DK0934078T3 - Permeabilitetsfremmere til transdermal administrering af aktivstoffer, anordninger og fremgangsmåde til fremstilling deraf - Google Patents
Permeabilitetsfremmere til transdermal administrering af aktivstoffer, anordninger og fremgangsmåde til fremstilling derafInfo
- Publication number
- DK0934078T3 DK0934078T3 DK97912815T DK97912815T DK0934078T3 DK 0934078 T3 DK0934078 T3 DK 0934078T3 DK 97912815 T DK97912815 T DK 97912815T DK 97912815 T DK97912815 T DK 97912815T DK 0934078 T3 DK0934078 T3 DK 0934078T3
- Authority
- DK
- Denmark
- Prior art keywords
- drug
- transdermal administration
- permeation enhancer
- processes
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title 1
- 230000035699 permeability Effects 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 4
- 239000003961 penetration enhancing agent Substances 0.000 abstract 3
- 239000011159 matrix material Substances 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 150000001346 alkyl aryl ethers Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- -1 aryl carboxylic acid esters Chemical class 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- CXHHBNMLPJOKQD-UHFFFAOYSA-N methyl hydrogen carbonate Chemical class COC(O)=O CXHHBNMLPJOKQD-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 230000001839 systemic circulation Effects 0.000 abstract 1
- 238000013271 transdermal drug delivery Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3042496P | 1996-10-24 | 1996-10-24 | |
| PCT/US1997/018956 WO1998017315A2 (fr) | 1996-10-24 | 1997-10-23 | Agents facilitant la permeation et destines a des compositions, des dispositifs et des procedes d'apport transdermique de medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0934078T3 true DK0934078T3 (da) | 2003-04-14 |
Family
ID=21854141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97912815T DK0934078T3 (da) | 1996-10-24 | 1997-10-23 | Permeabilitetsfremmere til transdermal administrering af aktivstoffer, anordninger og fremgangsmåde til fremstilling deraf |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6004578A (fr) |
| EP (1) | EP0934078B1 (fr) |
| JP (1) | JP2001502693A (fr) |
| AT (1) | ATE229817T1 (fr) |
| AU (1) | AU4990797A (fr) |
| CA (1) | CA2264687C (fr) |
| DE (1) | DE69718037T2 (fr) |
| DK (1) | DK0934078T3 (fr) |
| ES (1) | ES2191834T3 (fr) |
| WO (1) | WO1998017315A2 (fr) |
Families Citing this family (111)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL345087A1 (en) * | 1998-06-25 | 2001-12-03 | Lavipharm Lab | A device and method for the treatment of erectile dysfunction |
| US6825234B2 (en) * | 1998-12-10 | 2004-11-30 | Nexmed (Holdings) , Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
| US20070191320A1 (en) * | 1998-12-10 | 2007-08-16 | Nexmed Holdings, Inc. | Methods of treatment for female sexual arousal disorder |
| US6486207B2 (en) * | 1998-12-10 | 2002-11-26 | Nexmed (Holdings), Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
| US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| WO2000045790A2 (fr) † | 1999-02-08 | 2000-08-10 | Alza Corporation | Excipients visqueux a phase unique non aqueux stables et formulations utilisant ces excipients |
| DE60045211D1 (de) | 1999-02-19 | 2010-12-23 | Takeda Pharmaceutical | Präparationen zur perkutanen aufnahme von zusammnesetzungen die einen angiotensin-ii-rezeptorantagonismus aufweisen |
| AU6595100A (en) * | 1999-08-20 | 2001-03-19 | Takeda Chemical Industries Ltd. | Percutaneous absorption agents |
