DK1043310T3 - Biphenylamidinderivater - Google Patents
BiphenylamidinderivaterInfo
- Publication number
- DK1043310T3 DK1043310T3 DK98954747T DK98954747T DK1043310T3 DK 1043310 T3 DK1043310 T3 DK 1043310T3 DK 98954747 T DK98954747 T DK 98954747T DK 98954747 T DK98954747 T DK 98954747T DK 1043310 T3 DK1043310 T3 DK 1043310T3
- Authority
- DK
- Denmark
- Prior art keywords
- biphenylamidine
- biphenylamidine derivatives
- derivatives
- chem
- pharmaceutically acceptable
- Prior art date
Links
- LNUYLGUBVHEHEL-UHFFFAOYSA-N 2-phenylbenzenecarboximidamide Chemical class NC(=N)C1=CC=CC=C1C1=CC=CC=C1 LNUYLGUBVHEHEL-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/18—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP31969897 | 1997-11-20 | ||
| JP12749898 | 1998-05-11 | ||
| EP98954747A EP1043310B1 (en) | 1997-11-20 | 1998-11-19 | Biphenylamidine derivatives |
| PCT/JP1998/005209 WO1999026918A1 (en) | 1997-11-20 | 1998-11-19 | Biphenylamidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1043310T3 true DK1043310T3 (da) | 2004-10-25 |
Family
ID=26463455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98954747T DK1043310T3 (da) | 1997-11-20 | 1998-11-19 | Biphenylamidinderivater |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6706745B1 (ja) |
| EP (1) | EP1043310B1 (ja) |
| KR (1) | KR100581506B1 (ja) |
| CN (1) | CN1150162C (ja) |
| AT (1) | ATE268751T1 (ja) |
| AU (1) | AU744567B2 (ja) |
| BG (1) | BG63536B1 (ja) |
| BR (1) | BR9814983A (ja) |
| CA (1) | CA2310331A1 (ja) |
| DE (1) | DE69824450T2 (ja) |
| DK (1) | DK1043310T3 (ja) |
| EE (1) | EE04564B1 (ja) |
| ES (1) | ES2218866T3 (ja) |
| HR (1) | HRP20000304B1 (ja) |
| HU (1) | HUP0100085A3 (ja) |
| ID (1) | ID24846A (ja) |
| IL (1) | IL136100A (ja) |
| IS (1) | IS5497A (ja) |
| NO (1) | NO20002589L (ja) |
| NZ (1) | NZ504407A (ja) |
| PL (1) | PL340658A1 (ja) |
| PT (1) | PT1043310E (ja) |
| RU (1) | RU2197478C2 (ja) |
| SK (1) | SK7612000A3 (ja) |
| TR (1) | TR200001452T2 (ja) |
| TW (1) | TW523504B (ja) |
| UA (1) | UA52797C2 (ja) |
| WO (1) | WO1999026918A1 (ja) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010032175A (ko) * | 1997-11-20 | 2001-04-16 | 야스이 쇼사꾸 | 비페닐아미딘 유도체 |
| WO2000044380A1 (en) * | 1999-01-28 | 2000-08-03 | Teijin Limited | Release-regulating preparations |
| AU4614100A (en) * | 1999-05-17 | 2000-12-05 | Teijin Limited | Cyanobiphenyl derivatives |
| US20020065303A1 (en) * | 2000-02-01 | 2002-05-30 | Bing-Yan Zhu | Bivalent phenylene inhibitors of factor Xa |
| RU2273633C9 (ru) * | 2000-10-04 | 2006-10-20 | Киссеи Фармасьютикал Ко., Лтд. | Производные 5-амидино-2-гидроксибензолсульфонамида, содержащие их фармацевтические композиции и промежуточные продукты для их получения |
| US6316475B1 (en) * | 2000-11-17 | 2001-11-13 | Abbott Laboratories | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications |
| JPWO2002059091A1 (ja) * | 2001-01-26 | 2004-05-27 | 帝人株式会社 | シアノフェニル安息香酸誘導体の製造法 |
| CN1489575A (zh) * | 2001-01-29 | 2004-04-14 | ������������ʽ���� | 苯甲脒衍生物及其制备方法 |
| WO2002060448A1 (fr) * | 2001-01-30 | 2002-08-08 | Teijin Limited | Composition medicinale |
| AR035425A1 (es) * | 2001-01-30 | 2004-05-26 | Teijin Ltd | Cristal de diclorhidrato del acido 3-(3-amidinofenil)-5-[({[1-(iminoetil)-4-piperidil]metil}amino)metil]benzoico y proceso para prepararlo |
| US20050014787A1 (en) * | 2001-11-09 | 2005-01-20 | Masahiko Uchida | 5-amidino-2-hydroxybenzenesulfonamide derivatives medicinal compoistions containing the same medicinal use thereof and intermediates in the production thereof |
| WO2003048111A1 (fr) | 2001-11-30 | 2003-06-12 | Teijin Limited | Procede pour produire un compose d'acide 5-(3-cyanophenyl)-3-formylbenzoique |
| CA2507707C (en) | 2002-12-03 | 2011-06-21 | Axys Pharmaceuticals, Inc. | 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors |
