-10-27	2007-02-01	Hadden John W	Vaccine immunotherapy
CA2950109C (en)	2000-10-27	2019-02-19	John W. Hadden	Vaccine immunotherapy for immune suppressed patients
HUP0600589A2 (en) *	2000-11-10	2006-11-28	Wyeth Corp	Adjuvant combination formulations
US6867000B2 (en)	2000-12-07	2005-03-15	Wyeth Holdings Corporation	Method of enhancing immune responses to herpes
JP2004099584A (ja)	2002-05-02	2004-04-02	Keio Gijuku	Ｈｓｖを用いた抗腫瘍剤
CN1301749C (zh) *	2005-12-09	2007-02-28	复旦大学	抗单纯疱疹病毒－2感染的多表位dna疫苗及其制备方法
US7790203B2 (en) *	2005-12-13	2010-09-07	Lowder Tom R	Composition and regimen for the treatment of herpes simplex virus, herpes zoster, and herpes genitalia epidermal herpetic lesions
US20090181078A1 (en)	2006-09-26	2009-07-16	Infectious Disease Research Institute	Vaccine composition containing synthetic adjuvant
US8273361B2 (en)	2006-09-26	2012-09-25	Infectious Disease Research Institute	Vaccine composition containing synthetic adjuvant
CA3017298C (en)	2009-05-15	2021-09-28	Irx Therapeutics, Inc.	Compositions comprising primary cell-derived biologics for enhancing immune responses in patients
LT2437753T (lt)	2009-06-05	2016-12-12	Infectious Disease Research Institute	Sintetiniai gliukopiranozillipidų adjuvantai ir juos turinčios vakcinų kompozicijos
US8729058B2 (en) *	2009-10-27	2014-05-20	Michael Zasloff	Methods and compositions for treating and preventing viral infections
CN103097543A (zh)	2009-12-08	2013-05-08	伊尔克斯治疗有限公司	逆转朗格汉斯细胞免疫抑制的方法
WO2012141984A1 (en)	2011-04-08	2012-10-18	Immune Design Corp.	Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
LT2850431T (lt)	2012-05-16	2018-06-25	Immune Design Corp.	Vakcinos, skirtos hsv-2
KR102039520B1 (ko)	2013-04-18	2019-11-01	이뮨 디자인 코포레이션	암 치료에 이용하기 위한 gla 단일요법
US9463198B2 (en)	2013-06-04	2016-10-11	Infectious Disease Research Institute	Compositions and methods for reducing or preventing metastasis
CA3023446A1 (en)	2016-05-10	2017-11-16	Hennepin Healthcare Research Institute	Cytokine signaling immunomodulators and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994022473A1 (en) *	1993-04-01	1994-10-13	University Of Washington	Use of interleukin 7 to improve vaccine potency
US5571515A (en) *	1994-04-18	1996-11-05	The Wistar Institute Of Anatomy & Biology	Compositions and methods for use of IL-12 as an adjuvant
IL114576A0 (en) *	1994-07-22	1995-11-27	Merck & Co Inc	Polynucleotide herpes virus vaccine
GB9422990D0 (en) *	1994-11-15	1995-01-04	Cortecs Ltd	Immunogenic compositions
WO1998008947A1 (en) *	1995-12-19	1998-03-05	The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services	Enhancement of dna immunization through the use of cytokines

1999
- 1999-02-10 PT PT99905946T patent/PT1053017E/pt unknown
- 1999-02-10 AU AU25981/99A patent/AU764036B2/en not_active Ceased
- 1999-02-10 KR KR1020007008769A patent/KR100622716B1/ko not_active Expired - Fee Related
- 1999-02-10 EP EP19990905946 patent/EP1053017B1/de not_active Expired - Lifetime
- 1999-02-10 WO PCT/US1999/002923 patent/WO1999040938A2/en not_active Ceased
- 1999-02-10 BR BR9907883A patent/BR9907883A/pt not_active Application Discontinuation
- 1999-02-10 CA CA 2320041 patent/CA2320041A1/en not_active Abandoned
- 1999-02-10 DE DE1999619984 patent/DE69919984T2/de not_active Expired - Fee Related
- 1999-02-10 ES ES99905946T patent/ES2226338T3/es not_active Expired - Lifetime
- 1999-02-10 CN CNB998043311A patent/CN1224422C/zh not_active Expired - Fee Related
- 1999-02-10 DK DK99905946T patent/DK1053017T3/da active
- 1999-02-10 IL IL13781199A patent/IL137811A/en not_active IP Right Cessation
- 1999-02-10 US US09/247,635 patent/US6488936B1/en not_active Expired - Fee Related
- 1999-02-10 AT AT99905946T patent/ATE275421T1/de not_active IP Right Cessation
- 1999-02-10 JP JP2000531189A patent/JP2002502884A/ja active Pending