| US7179483B2 (en) * | 2000-04-26 | 2007-02-20 | Watson Pharmaceuticals, Inc. | Compositions and methods for transdermal oxybutynin therapy |
| USRE44145E1 (en) | 2000-07-07 | 2013-04-09 | A.V. Topchiev Institute Of Petrochemical Synthesis | Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties |
| US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| WO2002054996A2 (fr) * | 2000-10-23 | 2002-07-18 | Euro Celtique Sa | Dispositif transdermique de la terazosine et procedes associes |
| CZ307857B6 (cs) * | 2001-03-16 | 2019-07-03 | Alza Corporation | Transdermální náplast pro podávání fentanylu nebo jeho analogu |
| US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
| US6521613B2 (en) | 2001-04-10 | 2003-02-18 | Allergan, Inc. | Lactam compounds for penetration enhancement |
| ATE502657T1 (de) | 2001-05-01 | 2011-04-15 | Av Topchiev Inst Petrochemical | Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung |
| EP1390085B1 (fr) | 2001-05-01 | 2009-08-05 | A.V. Topchiev Institute of Petrochemical Synthesis | Compositions d'hydrogel |
| US8206738B2 (en) | 2001-05-01 | 2012-06-26 | Corium International, Inc. | Hydrogel compositions with an erodible backing member |
| US20050215727A1 (en) | 2001-05-01 | 2005-09-29 | Corium | Water-absorbent adhesive compositions and associated methods of manufacture and use |
| US20050113510A1 (en) | 2001-05-01 | 2005-05-26 | Feldstein Mikhail M. | Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components |
| US8840918B2 (en) | 2001-05-01 | 2014-09-23 | A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences | Hydrogel compositions for tooth whitening |
| US8541021B2 (en) | 2001-05-01 | 2013-09-24 | A.V. Topchiev Institute Of Petrochemical Synthesis | Hydrogel compositions demonstrating phase separation on contact with aqueous media |
| DE10154324A1 (de) * | 2001-11-06 | 2003-08-07 | Merz Pharma Gmbh & Co Kgaa | Topisch applizierbare Zusammensetzungen mit externer Wirkstoffdepotbildung, deren Herstellung sowie deren Verwendung |
| US20040033253A1 (en) * | 2002-02-19 | 2004-02-19 | Ihor Shevchuk | Acyl opioid antagonists |
| TW200404581A (en) * | 2002-04-23 | 2004-04-01 | Alza Corp | Transdermal analgesic systems with reduced abuse potential |
| SI1513532T1 (sl) | 2002-06-10 | 2007-08-31 | Euro Celtique Sa | Sistemi za odstranjevanje priprav za transdermalno oddajanje za preprečevanje zlorabe učinkovin, ki jih vsebujejo |
| WO2004017941A2 (fr) * | 2002-08-20 | 2004-03-04 | Euro-Celtique, S.A. | Forme posologique transdermique comprenant un principe actif, un sel et une forme de base libre d'un repulsif |
| CN100340395C (zh) | 2002-08-30 | 2007-10-03 | 阿尔扎公司 | 多层层压背衬结构体 |
| US20040057907A1 (en) * | 2002-09-23 | 2004-03-25 | Leonard Mackles | Dri-nasal sprays |
| IL152575A (en) * | 2002-10-31 | 2008-12-29 | Transpharma Medical Ltd | A skin-to-skin transmission system of water-insoluble drugs |
| IL152573A (en) * | 2002-10-31 | 2009-11-18 | Transpharma Medical Ltd | A system for the transmission through the skin of a medical preparation against vomiting and nausea |
| CA2729967C (fr) * | 2002-12-13 | 2018-01-16 | Schering-Plough Healthcare Products, Inc. | Utilisation d'un appareil de distribution d'ingredient transdermique ou transmucosique |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| US20040202708A1 (en) * | 2003-04-14 | 2004-10-14 | 3M Innovative Properties Company | Transdermal drug delivery device with translucent inorganic barrier layer |
