DK0937727T3 - Fremgangsmåde til fremstilling af opløseligt krystallinsk cefuroxim-axetil - Google Patents
Fremgangsmåde til fremstilling af opløseligt krystallinsk cefuroxim-axetilInfo
- Publication number
- DK0937727T3 DK0937727T3 DK99103410T DK99103410T DK0937727T3 DK 0937727 T3 DK0937727 T3 DK 0937727T3 DK 99103410 T DK99103410 T DK 99103410T DK 99103410 T DK99103410 T DK 99103410T DK 0937727 T3 DK0937727 T3 DK 0937727T3
- Authority
- DK
- Denmark
- Prior art keywords
- cefuroxime axetil
- preparation
- soluble crystalline
- crystalline cefuroxime
- usp
- Prior art date
Links
- 229960002620 cefuroxime axetil Drugs 0.000 title abstract 3
- KEJCWVGMRLCZQQ-YJBYXUATSA-N Cefuroxime axetil Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(=O)OC(C)OC(C)=O)=O)C(=O)\C(=N/OC)C1=CC=CO1 KEJCWVGMRLCZQQ-YJBYXUATSA-N 0.000 title 1
- 230000003287 optical effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19807248 | 1998-02-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0937727T3 true DK0937727T3 (da) | 2002-05-13 |
Family
ID=7858459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99103410T DK0937727T3 (da) | 1998-02-20 | 1999-02-22 | Fremgangsmåde til fremstilling af opløseligt krystallinsk cefuroxim-axetil |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0937727B1 (da) |
| AT (1) | ATE212638T1 (da) |
| DE (2) | DE19907521A1 (da) |
| DK (1) | DK0937727T3 (da) |
| ES (1) | ES2171056T3 (da) |
| PT (1) | PT937727E (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN190849B (da) * | 2000-07-17 | 2003-08-23 | Ranbaxy Lab Ltd | |
| DE102005019458A1 (de) | 2005-04-25 | 2006-10-26 | Grünenthal GmbH | Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil |
| DE102006019619A1 (de) * | 2006-04-25 | 2007-10-31 | Grünenthal GmbH | Kristalline Modifikation von Cefuroximaxetil |
| CN114354800B (zh) * | 2021-12-31 | 2023-04-28 | 山东大学 | 头孢呋辛酯中乙酰溴含量的分析方法 |
| CN116284050B (zh) * | 2022-12-19 | 2024-04-12 | 华北制药河北华民药业有限责任公司 | 一种高效率结晶型头孢呋辛酯转无定型粉体的方法及产品 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1094545A (en) * | 1976-02-16 | 1981-01-27 | Michael Gregson | Cephalosporin antibiotics |
| GB1571683A (en) * | 1976-02-16 | 1980-07-16 | Glaxo Operations Ltd | Ester derivatives of cefuroxime |
| YU44680B (en) * | 1982-07-30 | 1990-12-31 | Glaxo Lab Ltd | Process for obtaining very pure amorphous form of cephuroxim axetile |
| GB8320521D0 (en) * | 1983-07-29 | 1983-09-01 | Glaxo Group Ltd | Chemical process |
| US5063224A (en) * | 1990-07-09 | 1991-11-05 | Eli Lilly And Company | R-cefuroxime axetil |
| IT1277426B1 (it) * | 1995-08-03 | 1997-11-10 | Acs Dobfar Spa | Forma cristallina biodisponibile del cefuroxima axetil |
| NZ299077A (en) * | 1996-07-26 | 1998-06-26 | Apotex Inc | Preparation of amorphous cefuroxime axetil (a cephalosporin derivative) by dissolving crystalline cefuroxim axetil in a highly polar solvent, typically dmso and/or dmf |
| KR100187959B1 (ko) * | 1997-03-31 | 1999-06-01 | 윤재승 | 저융점 무정형 세푸록심 악세틸의 제조방법 |
| CA2209868C (en) * | 1997-08-15 | 2001-08-14 | Bernard Charles Sherman | Pharmaceutical compositions comprising cefuroxime axetil |
-
1999
- 1999-02-22 PT PT99103410T patent/PT937727E/pt unknown
- 1999-02-22 EP EP99103410A patent/EP0937727B1/de not_active Expired - Lifetime
- 1999-02-22 DE DE19907521A patent/DE19907521A1/de not_active Withdrawn