| WO2006003881A1 (ja) * | 2004-06-30 | 2006-01-12 | Toyama Chemical Co., Ltd. | 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤 |
| CA2619745A1 (en) | 2005-08-18 | 2007-02-22 | Teijin Pharma Limited | Tablet with multiple drug-containing sections |
| CN101291656B (zh) | 2005-08-18 | 2012-11-07 | 帝人制药株式会社 | 具有准确的用量分割功能的制剂 |
| PE20070698A1 (es) | 2005-11-14 | 2007-08-17 | Teijin Pharma Ltd | Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol |
| US10464896B2 (en) | 2015-06-11 | 2019-11-05 | Basilea Pharmaceutica International AG | Efflux-pump inhibitors and therapeutic uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2550192B1 (fr) * | 1983-08-03 | 1986-04-04 | Sanofi Sa | Nouveaux derives de la benzamidine a activite antimicrobienne, leur procede de preparation, leur utilisation en tant que medicaments desinfectants ou conservateurs |
| DE4102024A1 (de) | 1991-01-24 | 1992-07-30 | Thomae Gmbh Dr K | Biphenylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| EP0567967B1 (de) * | 1992-04-28 | 1996-07-10 | Dr. Karl Thomae GmbH | Tritiumarkierte Fibrinogen-Rezeptor-Antagonisten, deren Verwendung und Verfahren zur ihrer Herstellung |
| DE4219158A1 (de) * | 1992-06-11 | 1993-12-16 | Thomae Gmbh Dr K | Biphenylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| DE19546452A1 (de) * | 1995-12-13 | 1997-06-19 | Boehringer Ingelheim Kg | Neue Phenylamidinderivate, Verfahren zu ihrer Herstelung und ihre Verwendung als Arzneimittel |
| JPH101467A (ja) * | 1996-06-13 | 1998-01-06 | Banyu Pharmaceut Co Ltd | ビフェニルアミジン誘導体 |
| DE19636689A1 (de) * | 1996-09-10 | 1998-03-12 | Boehringer Ingelheim Kg | Neue Benzamidinderivate |
| KR20010032175A (ko) * | 1997-11-20 | 2001-04-16 | 야스이 쇼사꾸 | 비페닐아미딘 유도체 |
-
1998
- 1998-11-19 DK DK98954747T patent/DK1043310T3/da active
- 1998-11-19 ES ES98954747T patent/ES2218866T3/es not_active Expired - Lifetime
- 1998-11-19 AT AT98954747T patent/ATE268751T1/de not_active IP Right Cessation
- 1998-11-19 BR BR9814983-0A patent/BR9814983A/pt not_active Application Discontinuation
- 1998-11-19 ID IDW20000955A patent/ID24846A/id unknown
- 1998-11-19 NZ NZ504407A patent/NZ504407A/en unknown
- 1998-11-19 EP EP98954747A patent/EP1043310B1/en not_active Expired - Lifetime
- 1998-11-19 IL IL13610098A patent/IL136100A/xx not_active IP Right Cessation
- 1998-11-19 CN CNB988132206A patent/CN1150162C/zh not_active Expired - Fee Related
- 1998-11-19 HR HR20000304A patent/HRP20000304B1/xx not_active IP Right Cessation
- 1998-11-19 KR KR1020007005463A patent/KR100581506B1/ko not_active Expired - Fee Related
- 1998-11-19 US US09/554,799 patent/US6706745B1/en not_active Expired - Fee Related
- 1998-11-19 TW TW087119208A patent/TW523504B/zh not_active IP Right Cessation
- 1998-11-19 UA UA2000063535A patent/UA52797C2/uk unknown
- 1998-11-19 CA CA002310331A patent/CA2310331A1/en not_active Abandoned
- 1998-11-19 HU HU0100085A patent/HUP0100085A3/hu unknown
- 1998-11-19 AU AU11740/99A patent/AU744567B2/en not_active Ceased
- 1998-11-19 SK SK761-2000A patent/SK7612000A3/sk unknown
- 1998-11-19 DE DE69824450T patent/DE69824450T2/de not_active Expired - Fee Related
- 1998-11-19 TR TR2000/01452T patent/TR200001452T2/xx unknown
- 1998-11-19 EE EEP200000298A patent/EE04564B1/xx not_active IP Right Cessation
- 1998-11-19 WO PCT/JP1998/005209 patent/WO1999026918A1/ja not_active Ceased
- 1998-11-19 PT PT98954747T patent/PT1043310E/pt unknown
- 1998-11-19 RU RU2000115947/04A patent/RU2197478C2/ru not_active IP Right Cessation
- 1998-11-19 PL PL98340658A patent/PL340658A1/xx not_active Application Discontinuation
-
2000
- 2000-05-15 IS IS5497A patent/IS5497A/is unknown
- 2000-05-17 BG BG104447A patent/BG63536B1/bg unknown
- 2000-05-19 NO NO20002589A patent/NO20002589L/no unknown
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