| MY141815A (en) | 2003-04-30 | 2010-06-30 | Purdue Pharma Lp | Tamper-resistant transdermal dosage form comprising an active agent component and an adverse agent component at the distal site of the active agent layer |
| US8790689B2 (en) | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
| US20040219198A1 (en) * | 2003-05-01 | 2004-11-04 | 3M Innovative Properties Company | Transdermal drug delivery device with multilayer backing |
| US7563748B2 (en) * | 2003-06-23 | 2009-07-21 | Cognis Ip Management Gmbh | Alcohol alkoxylate carriers for pesticide active ingredients |
| EP1648363B1 (fr) | 2003-07-03 | 2019-03-06 | Corium International, Inc. | Pansement, dispositif d'administration d'ingredient et dispositif de fixation intraveineux et procede associe |
| EP1651197A1 (fr) | 2003-07-28 | 2006-05-03 | ALZA Corporation | Systeme d'administration transdermique contenant de la warfarine |
| US20080020028A1 (en) * | 2003-08-20 | 2008-01-24 | Euro-Celtique S.A. | Transdermal dosage form comprising an active agent and a salt and a free-base form of an adverse agent |
| EP2269606A3 (fr) * | 2003-10-30 | 2012-04-25 | ALZA Corporation | Systèmes analgésiques transdermiques disposant d'un potentiel d'abus réduit |
| CN102764247B (zh) | 2004-01-30 | 2016-04-20 | 考里安国际公司 | 递送活性剂的快速溶解膜 |
| WO2006017807A2 (fr) | 2004-08-05 | 2006-02-16 | Corium International, Inc. | Composition d'adhesif |
| KR20070053267A (ko) * | 2004-08-20 | 2007-05-23 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 반투명 보호 필름을 갖는 경피 약물 전달 장치 |
| EP1802665B1 (fr) * | 2004-10-19 | 2009-08-05 | 3M Innovative Properties Company | Procede pour fabriquer des adhesifs sensibles a la pression |
| US8252320B2 (en) | 2004-10-21 | 2012-08-28 | Durect Corporation | Transdermal delivery system for sufentanil |
| US8246977B2 (en) | 2004-10-21 | 2012-08-21 | Durect Corporation | Transdermal delivery systems |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| WO2006083761A2 (fr) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solutions de solvant/polymere utilisees comme vehicules de suspension |
| US20060216350A1 (en) * | 2005-03-24 | 2006-09-28 | Dow Gordon J | Ganglionic blocking agents for the treatment of epithelial diseases |
| PT1895994E (pt) * | 2005-05-13 | 2010-12-03 | Alza Corp | Sistema de administração de medicamentos de camada múltipla com barreira contra o fluxo de material do reservatório |
| CN101232875B (zh) * | 2005-06-10 | 2014-06-25 | 3M创新有限公司 | 处理粘合层叠片片段的方法 |
| US20070134310A1 (en) * | 2005-09-23 | 2007-06-14 | Nedberge Diane E | Transdermal risperidone delivery system |
| US20070104771A1 (en) * | 2005-09-23 | 2007-05-10 | Jay Audett | Transdermal galantamine delivery system |
| US8383149B2 (en) * | 2005-09-23 | 2013-02-26 | Alza Corporation | High enhancer-loading polyacrylate formulation for transdermal applications |
| WO2007035940A2 (fr) * | 2005-09-23 | 2007-03-29 | Alza Corporation | Systeme d'administration de norelgestromine par voie transdermique |
| US20070087055A1 (en) * | 2005-10-14 | 2007-04-19 | David Jan | Directly compressible extended release alprazolam formulation |
| WO2007046102A2 (fr) | 2005-10-19 | 2007-04-26 | Menni Menashe Zinger | Methodes destinees a traiter l'hyperhidrose |
| MX2008014870A (es) | 2006-05-30 | 2009-02-12 | Intarcia Therapeutics Inc | Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas. |