- 1999-02-22 DK DK99103410T patent/DK0937727T3/da active
- 1999-02-22 ES ES99103410T patent/ES2171056T3/es not_active Expired - Lifetime
- 1999-02-22 DE DE59900787T patent/DE59900787D1/de not_active Expired - Fee Related
- 1999-02-22 AT AT99103410T patent/ATE212638T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2171056T3 (es) | 2002-08-16 |
| ATE212638T1 (de) | 2002-02-15 |
| DE59900787D1 (de) | 2002-03-14 |
| PT937727E (pt) | 2002-07-31 |
| DE19907521A1 (de) | 1999-11-04 |
| EP0937727B1 (de) | 2002-01-30 |
| EP0937727A1 (de) | 1999-08-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA66852C2 (uk) | Похідні та аналоги 3-арилпропіонової кислоти, спосіб їх отримання, фармацевтична композиція (варіанти) та спосіб профілактики та/або лікування асоційованих з резистентністю до інсуліну клінічних станів | |
| BG103268A (en) | Propionic acid derivatives and their application | |
| BG92179A (bg) | Метод за получаване на 7-заместена-хепт-6-еноена и -хептаноена киселина и техни производни и междинни съединения | |
| WO1990009993A3 (en) | Method for the synthesis of huperzine a and analogs thereof and compounds useful therein | |
| HK117993A (en) | Glycerol derivatives | |
| DK0937727T3 (da) | Fremgangsmåde til fremstilling af opløseligt krystallinsk cefuroxim-axetil | |
| ATE214051T1 (de) | Substituierte tetrahydropyridinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel | |
| DE69132578D1 (de) | Cephemderivate | |
| AU656674B2 (en) | New thiochroman compounds, processes for the preparation thereof, and pharmaceutical compositions containing them | |
| ATE127465T1 (de) | Isoindolinon-derivat, seine herstellung und dieses enthaltende pharmazeutische zusammen setzungen. | |
| EP1136488A4 (en) | SF2809-I, II, III. VI, V AND VI COMPOUNDS WITH CHYMASE INHIBITING EFFECT | |
| AU2729588A (en) | New substituted derivatives of 20,21-dinoreburnamenine, process for preparing them and the new intermediate products so obtained, their application as drugs and the pharmaceutical compositions containing them | |
| AU668398B2 (en) | New aminoalkylchromones, processes for the preparation thereof, and pharmaceutical compositions containing them | |
| ATE117682T1 (de) | Substituierte benzothiazolinone, ihre herstellung und sie enthaltende pharmazeutische zusammenstellungen. | |
| IE780090L (en) | 2,9-dioxatricyclo [4.3.1.0(3,7)] decanes | |
| CA2071093A1 (fr) | Derives de benzoate d'ethanolamine, leur procede de preparation et les compositions pharmaceutiques les renfermant | |
| JPS54122737A (en) | Remedy for pericementosis | |
| AU1621392A (en) | New 1-amidooctahydropyrido(2,1-c)(1,4)oxazine compounds, processes for preparing these and pharmaceutical compositions containing them | |
| IE873474L (en) | Dibenzo£be|oxepinacetic acid derivatives, their preparation¹and pharmaceutical compositions containing them | |
| AU659738B2 (en) | New pyrrolothienopyrazine compounds, processes for the preparation thereof, and pharmaceutical compositions containing them | |
| AU7753994A (en) | New cyclised analogues of fatty acid metabolites a process for their preparation and pharmaceutical compositions containing them | |
| ES8302624A1 (es) | "procedimiento para la preparacion del acido (2',4'-difluoro-4-bifenil)-oxiacetico". | |
| JPS5412382A (en) | Optical resolution of dl-2-(p-methoxybenzyl)-1,3,4-trimethyl-1,2,5,6,- tetrahydropyridine |