Also Published As

Publication number	Publication date
KR20010040867A (ko)	2001-05-15
EP1053017A2 (de)	2000-11-22
JP2002502884A (ja)	2002-01-29
CA2320041A1 (en)	1999-08-19
WO1999040938A2 (en)	1999-08-19
KR100622716B1 (ko)	2006-09-13
IL137811A0 (en)	2001-10-31
BR9907883A (pt)	2000-11-14
AU2598199A (en)	1999-08-30
ES2226338T3 (es)	2005-03-16
PT1053017E (pt)	2004-12-31
WO1999040938A3 (en)	2000-08-24
IL137811A (en)	2005-12-18
AU764036B2 (en)	2003-08-07
EP1053017B1 (de)	2004-09-08
DK1053017T3 (da)	2004-11-22
US6488936B1 (en)	2002-12-03
CN1299287A (zh)	2001-06-13
DE69919984T2 (de)	2005-11-17
CN1224422C (zh)	2005-10-26
ATE275421T1 (de)	2004-09-15

Publication	Publication Date	Title
DE69919984D1 (de)	2004-10-14	Interleukin-12 und herpes simplex virusantigen enthaltende impfstoffe
WO1999040936A3 (en)	1999-10-28	Pneumococcal and meningococcal vaccines formulated with interleukin-12
FR20C1016I1 (de)	2020-06-12
AU7980794A (en)	1995-05-08	Methods and compositions for microencapsulation of antigens for use as vaccines
ES2186809T3 (es)	2003-05-16	Composiciones de vacunas para administracion intranasal, comprendiendo chitosana y su uso.
CA2185470A1 (en)	1995-09-21	Compositions and methods for vaccines comprising .alpha.-galactosyl epitopes
FI920132A0 (fi)	1992-01-13	Stabila vaccinkompositioner innehaollande interleukiner.
IS4518A (is)	1999-01-10	Nýtt lyfjaform fyrir bóluefni
MX9702336A (es)	1997-06-28	Composiciones de vacuna.
ATE454163T1 (de)	2010-01-15	Bakterielle impfstoffe, enthaltend auxotrophe attenuierte listerienstämme, welche heterologe antigene exprimieren
PT851927E (pt)	2004-03-31	Compostos para imunoterapia e diagnostico de tuberculose
ATE397942T1 (de)	2008-07-15	Adjuvanszusammensetzungen zur erhöhung der immunantwort bezüglich polynukleotid-basierenden impfstoffen
IL150602A0 (en)	2003-02-12	Proteosome influenza vaccine
WO2004032829A3 (en)	2004-12-09	Immunostimulatory compositions and methods of stimulating an immune response
WO1998053075A3 (en)	1999-04-01	Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
WO2002062296A3 (en)	2003-02-13	Methods and compositions useful for stimulating an immune response
IL130075A0 (en)	2000-02-29	A vaccine for eliciting an immune response to an antigen in an animal
WO2001039803A3 (en)	2002-02-21	Interleukin-1 muteins useful as vaccine adjuvants
DK0939648T3 (da)	2008-02-11	Rotavirusvaccineformuleringer
WO2005012538A3 (en)	2006-01-26	Accelerated vaccination
WO1999040937A3 (en)	1999-10-28	Vaccines comprising interleukin-12 and respiratory syncytial viral antigens
GB9818133D0 (en)	1998-10-14	Vaccine
DE60131975D1 (de)	2008-01-31	Anwendung des herpes simplex virus glykoproteins-d zur unterdrückung von immunantworten
DE69637435D1 (de)	2008-03-27	Saponin-zusammensetzungen und deren verwendung
DE69830156D1 (de)	2005-06-16	Zusammensetzungen zur immunverstärkung von impfstoffen

Legal Events

Date	Code	Title	Description
2005-10-06	8364	No opposition during term of opposition
2010-12-16	8339	Ceased/non-payment of the annual fee