| US20070278289A1 (en) * | 2006-05-31 | 2007-12-06 | Toshiba Tec Kabushiki Kaisha | Payment adjusting apparatus and program therefor |
| MX2009001114A (es) | 2006-08-09 | 2009-02-10 | Intarcia Therapeutics Inc | Sistemas de suministro osmotico y ensambles de piston. |
| EP2124907B1 (fr) | 2007-03-19 | 2018-05-30 | Vita Sciences, Llc | Timbre transdermique et méthode pour l'administration de vitamine b12 |
| CN104000779A (zh) | 2007-04-23 | 2014-08-27 | 精达制药公司 | 促胰岛素释放肽的混悬制剂及其应用 |
| US9814422B2 (en) | 2007-08-06 | 2017-11-14 | The Regents Of The University Of California | Compositions for solubilizing cells and/or tissue |
| US9909098B2 (en) | 2007-08-06 | 2018-03-06 | The Regents Of The University Of California | Methods of tissue-based diagnosis |
| US20090258061A1 (en) * | 2007-10-15 | 2009-10-15 | Johnson & Johnson | Once-a-day replacement transdermal administration of fentanyl |
| CA2726861C (fr) | 2008-02-13 | 2014-05-27 | Intarcia Therapeutics, Inc. | Dispositifs, formulations et methodes d'administration de plusieurs agents benefiques |
| US20100080842A1 (en) * | 2008-09-30 | 2010-04-01 | Jianye Wen | Transdermal extended-delivery donepezil compositions and methods for using the same |
| AU2010204986B2 (en) * | 2009-01-14 | 2016-06-02 | Corium International, Inc. | Transdermal administration of tamsulosin |
| CN104523661A (zh) | 2009-02-06 | 2015-04-22 | 南加利福尼亚大学 | 含有单萜的治疗组合物 |
| DK2462246T3 (da) | 2009-09-28 | 2017-11-06 | Intarcia Therapeutics Inc | Hurtig etablering og/eller afslutning af væsentlig steady-state-lægemiddelafgivelse |
| WO2011066493A1 (fr) | 2009-11-30 | 2011-06-03 | 3M Innovative Properties Company | Feuille barriere adaptable, procedes et dispositif |
| US8507734B2 (en) | 2010-03-03 | 2013-08-13 | Neonc Technologies Inc. | Pharmaceutical compositions comprising monoterpenes |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| RU2013148120A (ru) * | 2011-03-31 | 2015-05-10 | Акорда Терапьютикс, Инк. | Интраназальные фармацевтические композиции на основе бензодиазепина |
| WO2013090353A1 (fr) | 2011-12-16 | 2013-06-20 | 3M Innovative Properties Company | Pansement adhésif composite pliable |
| WO2013096026A1 (fr) | 2011-12-21 | 2013-06-27 | 3M Innovative Properties Company | Assemblage de patch adhésif transdermique doté d'une série de micro-aiguilles amovibles et son procédé d'utilisation |
| JP6576039B2 (ja) | 2011-12-21 | 2019-09-18 | スリーエム イノベイティブ プロパティズ カンパニー | オーバーレイライナを有する粘着パッチ組立体、並びにそれを作製するためのシステム及び方法 |
| IN2014MN02536A (fr) * | 2012-05-16 | 2015-09-04 | Univ California | |
| US9782574B2 (en) | 2012-10-10 | 2017-10-10 | 3M Innovative Properties Company | Force-controlled applicator for applying a microneedle device to skin |
| CN104797287B (zh) | 2012-11-16 | 2017-12-26 | 3M创新有限公司 | 力控施用装置 |
| SG11201507885TA (en) | 2013-03-22 | 2015-11-27 | 3M Innovative Properties Co | Microneedle applicator comprising a counter assembly |
| EP3003459B1 (fr) | 2013-05-31 | 2018-06-20 | 3M Innovative Properties Company | Appareil d'injection à micro-aiguille comprenant un actionneur inversé |
| JP6494602B2 (ja) | 2013-05-31 | 2019-04-03 | スリーエム イノベイティブ プロパティズ カンパニー | 二重カバーを備えるマイクロニードル注射装置 |
| US9872975B2 (en) | 2013-05-31 | 2018-01-23 | 3M Innovative Properties Company | Microneedle injection and infusion apparatus and method of using same |
| US9642895B2 (en) | 2013-08-12 | 2017-05-09 | 3M Innovative Properties Company | Peptides for enhancing transdermal delivery |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| EP3020398A1 (fr) | 2014-11-17 | 2016-05-18 | Nitto Denko Corporation | Composés et formulations pour réduire une cicatrice |
| CN107107598B (zh) | 2014-12-18 | 2019-11-22 | 3M创新有限公司 | 处理粘合层合物贴剂的方法 |
| US10925639B2 (en) | 2015-06-03 | 2021-02-23 | Intarcia Therapeutics, Inc. | Implant placement and removal systems |
| EP3331547A4 (fr) | 2015-08-05 | 2019-08-21 | Children's Medical Center Corporation | Compositions ayant des amplificateurs de perméation pour l'administration de médicaments |
| US10966936B2 (en) | 2015-12-30 | 2021-04-06 | Corium, Inc. | Systems comprising a composite backing and methods for long term transdermal administration |
| CN108601749A (zh) | 2016-02-05 | 2018-09-28 | 3M创新有限公司 | 具有氟代硅氧烷剥离衬件的透皮药物递送体系 |
| EP3441382B1 (fr) * | 2016-04-05 | 2023-08-30 | Moresco Corporation | Composé d'oxa-acide |
| MA53353A (fr) | 2016-05-16 | 2021-06-09 | Intarcia Therapeutics Inc | Polypeptides sélectifs pour le récepteur du glucagon et méthodes pour leur utilisation |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| CA3028436A1 (fr) | 2016-06-23 | 2017-12-28 | Corium International, Inc. | Matrice adhesive a un domaine hydrophile, un domaine hydrophobes et un agent therapeutique |
| US9993466B2 (en) | 2016-07-27 | 2018-06-12 | Corium International, Inc. | Donepezil transdermal delivery system |
| WO2018022814A1 (fr) | 2016-07-27 | 2018-02-01 | Corium International, Inc. | Systèmes d'administration transdermique à pharmacocinétique bioéquivalent à l'administration orale |
| MX2019001104A (es) | 2016-07-27 | 2019-10-02 | Corium Int Inc | Sistemas de suministro transdermico de memantina. |
| EP3287462A1 (fr) | 2016-08-25 | 2018-02-28 | Nitto Denko Corporation | Dérivés d'isosorbide pour traiter les films bactériens |
| KR20190104039A (ko) | 2017-01-03 | 2019-09-05 | 인타르시아 세라퓨틱스 인코포레이티드 | Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법 |
| US11219688B2 (en) * | 2017-03-03 | 2022-01-11 | Moresco Corporation | Absorption promoter and use for same |
| US11173132B2 (en) | 2017-12-20 | 2021-11-16 | Corium, Inc. | Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point |
| JP7325425B2 (ja) | 2018-02-08 | 2023-08-14 | ネオンク テクノロジーズ インク． | 血液脳関門を透過性にする方法 |
| WO2019194871A1 (fr) * | 2018-04-05 | 2019-10-10 | Erbst Steven Robert | Bandage élastique thérapeutique pour moduler le système endocannabinoïde |
| WO2019217536A1 (fr) * | 2018-05-08 | 2019-11-14 | University Of Connecticut | Formulation anesthésique locale à action prolongée |
| USD933219S1 (en) | 2018-07-13 | 2021-10-12 | Intarcia Therapeutics, Inc. | Implant removal tool and assembly |
| WO2021022033A1 (fr) * | 2019-07-30 | 2021-02-04 | Leung Kai P | Composite stratifié pour le traitement et la prévention de cicatrices |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1011949A (en) * | 1964-10-27 | 1965-12-01 | Vacu Blast Ltd | Centrifugal wheel blasting machine |
| US3527864A (en) * | 1966-11-18 | 1970-09-08 | Procter & Gamble | Compositions for topical application to animal tissue and method of enhancing penetration thereof |
| US3472931A (en) * | 1969-01-17 | 1969-10-14 | Foster Milburn Co | Percutaneous absorption with lower alkyl amides |
| US3598123A (en) * | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3797494A (en) * | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
| US3731663A (en) * | 1971-01-08 | 1973-05-08 | Hollins J R | Vehicle engine fuel control accelerator override |
| US3903256A (en) * | 1972-02-07 | 1975-09-02 | Procter & Gamble | Compositions for topical application of animal tissue and method of enhancing penetration thereof |
| US3896238A (en) * | 1972-04-05 | 1975-07-22 | Procter & Gamble | Dermatological compositions |
| US3952099A (en) * | 1973-03-13 | 1976-04-20 | The Procter & Gamble Company | Dermatological compositions |
| US4046886A (en) * | 1975-01-17 | 1977-09-06 | The Procter & Gamble Company | Dermatological compositions |
| US4144317A (en) * | 1975-05-30 | 1979-03-13 | Alza Corporation | Device consisting of copolymer having acetoxy groups for delivering drugs |
| US4130667A (en) * | 1976-01-12 | 1978-12-19 | The Procter & Gamble Company | Dermatological compositions |
| US4335115A (en) * | 1976-11-01 | 1982-06-15 | The Procter & Gamble Company | Anti-acne composition |
| US4299826A (en) * | 1979-10-12 | 1981-11-10 | The Procter & Gamble Company | Anti-acne composition |
| US4286592A (en) * | 1980-02-04 | 1981-09-01 | Alza Corporation | Therapeutic system for administering drugs to the skin |
| US4314557A (en) * | 1980-05-19 | 1982-02-09 | Alza Corporation | Dissolution controlled active agent dispenser |
| FR2495934A1 (fr) * | 1980-12-15 | 1982-06-18 | Cird | Composition pour le traitement du psoriasis a base d'une dihydroxy-1,8 anthrone-9 substituee en position 10 |
| US4379454A (en) * | 1981-02-17 | 1983-04-12 | Alza Corporation | Dosage for coadministering drug and percutaneous absorption enhancer |
| US4343798A (en) * | 1981-06-23 | 1982-08-10 | The Procter & Gamble Company | Topical antimicrobial anti-inflammatory compositions |
| US4849226A (en) * | 1981-06-29 | 1989-07-18 | Alza Corporation | Method for increasing oxygen supply by administering vasodilator |
| US4435180A (en) * | 1982-05-25 | 1984-03-06 | Alza Corporation | Elastomeric active agent delivery system and method of use |
| US4559222A (en) * | 1983-05-04 | 1985-12-17 | Alza Corporation | Matrix composition for transdermal therapeutic system |
| US4573999A (en) * | 1983-10-14 | 1986-03-04 | Netto Daniel J | Human breast prosthesis |
| US4704282A (en) * | 1984-06-29 | 1987-11-03 | Alza Corporation | Transdermal therapeutic system having improved delivery characteristics |
| US4568343A (en) * | 1984-10-09 | 1986-02-04 | Alza Corporation | Skin permeation enhancer compositions |
| US4645502A (en) * | 1985-05-03 | 1987-02-24 | Alza Corporation | Transdermal delivery of highly ionized fat insoluble drugs |
| US4908027A (en) * | 1986-09-12 | 1990-03-13 | Alza Corporation | Subsaturated transdermal therapeutic system having improved release characteristics |
| US4863970A (en) * | 1986-11-14 | 1989-09-05 | Theratech, Inc. | Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols |
| US4940586A (en) * | 1987-02-26 | 1990-07-10 | Alza Corporation | Skin permeation enhancer compositions using sucrose esters |
| US4900555A (en) * | 1987-02-26 | 1990-02-13 | Alza Corporation | Skin permeation enhancer compositions using sucrose esters |
| US4816258A (en) * | 1987-02-26 | 1989-03-28 | Alza Corporation | Transdermal contraceptive formulations |
| US4746515A (en) * | 1987-02-26 | 1988-05-24 | Alza Corporation | Skin permeation enhancer compositions using glycerol monolaurate |
| US4865848A (en) * | 1987-02-26 | 1989-09-12 | Alza Corporation | Skin permeation enhancer compositions using sucrose esters |
| US4788062A (en) * | 1987-02-26 | 1988-11-29 | Alza Corporation | Transdermal administration of progesterone, estradiol esters, and mixtures thereof |
| US4820720A (en) * | 1987-08-24 | 1989-04-11 | Alza Corporation | Transdermal drug composition with dual permeation enhancers |
| US4764379A (en) * | 1987-08-24 | 1988-08-16 | Alza Corporation | Transdermal drug delivery device with dual permeation enhancers |
| US4943435A (en) * | 1987-10-05 | 1990-07-24 | Pharmetrix Corporation | Prolonged activity nicotine patch |
| US4863738A (en) * | 1987-11-23 | 1989-09-05 | Alza Corporation | Skin permeation enhancer compositions using glycerol monooleate |
| US5378730A (en) * | 1988-06-09 | 1995-01-03 | Alza Corporation | Permeation enhancer comprising ethanol and monoglycerides |
| US5004610A (en) * | 1988-06-14 | 1991-04-02 | Alza Corporation | Subsaturated nicotine transdermal therapeutic system |
| US5053327A (en) * | 1988-09-20 | 1991-10-01 | The United States Of America As Represented By The Secretary Of Agriculture | High affinity monoclonal antibodies to bowman-birk inhibitor and immunoassay methods |
| US4973468A (en) * | 1989-03-22 | 1990-11-27 | Cygnus Research Corporation | Skin permeation enhancer compositions |
| US5059426A (en) * | 1989-03-22 | 1991-10-22 | Cygnus Therapeutic Systems | Skin permeation enhancer compositions, and methods and transdermal systems associated therewith |
| JP2820306B2 (ja) * | 1990-02-27 | 1998-11-05 | 積水化学工業株式会社 | 経皮吸収製剤 |
| US5314694A (en) * | 1990-10-29 | 1994-05-24 | Alza Corporation | Transdermal formulations, methods and devices |
| DE4115849A1 (de) * | 1991-05-15 | 1992-11-19 | Lohmann Therapie Syst Lts | Penetrationsfoerdernde substanz |
| JP3786684B2 (ja) * | 1992-05-13 | 2006-06-14 | アルザ・コーポレーション | オキシブチニンの経皮投与 |
| ATE183926T1 (de) * | 1993-09-29 | 1999-09-15 | Alza Corp | Hautpermeabilitaetserhöher bestehend aus monoglycerid/laktat estern |
| ES2160727T3 (es) * | 1994-12-24 | 2001-11-16 | Pacific Corp | Parches medicinales para administracion percutanea. |
| US6572879B1 (en) * | 1995-06-07 | 2003-06-03 | Alza Corporation | Formulations for transdermal delivery of pergolide |
-
1997
- 1997-10-23 AT AT97912815T patent/ATE229817T1/de not_active IP Right Cessation
- 1997-10-23 CA CA002264687A patent/CA2264687C/fr not_active Expired - Fee Related
- 1997-10-23 US US08/956,379 patent/US6004578A/en not_active Expired - Lifetime
- 1997-10-23 ES ES97912815T patent/ES2191834T3/es not_active Expired - Lifetime
- 1997-10-23 WO PCT/US1997/018956 patent/WO1998017315A2/fr not_active Ceased
- 1997-10-23 JP JP10519563A patent/JP2001502693A/ja not_active Ceased
- 1997-10-23 AU AU49907/97A patent/AU4990797A/en not_active Abandoned
- 1997-10-23 DK DK97912815T patent/DK0934078T3/da active
- 1997-10-23 DE DE69718037T patent/DE69718037T2/de not_active Expired - Fee Related
- 1997-10-23 EP EP97912815A patent/EP0934078B1/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE229817T1 (de) | 2003-01-15 |
| CA2264687C (fr) | 2006-04-25 |
| US6004578A (en) | 1999-12-21 |
| WO1998017315A3 (fr) | 1998-07-02 |
| EP0934078A2 (fr) | 1999-08-11 |
| EP0934078B1 (fr) | 2002-12-18 |
| DE69718037T2 (de) | 2003-07-10 |
| CA2264687A1 (fr) | 1998-04-30 |
| JP2001502693A (ja) | 2001-02-27 |
| AU4990797A (en) | 1998-05-15 |
| DE69718037D1 (de) | 2003-01-30 |
| ES2191834T3 (es) | 2003-09-16 |
| WO1998017315A2 (fr) | 1998-04-30 |
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